Biology

Researchers from the Institute of Industrial Science, The University of Tokyo, detail how clusters of cells detach from primary tumors and penetrate blood-vessel walls to enter the bloodstream, enabling them to establish distal metastases

Scientists have identified a brain molecule called NEAT1 that appears to play a central role in triggering light sensitivity (photophobia), a common and debilitating symptom of migraines

- A DGIST research team led by Professors Ko Jaewon and Um Ji Won has identified an interaction mechanism involving proteins that regulate NMDA receptor function - The discovery is expected to provide key clues for the management of mental diseases such as autism and schizophrenia

- A DGIST research team led by Prof. Jiwon Um has revealed that brain inflammation affects nerve cells and synapses, causing repetitive behaviors. - The research is expected to provide new clues for the treatment of brain disorders, including autism spectrum disorder.

Identification of plant species at high risk of extinction in climate-sensitive alpine ecosystems.

Using a new fluorescent mouse model with advanced imaging techniques, researchers have successfully visualized how musculoskeletal components are integrated into the functional locomotor system during embryonic development.

Scientists at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University have captured real-time footage showing how a key hormone receptor activates genes, offering a clearer view into one of the most fundamental Kaprocesses in biology.

How does obesity affect insulin production? Researchers at Tohoku University are shining light on new stages of the ERK pathway.

Researchers from The University of Osaka discover that specific white blood cells and the amount of an inflammation protein in the blood can predict relapse of an autoimmune blood vessel disease.

- DGIST Prof. Yea Kyungmoo and team significantly improve fatty liver, inflammation, and fibrosis in cellular and animal disease models using exosome surface/internal engineering - Therapy displays high biocompatibility, maximizing treatment efficiency as liver-specific drug delivery - Research results are published in the internationally acclaimed journal Biomaterials

- A joint research team from DGIST and Kyungpook National University has developed a tailored protein adapter technology for the surface modification of extracellular vesicles (exosomes) - Recognized for its precision drug delivery platform capable of attaching diverse therapeutics, the study was published as a supplementary cover article in ACS Nano

Raccoons considered to be a source of zoonotic pathogens were monitored

New light-powered DNA detection enables more accessible, affordable genetic analysis

Scientists at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University and colleagues have developed a promising new approach to cancer treatment. By using tiny, naturally occurring particles called extracellular vesicles (EVs), they have created a way to boost the body’s immune system to fight tumors more effectively. This breakthrough could lead to more targeted cancer therapies with fewer side effects.

Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrates a novel approach for nanoscopic profiling of small extracellular vesicles (sEVs) using high-speed atomic force microscopy (HS-AFM) videography. This pioneering method provides an unprecedented level of detail in characterizing sEV subpopulations, offering new insights into their biological roles and potential applications in disease diagnostics.

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in "Nature Communications" how the targeted suppression of lysosome function may lead to brain cancer therapy.

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University and colleagues have achieved a major breakthrough in understanding sperm DNA packaging. Using high-speed atomic force microscopy (HS-AFM), they captured the real-time process of protamine (PRM)-induced DNA condensation, providing critical insights into fertility, genome stability, and future applications in medicine. Their findings are published in "Nucleic Acids Research".

New research in model mice suggests low-dose opioids may help improve social interactions in people with autism spectrum disorder.

- Professor June M. Kwak’s team at DGIST uncovered the cause and mechanism behind the transformation of residual cells in abscission zones into epidermal cells - The research findings were published in the prestigious international journal Nature Plants

An Osaka Metropolitan University-led research team investigated the case of a male Asian small-clawed otter that fell down the stairs while sleeping, after which it developed left-sided paralysis

A genomic study of hydrogen-producing bacteria has revealed entirely new gene clusters capable of producing large volumes of hydrogen.

The presence of T cells with low-levels of Bach2 contributes to the worsening and/or prolongation of allergic dermatitis symptoms

Researchers from The University of Osaka identify a molecule that can support specific therapeutic targeting of AML with chimeric antigen receptor therapy

Understanding this molecular arms race between viruses and plant defenses is essential for developing innovative disease-resistance strategies in agriculture.

Researchers develop innovative phospholipids that improve the functional delivery of mRNA via lipid nanoparticles, paving the way for advanced therapeutic applications.

We created novel artificial cells by encapsulating a riboswitch-gene fusion with wheat germ extract in liposomes. These non-living cells promoted the expression of a glowing protein encoded in the gene in response to an external target at room temperature. They (precisely, a riboswitch in them) can be rationally designed for a user-defined target, allowing a cocktail of artificial cells (each group has a specific riboswitch-gene fusion) to simultaneously detect multiple targets with different glowing proteins.

YNU researchers analyzed how vascular plant species richness, asynchrony, bryophyte cover, and other factors influence the temporal stability of plant communities.

Suppression of the CcMCA1 gene has potential in halting invasive plant species

YNU research team discovered a novel global cooperative phenomenon in cervical cancer cells, suggesting they are metabolically connected.

- A joint research team from DGIST, Kyungpook National University Chilgok Hospital, and Dongguk University has revealed the identity of cervical stem cells for the first time in the world - The research presents new possibilities for cervical cancer prevention and treatment using lactic acid bacteria and lactic acid, published in Nature Communications