PloS One

Computational study carried out at Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences (Moscow) revealed energetically balanced reaction coordinate of the SpnF-catalyzed cycloaddition reaction leading to Spinosyn A – tetracyclic natural insecticide produced by the cells of the bacterium Saccharopolyspora spinosa.

Ms. Kavita S. Subramanian, a PhD student from the Department of Pharmacology, Faculty of Medicine, University of Malaya has been selected in the 2015 Novartis Next Generation Scientist (NGS) program. The NGS program is an intensive 3 month-long internships at the research site in Basel, Switzerland

- The small non-migratory humpback whale population is genetically distinct, scientists find - Researchers recommend “Critically Endangered” status for isolated whales

The University Malaya led team revealed high levels of previously undiagnosed active TB especially amongst HIV infected prisoners.

Malaysia, with its multi-ethnic population, is a perfect laboratory for scientists to look at how inherited differences in genes can affect the patient’s responses to medications. These genetic differences can be used to predict whether a medication will be effective for a particular person and to help prevent adverse drug reactions.

The Yomiuri Techno Forum was founded in 2011, and have provided support for the development of science and technology in Japan. The organization selects three researchers annually who have shown outstanding achievements.

An automated assessment of multiple datasets using artificial intelligence accurately diagnoses a common cause of blindness

Japanese researchers have identified a mutation associated with a higher incidence of lung cancer in Japanese women who do not smoke, but better survival in lung cancer patients.

(Kanazawa, Japan, 25 June 2013)　 Researchers at Kanazawa University Graduate School of Medical Science in Japan have determined how APOBEC proteins mediate hypermutations that inhibit viral replication. They also identify the host factor protein UNG that can repair these mutations.

Shenzhen, China 8 Jan - Chinese researchers have solved the mystery of the function of sheaths in flowering orchids. In a paper published in PLOS ONE, the team led by Zhong-Jian Liu at the Orchid Conservation & Research Center of Shenzhen and Laiqiang Huang at Tsinghua University found the perch to be essential to orchid reproduction.

(Okayama, Japan, 20 September 2012) - Okayama University researchers demonstrate that cancer stem cells can be produced from normal stem cells for new therapies to combat cancer

(Tokyo, 27 August 2012) Tokyo Tech ‘s Yoshihiro Miyake and colleagues have developed an innovative, non-invasive therapeutic intervention that may improve the mobility, stability, and quality of life of Parkinson’s disease patients.

New Pancreatic Cancer Animal Models to aid Novel Therapy Development. Austrianova Singapore announced today that they and their partners have created a mouse model that mimics human pancreatic cancer.

A large-scale resource for investigating microbial communities throughout the human body and an analysis of these data is reported in two studies in this week’s Nature. Microbial communities that live on and in the human body, collectively known as the ‘microbiome’, are thought to have a critical role in human health and disease.

Researchers at the RIKEN Omics Science Center (OSC) have successfully developed and demonstrated a new experimental technique for producing cells with specific functions. As an alternative to induced pluripotent stem cells, the technique promises to enable faster production of functional cells for use in cancer therapy and other areas.

Mathematical Model Describes the Collaboration of Individual Neurons

Researchers at the RIKEN Omics Science Center (OSC) have developed a robotic workflow for sample preparation on the HeliScope single molecule sequencer which drastically reduces sample preparation time to from 42 days to only 8 days.

A new diagnosis technique developed by researchers at the RIKEN Omics Science Center (OSC) has succeeded in detecting influenza virus infection in only 40 minutes and with one hundred times the sensitivity of conventional methods.

Why don't woodpeckers injure themselves? Researchers at Hong Kong Polytechnic University and the Beihang University in Beijing have been investigating...

A variant of a newly identified gene is linked to increased risk of developing osteoporosis in Japanese individuals

A family tree of the 2009 pandemic influenza viruses in Japan reveals a high rate of viral evolution

Collaborative research from the Tokyo University of Science shows potential for bioengineered mature organ replacement as a next generation regenerative therapy.

Assessing the chemical diversity of genetically modified organisms is an important first step for evaluating their safety

Researchers at the RIKEN Plant Science Center (PSC) have clarified a key epigenetic mechanism by which an enzyme in the model plant Arabidopsis protects cells from harmful DNA elements.

Analysis of mutations of the 2009 pandemic influenza A(H1N1) virus by researchers at the RIKEN Omics Science Center (OSC) has revealed major genetic differences between the virus in its early phase of infection in Japan and in its peak phase.

Monkeys infected with an emerging malaria strain are providing a reservoir for human disease in South-east Asia, according to research published today.

Retinitis pigmentosa (RP) is a cluster of genetically determined eye disorders that cause visual defects such as night blindness and narrowing of the field of vision, due to progressive loss of rod photoreceptors. New work by Zi-Bing Jin and colleagues looks to add a set of powerful new tools for those searching for treatments for RP.

The rapid development of computational tools is shedding light on new genetic and molecular studies, but it is also creating headaches for the scientists involved in this research.

Press Release - Reported in PLoS Computational Biology, the findings offer fundamental insights relevant to a wide range of biological, physical and technical systems.

The discovery of novel risk factors for osteoarthritis illuminates a probable role for the immune system in the pathology of this joint disorder