15 Mar 2022
A research group has revealed that amyloid-β (Aβ) detected in blood is secreted from peripheral tissues (pancreas, adipose tissue, skeletal muscle, liver, etc.) that are sensitive to glucose and insulin. Also, that Aβ secreted from peripheral tissues acts as a regulator on pancreatic β-cells to suppress insulin secretion. The results of this study indicate that blood Aβ levels fluctuate significantly with diet, and special care should be taken when using blood samples as a diagnostic marker for Alzheimer's disease, such as taking blood samples during fasting.
15 Sep 2021
Using the lamprey, researchers from Japan analyzed the photosensory mechanism of the pineal organ, also called the pineal gland, in non-mammalian vertebrates and discovered a novel mechanism of pineal color discrimination (two-cell system) in which two types of photoreceptor cells, each containing two different opsins, are used to detect color. This discovery may provide insight into the evolution of color detection in other animals, including color vision in humans.
13 Jul 2021
Researchers from Osaka City University show the benefits of mixing alginic acid with calcium phosphate cement (CPC), a common bone replacement material, with in vitro and in vivo studies. The biopolymer is shown to improve the setting time and compressive strength of CPC, as well as help it acquire porosity – which allows cells to enter the defected area and grow new bone.
10 Mar 2021
Researchers reveal the path of information received by the hippocampus. Using optogenetics during large-scale recordings of rat subiculum, they discovered that the subiculum distributes information from the hippocampus to 4 downstream regions of the brain. They observed that the theta and sharp-wave/ripples in the subiculum controlled information transmission with millisecond precision according to the target region. This provides the foundation for a comprehensive understanding of the hippocampal memory system.
04 Mar 2021
Collecting liver tissue from 22 postoperative patients with long-term post-Fontan surgery, researchers have found a specific liver fibrosis to develop from the sinusoidal region which is difficult to accurately assess by conventional examination methods (ultrasound elastography and blood tests).
04 Sep 2020
Pregnant mice fed diets high in omega-6 fats and low in omega-3 fats are shown in a new study to produce offspring whose brains had a higher level of dopamine-producing neurons—the neurological reward system. These mice went on to chase hyper-caloric diets, suggesting that the fats in a pregnant mother's diet may control the eating habits of her children, and potentially offering a new obesity-prevention strategy.
11 Aug 2020
Scientists from the Daegu Gyeongbuk Institute of Science and Technology, Republic of Korea, discover a new way to diagnose Alzheimer’s disease by analyzing the levels of specific proteins in nasal discharge. This simple and inexpensive method could help in timely diagnosis of Alzheimer’s disease, in order to start treatment as soon as possible, thus delaying disease progression.
06 Sep 2019
A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has identified the sleep-promoting effects of dietary threonine, as well as its neurobiological principle.
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