02 Nov 2021
Malfunctioning of the so-called Hippo signalling pathway within animal cells leads to irregular activity of proteins that regulate genes involved in cell proliferation. Researchers have identified a key step in the process of this aberration, opening the door to new therapeutics for cancers such as head-and-neck squamous cell carcinoma and lung adenocarcinoma.
08 Jul 2021
Molecular evolution of enzyme beyond recruit hypothesis ●First determination of crystal structures of aconitase X by X-ray crystallographic analysis ●Evidence of a common ancestor of aconitase superfamily, appearing before the previously proposed one ●Evolutional insight of requirement of complicated metabolic pathways in primordial cell
05 May 2021
Biodiversity is of crucial importance to the marine ecosystem. The prohibition of trawling activities in the Hong Kong marine environment for two and a half years has significantly improved biodiversity, an inter-university study led by City University of Hong Kong (CityU) has found. Research results showed that the trawl ban could restore and conserve biodiversity in tropical coastal waters.
04 Dec 2020
Turning off gene-editing until it reaches cell cycle phases where more accurate repairs are likely to happen offers a promising fix to CRISPR-Cas9’s problem with unwanted genetic changes.
20 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has succeeded in unveiling the principle behind the changing sleep patterns, according to the ambient temperature, through the use of Drosophila as a model of sleep.
10 Nov 2020
Far too little is known about the long-term dynamics of the abundance of most macro-organism species. We used sedimentary DNA technology to quantify marine fish DNA abundance in sediment sequences spanning the last 300 years. This study first shows the existence of fish DNA in the sequences and proves that fish abundance can be tracked using sedimentary DNA, highlighting the utility of sedimentary DNA for researchers to acquire lengthy records of macro-organism species abundance.
29 Oct 2020
Scientists have revealed the molecular mechanism regulating the trafficking of lysosomes that increases the invasiveness of radioresistant cancer cells following radiotherapy.
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