Biology Cell biology

Scientists at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University have captured real-time footage showing how a key hormone receptor activates genes, offering a clearer view into one of the most fundamental Kaprocesses in biology.

Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrates a novel approach for nanoscopic profiling of small extracellular vesicles (sEVs) using high-speed atomic force microscopy (HS-AFM) videography. This pioneering method provides an unprecedented level of detail in characterizing sEV subpopulations, offering new insights into their biological roles and potential applications in disease diagnostics.

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in "Nature Communications" how the targeted suppression of lysosome function may lead to brain cancer therapy.

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University and colleagues have achieved a major breakthrough in understanding sperm DNA packaging. Using high-speed atomic force microscopy (HS-AFM), they captured the real-time process of protamine (PRM)-induced DNA condensation, providing critical insights into fertility, genome stability, and future applications in medicine. Their findings are published in "Nucleic Acids Research".

Researchers from The University of Osaka identify a molecule that can support specific therapeutic targeting of AML with chimeric antigen receptor therapy

Suppression of the CcMCA1 gene has potential in halting invasive plant species

Cryo-electron microscopy reveals molecular structure of twin motors that power mycoplasma’s ability to glide

Asteroid contains life’s building blocks, How fish detect color, Eco-friendly artificial muscles, Cell imaging gets a glow-up, Quantum gem, Healing skin with milkfish. Plus the 2025 Magazine is here, Read all in the latest Editor's Choice.

As populations age worldwide, diseases like pulmonary fibrosis are increasingly impacting life expectancy and quality. Duke-NUS researchers have identified that blocking specific proteins in immune cells can significantly reduce or reverse lung scarring. This discovery paves the way for novel treatments that could potentially reverse damage from pulmonary fibrosis.

Latest findings on the significance and interaction between cell death and cellular senescence in cancer

At Duke-NUS Medical School scientists are pioneering breakthroughs in precision medicine and regenerative therapies, targeting everything from muscle loss to dramatically extending our years of health.

Zebrafish arrestins take turns inactivating key protein depending on intensity of light

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have discovered how a protein called lamin A helps repair the protective barrier around a cell's DNA. The findings reveal lamin A's unique role and its potential for treating Hutchinson-Gilford Progeria Syndrome, a rare disorder that causes premature aging.

Conversely, role in controlling cell proliferation might lead to novel tumor therapies in humans

Arabidopsis thaliana mutant’s lack of KNS3 means boric acid channels don’t arrive properly at plasma membrane

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary in an in vitro model system.

Mirror, mirror, in my tank, who’s the biggest fish of all? Sigma bond spotted, Balancing cell membrane, Exploring quantum squeezing and Outbreak preparedness. Read all in the latest Editor's Choice.

Light-induced immunoassay coated with novel coronavirus spike proteins found highly sensitive even with weak light like a laser pointer

A better understanding of how cells regulate their membranes could lead to new treatments for diseases such as epilepsy and anemia.

Suppression of an enzyme might allow melanocytes to recover

Feeder-free induced pluripotent stem cells hold hope in therapies for cats’ chronic kidney disease

Cell–cell adhesion-induced patterning in keratinocytes can be explained by just starvation and strong adhesion, Hokkaido University researchers find.

Zika virus vaccine targets brain cancer, 120-year quest to farm lobsters, Arctic nightlife bursts with sound, Eating a robot, Molecular orientation is key & New treatment for ALS and dementia. Read all in the latest Editor's Choice.

May prove to be therapeutic target in breast cancer treatment

Ancient Mars biomolecules, Gargling away bad bacteria, Molecule glasses magnify life-chemical observations, Cholesterol and cancer link, Quantum electronics leap, Plus our updated Experts for Media: Women list & Asia Research News 2024 is here. Read all in the latest Editor's Choice.

A new study highlights a potential therapeutic target for immune-related disorders, such as multiple sclerosis and asthma.

Scientists from Duke-NUS Medical School have developed a new approach using the Zika virus to destroy brain cancer cells and inhibit tumour growth, while sparing healthy cells.

A novel method for studying genes in testicular cells of living animals could lead to breakthroughs in male contraception and fertility treatments.

A new user-friendly tool helps researchers explore how gene activity is influenced by chemical modifications, providing insights into disease and paths to new treatments.

Regenerative therapy to treat heart failure is more effective when the mitochondria of the regenerative cells are activated prior to treatment.