Nature’s newsmaker of the year: Lyn Evans and Nature Methods: Method of the Year

The person who did more than any other to build the world's newest and most powerful particle accelerator is named as Nature's newsmaker of 2008 and Super-resolution fluorescence microscopy has revolutionized the field of molecular and cell biology.

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Nature’s newsmaker of the year: Lyn Evans

Each year the journal Nature acknowledges a Newsmaker of the Year to celebrate the role that individuals have in science, and in particular in public discussion about science. The person who did more than any other to build the world's newest and most powerful particle accelerator is named as Nature's newsmaker of 2008.

For almost 15 years, Lyn Evans has worked as the project manager of the Large Hadron Collider (LHC), located at CERN, the European high-energy physics laboratory near Geneva, Switzerland. The LHC is a 3.8 billion Swiss franc (US$3.2 billion) machine that will accelerate protons to close to the speed of light and then collide them together in the hopes discovering new physics.

The 27-kilometre machine was completed this year, and successfully circulated its first protons in September, but was sidelined by a major accident shortly afterwards. Evans has been there every step of the way — from its design, to negotiations with CERN’s 20 member nations, through to the collider’s eventual completion. He has seen the project through ups and downs, including the latest meltdown, which has left the machine incapacitated until next summer.

Although his loose management style has occasionally led to problems, the retiring Welshman from Aberdare has been a steady guide for the LHC. His technical skill and political savvy have been vital to the collider's completion, and Nature is pleased to honour his achievement as the 2008 newsmaker of the year.

Nature Methods: Method of the Year

Super-resolution fluorescence microscopy has revolutionized the field of molecular and cell biology, emerging as a powerful tool for scientists to view the inside of living cells at an unprecedented resolution. A flurry of advances in this field in 2008 has led Nature Methods to name the technique ‘Method of the Year’, with a series of special features published online this week.

It has been accepted for more than a century that light microscopy cannot resolve structures closer together than the so-called ‘diffraction limit’. Beginning in the 1990s, this assumption began to be challenged, and this pioneering work has led recently to fluorescence microscopy methods that can be used to ‘break’ the diffraction barrier. This means that cellular structures can be imaged, in live cells, at unprecedented nanometer-scale resolution. These methods are now poised for widespread application to biology, with tremendous potential for deeper understanding at the subcellular and even the macromolecular scale.

A perspective article by Stefan Hell, one of the trailblazers of this field, outlines the principles of microscopy and the various fluorescence nanoscopy techniques that have developed from them. A Commentary by Jennifer Lippincott-Schwartz discusses the promise that these methods hold and limitations that must be considered when developing the tools for widespread applications in cell biology.

In addition, the package of online features contains a short movie about the method featuring some of the developers. The video will be here from 1800 London time on Wednesday 17 December: http://www.nature.com/nmeth/video/moy2008/index.html

There will also be a selection of ‘Methods to Watch’ – methods about to have a profound impact on their field, such as reprogramming somatic cells to pluripotency, and developments in the field of synthetic life.

Author contacts:
Stefan W. Hell (Max Planck Institute, Göttingen, Germany)
Tel: +49 551 201 2500; E-mail: [email protected]

Jennifer Lippincott-Schwartz (NICHD, NIH, Bethesda, Maryland, USA)
Tel: +1 301 402 1009; Email: [email protected]

Editorial contact:
Natalie de Souza (Nature Methods, New York)
Tel: +1 212 726-9652; E-mail: [email protected]

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Published: 17 Dec 2008

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