Biology

Researchers at Kanazawa University report in Cell Reports how alterations in the nuclear pores lead to the degradation of anti-tumor proteins.

In recent years, an emerging zoonotic pathogen called E. albertii, transmitted by wild animals such as raccoons, has garnered attention due to its remarkable similarities to several strains of Escherichia coli (E. coli), including O157, and its potential to cause severe illness, particularly in children. A research group at Osaka Metropolitan University has developed a novel culture medium that allows for the selective cultivation of E. albertii from raccoon fecal samples. This enabled the successful isolation of E. albertii even from samples with very low quantities of this bacterium. Their findings are expected to further elucidate the bacteriological characteristics of E. albertii and to contribute to the control of foodborne illnesses.

DishBrain reveals how human neurons work together to process information. Living model of brain could give insights into the mechanisms of how we understand and experience the world.

Researchers at Kanazawa University report in STAR Protocols procedural details and tips for nanoendoscopy-AFM, for capturing images of nanoscale structures inside living cells.

A long-lived monocarpic species of bamboo, Phyllostachys nigra var. henonis, only flowers once every 120 years before it dies. The upcoming flowering event for this species does not bode well for its continued long-term survival, as most flowers are not producing viable seeds.

Roughly 10% of the proteins in our body rely on zinc. A group of researchers has unearthed the secrets behind a tiny but crucial protein that shuttles zinc ions within our bodies, offering a deeper understanding of how our cells maintain optimal health.

Researchers at Kanazawa University report in Nature Communications how calcium ions can block sodium ion channels located in cell membranes. Structural analysis and computer simulations made it possible to identify where and why calcium ions get stuck.

Study suggests broad-spectrum vaccines with wide coverage necessary to achieve effective immunity against future, functionally-distinct variants.

Researchers have identified a new pathway by which sugar is released by symbiotic algae. This pathway involves the largely overlooked cell wall, showing that this structure not only protects the cell but plays an important role in symbiosis and carbon circulation in the ocean.

Anti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor therapies, they halt tumor progression in mice models.

Japanese fossil forest found, AI finds a way to people’s hearts, Language diversity and child social development & Supplement for kidney disease. Plus Submissions open for Asia Research News 2024. Read all in the latest Editor's Choice.

Hokkaido University researchers found that tiny nematode worm larvae surf electric fields to hitch rides on passing insects.

Researchers from Osaka University clarified the interactions of the proteins Tejas (Tej), Vasa (Vas), and Spindle-E (Spn-E) in the formation of cellular compartments known as nuage and the processing of PIWI-interacting RNA (piRNA) precursors in Drosophila melanogaster ovaries. piRNAs help prevent the transmission of genetic mutations through reproductive cells, and insight into the dynamics of piRNA formation and processing may contribute to our understanding of the mechanisms underlying reproductive disorders, including infertility.

- Collaborative study by Choi, Head of the DGIST Core Protein Resource Center, and Prof. Park from Kyungpook National University uncovers the alarming impact of secondary microplastics on human health! - Environmental model exposes harmful effects of naturally altered secondary microplastic production

A research team from the Graduate School of Rehabilitation Science at Osaka Metropolitan University investigated the electrophysiological benefits of working in the presence of others from the perspectives of brain and autonomic nervous system activity. The researchers found that parasympathetic activity—which indicates relaxation—was significantly higher when two individuals were working separately than when one individual was working alone. This suggests that arranging the former condition in occupational therapy for individuals with high levels of tension or anxiety in clinical settings may potentially help alleviate these feelings.

Dr. Zhang Yi, the lead scientist, and his team of researchers from Canada, Singapore, the UK, have successfully completed a study, comparing the efficiency of various bioreactors in producing Raspberry Ketone through Submerged Fermentation. This research marks the first time such a study has been conducted.

The researchers from Osaka University showed how bone erosion caused by cholesteatoma occurs. This study showed that a subset of cells called osteoclastogenic fibroblasts expresses a protein, activin A, which causes the breakdown of the bones. Because of this discovery, novel medical treatments can be developed as first-line management for cholesteatomas.

Scientists have isolated potent neutralising antibodies from a COVID-19 vaccinated SARS survivor that exhibited remarkable breadth against known sarbecoviruses. The antibodies targeted a conserved region of the spike protein and blocked receptor binding and viral fusion. These findings could guide the development of broadly active therapeutics against current and future coronaviruses.

Illuminating the molecular ballet in living cells, Charting the voyage of marine plastics, A glimpse into the origins of life & Earliest human journeys to Asia. Plus Submissions open for Asia Research News 2024. Read all in the latest Editor's Choice.

A protein that transports lipid into cells reveals clues to treating a major health problem affecting kidneys.

An exquisitely preserved fossil forest from Japan provides missing links and helps reconstruct a whole Eurasia plant from the late Miocene epoch.

Agricultural genetic stories reported at the International Congress of Genetics in Melbourne.

Japan’s population may be on the decline, but it is the opposite for many wildlife species. This has increased the number of human-wildlife interactions. Controversially, lethal management is sometimes employed to manage this issue. But a holistic understanding of the public’s attitude to this approach has been lacking. Now, researchers have surveyed the public’s opinion on the topic, hoping to provide data that can direct future management practices.

US$500,000 Gruber Genetics Prize awarded in Melbourne

Thursday at the International Congress of Genetics in Melbourne

Scientists have combined two light wavelengths to deactivate a bacterium that is invulnerable to some of the world’s most widely used antibiotics, giving hope that the regime could be adapted as a potential disinfectant treatment.

Omega-3 lysolipids are important for protecting the liver from dietary fat, according to Duke-NUS researchers and collaborators from SGH.

Research stories from the International Congress of Genetics in Melbourne Tuesday 18 July 2023

RNases have been proposed as a treatment against systemic autoimmune diseases. Researchers from Osaka University showed that RNases have a dual action. In some cases, RNases are detrimental and stimulate the immune response by promoting the binding of antibodies to their targets. These findings will improve the understanding and treatment of systemic autoimmune disorders.

A research team has discovered an astounding array of unexplored protein folds. This research will expand our understanding of the depth of the protein universe and the possibilities for de novo design of functional proteins.