Biology Cell biology

News

18 Sep 2020
Drugs tackling chronic myelogenous leukemia have completely transformed prognoses of patients over the last couple of decades, with most cases going into remission. But drug resistance can occur, leading to relapses. Targeting the lipids involved in regulating part of a leukemia stem cell’s life span offers a potential second route to defeat the disease—and solid tumorous cancers as well.
15 Sep 2020
A team of scientists has unraveled the molecular mechanism behind one of the causes of colorectal cancer, and a treatment target.
Macrophage Activation Syndrome in COVID-19
08 Sep 2020
Scientists review macrophage activation syndrome — a feature of the cytokine storm that kills patients with severe cases of COVID-19, as well as possible treatments.
07 Sep 2020
Scientists are learning about species adaptation by comparing their stem cell-related genes.
04 Sep 2020
Pregnant mice fed diets high in omega-6 fats and low in omega-3 fats are shown in a new study to produce offspring whose brains had a higher level of dopamine-producing neurons—the neurological reward system. These mice went on to chase hyper-caloric diets, suggesting that the fats in a pregnant mother's diet may control the eating habits of her children, and potentially offering a new obesity-prevention strategy.
Hypothesis for mechanism of action of IL-34 in TNBC
21 Aug 2020
Hokkaido University scientists have shown that Interleukin-34 is a prognostic marker and drug target for Triple Negative Breast Cancer.
06 Jul 2020
Researchers at Kanazawa University report in Biomaterials a high-speed atomic-force microscopy study of protein filaments in the nuclear pore complex. The visualization in real-time of the filaments’ dynamics is an important step in our understanding of molecular transport mechanisms between a cell nucleus and its surrounding medium.
iCeMS hasegawa malaria india
02 Jul 2020
A method that involves infecting liver cells with mosquito-bred parasites could improve the study of malaria in India.
20 Jun 2020
Researchers at Kanazawa University report in the Biophysical Journal that the process of cell removal from an epithelial layer follows from an inherent mechanical instability. Moreover, the forces generated by an extruding cell can drive the extrusion of other cells in a particular direction.
iCeMS glioma classification
03 Jun 2020
A highly accurate machine learning tool could help doctors tailor individualized treatments for people with glioma brain tumours.
12 May 2020
In a recent study published in Molecular Cell, researchers at Kanazawa University report the role of cellular structures called PML bodies in regulating gene function
16 Apr 2020
A small mitochondrial protein is necessary for energy production and its malfunction could be behind a range of degenerative diseases, according to study by Duke-NUS Medical School and their collaborators.
01 Apr 2020
A research team led by Professor Kin-ming KWAN from the School of Life Sciences at The Chinese University of Hong Kong (CUHK) has recently discovered a novel mechanism by which extrinsic signaling factors modulate the fate transition of neural progenitors to allow the generation of specific neuronal subtypes. This work provides important insight into stem cell biology and the regeneration of neuronal cells, and contributes to the development of neurological therapy for diseases like autism spectrum disorders and hereditary cerebellar ataxia. The research is published in the renowned international scientific journal Cell Reports.
26 Mar 2020
In a recent study published in Autophagy, researchers at Kanazawa University show how abnormalities in a gene called TPR can lead to pediatric brain cancer
Eye blinking on-a-chip image
24 Mar 2020
A new approach could lead to “cornea-on-a-chip” devices that more accurately test the effects of drugs on the human eye.
19 Mar 2020
Environmental changes trigger tiny RNA segments to modify plant pores involved in photosynthesis.
28 Feb 2020
A new compound with the potential to turn genes on and off could lead to new cancer and hereditary disease treatment strategies.
23 Dec 2019
NUS researchers found that chevron patterns in fish swimming muscles require physical forces to correctly develop, not only from genetic instruction or biochemical pathways.
A research team, led by Prof June M. Kwak
06 Dec 2019
Scientists in Korea find a protein that mediates the interaction between the cellular systems involved in rapid responses against foreign genes in plants
26 Nov 2019
Researchers from the Mechanobiology Institute at the National University of Singapore have shown that cells can attach to the fibrous protein meshwork that surrounds them only if the fibres are spaced close enough. The team’s findings can explain the abnormal motility patterns displayed by cancer cells.
29 Aug 2019
A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has discovered that restoring a gene altered in Down syndrome called the Down syndrome critical region 1 (DSCR1) rescued adult neurogenesis and learning and memory defects in a Down syndrome mouse model (Ts65Dn).
Adenine deaminase fused nSpCas9-NGv1 can induce the A-to-G substitution in the target sequence with NG PAM
19 Jul 2019
Researchers in Japan have developed a new genome editing technology in rice.
Lignin
20 Mar 2019
A honeycomb-shaped brace in plants keeps them fit by precisely coordinating the discarding of organs, such as flowers and leaves.
Image Name
07 Nov 2018
New research documents how modifications to RNA keep nerve junctions flexible.
Cell survival under different pretreatment conditions.
25 Oct 2018
The innate immune system may be able to be trained to react to viral infections more efficiently by repeated exposure to anti-viral signaling molecules.

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Researchers

My research background covers multidisciplinary fields such as Pharmaceutics, Cancer Nanomedicine, Bioengineering and Organ-on-a-chip platforms. My current research focuses on the development of dynamic biological barriers on a chip such as blinking human cornea on a chip.
Professor Ahmed Al-Haddad, M.Sc., Ph.D. (Germany) is currently Professor of Microbiology and Medical Microbiology at College of Medicine and Health Sciences, Hadhramout University-Yemen. He is the Founding-Dean of the first Faculty of Nursing in Yemen. He has over fifteen years of research and teaching experience in various domains of life sciences. Al-Haddad has published many peer reviewed articles and conference papers in the areas of molecular biology, microbiology and antibiotics in National and International journals. He is reviewer in different national and international Scientific Journals such as Annals of Clinical Microbiology and Antimicrobials, Journal of Microbiology and Antimicrobials, Sultan Qaboos University Medical Journal, British Biotechnology Journal. He is a member of various national and international scientific organizations.
Toru Kondo is Professor of the Division of Stem Cell Biology at the Institute for Genetic Medicine, Hokkaido University.