NATURE AND THE NATURE RESEARCH JOURNALS PRESS RELEASE
For papers that will be published online on 19 August 2007
This press release is copyrighted to the Nature journals mentioned below.
This press release contains:
· Summaries of newsworthy papers:
Getting on worms’ nerves – Nature Methods
· Mention of papers to be published at the same time with the same embargo
· Geographical listing of authors
PDFs of all the papers mentioned on this release can be found in the relevant journal’s section of http://press.nature.com. Press contacts for the Nature journals are listed at the end of this release.
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PLEASE CITE THE SPECIFIC NATURE JOURNAL AND WEBSITE AS THE SOURCE OF THE FOLLOWING ITEMS. IF PUBLISHING ONLINE, PLEASE CARRY A HYPERLINK TO THE APPROPRIATE JOURNAL’S WEBSITE.
********************************************NATURE METHODS******************************************
[1] Getting on worms’ nerves
DOI: 10.1038/nmeth1075
Two devices that help researchers correlate nerve cell activity with behaviour in the living worm are presented in Nature Methods this week.
The microscopic worm C. elegans has a very simple nervous system, with only 302 neurons. However, it is difficult to monitor neuronal activity in worms without either using invasive methods or restraining them in an unphysiological way. Nikos Chronis and colleagues present devices which make it possible to use a microscope to monitor nerve activity in intact, live worms. The key is that the worms are enclosed in tiny channels only slightly bigger than the animals, so that they are free to move to some extent, but restrained sufficiently to allow for imaging of the neurons. The trapped worms can also be stimulated in a very controlled fashion by substances delivered at the tip of the animal’s nose, so that their effect on nerve activity can be recorded.
The researchers used these devices to uncover new information about particular neurons involved in movement and sensation in the worm. This may very well pave the way to ever more sophisticated devices, as well as to devices for monitoring other small organisms in physiological and precisely controlled environments.
Author contact:
Nikos Chronis (University of Michigan, Ann Arbor, MI, USA)
Tel: +1 734 763 0154; E-mail: [email protected]
Other papers from Nature Methods to be published online at the same time and with the same embargo:
[2] Highly efficient and sensitive identification of somatic mutations in lung tumors using E. coli mismatch repair detection
DOI: 10.1038/nmeth1081
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Items from other Nature journals to be published online at the same time and with the same embargo:
Nature (http://www.nature.com/nature)
[3] Mechanism of chloride interaction with neurotransmitter:sodium symporters
DOI: 10.1038/nature 06133
[4] ZEITLUPE is a circadian photoreceptor stabilized by GIGANTEA in blue light
DOI: 10.1038/nature06132
[5] Enzymatic capture of an extrahelical thymine in the search for uracil in DNA
DOI: 10.1038/nature06131
NATURE PHOTONICS (http://www.nature.com/nphoton)
[6] All-dielectric photonic-assisted radio front-end technology
DOI: 10.1038/nphoton.2007.145
[7] All-optical anatomical co-registration for molecular imaging of small animals using dynamic contrast
DOI: 10.1038/nphoton.2007.146
NATURE CHEMICAL BIOLOGY (http://www.nature.com/nchembio)
[8] A new family of ATP-dependent oligomerization-macrocyclization biocatalysts
DOI: 10.1038/nchembio.2007.23
Nature PHYSICS (http://www.nature.com/naturephysics)
[9] A Kapitza–Dirac–Talbot–Lau interferometer for highly polarizable molecules
DOI: 10.1038/nphys701
[10] Entangling independent photons by time measurement
DOI: 10.1038/nphys700
NATURE MATERIALS (http://www.nature.com/naturematerials)
[11] In vivo imaging of hydrogen peroxide with chemiluminescent nanoparticles
DOI: 10.1038/nmat1983
[12] Tensile ductility and necking of metallic glass
DOI: 10.1038/nmat1984
[13] Tailoring properties and functionalities of metal nanoparticles through crystallinity engineering
DOI: 10.1038/nmat1982
NATURE NANOTECHNOLOGY (http://www.nature.com/nnano)
[14] Multiscale patterning of plasmonic metamaterials
DOI: 10.1038/nnano.2007.252
[15] Highly efficient resonant coupling of optical excitations in hybrid organic/inorganic semiconductor nanostructures
DOI: 10.1038/nnano.2007.253
Nature MEDICINE (http://www.nature.com/naturemedicine)
[16] Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
DOI: 10.1038/nm1622
[17] Lack of Fas antagonism by Met in human fatty liver disease
DOI: 10.1038/nm1625
[18] CD8+ T lymphocytes protective against malaria liver stages are primed in skin-draining lymph nodes
DOI: 10.1038/nm1628
Nature BIOTECHNOLOGY (http://www.nature.com/naturebiotechnology)
[19] Comparative analysis of the complete genome sequence of the plant growth–promoting bacterium Bacillus amyloliquefaciens FZB42
DOI: 10.1038/nbt1325
[20] High-frequency generation of viable mice from engineered bi-maternal embryos
DOI: 10.1038/nbt1331
NATURE GENETICS (http://www.nature.com/naturegenetics)
[21] Discovery of a previously unrecognized microdeletion syndrome of 16p11.2–p12.2
DOI: 10.1038/ng2107
[22] Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation
DOI: 10.1038/ng2100
[23] Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1–like phenotype
DOI: 10.1038/ng2113
Nature NEUROSCIENCE (http://www.nature.com/natureneuroscience)
[24] A functional circuitry for edge-induced brightness perception
DOI: 10.1038/nn1948
[25] Nicotinic control of axon excitability regulates thalamocortical transmission
DOI: 10.1038/nn1956
NATURE CELL BIOLOGY (http://www.nature.com/naturecellbiology)
[26] Toll-like receptors modulate adult hippocampal neurogenesis
DOI: 10.1038/ncb1629
[27] S-nitrosylation of microtubule-associated protein 1B mediates nitric-oxide-induced axon retraction
DOI: 10.1038/ncb1625
[28] Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic
DOI: 10.1038/ncb1627
[29] The F-box protein Fbl10 is a novel transcriptional repressor of c-Jun
DOI: 10.1038/ncb1628
Nature STRUCTURAL & MOLECULAR BIOLOGY (http://www.nature.com/natstructmolbiol)
[30] Molecular basis of messenger RNA recognition by the specific bacterial repressing clamp RsmA/CsrA
DOI: 10.1038/nsmb1285
[31] An iron-sulfur domain of the eukaryotic primase is essential for RNA primer synthesis
DOI: 10.1038/nsmb1288
[32] Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression
DOI: 10.1038/nsmb1290
[33] Crystal structure of human DGCR8 core
DOI: 10.1038/nsmb1294
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GEOGRAPHICAL LISTING OF AUTHORS
The following list of places refers to the whereabouts of authors on the papers numbered in this release. The listing may be for an author's main affiliation, or for a place where they are working temporarily. Please see the PDF of the paper for full details.
AUSTRALIA
Adelaide: 22
Waratah: 22
AUSTRIA
Vienna: 9, 27
BELGIUM
Ghent: 23
Leuven: 23
CHINA
Harbin: 20
Shenyang: 12
FRANCE
Orleans: 16
Orsay: 9
Paris: 16, 23. 27
Villejuif: 16
GERMANY
Berlin: 19
Freiburg: 19
Gottingen: 19
Greifswald: 19
Karlsruhe: 9
Kiel: 16
Mainz: 9
Munich: 9
Tubingen: 9
ISRAEL
Jerusalem: 3
Rehovot: 26
ITALY
Naples: 16
JAPAN
Fukuoka: 23
Tokyo: 20
KOREA
Jinju: 4
Kyungbuk: 4, 33
Seoul : 33
MEXICO
Cuernavaca: 8
NEW ZEALAND
Auckland: 4
POLAND
Gdansk: 23
SOUTH AFRICA
Pretoria: 19
SWITZERLAND
Basel: 9
Geneva: 10
Lausanne: 30
Zurich: 30
TAIWAN
Taipei: 24
UNITED KINGDOM
Cambridge: 20, 22, 31
Coventry: 8
Edinburgh: 22
UNITED STATES OF AMERICA
Alabama
Birmingham: 23
Arizona
Tucson: 28
California
Berkeley: 16
Irvine: 25
Los Angeles: 6, 21
San Francisco: 2
Georgia
Atlanta: 11
Decatur: 11
Illinois
Evanston: 14
Rockford: 22
Kentucky
Louisville: 21
Louisiana
Baton Rouge: 22
Maryland
Baltimore: 5, 12, 18, 22
Bethesda: 23
College Park: 13
Massachusetts
Cambridge: 9, 15
Charlestown: 7
Michigan
Ann Arbor: 1
New Jersey
Piscataway: 28
New York
Manhasset: 16
New York: 1, 3, 7, 29
North Carolina
Chapel Hill: 32
Ohio
Columbus: 4
Pennsylvania
Philadelphia: 21
Pittsburgh: 17, 21
University Park:
Rhode Island
Providence: 15
South Carolina
Greenwood: 22
Tennessee
Nashville: 24
West Virginia
Morgantown: 24
Washington
Spokane: 21
Wisconsin
Madison: 21
PRESS CONTACTS…
For media inquiries relating to embargo policy for all the Nature Research Journals:
Katherine Anderson (Nature London)
Tel: +44 20 7843 4502; E-mail: [email protected]
Ruth Francis (Senior Press Officer, Nature, London)
Tel: +44 20 7843 4562; E-mail: [email protected]
For media inquiries relating to editorial content/policy for the Nature Research Journals, please contact the journals individually:
Nature Biotechnology (New York)
Peter Hare
Tel: +1 212 726 9284; E-mail: [email protected]
Nature Cell Biology (London)
Bernd Pulverer
Tel: +44 20 7843 4892; E-mail: [email protected]
Nature Chemical Biology (Boston)
Andrea Garvey
Tel: +1 617 475 9241, E-mail: [email protected]
Nature Genetics (New York)
Orli Bahcall
Tel: +1 212 726 9311; E-mail: [email protected]
Nature Materials (London)
Fabio Pulizzi
Tel: +44 20 7014 4024; E-mail: [email protected]
Nature Medicine (New York)
Juan Carlos Lopez
Tel: +1 212 726 9325; E-mail: [email protected]
Nature Methods (New York)
Allison Doerr
Tel: +1 212 726 9393; E-mail: [email protected]
Nature Nanotechnology (London)
Peter Rodgers
Tel: +44 20 7014 4019; Email: [email protected]
Nature Neuroscience (New York)
Sandra Aamodt (based in California)
Tel: +1 530 795 3256; E-mail: [email protected]
Nature Photonics (Tokyo))
Oliver Graydon
Tel: +81 3 3267 8776; E-mail: [email protected]
Nature Physics (London)
Alison Wright
Tel: +44 20 7843 4555; E-mail: [email protected]
Nature Structural & Molecular Biology (New York)
Michelle Montoya
Tel: +1 212 726 9326; E-mail: [email protected]
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