Biology

A gene that limits cellular damage could be the key to surviving prolonged cold exposure.

The Androgen Receptor in Mesenchymal Progenitor Cells Drives Skeletal Muscle Mass Regulation

By targeting multiprotein molecule, antibody inhibits bacteria’s growth, pathogenicity

A Duke-NUS Medical School-led study highlights the role of natural killer T cells in influencing the immune response to dengue virus, potentially reducing the severity of subsequent infections.

A research group has developed a new COVID-19 testing system using Janus particles—microparticles with two sides possessing distinctive molecular properties. These particles are engineered to bind specifically to target antigens, such as viral proteins, creating a low-cost, accurate, and rapid means of testing for viral diseases. The system’s versatility means it can potentially be used to test for other diseases and biomarkers linked to other conditions.

Light-induced immunoassay coated with novel coronavirus spike proteins found highly sensitive even with weak light like a laser pointer

Researchers from Osaka University found that T cells recognize neoself-antigens––abnormal, unfolded host proteins presented by major histocompatibility complex II (MHC-II) lacking the invariant chain––as non-self antigens, leading to the development of autoimmunity. Reactivation of Epstein–Barr virus, a known risk factor for lupus onset and exacerbation, increases the presentation of neoself-antigens by MHC-II, which could help explain the link between viral infection and autoimmune disease.

A better understanding of how cells regulate their membranes could lead to new treatments for diseases such as epilepsy and anemia.

Mutant microalgae produce wax esters for biofuel feedstock with improved cold flow

Cleaner wrasse check their body size before fights due to having their own mental representation

Seaweed helps brain health, Whales in long-distance relationships, Jumpstarting male fertility, Demystifying black hole turbulence, Shrimp to steel & Mpox Resources. Read all in the latest Editor's Choice.

Studied oxidative stress and Parkinson’s disease as a case study

Suppression of an enzyme might allow melanocytes to recover

Medaka fish that lacked functional Hmgn2 genes were unable to distinguish between simple shapes, revealing a new function for the regulatory gene.

Feeder-free induced pluripotent stem cells hold hope in therapies for cats’ chronic kidney disease

- DGIST Professor Seo Byeong-Chan’s research team is the first in the world to discover how PAC channels work. - Their research has revealed a method to prevent cell edema and tissue damage, which may help treat cancer and brain diseases.

14-3-3η: A protein that helps fight RNA viruses but can also be manipulated by them. New research reveals its complex role in the immune response

A nonirritant, antibacterial solution to prevent oral inflammation may lie in citrus and coconut chemical compounds

Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin.

Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, used high-speed atomic force microscopy to observe dynamic changes in AMPA receptors, which are vital for brain communication. Their findings, published in ACS Nano, reveal how these receptors adapt during signal transmission and suggest potential targets for neurological therapies.

Professor Hsiao-Wei Yuan from the School of Forestry and Resource Conservation at National Taiwan University (NTU) has been leading a team since 2003 dedicated to the research and protection of the endangered Chinese Crested Tern, also known as the 'Mythical Bird,' with only fewer than 100 individuals remaining. Their efforts have drawn international attention to this species, leading to conservation efforts and showcasing Taiwan's efforts in biodiversity conservation and key research achievements. After 20 years of conservation efforts, the population of Chinese Crested Terns has increased to approximately 150 individuals.

A newly developed compound that reduces harmful inflammation in rats caused by overactive neutrophils shows great potential as a safer treatment for various inflammatory diseases in humans.

One of the smallest lifeforms may have the biggest impact on marine ecosystems. Researchers at Tohoku University modeled how climate change can affect phytoplankton – and our future.

Researchers from Osaka University find that the transcription factor Ikaros binds to Foxp3 to inhibit the expression of target genes, including Ifng, in regulatory T cells

Cell–cell adhesion-induced patterning in keratinocytes can be explained by just starvation and strong adhesion, Hokkaido University researchers find.

A newly discovered mechanism of fear memory formation in mouse brains may help reduce the negative impact of fear and provide new treatment methods for post-traumatic stress disorder (PTSD) in the future , according to a study published on August 5th in the open-access journal Cell Reports by Wen-Hsien Hou (侯文賢) from National Yang Ming Chiao Tung University, Taiwan, and colleagues.

Hidden hand that carves life, Plant-inspired water purification, 3D-printed meals, Fast-glowing molecule, See less to move better. Read all in the latest Editor's Choice.

Applying chaos theory to the movement of iconic arctic whales uncovered a 24-hour diving cycle and a long-range (~100 km) synchronization.

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, IMDEA Nanoscience (Madrid, Spain) and CNB-CSIC (Madrid, Spain) report in ACS Nano experiments that reveal a cycle of conformational stages that recombinant Influenza A genomes pass through during RNA synthesis.

Wild boars and red junglefowl gave rise to common pigs and chickens. These animals’ genes evolved to express themselves differently, leading to signatures of domestication — such as weaker bones and better viral resistance — in pigs and chickens, according to a research team based in Japan.