Development of soft and highly durable brain electrodes that stick to the brain to treat brain diseases

- DGIST Prof. Kim Sohee and team develop soft, flexible, and highly durable brain electrode technology. - Expected to be used in brain-machine interfaces without causing tissue damage, and to treat brain diseases.

□ DGIST (President Lee Kun Woo) Department of Robotics and Mechatronics Engineering Professor Kim Sohee and her research team announced on January 18 (Thursday) the development of a highly durable brain electrode technology that uses soft and flexible materials. The technology is expected to be used in various fields that require connections between the brain and machines, such as electrodes for treating brain diseases that involve long-term implantation.

 

□ Brain electrodes play a key role in measuring brain activity and connecting the brain to machines. However, the existing brain electrodes are either made of hard materials that have to be implanted in the brain, such as silicon, the material for semiconductor circuit chips, or made of thin plastic polymers. Such materials have limited flexibility or cannot be used for an extended period of time because of safety issues arising from the use of thin materials to ensure flexibility.

 

□ Using a rubbery, elastic material that is considerably softer than plastic polymers, Professor Kim and her team developed brain electrodes that stick extremely well to the curved and winding brain surface, and that is tens of micrometers in thickness, making it significantly easier to operate.

 

□ Although these brain electrodes are composed of soft and elastic materials that have similar mechanical and physical properties as brain tissues, their stability in the body's environment has been questioned. Professor Kim and her team confirmed through an eight-month accelerated aging experiment that the electrodes can maintain their performance in measuring brain signals even after long-term use in the body.

 

□ “We have developed brain electrodes that stick quite well to the curved surface of the brain because of their soft and flexible properties, while maintaining stable performance in the body's environment, where a variety of ions and water are present," said Professor Kim. "It may be used as a key technology for brain–machine interfaces (BMIs) and brain–computer interfaces (BCIs) that do not invade brain tissues, as well as for electronic medical devices that require long-term use over several years.”

 

□ Professor Kim participated in this study as a corresponding author, with Dr. Moon Hyun-min (Department of Mechanical Engineering, MIT), Jang Jae-won (Ph.D. candidate, Department of Robotics and Mechatronics Engineering, DGIST), and Park Soo-mi (DGIST alumnus) as co-lead authors. The research was conducted in collaboration with Dr. Kim Joong-hyun of the Osong Medical Innovation Foundation and Professor Kim Jun-sik of the Konkuk University Medical Center. The findings were published online in Sensors and Actuators B: Chemical, a leading international journal in the field of chemical sensors and biosensors, chemical actuators, and analytical microsystems, on December 4, 2023. This research was supported by the Ministry of Science and ICT's Brain Science Fundamental Technology Development Project, Mid-career Research Grant Program, and DGIST Basic Project.

- Ccorresponding Author E-mail Address : [email protected]

 

Published: 26 Jan 2024

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