PloS One


10 Oct 2013
An automated assessment of multiple datasets using artificial intelligence accurately diagnoses a common cause of blindness
11 Sep 2013
Japanese researchers have identified a mutation associated with a higher incidence of lung cancer in Japanese women who do not smoke, but better survival in lung cancer patients.
25 Jun 2013
(Kanazawa, Japan, 25 June 2013)  Researchers at Kanazawa University Graduate School of Medical Science in Japan have determined how APOBEC proteins mediate hypermutations that inhibit viral replication. They also identify the host factor protein UNG that can repair these mutations.
08 Jan 2013
Shenzhen, China 8 Jan - Chinese researchers have solved the mystery of the function of sheaths in flowering orchids. In a paper published in PLOS ONE, the team led by Zhong-Jian Liu at the Orchid Conservation & Research Center of Shenzhen and Laiqiang Huang at Tsinghua University found the perch to be essential to orchid reproduction.
20 Sep 2012
(Okayama, Japan, 20 September 2012) - Okayama University researchers demonstrate that cancer stem cells can be produced from normal stem cells for new therapies to combat cancer
27 Aug 2012
(Tokyo, 27 August 2012) Tokyo Tech ‘s Yoshihiro Miyake and colleagues have developed an innovative, non-invasive therapeutic intervention that may improve the mobility, stability, and quality of life of Parkinson’s disease patients.
18 Jul 2012
New Pancreatic Cancer Animal Models to aid Novel Therapy Development. Austrianova Singapore announced today that they and their partners have created a mouse model that mimics human pancreatic cancer.
14 Jun 2012
A large-scale resource for investigating microbial communities throughout the human body and an analysis of these data is reported in two studies in this week’s Nature. Microbial communities that live on and in the human body, collectively known as the ‘microbiome’, are thought to have a critical role in human health and disease.
14 Mar 2012
Researchers at the RIKEN Omics Science Center (OSC) have successfully developed and demonstrated a new experimental technique for producing cells with specific functions. As an alternative to induced pluripotent stem cells, the technique promises to enable faster production of functional cells for use in cancer therapy and other areas.
12 Mar 2012
Mathematical Model Describes the Collaboration of Individual Neurons
Manual and automated processes
06 Feb 2012
Researchers at the RIKEN Omics Science Center (OSC) have developed a robotic workflow for sample preparation on the HeliScope single molecule sequencer which drastically reduces sample preparation time to from 42 days to only 8 days.
06 Feb 2012
A new diagnosis technique developed by researchers at the RIKEN Omics Science Center (OSC) has succeeded in detecting influenza virus infection in only 40 minutes and with one hundred times the sensitivity of conventional methods.
21 Nov 2011
Why don't woodpeckers injure themselves? Researchers at Hong Kong Polytechnic University and the Beihang University in Beijing have been investigating...
05 Aug 2011
A variant of a newly identified gene is linked to increased risk of developing osteoporosis in Japanese individuals
15 Jul 2011
A family tree of the 2009 pandemic influenza viruses in Japan reveals a high rate of viral evolution
Bioengineered tooth unit
12 Jul 2011
Collaborative research from the Tokyo University of Science shows potential for bioengineered mature organ replacement as a next generation regenerative therapy.
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13 May 2011
Assessing the chemical diversity of genetically modified organisms is an important first step for evaluating their safety
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12 May 2011
Researchers at the RIKEN Plant Science Center (PSC) have clarified a key epigenetic mechanism by which an enzyme in the model plant Arabidopsis protects cells from harmful DNA elements.
25 Apr 2011
Analysis of mutations of the 2009 pandemic influenza A(H1N1) virus by researchers at the RIKEN Omics Science Center (OSC) has revealed major genetic differences between the virus in its early phase of infection in Japan and in its peak phase.
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08 Apr 2011
Monkeys infected with an emerging malaria strain are providing a reservoir for human disease in South-east Asia, according to research published today.
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08 Mar 2011
Retinitis pigmentosa (RP) is a cluster of genetically determined eye disorders that cause visual defects such as night blindness and narrowing of the field of vision, due to progressive loss of rod photoreceptors. New work by Zi-Bing Jin and colleagues looks to add a set of powerful new tools for those searching for treatments for RP.
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03 Mar 2011
The rapid development of computational tools is shedding light on new genetic and molecular studies, but it is also creating headaches for the scientists involved in this research.
09 Sep 2010
Press Release - Reported in PLoS Computational Biology, the findings offer fundamental insights relevant to a wide range of biological, physical and technical systems.
18 Jun 2010
The discovery of novel risk factors for osteoarthritis illuminates a probable role for the immune system in the pathology of this joint disorder
07 May 2010
A large-scale genetic study reveals a novel risk factor for a potentially fatal kidney disorder associated with diabetes
19 Mar 2010
A ‘family’ tree of enzymes from protists in the termite gut may help boost biofuels research
26 Feb 2010
Characterization of changes acquired by gene pairs over time reveals principles underlying evolution of gene function
06 Jan 2010
A research team at RIKEN has clarified details of key mechanisms driving the emergence of functional novelty in genes of eukaryotes. In a paper to appear in PLoS Genetics, the researchers analyze the molecular-level mechanisms of functionalization in duplicate genes, shedding light on their relationship to morphological evolution.
13 Nov 2009
Experiments simulating zero-gravity conditions reveal developmental difficulties arising from mammalian reproduction in space
29 May 2009
A well-tuned sense of taste is about far more than being able to enjoy a fancy dinner—it represents a key survival mechanism, helping animals to rapidly identify potential food sources as tasty or toxic. A combination of computational and experimental techniques helps researchers to identify a gene involved in taste bud development


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