Biology Cell biology

As populations age worldwide, diseases like pulmonary fibrosis are increasingly impacting life expectancy and quality. Duke-NUS researchers have identified that blocking specific proteins in immune cells can significantly reduce or reverse lung scarring. This discovery paves the way for novel treatments that could potentially reverse damage from pulmonary fibrosis.

Latest findings on the significance and interaction between cell death and cellular senescence in cancer

At Duke-NUS Medical School scientists are pioneering breakthroughs in precision medicine and regenerative therapies, targeting everything from muscle loss to dramatically extending our years of health.

Zebrafish arrestins take turns inactivating key protein depending on intensity of light

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have discovered how a protein called lamin A helps repair the protective barrier around a cell's DNA. The findings reveal lamin A's unique role and its potential for treating Hutchinson-Gilford Progeria Syndrome, a rare disorder that causes premature aging.

Conversely, role in controlling cell proliferation might lead to novel tumor therapies in humans

Arabidopsis thaliana mutant’s lack of KNS3 means boric acid channels don’t arrive properly at plasma membrane

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary in an in vitro model system.

Mirror, mirror, in my tank, who’s the biggest fish of all? Sigma bond spotted, Balancing cell membrane, Exploring quantum squeezing and Outbreak preparedness. Read all in the latest Editor's Choice.

Light-induced immunoassay coated with novel coronavirus spike proteins found highly sensitive even with weak light like a laser pointer

A better understanding of how cells regulate their membranes could lead to new treatments for diseases such as epilepsy and anemia.

Suppression of an enzyme might allow melanocytes to recover

Feeder-free induced pluripotent stem cells hold hope in therapies for cats’ chronic kidney disease

Cell–cell adhesion-induced patterning in keratinocytes can be explained by just starvation and strong adhesion, Hokkaido University researchers find.

Zika virus vaccine targets brain cancer, 120-year quest to farm lobsters, Arctic nightlife bursts with sound, Eating a robot, Molecular orientation is key & New treatment for ALS and dementia. Read all in the latest Editor's Choice.

May prove to be therapeutic target in breast cancer treatment

Ancient Mars biomolecules, Gargling away bad bacteria, Molecule glasses magnify life-chemical observations, Cholesterol and cancer link, Quantum electronics leap, Plus our updated Experts for Media: Women list & Asia Research News 2024 is here. Read all in the latest Editor's Choice.

A new study highlights a potential therapeutic target for immune-related disorders, such as multiple sclerosis and asthma.

Scientists from Duke-NUS Medical School have developed a new approach using the Zika virus to destroy brain cancer cells and inhibit tumour growth, while sparing healthy cells.

A novel method for studying genes in testicular cells of living animals could lead to breakthroughs in male contraception and fertility treatments.

A new user-friendly tool helps researchers explore how gene activity is influenced by chemical modifications, providing insights into disease and paths to new treatments.

Regenerative therapy to treat heart failure is more effective when the mitochondria of the regenerative cells are activated prior to treatment.

Researchers at Kanazawa University report in Journal of Cell Science on a novel role of the small Ca2+-binding protein S100A11 in focal adhesion disassembly.

A study led by Duke-NUS Medical School has found an important connection between cancer, stem cells and the building blocks of cholesterol. Specifically, the research reveals how the enzyme FAXDC2 influences cancer cell growth and differentiation through its role in cholesterol synthesis, suggesting possible new approaches to cancer treatment.

Unleashing stem cells from dog urine, Electronic Tongue, Tapping into human motion energy, How neurons network, and A radical use for plastic bags. Plus Communicating science two decades on. Read all in the latest Editor's Choice.

Scientists at Osaka Metropolitan University have developed an efficient, non-invasive, and pain-free method to generate canine-induced pluripotent stem cells (iPSCs). They identified six reprogramming genes that can boost canine iPSC generation by 120 times compared to conventional methods using fibroblasts. The iPSCs were created from urine-derived cells without the need for feeder cells, an impossible feat until now. Their findings are expected to advance regenerative medicine and genetic disease research in veterinary medicine.

We’re all familiar with our body’s internal clock: it gives us cues on when to wake and when to rest, but it also can determine the rate and time of day at which your body most effectively heals wounds.

Scientists uncover genetic factors allowing for the early prediction of intestinal metaplasia patients who may have higher risks of developing stomach cancer, enabling early detection, diagnosis and targeted prevention.

Researchers at Kanazawa University report in the Journal of Physical Chemistry Letters high-speed atomic force microscopy studies that shed light on the possible role of the open reading frame 6 (ORF6) protein COVID19 symptoms.

A new technique allows researchers to map how the cellular ‘skeleton’ adapts to external stress.