Medicine & Healthcare Dermatology

News

29 Jun 2022
The skin’s top layer contains a diverse set of hundreds of lipid molecules called ceramides with varying chain lengths that play a vital role in its barrier function.
23 Dec 2021
By searching for the protein transglutaminase 1 (TGM1) among patients with various autoimmune skin diseases, researchers have successfully identified a separate disease that can be linked to autoimmunity against TGM1. This backward method demonstrates a new way of identifying autoantigens as markers for various diseases. By letting autoantigens point to the disease, diagnosis and treatment can be facilitated, according to the study now published in PNAS.
27 Oct 2021
Researchers reveal correlation between ribotype (RT) strains of Cutibacterium acnes, which are found in human skin, and the lifespan of the nematode Caenorhabditis elegans. Strains RT4 and 8, which are associated with acne in human skin, shortened the lifespan of the nematode, while RT6, which are predominantly found in healthy human skin, did not. Also, it was found that the healthy skin-related RT6 strain of C. acnes improved C. elegans resistance to the pathogenic organism Staphylococcus aureus.
A fluorescent micrograph of a cross-section through an epidermal blister on mice skin
14 Jun 2021
A team of scientists has shown that the healing of skin blisters is driven by hair follicle stem cells, which delay their own development in the process.
25 Mar 2021
Through a series of experiments using nasal polyp organ culture and mouse models of restraint stress, researchers unveil relationship between presence of corticotropin-releasing stress hormone and increase in and degranulation of allergy-causing mast cells.
20 Feb 2020
A faculty startup, based at South Korea's Ulsan National Institute of Science and Technology (UNIST) has attracted 7 Billion KRW investment.
22 Jan 2018
A new method for controlling pigmentation in fabricated human skin has been developed by researchers from A*STAR’s Singapore Institute of Manufacturing Technology (SIMTech) and the Singapore Centre for 3D Printing (SC3DP) at Nanyang Technological University.
Non-inflammatory bullous pemphigoid (BP) seen in the type 2 diabetes patient who are administered with DPP-4 inhibitor.
06 Dec 2017
Researchers have identified a type of human leukocyte antigen (HLA) that is associated with the skin disease bullous pemphigoid (BP) in diabetic patients administered with DPP-4 inhibitory drugs.
Diagram explaining the concept of autoinflammatory keratinization diseases (AIKD)
13 Jul 2017
Nagoya University-led team reviews skin diseases to define a new type of genetic-based inflammation for improving diagnosis and treatment of rare skin conditions.
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07 Jul 2017
Type XVII collagen (COL17) is found to regulate the proliferation of epidermal cells and therefore the thickness of juvenile and aged skin, suggesting COL17 can potentially be used for future anti-aging strategies.
Gonadal Mosaicism Can Cause Whole-Body Birthmarks
16 Jun 2017
A Nagoya University research collaboration reveals the father–daughter inheritance of a mosaic skin disease as a sperm cell mutation causing a whole-body skin disorder: relevance to genetic counseling.
06 Jun 2017
Scientists in South Korea have come up with a new method for 3D printing human skin, which both shortens the process and reduces the cost.

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Researchers

Takashi Hashimoto's major expertise is clinical and basic research for both autoimmune bullous diseases and hereditary skin diseases.