13 Apr 2020
The best timing for endoscopy of patients with acute upper gastrointestinal bleeding is still controversial among the medical community. A recent study conducted by the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) found that for patients with overt signs of acute upper gastrointestinal bleeding, urgent endoscopy performed within 6 hours after gastroenterological consultation was not associated with lower mortality and risk of further bleeding, compared with endoscopy performed between 6 and 24 hours after consultation. In other words, earlier endoscopy did not lower mortality nor improve outcomes. The study results have just been published in the top medical journal, The New England Journal of Medicine (NEJM).
31 Mar 2020
New findings show that the formation of amyloid plaques drives damage and tissue loss in the brain during Alzheimer’s disease in animals, but lithium reduces the life-shortening effects of this loss.
30 Mar 2020
To support the fight against the COVID-19 pandemic, from March 29, the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) has offered to conduct, for free, stool tests for asymptomatic children coming to Hong Kong by air to screen for possible COVID-19. The test currently employed by the Department of Health relies on collection of respiratory samples. The false negative rate of deep throat saliva test increases to over 40% with improper collection technique. Collection is particularly difficult in young children and infants. The potentially high false negative rate of the current test for children is therefore of great public health concern. The stool test that CU Medicine has developed is non-invasive, accurate and is potentially a better option for screening test for asymptomatic populations such as young children and infants. By conducting stool tests for children, CU Medicine aims to help identify asymptomatic children carrying the COVID-19 virus as early as possible in order to stop its spread through our community.
27 Mar 2020
A Communique from the InterAcademy Partnership urges countries to collaborate, use and share science-based information, and help the developing world.
27 Mar 2020
Screening is important for the early detection of cervical cancer, but rates were significantly affected, in some areas for years, following a devastating earthquake and tsunami in Japan.
25 Mar 2020
Some trans fats enhance a pathway inside the cell that leads to cell death. Drugs targeting this mechanism could help address diseases associated with these fats.
23 Mar 2020
Nested in the long-running Singapore Chinese Health Study, a new study by researchers in Singapore, based on data from over 60,000 middle-aged to older adults, has found that people who suffer from diabetes and who are also underweight have a much higher risk of active tuberculosis (TB) than their heavier counterparts, supporting calls for TB screening among these patients.
17 Mar 2020
The Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) analysed more than 300 specimens (including sputum, nasopharyngeal swabs, deep throat saliva, blood, urine and stool) from 14 Hong Kong patients confirmed with COVID-19 and discovered that the virus was detectable in the fecal samples of all patients, regardless of the degree of illness. Three out of 14 patients still had viruses in their stool samples even though the virus was no longer found in sputum, nasopharyngeal and deep throat saliva samples. This finding suggests that virus shedding in stool is common and can be an alternative screening tool. Importantly, we should not overlook the potential risk of environmental contamination by virus shedding in stool.
12 Mar 2020
Studying Finnish genes leads to unique revelations about the development of a serious complication of diabetes, and informs an ongoing genomic study of a Singaporean cohort as part of Singapore’s Diabetes Study in Nephropathy and other Microvascular Complications (DYNAMO).
11 Mar 2020
When it comes to awareness of social and legal services available to people with dementia, financial knowledge is key
11 Mar 2020
・A novel pathway of L-fucose metabolism was discovered in strictly anaerobic and pathogenic bacterium. ・The genetic context in bacterial genomes and the screening for potential substrates can help identify the biochemical functions of bacterial enzymes. ・No homologous pathway is found in humans or in probiotic bacteria.
07 Mar 2020
Computerized sound-cognitive therapy could be a new potential treatment for children with attention deficit hyperactivity disorder (ADHD).
26 Feb 2020
The Hong Kong Polytechnic University (PolyU) has been collaborating with Queen Elizabeth Hospital (QE) and the Hospital Authority (HA) respectively to design and produce 3D-printed eye shields and face shields.
22 Feb 2020
Attendees’ health and safety “utmost priority”
19 Feb 2020
Multi-country intervention trial to improve hypertension management, led by Duke-NUS Medical School in Singapore, in partnership with the International Centre for Diarrhoeal Diseases Research, Bangladesh (ICDDR,B), Aga Khan University in Pakistan, the University of Kelaniya in Sri Lanka and the Singapore Clinical Research Institute (SCRI), leads to “clinically meaningful” reductions in blood pressure and better blood pressure control in patients receiving the multi-component intervention. Researchers call for national scale-up of the intervention.
19 Feb 2020
The novel coronavirus COVID-19 worries people around the world as more cases have been reported. In order to provide insights into the epidemic control, the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) has been working on several studies on the outbreak, including community studies. The Jockey Club School of Public Health and Primary Care under the Faculty launched an online survey within 36 hours after confirmed COVID-19 cases were first reported in Hong Kong. The research team has conducted the survey with over 1,000 residents in town and collected information which investigate public’s risk perception and psychobehavioral responses. Results showed majority has difficulty to adopt social distancing.
17 Feb 2020
The precipitous drop in HPV vaccination rates after suspension of proactive recommendations by the government in 2013 could result in an additional 25,000 cervical cancer cases and more than 5,000 additional deaths among females born between 1994 to 2007 in Japan. However, swift action by the government could mitigate much of this damage according to a study in Lancet Public Health.
17 Feb 2020
INTERPHEX Week Osaka is a B to B trade show specialised in pharmaceutical R&D and manufacturing which will be held in Osaka, the largest city in western Japan.
11 Feb 2020
New Delhi – To tackle the escalating problem of antimicrobial resistance, a new collaboration platform was launched in New Delhi, India, on 11 February. The platform, initiated by Stockholm International Water Institute (SIWI), will bring together actors from civil society, governments and the pharmaceutical industry. It could mean a major breakthrough for the responsible manufacturing of antibiotics and reduce the risk of the industry itself contributing to the spread of antimicrobial resistance.
07 Feb 2020
EmTech Asia 2020 has been postponed to 4-5 August 2020 from its original February dates due to the Covid-19 situation in Singapore having higher public health impact.
07 Feb 2020
The Leona M. and Harry B. Helmsley Charitable Trust awarded a USD $2.5 million grant (equivalent to approximately HKD 19.5 million) to the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) to study gut microbiota of pregnant mothers and babies to determine how early life environmental and dietary factors contribute to the development of Crohn’s disease. This study will assess how early life exposures can influence the child’s health and be harnessed for disease risk prediction, prevention and treatment.
07 Feb 2020
The Department of Paediatrics and the Department of Chemical Pathology of the Faculty of Medicine at The Chinese University of Hong Kong (CUHK) have collaborated with researchers from Germany, Finland and mainland China in a study that looks into the effect of exposing children to a farm environment to prevent allergic asthma.
07 Feb 2020
The way research in bioprinting will be taken forward has been laid out in this roadmap for the field.
06 Feb 2020
A global research collaboration, led by world class institutions in Singapore, the UK and the USA, has developed the most detailed catalogue of mutational fingerprints found in most types of cancers that could help clarify their developmental history and lead to new prevention and treatment strategies.
04 Feb 2020
A multidisciplinary team of researchers at Japan's Tohoku University has found that a gene regulator, called BACH1, facilitates the spread of pancreatic cancer to other parts of the body. The scientists, who published their findings in the journal Cancer Research, say drugs that control BACH1 could improve disease prognosis.
31 Jan 2020
Looking for experts to who can comment on the current coronavirus outbreak? With the novel coronavirus outbreak happening now, we have prepared an abbreviated Focus On to help connect journalists with experts who are prepared to speak with international media about different aspects, including public health, virology, travel, tourism, economic impacts and spread of information.
29 Jan 2020
Hokkaido University scientists are getting closer to understanding how a rare hereditary disease impairs the skin’s barrier function, which determines how well the skin is protected.
24 Jan 2020
Looking for experts to who can comment on the current coronavirus outbreak? With the new coronavirus outbreak happening now, we have prepared an abbreviated Focus On to help connect journalists with virus experts who are prepared to speak with international media as the situation unfolds.
22 Jan 2020
Researchers at Tohoku University have developed a new type of smart contact lenses that can prevent dry eyes. The self-moisturising system, which is described in the journal Advanced Materials Technologies, maintains a layer of fluid between the contact lens and the eye using a novel mechanism.
Giants in history
Chinese biochemist Chi Che Wang (1894 - 1979), one of the first Chinese women to study abroad, advanced to prominent research positions at American institutions including the University of Chicago and the Northwestern University Medical School.
Ruby Sakae Hirose (1904 – 1960) was a Japanese-American scientist whose research contributed significantly to our understanding of blood clotting, allergies and cancer.
Flora Zaibun Majid ( 1939–2018) was an accomplished Bangladeshi researcher in botany and nutrition science and the first female chairperson of the Bangladesh Council of Scientific and Industrial Research.
Iranian physician and bacteriologist Azar Andami (8 December 1926 – 19 August 1984) developed a cholera vaccine to combat an outbreak that swept through the Middle East, India, Southeast Asia, and Africa in 1937.
Irene Ayako Uchida’s (8 April 1917 – 30 July 2013) strides to understand genetic diseases such as Down syndrome paved the way for early screening of chromosomal abnormalities in foetuses.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
Maggie Lim (5 January 1913 – November 1995) was a Singaporean physician who promoted family planning and expanded the access to clinics to improve the quality of life for mothers and children in Singapore’s early days.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
The founder of the Adyar Cancer Institute in India, Muthulakshmi Reddy (30 July 1886 – 22 July 1968), fought to uplift women and girls from impoverished situations.
Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Archana Sharma (16 February 1932 - 14 January 2008) conducted research into plant and human genetics that expanded the understanding of both botany and human health. In relation to botany, she uncovered the means by which asexually-reproducing plants evolve into new species.
The first Thai woman to receive a degree in medicine, Margaret Lin Xavier (29 May 1898 – 6 December 1932), is best remembered for her compassion towards her less privileged patients.
In 1915, pathologist Katsusaburo Yamagiwa and his research assistant Koichi Ichikawa became the first to prove that chronic exposure to chemicals can cause cancer.
Filipino chemist and pharmacist Manuel A. Zamora (29 March 1870 – 9 July 1929) is best remembered for his discovery of the tiki-tiki formula to combat beriberi, a disease caused by Vitamin B1 deficiency.
After witnessing death and suffering as a youth in his home village during World War II, Nguyễn Tài Thu (6 April 1931 – 14 February 2021) set his sights on alleviating pain by becoming a doctor. After studying Traditional Chinese Medicine in China in the 1950s, Thu returned to Vietnam to serve in military hospitals. Eventually, he became the country’s foremost practitioner of acupuncture, a technique he first learned by inserting needles into himself.
David T. Wong (born 1936) is a Hong Kong-born American neuroscientist who is best known for discovering the antidepressant drug fluoxetine, better known as Prozac.
Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
Hsien Wu (24 November 1893 – 8 August 1959) is widely regarded as the founder of biochemistry and nutrition science in China. He was the first to propose that protein denaturation was caused by the unfolding of the protein, instead of chemical alteration.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Syed Qasim Mehdi (13 February 1941 – 28 September 2016) was a Pakistani molecular biologist who was a founding member of the Human Genome Diversity Project (HGDP), which assessed human diversity by studying human migration, mutation rates, relationships between different populations, genes involved in height and selective pressure.
Tsai-Fan Yu (1911 – 2 March 2007) was a Chinese-American physician and researcher who was the first female full professor at Mount Sinai School of Medicine. She discovered that gout, a condition characterized by the painful inflammation of joints, was caused by elevated levels of uric acid in the bloodstream.
Min Chueh Chang (10 October 1908 – 5 June 1991) was a Chinese-American biologist who studied fertilization in mammalian reproduction.
A Japanese surgeon, Tetsuzo Akutsu (20 August 1922 – 9 August 2007) built the first artificial heart capable of keeping an animal alive.