Biology

The diversity of threatened fish in estuaries increases when surrounded by forest cover, whereas estuaries surrounded by farmland show the opposite effect.

Malfunctioning of the so-called Hippo signalling pathway within animal cells leads to irregular activity of proteins that regulate genes involved in cell proliferation. Researchers have identified a key step in the process of this aberration, opening the door to new therapeutics for cancers such as head-and-neck squamous cell carcinoma and lung adenocarcinoma.

The world’s largest analysis of gastric tumour cells provides a launch pad for scientists to plan more effective therapies.

Giants in History: Maqsudul Alam (14 December 1954 – 20 December 2014) was a biologist from Bangladesh who is renowned for his research on genome sequencing.

Researchers reveal correlation between ribotype (RT) strains of Cutibacterium acnes, which are found in human skin, and the lifespan of the nematode Caenorhabditis elegans. Strains RT4 and 8, which are associated with acne in human skin, shortened the lifespan of the nematode, while RT6, which are predominantly found in healthy human skin, did not. Also, it was found that the healthy skin-related RT6 strain of C. acnes improved C. elegans resistance to the pathogenic organism Staphylococcus aureus.

Researchers have revealed in an animal model that ImmuBalance, a fermented soybean product, is effective in suppressing airway inflammation caused by asthma. Results showed a decreased presence of eosinophils in bronchoalveolar lavage fluid, a decrease in mucus production in the bronchial epithelium, and a suppression of proteins that induce eosinophilic inflammation.

Biologists from Hong Kong Baptist University (HKBU) have discovered in Hong Kong waters a new species of hard coral and two new species of nudibranch, a type of marine mollusc, that have never been identified anywhere else in the world. The discoveries of new species from these commonly seen animal groups are a vivid reflection of Hong Kong’s rich marine biodiversity.

Just as humans may leave their home five minutes early to avoid a talkative neighbor or depart work late to avoid a rude coworker, carnivorous mammals may go out of their way to avoid other species. But they’re not trying to navigate awkward social interactions; rather, they are negotiating space and resources for survival.

An ambitious project using cutting edge environmental DNA, known as eDNA, to understand the richness of biodiversity of UNESCO’s marine World Heritage sites launches today.

Researchers from Korea reveal the key protein involved in the development of aggressive prostate cancer

Researchers from The University of Tokyo Institute of Industrial Science describe a novel feature of the immune response to certain viruses such as measles

Direct evidence that microtubules function as mechano-sensors and regulate the intracellular transport of molecules has been reported, leading to new possibilities in the fields of biomechanics, medicine, and biosensors.

Coral reefs, comprising some of the most diverse and delicate ecosystems under water, are under immense stress. From global warming to pollution to pathogens, many of the reef-building coral species are listed as threatened or endangered. But, according to researchers in Japan, the corals may have an unlikely ally: bacteria.

Researchers from DGIST explain how DNA is compacted to a million-times its full length in sperm cell nuclei

A previously unknown virus that can infect humans and cause disease has been identified by scientists in Japan. The novel infectious virus, named Yezo virus and transmitted by tick bites, causes a disease characterized by fever and a reduction in blood platelets and leucocytes.

Novel design of brain chip implant allows for measuring neuronal activity while simultaneously delivering drugs to the implant site

Geb Impact aims to scale up microalgae production to provide novel super food ingredient by cost-effective mass cultivation of microalgae

While the Covid-19 pandemic is ongoing, another public health threat, antibiotic resistance, continues unabated. Microbiologists and chemists from two universities in Hong Kong recently made a breakthrough in synthesizing the first vaccine against one of the most deadly antimicrobial resistant pathogens, Acinetobacter baumannii (A. baumannii). The vaccine shows good protection against the superbug in mice, indicating great potential as a vaccine for humans.

The missing link isn’t a not-yet-discovered fossil, after all. It’s a tiny, self-replicating globule called a coacervate droplet, developed by two researchers in Japan to represent the evolution of chemistry into biology.

Single cell analyses reveal hidden turgor-associated metabolic changes and water flow across the flesh in watercored apples

Võ Quý (31 December 1929 – 10 January 2017) was a Vietnamese ornithologist who studied the destruction of tropical forests and agricultural lands in Vietnam by Agent Orange, a herbicide used by the U.S. military during the Vietnam War.

A specially designed lipid nanoparticle could deliver immune-signaling molecules into liver macrophage cells to overcome resistance to anti-tumor immunotherapy.

Genetic and epigenetic profiling of hundreds of hepatoblastoma tumors have revealed many of its secrets, long unknown to those researching and treating what is the most common type of liver tumor in children.

Using the lamprey, researchers from Japan analyzed the photosensory mechanism of the pineal organ, also called the pineal gland, in non-mammalian vertebrates and discovered a novel mechanism of pineal color discrimination (two-cell system) in which two types of photoreceptor cells, each containing two different opsins, are used to detect color. This discovery may provide insight into the evolution of color detection in other animals, including color vision in humans.

New research published in Stem Cell Reports has found elevated cholesterol supply from astrocytes to neurons in the model of Alzheimer's disease (AD) brains, suggesting that modulating brain cholesterol could be explored in the search of treatment options for the devastating, degenerative disease.

When it comes to cancer, clarity is key. The ability to visualize cancerous tumors and metastatic tissue three dimensionally (3D) can help clinicians diagnose the precise type and stage of cancer, while also informing the best treatment methods. To obtain an even clearer tissue for imaging, a research team based in Japan has tested the effectiveness of specialized hydrogels. Acting as a 3D molecular network, these hydrogels can rapidly remove fats from tissues, which are a factor in tissue opacification, without losing their structure. The material is used in several biomedical devices, including contact lenses.

iCeMS scientists and colleagues have designed a molecular code that powers up cancer-fighting immune cells.

Abnormally high levels of DNA methylation have been identified in dogs exposed to high levels of lead near a mining area in Kabwe, Zambia, by a team of scientists from Japan and Zambia.

Giants in History: Chinese agronomist Yuan Longping (7 September 1930 – 22 May 2021) developed the first varieties of the high-yield, hybrid rice that brought food security to multiple countries including China, which had been ravaged by food shortages as recently as the mid-20th century.

Researchers have identified a potential reason why lower numbers of COVID cases have appeared amongst smokers compared to non-smokers, even as other reports suggest smoking increases severity of the disease.