Biology

News

28 Dec 2020
Investigations of a cellular protein have uncovered a possible link with schizophrenia.
iCeMS Ueda ABCB1
28 Dec 2020
iCeMS scientists have revealed how a transporter protein twists and squeezes compounds out of cells, including chemotherapy drugs from some cancer cells.
24 Dec 2020
Tohoku University scientists have, for the first time, provided experimental evidence that cell stickiness helps them stay sorted within correct compartments during development. How tightly cells clump together, known as cell adhesion, appears to be enabled by a protein better known for its role in the immune system. The findings were detailed in the journal Nature Communications.
24 Dec 2020
Researchers at WPI-IIIS find that normal sleep in mice depends on bacteria that help make neurotransmitters such as serotonin in the gut. The article, “Gut microbiota depletion by chronic antibiotic treatment alters the sleep/wake architecture and sleep EEG power spectra in mice,” was published in Scientific Reports.
24 Dec 2020
Researchers at Tohoku University have developed the first all-in-one miniature pH probe for real-time investigations of intrinsic extracellular pH dynamics in the deep brain structures.
Front Cover
23 Dec 2020
Hokkaido University is pleased to announce the publication of "Tackling Global Issues Vol. 3 FIGHTING THE MENACE OF ZOONOSES," a magazine the University’s research on zoonotic and other infectious diseases.
23 Dec 2020
A transporter protein that regulates cell membrane cholesterol likely played an important role in vertebrate evolution, according to a review published by iCeMS researchers in the journal FEBS Letters.
BioAFMviewer
22 Dec 2020
Atomic force microscopy (AFM) allows to obtain images and movies showing proteins at work, however with limited resolution. The developed BioAFMviewer software opens the opportunity to use the enormous amount of available high-resolution protein data to better understand experiments. Within an interactive interface with rich functionality, the BioAFMviewer computationally emulates tip-scanning of any biomolecular structure to generate simulated AFM graphics and movies. They greatly help in the interpretation of e.g., high-speed AFM observations.
21 Dec 2020
Scientists release genetic results confirming a female turtle captured in October 2020 in Viet Nam is definitively the near extinct Swinhoe’s softshell turtle (Rafetus swinhoei) – also known as the Yangtze giant softshell turtle and Hoan Kiem turtle.
New IRAK4 mutations discovered
21 Dec 2020
Researchers baffled by an infant’s rare encephalitis case unusual in children found unheard-of mutations and a new way to examine the “immunity gene.”
16 Dec 2020
Daegu Gyeongbuk Institute of Science and Technology (DGIST) researchers gain deeper insight into a cell membrane channel, with potential implications for drug development.
Relationship between OHC levels and transcriptome profiles in salmon collected from three areas of the Baltic Sea
16 Dec 2020
Researchers of Ehime University and the University of Helsinki measured hepatic organohalogen (OHC) concentrations and gene expression profiles in Atlantic salmon collected from three areas in the Baltic Sea. The results showed that OHCs and gene expression profiles were individually grouped in three areas and the covariation of the two datasets provided by a multivariate method was significantly similar. This suggests that the gene expression profiles in salmon are affected by OHC contamination.
11 Dec 2020
Recognizing species is important for understanding regional biodiversity and for environmental conservation. However, taxonomic identity is sometimes obscure even with the organisms that are closest to human life.
Turning off gene editing during error-prone cell cycle phases
04 Dec 2020
Turning off gene-editing until it reaches cell cycle phases where more accurate repairs are likely to happen offers a promising fix to CRISPR-Cas9’s problem with unwanted genetic changes.
03 Dec 2020
A team of scientists from Hokkaido University has suggested that marimo maintain their characteristic spherical shape due to the rarity of the formation of reproductive cells.
25 Nov 2020
Scientist's understanding of this microscopic invertebrate has grown after the second discovery of Loricifera near Japan.
23 Nov 2020
Taskforce will look into COVID-19 origins, leveraging expertise in One Health, outbreak investigation, virology, lab biosecurity and disease ecology.
20 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has presented the whole-genome sequence and analyses of the endangered whale shark (Rhincodon typus), the largest extant fish on Earth.
20 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has been selected as the recipient of a large-scale Social Science Korea (SSK) project of the National Research Foundation of Korea.
20 Nov 2020
A research team, affiliated with the Korea Genomics Center (KOGIC) at UNIST has released data from the initial phase of the Korean Genome Project (Korea1K), including information describing 1,094 whole genomes, along with 79 quantitative clinical traits.
20 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has succeeded in unveiling the principle behind the changing sleep patterns, according to the ambient temperature, through the use of Drosophila as a model of sleep.
When researchers inhibited Wnt signalling the anti-cancer drug ETC-159, they found that the reactivation of the hyperactive RAS-MAPK pathway led the cancer cells to undergo senescence, which is an ageing process that results in arrested growth.
20 Nov 2020
Cancer is a disease driven by mutations that alter the way biochemical signals control cell growth, division and migration. Scientists at Duke-NUS Medical School found out that, like Goldilocks, cancer is very picky about getting rapid growth just right.
20 Nov 2020
A new mechanism of action by which misfolded proteins cause indirect damage to neurons
19 Nov 2020
A repetitive DNA sequence that causes health risks when it malfunctions can now be watched inside living cells using a synthetic tool
The Elthusa splendida specimen described in the paper (Photo: Shinpei Ohashi).
17 Nov 2020
Scientists have discovered an extremely rare species of cymothoid from the mouth of a museum specimen of a deep-sea shark caught from the East China Sea, suggesting its wide distribution around the globe.
Image for sedimentary DNA analysis
10 Nov 2020
Far too little is known about the long-term dynamics of the abundance of most macro-organism species. We used sedimentary DNA technology to quantify marine fish DNA abundance in sediment sequences spanning the last 300 years. This study first shows the existence of fish DNA in the sequences and proves that fish abundance can be tracked using sedimentary DNA, highlighting the utility of sedimentary DNA for researchers to acquire lengthy records of macro-organism species abundance.
06 Nov 2020
Testing for mutations in RNF43, a protein that affects key cancer cell-growth pathway Wnt, gives clinicians actionable insights to tailor treatments better.
04 Nov 2020
Innovative research by scientists at Duke-NUS Medical School has shed light on the mysterious role of long non-coding RNAs in the development of pancreatic cancer and suggests potential new targets for precision cancer therapies.
Broken Hill Mine, Kabwe
04 Nov 2020
Residents of Kabwe Town, Zambia, have very high blood levels of lead and cadmium, to such an extent that the symptoms of toxicity have been clinically observed.
03 Nov 2020
A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has proposed a new technique that controls the spatiotemporal resolution of Structured Illumination Microscopy (SIM) within a single image.

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