Communications Biology

News

16 Nov 2022
Researchers from SANKEN (The Institute of Scientific and Industrial Research) at Osaka University have genetically engineered a protein to emit the shortest-wavelength fluorescence light reported to date. They did this by optimizing the interactions between the fluorescence center (chromophore) and its surroundings, in a manner that differs from previous reports. The resulting fluorescence emission was bright and stable over a useful range of pH values. This work will aid basic and applied research, such as understanding the behavior of healthy and diseased cells.
09 Aug 2022
Researchers at Kanazawa University report in Communications Biology that using common chemicals for fixing living cell samples for microscopy studies causes membrane proteins to aggregate.
Schematic of mechanistic mechanism by which EGFR activates YAP/TAZ
02 Nov 2021
Malfunctioning of the so-called Hippo signalling pathway within animal cells leads to irregular activity of proteins that regulate genes involved in cell proliferation. Researchers have identified a key step in the process of this aberration, opening the door to new therapeutics for cancers such as head-and-neck squamous cell carcinoma and lung adenocarcinoma.
Figure 1. Schematic reactions of aconitase superfamily members.
08 Jul 2021
Molecular evolution of enzyme beyond recruit hypothesis ●First determination of crystal structures of aconitase X by X-ray crystallographic analysis ●Evidence of a common ancestor of aconitase superfamily, appearing before the previously proposed one ●Evolutional insight of requirement of complicated metabolic pathways in primordial cell
05 May 2021
Biodiversity is of crucial importance to the marine ecosystem. The prohibition of trawling activities in the Hong Kong marine environment for two and a half years has significantly improved biodiversity, an inter-university study led by City University of Hong Kong (CityU) has found. Research results showed that the trawl ban could restore and conserve biodiversity in tropical coastal waters.
Turning off gene editing during error-prone cell cycle phases
04 Dec 2020
Turning off gene-editing until it reaches cell cycle phases where more accurate repairs are likely to happen offers a promising fix to CRISPR-Cas9’s problem with unwanted genetic changes.
20 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has succeeded in unveiling the principle behind the changing sleep patterns, according to the ambient temperature, through the use of Drosophila as a model of sleep.
Image for sedimentary DNA analysis
10 Nov 2020
Far too little is known about the long-term dynamics of the abundance of most macro-organism species. We used sedimentary DNA technology to quantify marine fish DNA abundance in sediment sequences spanning the last 300 years. This study first shows the existence of fish DNA in the sequences and proves that fish abundance can be tracked using sedimentary DNA, highlighting the utility of sedimentary DNA for researchers to acquire lengthy records of macro-organism species abundance.
Lysosomes in a breast cancer cell.
29 Oct 2020
Scientists have revealed the molecular mechanism regulating the trafficking of lysosomes that increases the invasiveness of radioresistant cancer cells following radiotherapy.

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