Peer Reviewed

Scientists at Hokkaido University and collaborators have identified how inflammatory changes in tumors caused by chemotherapy trigger blood vessel anomalies and thus drug-resistance, resulting in poor prognosis of cancer patients.

"Neuromorphic" refers to mimicking the behavior of brain neural cells. When one speaks of neuromorphic computers, they are talking about making computers think and process more like human brains-operating at high-speed with low energy consumption.

Researchers at Kanazawa University report in the Biophysical Journal that the process of cell removal from an epithelial layer follows from an inherent mechanical instability. Moreover, the forces generated by an extruding cell can drive the extrusion of other cells in a particular direction.

Scientists are looking for ways to make millions of molecule-sized robots swarm together so they can perform multiple tasks simultaneously.

COVID19 is teaching us several new lessons and also preaching us to learn from the past experiences.

Researchers at the University of Tsukuba and RIKEN in Japan spark a hibernation-like state in mice—a species that does not naturally hibernate

We move our eyes several times per second. These fast eye movements, called saccades, create large image shifts on the retina - making our visual system work hard to maintain a stable perceptual world. Remapping the retinal image compensates for this; however, errors in actual eye movements cause image shifts, even with remapping.

A new study reveals that asteroid impact sites in the ocean may possess a crucial link in explaining the formation of the essential molecules for life. The study discovered the emergence of amino acids that serve as the building blocks for proteins - demonstrating the role of meteorites in bringing life's molecules to Earth, and potentially Mars.

Podonychus gyobu sp. nov., a second species of the genus Podonychus Jäch & Kodada, 1997, hitherto known only to inhabit Indonesia, is reported to have been found in Kyushu, Japan. The endophallic structures and the larva of P. gyobu sp. nov. are described.

A transparent container made by Nagoya University researchers allows easy and quick grafting of very young plants, with benefits for agriculture and plant research.

Hokkaido University scientists have succeeded in synthesizing an α,α-difluoroglycine derivative, a type of α-amino acid, based on a reaction path predicted by quantum chemical calculations. This novel method, combining experimental chemistry and computational chemistry, could innovate the development of new chemical reactions.

A group of Japanese scientists has developed an ultrastable, selective catalyst for dehydrogenate propane – an essential process to produce the key petrochemical substance of propylene – without deactivation, even at temperatures of more than 600°C.

Researchers from University of Tsukuba and the University of Tokyo identify neurons responsible for memory consolidation during REM sleep

A highly accurate machine learning tool could help doctors tailor individualized treatments for people with glioma brain tumours.

The present study screened known and unknown organohalogen compounds present in mussel and sediment samples from Hiroshima Bay. The results provided scientific evidence that unknown mixed halogenated compounds are ubiquitous in the coastal environment and possess bioaccumulative potential as high as persistent organic pollutants.

With increasing unemployment, economists are devising and proposing economic measures that could help ensure a sustainable increase in consumer spending and circumvent a long-term economic recession. However, whether the proposed economic measures are going to provide a long-term solution to these problems remains a concern.

An international collaborative team from PROS Ehime University and CellFee Science, Japan; the Walter and Eliza Hall Institute, Australia; Pasteur Institute, France; and Foundation for Innovative New Diagnostics, Switzerland developed a new diagnostic blood test which detects recent exposure to ‘vivax’ malaria. The new test can also identify people who may harbor dormant liver-stage malaria parasites, which can cause illness. This new diagnostic approach has the potential to enhance malaria surveillance and accelerate elimination.

(1) The development of solid state and time-step VCD methods opened a new horizon to reveal the mechanism of chirality amplification from microscopic to supramolecular scales. (2) The authors were selected as PCCP Emerging Investigators of the Royal Society of Chemistry.

A team of scientists and researchers from A*STAR’s Singapore Immunology Network and Jinan University, Guangzhou, have deciphered human embryonic immune cell development and discovered how the earliest macrophages in humans, a type of white blood cell of the immune system, stems from a distinct embryonic source and not the bone marrow.

An adenovirus is now better able to target and kill cancer cells due to the addition of an RNA stabilizing element.

The generation of alkyl radicals was achieved by direct visible-light excitation of the organoborate complex, which was designed and synthesized from “boracene,” which has a boron atom in the tetracene-like skeleton. The alkyl radicals thus obtained could be used as a carbon source for chemical reactions, enabling the synthesis of complicated/bulky organic compounds. The present study offers a new protocol for organic synthesis, which is expected to accelerate e.g. drug discovery.

A re-analysis of dinosaur skulls from northern Alaska suggests they belong to a genus that lived over a broad latitudinal range extending into the Arctic.

Even though the deeper layers of the ocean are warming at a slower pace than the surface, animals living in the deep ocean are more exposed to climate warming and will face increasing challenges to maintain their preferred thermal habitats in the future.

Wastewater could be used as a surveillance tool to monitor the invasion, spread and eradication of COVID-19 in communities.

Researchers have succeeded in detecting anti-avian influenza virus antibody in blood serum within 20 minutes, using a portable analyzer they have developed to conduct rapid on-site bio tests. If a suitable reagent is developed, this technology could be used to detect antibodies against SARS-CoV-2, the causative virus of COVID-19.

When studying the larval morphology of Toramini (Coleoptera: Erotylidae) we found that larvae of the genus Toramus attach their exuviae to their distal abdomen, with each exuvia from the preceding instar attached to the next to form a vertical pile. Exuvial attachment is facilitated by modified hook-like setae with flattened shafts inserted into the exuvia of the previous instar. We discuss the possibility that the exuvial attachment serves as a kind of autotomy — “exuvial autotomy”.

A group of Hokkaido University researchers has developed a paper-based device that can easily and cheaply measure lithium ion concentration in blood, which could greatly help bipolar disorder patients.

Research into how the SARS-CoV-2 virus induces death is suggesting potential treatments for its most destructive complications.

New data on East Asian populations will guide researchers and clinicians to develop novel therapeutic strategies tailored to individual lung cancer patients.

Scientists say some myelin-damaging disorders have a distinctive pathology that groups them into a unique disease entity.