Giants in History - Asia's Women in Science

Research stands on the shoulders of those who came before us. Here we celebrate some of Asia's pioneering female scientists. If you would like to suggest a researcher, please email us at info AT researchsea.com. Additionally, check out our article on Addressing gender bias in STEM communications and compilation of organizations working to support women in research today.

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While assisting my nieces on Asian pioneers in science, I came upon your Giants in History. Thank you, love the site, really helps to inspire young people to enter the science fields.

Dal Basi

Anna Mani

The scientist who enabled the precise measurement of weather

Anna Mani (23 August 1918 – 16 August 2001) was an Indian meteorologist who contributed significantly to the understanding of solar radiation, ozone and wind energy by developing a wide range of measurement tools. One of India’s pioneering female scientists, Mani excelled in the male-dominated area of meteorology and became the Deputy Director-General of the India Meteorological Department. She also held several important positions in the World Meteorological Organization (WMO). Mani’s early research on the spectroscopy of diamonds and rubies at the Indian Institute of Science resulted in five research papers and a PhD dissertation. However, she was not awarded a PhD as she did not have a Master’s degree. Undaunted, Mani studied meteorological instruments at Imperial College London. Dedicated to accuracy, she became an expert at designing meteorological instruments, such as ozone and radiation measuring devices, and started a company to manufacture them. Also passionate about nature, trekking and bird-watching, Mani advised young professionals this way: “We have only one life. First equip yourself for the job, make full use of your talents and then love and enjoy the work, making the most of being out of doors and in contact with nature.”

Saruhashi Nukada

Measuring the oceans' capacity to protect the planet

Japanese geochemist Katsuko Saruhashi (22 March 1920 – 29 September 2007) developed the first method and tools for measuring carbon dioxide in seawater, which became known as Saruhashi’s Table. Her work showed that the Pacific Ocean releases twice as much carbon dioxide as it absorbs, indicating that global warming could not be substantially mitigated by seawater’s capacity to absorb carbon dioxide. Saruhashi also developed a sensitive method for measuring the amounts of radioactive isotopes Cesium-137 and Strontium-90 in seawater. Her research on the radioactive fallout from nuclear testing at Bikini Atoll helped to determine limits for oceanic nuclear testing. Her childhood fascination with rain coupled with her parents' encouragement towards technical knowledge and financial independence led to her earning a degree from the Imperial Women's College of Science, now known as Toho University. Later, she was the first woman to obtain a Ph.D. in chemistry from the University of Tokyo and the first woman elected to the Science Council of Japan, she was a strong proponent of equal opportunities for women in science. She established the Society of Japanese Women Scientists as well as the Saruhashi Prize, which is awarded yearly to a female scientist who serves as a role model for younger women scientists. (Photo provided by Toho University)

Youyou

The scientist who discovered artemisinin

Tu Youyou (born 30 December 1930) is a Chinese pharmaceutical scientist who was awarded the 2015 Nobel Prize in Physiology or Medicine for her work on extracting artemisin from sweet wormwood to treat malaria. Tu performed her research during the Cultural Revolution in China, when scientists were persecuted. Trained in traditional Chinese medicine, she screened over 2,000 traditional Chinese recipes and made 380 herbal extracts, from 200 herbs, before discovering that artemisinin from sweet wormwood could inhibit the malaria parasite. Her work has helped save millions of lives in South China, Southeast Asia, Africa, and South America where malaria is prevalent. Photo shows her talking with her tutor Lou Zhicen at the China Academy of Chinese Medical Sciences in the 1950s.

Esther Park

The first female doctor in Korea

Esther Park (1877-1910), born Kim Jeom-dong, was the first female Korean physician to practise modern medicine in Korea. As a student, Park worked as a translator for American medical missionary Rosetta Sherwood Hall, who inspired Park to become a physician. After studying medicine in the US, Park returned to Korea and worked at the nation’s first hospital for women, Bogu-yeogwan. During the first 10 months there, Park helped more than 3,000 patients. She often travelled to remote villages, providing free medical services. Recognizing the importance of female education, she also trained the first generation of Korean female doctors.  

Gloria Lim

The pioneer of fungi in Singapore

Gloria Lim (1930 - 11 July 2022) was a mycologist from Singapore who studied tropical fungi. One of the first students to attend University of Malaya when it was founded in 1949, she graduated as one of the two Botany Honours students from the inaugural class. Lim went on to become the first female Dean of the Faculty of Science at the University of Singapore, now the National University of Singapore. Over the course of her career, Lim published 140 research papers, wrote several books on fungi and consulted for private companies and public sectors. She served on the scientific advisory board of MycoBiotech, a company that produces medicinal mushrooms and helped the Ministry of Defence solve the problem of mould growth in their underground storage bunkers. Lim also set up a repository of little-known fungi collected from the region. Her work brought attention to the often neglected field of mycology.

Ogino Ginko

The first registered female doctor of modern medicine in Japan

Ogino Ginko (3 March 1851 – 23 June 1913) was the first registered female doctor to practise modern medicine in Japan. After contracting gonorrhoea from her first husband and being embarrassed from having to seek medical attention from male doctors, Ginko resolved to become a doctor to help women in similar situations. She graduated from Tokyo Women's Normal School (present-day Ochanomizu University) and despite facing prejudice, took her medical practitioner’s examination in 1885. Ogino opened the Ogino Hospital specializing in obstetrics and gynaecology. She was also the staff doctor at the girls’ school of the Meiji Gakuin University. Additionally, Ogino ran a medical practice in Hokkaido and a hospital in Tokyo.  

Bibha Chowdhuri

The physicist who studied cosmic rays

Bibha Chowdhuri (1913 – 2 June 1991) was an Indian physicist who researched on particle physics and cosmic rays. In 1936, she was the only female to complete a M.Sc. degree at the University of Calcutta. After graduating, she joined the Bose Institute and together with Debendra Mohan Bose, discovered the boson subatomic particle. During her Ph.D. studies at the University of Manchester, Chowdhuri worked on cosmic rays and investigated air showers, which are cascades of ionized particles and electromagnetic radiation produced when a cosmic ray enters the atmosphere. She discovered that when particle density of an air shower increases, so does the density of penetrating events. A life-long researcher, Chowdhuri published her last paper a year before her death. For her contributions, the International Astronomical Union (IAU) named a star in the Sextans constellation “Bibha” in her honour.  

Roseli Ocampo-Friedmann

The microbiologist who studied life in extreme conditions

Roseli Ocampo-Friedmann (23 November 1937 – 4 September 2005) was a Filipino-American scientist whose research focused on cyanobacteria and microorganisms that inhabit extreme environments. Together with her husband Imre Friedmann, she travelled around the world to study algae and other microorganisms. One of the places they visited was the Ross Desert in the Dry Valleys region of Antarctica, which was thought to be lifeless as a result of a lack of snow and ice. However, the couple discovered microorganisms, known as cryptoendoliths, that could tolerate the cold and come back to life in the summer. Ocampo-Friedmann managed to culture these microorganisms in the laboratory and NASA recognized the research as supporting the theory that microscopic life could exist on Mars because it has similar environmental conditions as Antarctica. In her lifetime, Ocampo-Friedmann collected over 1,000 types of microorganisms from extreme environments worldwide.

Tsai-Fan Yu

The doctor who alleviated gout

Tsai-Fan Yu (1911 – 2 March 2007) was a Chinese-American physician and researcher who was the first female full professor at Mount Sinai School of Medicine. She discovered that gout, a condition characterized by the painful inflammation of joints, was caused by elevated levels of uric acid in the bloodstream. She also established a clinic at Mount Sinai to treat gout and tested drugs to treat the condition. Yu and her colleagues showed that probenecid, colchicine and allopurinol were effective at treating gout by increasing excretion of uric acid, reducing inflammation and preventing the formation of uric acid respectively. These drugs are still used to treat the condition today.     

Lin Lanying - The mother of aerospace and semiconductor materials

The mother of aerospace and semiconductor materials

Lin Lanying (7 February 1918 – 4 March 2003) was a Chinese material engineer remembered for her contributions to the field of semiconductor and aerospace materials. Lanying was born into a family who did not believe in educating girls and she was not allowed to go to school. Despite her family’s objections, Lin earned a Bachelor’s degree in Physics from Fukien Christian University. She earned another Bachelor’s degree in Mathematics from Dickinson College and received a PhD in solid-state physics at the University of Pennsylvania. Lin was the first in China to synthesize the crystals of several aerospace and semiconductor materials, including mono-crystalline germanium which led to the development of transistor radios. Her research laid the foundation for the development of micro-electronics and optoelectronics in China. For her contributions to the field, Lin was elected as an academician of the Chinese Academy of Sciences and became the vice president of the China Association for Science and Technology. Lin is known as the mother of aerospace and semiconductor materials in China.

Michiyo Tsujimura - The scientist who discovered Vitamin C in Green Tea

The scientist who discovered vitamin C in green tea

Michiyo Tsujimura (17 September 1888 – 1 June 1969) was a Japanese agricultural scientist and biochemist recognized for her research of green tea components. Together with her colleague Seitaro Miura, Tsujimura was the first to discover that green tea contains vitamin C while she was a student at the RIKEN research institute. This discovery led to an increase in the popularity of green tea and consequently, a boost in green tea export from Japan to North America in the early 1900s. Tsujimura also isolated and extracted catechin, tannin and gallocatechin, constituents with anticancer properties, from green tea. Her research earned her a PhD from the Tokyo Imperial University and Tsujimura became the first female doctor of agriculture in Japan. A dedicated teacher, Tsuijimura held professor and lecturer positions at Ochanomizu University and Jissen’s Women University, respectively. For her green tea research, she was awarded the Japan Prize of Agricultural Science in 1956 and conferred the Order of the Precious Crown of the Fourth Class in 1968.

Meemann Chang

The scientist who studied fish fossils

Meemann Chang (born 17 April 1936) is a Chinese palaeontologist who studied the fossils of ancient fish to understand the evolution of life. By examining fossils, she uncovered new insights on how vertebrates, animals with a backbone, migrated from the sea and became adapted to live on land. Chang was named the 2018 L'Oréal-UNESCO For Women in Science Awards laureate for her work determining that lobe-finned fish – not lungfish as previously thought – were the evolutionary link between marine life and mammals. In the same year, she received the Ho Leung Ho Lee Foundation Achievement Prize, which recognizes the accomplishments of Chinese scientists. Several species have been named in her honour, including the extinct fish Meemannia, the extinct bird Archaeornithura meemannae and the dinosaur Sinovenator changii. Even a unique organ of armoured prehistoric fish, consisting of an internal cavity with an external opening, was named “Chang’s Apparatus” after her. In 1983, Chang became the first female to head the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) in China.

Aditi Pant

The first woman from India to visit Antarctica

Aditi Pant was an oceanographer who was the first woman from India to visit Antarctica as part of the Indian Antarctic Program. Conversations with her parents and outdoor activities sparked Pant’s interest in science and the natural world. Pant was inspired to become an oceanographer after reading the book “The Open Sea,” which described the life of plankton. Her research focused on marine plankton communities and subsequently, salt-tolerant and salt-loving microorganisms involved in oceanic food chains. After India signed the Antarctic Treaty in 1981, Aditi Pant went on the third and fifth expeditions to Antarctica to gather information on food chain physics, chemistry and biology in the Antarctic Ocean. During the third mission, the team also constructed Dakshin Gangotri, the first Indian scientific research base station at Antarctica.

Rampa Rattanarithikul

The mosquito expert who established a museum of insects and natural wonders  

Rampa Rattanarithikul is a Thai entomologist who is a leading expert on mosquitoes. Rattanarithikul began her scientific career as a technician collecting mosquito specimens for the United States Operations Mission (USOM) malaria control program. Throughout her career, she discovered 23 species and officially described 13 others. Two species are named after her: Anopheles rampae and Uranotaenia rampae. With encouragement from the Walter Reed Army Institute of Research (WRAIR), she developed illustrated guides to the mosquitoes of Thailand. In 2011, Rattanarithikul received the American Mosquito Control Association's John N. Belkin Memorial Award in recognition of her contributions to mosquito biology. Rattanarithikul and her husband established the Museum of World Insects and Natural Wonders in Chiang Mai to share their passion for the natural world and raise awareness for the importance of conservation. On display are insect species, stones, petrified wood, fossils and wood carvings that the couple have collected.

Rajeshwari Chatterjee

The engineer who researched microwaves

Rajeshwari Chatterjee (24 January 1922 – 3 September 2010) was the first female engineer from Karnataka in India. Chatterjee earned a Master’s degree and doctoral degree from the University of Michigan on a scholarship awarded by the Delhi government. When Chatterjee returned to India, she became a faculty member at the Indian Institute of Science’s Department of Electrical Communication Engineering, where she taught electromagnetic theory, electron tube circuits, microwave technology and radio engineering. Chatterjee and her husband set up the first microwave engineering research laboratory in India. In her career, she wrote over 100 research papers and authored seven books. For her contributions to microwave engineering, Chatterjee won many notable awards, including the J.C Bose Memorial prize for the best research paper from the Institution of Engineers and the Ramlal Wadhwa Award for the best research and teaching work from the Institute of Electronics and Telecommunication Engineers. Her contributions to microwave research and antennae engineering are used in the field of radar and aircraft and spacecraft applications. Chatterjee was also interested in societal issues and after retiring from research, worked with social programs to address issues on caste segregation, gender discrimination and poverty.

Chien-Shiung Wu

The physicist who measured radioactive decay

Chien-Shiung Wu (31 May 1912 – 16 February 1997) was an experimental physicist who made several important contributions to nuclear physics. Wu worked on the Manhattan Project – a top-secret program for the production of nuclear weapons during World War II and helped to develop a process for separating uranium into U235 and U238. She also developed improved Geiger counters to measure nuclear radiation levels. At the time, it was believed that symmetry governed everything in nature – known as the law of Conservation of Parity. Among her contributions, Wu is best known for designing the Wu experiment in which she measured the decay of supercooled radioactive cobalt to investigate if symmetry was also conserved in the behaviour of atomic particles. Her findings showed that symmetry during the decay of atomic particles was not conserved, contradicting the law of Conservation of Parity. In 1978, Wu was awarded the inaugural Wolf Prize, a prestigious award which recognizes achievements in the interest of mankind and friendly relations among people ... irrespective of nationality, race, colour, religion, sex or political views." For her research on radioactivity, Wu is often referred to as the "Chinese Marie Curie".

Kono Yasui

The botanist who overcame the odds

Kono Yasui (16 February 1880 – 24 March 1971) was a Japanese botanist who researched the genetics of poppies, corn and spiderworts and surveyed the plants that had been affected by the nuclear fallout after the atomic bombings of Hiroshima and Nagasaki. A pioneer in many ways, Yasui was the first Japanese woman to receive a doctoral degree in science and also the first Japanese woman to publish in an international journal. In 1929, Yasui founded the cytology journal Cytologia. Growing up, Yasui’s family encouraged her to pursue her passions, even if they conflicted with gender norms of the time. The Japanese government initially rejected her application to study in America on the belief that “a woman cannot achieve much in science.” She was only allowed to study overseas on the condition that she listed “home economics research” alongside “scientific research” as her areas of study and that she agreed not to marry. After she returned to Japan, Tokyo Imperial University awarded her a doctoral degree in science for her research on how plants turned into coal, even though she was not an official student. After World War II, Yasui played a pivotal role in the transformation of Tokyo Women’s Higher Normal School into a comprehensive university for women, renamed Ochanomizu University. Together with fellow scientist Chika Kuroda, she established the Yasui-Kuroda Scholarship to provide educational opportunities for young female researchers.

Susan Lim

The parasitologist who studied flatworms

Susan Lim (14 February 1952 – 2 August 2014) was a Malaysian parasitologist who specialized in studying a class of flatworms, the Monogeans, which are parasites of fishes. Monogean flatworms are of significant economic importance as they can severely affect fishes reared on farms for food. Lim described more than 100 new species of monogeans and discovered a new attachment mechanism. Lim became the sixth most productive monogean researcher and the most prolific female one. She was also the first and only Malaysian elected to the International Commission on Zoological Nomenclature. Four monogean flatworm species are named in her honour.

Kimishige and Teruko Ishizaka

The immunologists who studied allergic reactions

Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions. A pioneer of her time, Teruko earned a M.D. and Ph.D. in medical science from the Tokyo’s Women’s Medical University and from the University of Tokyo respectively. Teruko was the head of the Division of Allergy at the La Jolla Institute for Immunology, while Kimishige was the first scientific director of the institute. The Ishizakas supported young scientists and encouraged a collaborative spirit among the researchers at the institute. On retirement, the couple moved to Teruko’s hometown, Yamagata, Japan, where Kimishige was a specially invited professor at Yamagata University. Throughout their careers, the duo co-authored over 100 papers and reviews on allergy-related topics and won several awards. (Photo courtesy of Yamagata University, Faculty of Medicine)

Janaki

The botanist who sweetened sugarcane

Janaki Ammal Edavalath Kakkat (4 November 1897 – 7 February 1984) was an Indian botanist who studied plant chromosomes and genetics. When she was a child. Kakkat’s parents encouraged her intellectual pursuits. After several teaching stints in India and US, Kakkat received a fellowship to pursue a Doctor of Science in botany in the US, becoming one of the few Asian women to be conferred a D.Sc. by the University of Michigan. Her research on chromosome numbers in plants was vital in the selection of varieties for cross-breeding to produce sweeter sugarcane. Kakkat created a high-yielding variety of sugarcane, a new variety of eggplant named Janaki Brengal, and a variety of magnolias named Magnolia Kobus Janaki Ammal.

Maryam

The mathematician who drew doodles 

Mathematician Maryam Mirzakhani (12 May 1977 – 14 July 2017) was the first and only woman and Iranian to date to win the Fields Medal in 2014 for her work on curved surfaces. She liked to focus on particularly difficult areas of theoretical mathematics and geometry, and in her short life, made several important contributions to understanding mathematical objects called Riemann surfaces. Describing herself as a “slow” mathematician who appreciated the beauty in mathematics, Mirzakhani often drew doodles on sheets of paper and wrote mathematical formulas around the drawings.

Okazaki

The couple who primed DNA replication

Tsuneko (7 June 1933) and Reiji Okazaki (8 October 1930 – 1 August 1975) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand. The couple met in Nagoya University and after obtaining PhDs, started a laboratory to conduct research on DNA replication. Funds were tight and the Okazakis often had to pay for research supplies themselves. After Reiji’s death from leukemia at the age of 44 from radiation exposure during the dropping of the atomic bomb on Hiroshima in World War II, Tsuneko continued their work, while raising their two children. At the time, female scientists were not recognized as full-fledged researchers in Japan and Tsuneko was encouraged to give up research to raise her young family. With support from the scientific community and a neighbour who helped care for her children, Tsuneko discovered that Okazaki fragments were the starting points of DNA replication. Since then, she has received multiple honours and awards, including the L’Oreal-UNESCO Award for Women in Science in 2000. Tsuneko has advocated for better support for women in science and lower education costs.

Kuroda

The chemist who studied the structures of pigments

Chika Kuroda (24 March 1884 – 8 November 1968) was a Japanese chemist whose research focussed on the structures of natural pigments. Kuroda determined the molecular structure of shikonin, the pigment in purple gromwell (Lithospermum erythrorhizon) as well as the structure of carthamin, the red pigment in safflower (Carthamus tinctorius). Her extraction of quercetin crystals from onion skin led to the development of the antihypertensive drug Kerutin C. Kuroda was a pioneer in many ways. She was amongst the first female students to be admitted to Tohoku Imperial University when it started accepting females and became the first woman in Japan to receive a Bachelor of Science. Kuroda was also the second woman in Japan to receive a doctorate in Science.

Asima

A woman ahead of her time

Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids. Growing up, she shared her father’s interest in botany and pursued higher education during a period when it was unusual for women to attend university. In 1944, she became the first woman in India to be awarded a Doctor of Science. Chatterjee’s research led to the development of an anti-epileptic drug, Ayush-56, as well as several antimalarial drugs. A prolific scientist, Chatterjee published approximately 400 papers in national and international journals.

An educator for life

Chinese physicist Xie Xide (19 March 1921 – 4 March 2000) was an influential educator and one of China’s pioneer researchers of solid-state physics. A promising student, Xie was awarded a scholarship to pursue a master’s degree in physics at Smith College in the United States, and earned a PhD in theoretical physics from the Massachusetts Institute of Technology. Returning to China, she taught in Fudan University’s physics department from 1952 to 1956. Despite later undergoing several major surgeries, Xie continued teaching and tirelessly championed science. Her book Semiconductor Physics became one of China’s most widely used physics textbooks. In 1977, Xie founded the Fudan Institute of Modern Physics, and served as its director from 1978 to 1983. She also established eight research laboratories in surface physics. As President of Fudan University, Xie encouraged teachers and students to study abroad and trained several scientists in the semiconductor field. “As long as my heart is still beating, I will always fight for the progress of science,” Xie said. An educator until the end, she donated her body to scientific research after her death. (Photo courtesy of Fudan University)

The chemist dedicated to education

Eminent Filipina scientist and educator Clara Lim-Sylianco (18 August 1925 – 23 July 2013) is remembered for her extensive research on mutagens – often-carcinogenic agents that permanently alter genetic materials such as DNA – antimutagens and bioorganic mechanisms. She also wrote many chemistry textbooks, some of which remain in use today. Drawing on both organic chemistry and biochemistry, Lim-Sylianco’s research advanced the understanding of specific areas of study including environmental mutagens and the mutagenicity of medical plants found in the Philippines. She published over 50 scientific articles, seven books and five monographs on research encompassing organic chemistry, biochemistry, genetic toxicology and molecular nutrition. In 1958, Lim-Sylianco became a Fellow of the Royal Society and in 1977 she received the Philippine Association for the Advancement of Science and Technology’s Gregorio Y. Zara Award. Lim-Sylianco was also recognised as a National Scientist of the Philippines, the highest award accorded to Filipino scientists by the Philippine government.

The biochemist who paved the way for India’s female researchers

In 1939, biochemist Kamala Sohonie (18 June 1911 – 28 June 1998) became the first woman to be accepted into the Indian Institute of Science (IISc). Born in Indore, Madhya Pradesh to a family of distinguished chemists, Sohonie wanted to follow in her father’s and uncle’s professional footsteps. Although she topped her class at university, her research fellowship application to IISc was rejected by the institute’s director, who believed women were not sufficiently competent to conduct research. Determined to continue her studies, Sohonie staged a peaceful protest and the director, C.V. Raman, agreed to accept her into the institution. But there were several conditions attached: Sohonie would be on probation for a year until Raman deemed her work worthy; she would work whenever her mentor required her to, irrespective of time of day; and she would not be a “distraction” to male researchers. Sohonie was the first scientist to characterise the proteins in pulses, a type of legume commonly eaten in India. Her research impressed Raman so much that he began accepting women into the program. In 1937, Sohonie received a research scholarship to complete her Ph.D. at the University of Cambridge, where she discovered cytochrome C, an enzyme important for energy generation, found in all plant cells. When she returned to India, Sohonie studied the effects of vitamins and how to accurately quantify vitamin content in foods. She and her students also examined the nutritional value of foods commonly eaten by India’s poorest citizens. Sohonie discovered that an inexpensive dietary supplement, palm nectar-- also known as Neera-- significantly improved the health of malnourished children and pregnant women. Sohonie passed away in 1998, shortly after having been honoured by the Indian Council of Medical Research.

The angel of Santo Tomas

Fe Villanueva del Mundo (27 November 1911 – 6 August 2011) was a Filipina paediatrician who founded the Philippines’ first paediatric hospital. The death of her older sister, who had wanted to become a doctor, spurred del Mundo to become a physician. She graduated top of her class at the University of the Philippines, and in 1936 became the first female student to attend Harvard Medical School. Returning to the Philippines during World War II and volunteering for the International Red Cross, del Mundo cared for children of foreigners in an internment camp at the University of Santo Tomas, earning her the name “The Angel of Santo Tomas”. Frustrated by the scarcity of hospital beds while running a government-funded children’s hospital, she sold her home and possessions to build the first children’s hospital in the Philippines, the Children’s Medical Center in Quezon City. In a career spanning eighty years until her death a few months short of 100 years old, del Mundo brought healthcare services to rural regions of the Philippines. She invented an incubator made from bamboo to keep infants warm in villages lacking electrical power.

Fighting for her country and against hunger

Filipina chemist María Orosa (29 November 1892–13 February 1945) fought malnutrition and food insecurity in the Philippines by devising over 700 culinary creations including Soyalac, a nutrient rich drink made from soybeans, and Darak, rice cookies packed with Vitamin B1, which could prevent beriberi disease caused by Vitamin B1 deficiency. She was also a partisan of the guerrilla movement resisting Japanese occupation during World War II, and died after being struck by shrapnel while working in her laboratory during the Battle of Manila. Orosa completed her Bachelor’s and Master’s degrees in pharmaceutical chemistry, along with a Bachelor’s degree in food chemistry, at the University of Washington. In addition to putting her training to work by creating enriched foods, she also invented an iconic banana ketchup made from banana, sugar, vinegar and spices. During World War II, she devised a process for canning food, which helped the Philippines become self-sufficient. Her multiple food innovations reduced the reliance of the Philippines on foreign imports and helped to save the lives of thousands of Filipinos during the war. ( Photo courtesy of the Orosa family)

The physicist who built her career on clay

Purnima Sinha (12 October 1927 – 11 July 2015), the first Bengali woman to receive a doctorate in physics, analysed clay structures using x-ray equipment that she built from salvaged World War II-era parts. Her later work at Stanford University’s 'Origin of Life' project uncovered a connection between the X-ray structure of clay and the patterns in DNA. Growing up in a progressive family that rejected the strictly-defined female roles of the day enabled Sinha and her sisters to pursue their interests in science.  Sinha earned a Master’s degree in Physics from Calcutta University, where her passion for the subject caught the attention of Satyendra Nath Bose, best known for his research on quantum mechanics in the 1920s. Bose suggested that Sinha’s doctoral work should examine the structure of clay from different parts of India, using techniques such as thermal and chemical analysis and X-ray scattering. Her subsequent efforts led to a complete classification of more than fifty clay samples. Outside the laboratory, Sinha translated science books into Bengali. She was also a talented musician who played the tabla, a percussion instrument usually played by men.

Exploring the medicinal potential of native plants

The research of Filipino pharmaceutical chemist Luz Oliveros-Belardo (3 November 1906 – 12 December 1999) focussed on essential oils and other chemicals derived from native Philippine plants. In a career that spanned five decades, Oliveros-Belardo extracted 33 new essential oils for use in pharmaceuticals, in food production, as scents, and in other applications. She found that compounds in lemongrass such as potassium citrate may be effective at treating high blood pressure. She also investigated the anti-cancer properties of the alkaloids, glycosides, terpenoids, sterols, fatty acids, and volatile oil extracted from the periwinkle plant. Oleoresin, extracted from Apitong, a tree commonly used to make charcoal, paper pulp, and timber in Southeast Asia, was used by Oliveras Belardo as a component in motor fuel. For her extensive research on herbal medicine and plant extracts, Oliveros-Belardo was recognised as a National Scientist of the Philippines in 1987, the highest award accorded to Filipino scientists by the Philippine government. (Photo courtesy of The National Academy of Science and Technology)

Uncovering the link between viruses and cancer

Ground-breaking cancer researcher Kamal Jayasing Ranadive (8 November 1917 – 11 April 2001)   advanced the understanding of the causes of leukaemia, breast cancer and oesophageal cancer through the use of animal models. She was also among the first to recognise how susceptibility to cancer is linked to tumour-causing interactions between hormones and viruses. Trained as a botanist, before turning her attention to tissue culture, Ranadive returned to India after a postdoctoral stint at Johns Hopkins University Hospital. Back in her homeland, she established the country’s first tissue culture laboratory at the Indian Cancer Research Centre. The lab’s renown in the field was due, in part, to Ranadive’s talent for recognising scientific talent and her efforts to encourage researchers to work in various areas of cancer biology. Ranadive also contributed to the development of a leprosy vaccine through her research into the leprosy-causing Mycobacterium leprae bacterium. With the goal of promoting public knowledge of science, especially among women and children, she founded the Indian Women Scientists’ Association (IWSA). After retirement, Ranadive worked to improve the health of women and children in Maharashtra’s rural communities by providing health and nutrition education, and by training women as healthcare workers.

Rock researcher wrote the first Chinese palaeontology textbooks

Palaeontologist Yichun Hao (1920 – 2001) co-authored the first Chinese textbooks on palaeontology and micropalaeontology. Her research on Foraminifera – amoeba-like organisms with shells – was vital for the exploration and utilisation of marine energy resources. Hao also made significant contributions to the fields of stratigraphy and palaeontology, petroleum exploration and palaeoceanography. Together with her research team, she mapped the rock layers in the northeast and southwest regions of China. Hao’s academic positions included serving as vice-president of the Palaeontological Society of China, as president of the Micropalaeontological Society of China, and as a member of the International Science Union. In 1980, she became an academician in the Academic Division of Earth Sciences of the Chinese Academy of Sciences.

A fiercely independent organic chemist

A pioneer of bio-organic chemistry, Darshan Ranganathan (4 June 1941 – 4 June 2001) is remembered for developing a protocol for synthesising imidazole, a compound used to make antifungal drugs and antibiotics. Widely considered India’s most prolific researcher in chemistry, she also published dozens of papers in renowned journals on protein folding, molecular design, chemical simulation of key biological processes, and the synthesis of functional hybrid peptides and nanotubes. Educated in Delhi, Ranganathan’s career moved into high gear when she received a research fellowship from the Royal Commission for the Exhibition of 1851, which enabled her to conduct postdoctoral research on organic natural products at Imperial College London. There, she studied compounds such as cycloartenol, a type of plant sterol found in jackfruit. Since jackfruits weren’t available in England, Ranganathan enlisted her mother’s help to ship them from India.  Independent and strong-willed, Ranganathan was undeterred when, upon her return to India, she was denied faculty status in the same university department as her husband, owing to administrators’ concerns over conflict of interest. In response, Ranganathan funded her entire research career through multiple independent fellowships, a strategy which enabled the couple to publish several books on organic chemistry together. Ranganathan became a Fellow of the Indian Academy of Sciences. She also won the A.V. Rama Rao Foundation Award, the Jawaharlal Nehru Birth Centenary Visiting Fellowship, Third World Academy of Sciences Award in Chemistry, and the Sukh Dev Endowment Lectureship.

 

 


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