Health

The authors discovered a shorter isoform of Rubicon called RUBCN100, which enhances autophagy in B cells.

The authors identified a structure in the circadian mRNA Period2 that affects the sleep-wake cycle. The results indicate how translation and post-transcriptional processes influence the body’s internal clock and its impact on sleep patterns.

Researchers led by Osaka University developed a novel genome editing technique known as NICER, which results in significantly fewer off-target mutations than CRISPR/Cas9 editing. The technique uses a different type of enzyme that makes single-stranded “nicks” in the DNA. Repair of these nicks is more efficient and accurate than repair of double-strand breaks caused by the current CRISPR/Cas9 editing. This technique represents a novel approach for the treatment of genetic diseases caused by heterozygous mutations.

Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are a previously unrecorded species of ant found in someone’s backyard, comparing traditional medicine to drugs for indigestion, and how breastfeeding can help babies develop a healthy gut.

- Initial research findings from the project led by the Korea Environmental Industry & Technology Institute, focused on “Advancing Island Wildlife Materials.” - Contributing to securing wildlife and constructing utility information big data.

A reanalysis of studies on night shift naps reveals the ideal snoozing schedule that may help combat fatigue and drowsiness when staying up all night.

Scientists have found that extracellular calcium mediates the activation of a membrane protein that waves the flag signalling cell death

Researchers have unveiled an intriguing phenomenon of cellular reprogramming in mature adult organs, shedding light on a novel mechanism of adaptive growth. The study, which was conducted on fruit flies (Drosophila), provides further insights into dedifferentiation - where specialized cells that have specific functions transform into less specialized, undifferentiated cells like stem cells.

Patients with a specific form of chronic indigestion react differently to images of food, compared to healthy control subjects or patients with irritable bowel syndrome.

In this collaborative project between Newcastle University and Universiti Malaysia Perlis (UniMAP), the team aimed to create a sustainable, cost-effective lower limb prosthetic socket (LLPS) using natural fiber-reinforced composites. The objectives included designing a green LLPS, assessing its environmental impact, and engaging stakeholders. Pineapple Leaf Fiber (PALF) was chosen for sustainability. The project has also inspired worldwide interest in sustainable LLPS development through a press release, receiving inquiries from students at Nanyang Technological University in Singapore and a group of 7th graders in the USA.

Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are a new species of fish that was spotted being sold at local markets, how humans almost went extinct, and an Earth-like planet that may be lurking in our solar system.

Capturing carbon dioxide, Shells go nuclear, Worms surf electric fields, Brain repair & Creating matter from light. Plus from our blog: Monitoring research for further impact. Read all in the latest Editor's Choice.

Researchers from Osaka University have revealed that the expression of a specific isoform of GREB1 Is4 is induced in malignant melanoma cells by the melanocyte-specific transcription factor, MITF. They revealed that GREB1 Is4 stimulates pyrimidine biosynthesis and promotes cancer cell proliferation. Furthermore, the anti-tumor effect of antisense nucleic acids against GREB1 showed a potential new modality for malignant melanoma.

In recent years, an emerging zoonotic pathogen called E. albertii, transmitted by wild animals such as raccoons, has garnered attention due to its remarkable similarities to several strains of Escherichia coli (E. coli), including O157, and its potential to cause severe illness, particularly in children. A research group at Osaka Metropolitan University has developed a novel culture medium that allows for the selective cultivation of E. albertii from raccoon fecal samples. This enabled the successful isolation of E. albertii even from samples with very low quantities of this bacterium. Their findings are expected to further elucidate the bacteriological characteristics of E. albertii and to contribute to the control of foodborne illnesses.

Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are the detection of a rare isotope of oxygen, converting waste coconut fibers into a flavoring compound, and a smart contact lens battery that can be powered by tears.

Roughly 10% of the proteins in our body rely on zinc. A group of researchers has unearthed the secrets behind a tiny but crucial protein that shuttles zinc ions within our bodies, offering a deeper understanding of how our cells maintain optimal health.

How much is adequate screen time for a child? It is the question at the forefront of many parents’ minds. Now, a recent cohort study has found that the amount of screen time spent by one-year-olds is associated with developmental delays.

It is the first local research and innovation platform enabling Primary Care Professionals from public and private healthcare to deliver stronger primary care and improve patients’ health outcomes

Osaka Metropolitan University researchers conducted a 5-year claims-based study of 655 non-frail or pre-frail older adults who were certified as having low care needs to investigate the relationship between the risk of frailty and two types of care services. The results showed that users of community-based adult care services had a 40% reduced risk of developing frailty compared to non-users. This suggests that utilizing appropriate support and services can prevent the progression of frailty.

Deepak Verma from Chulalongkorn University and his international team of researchers are exploring ways to enhance chitosan using techniques like adding photosensitizers, dendrimers, and chemical modifications. They also surveyed the use of chitosan nanoparticles for medical purposes, notably wound dressings.

Anti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor therapies, they halt tumor progression in mice models.

Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are vegan 3D printed calamari rings, 4 000-year-old ceramic pipes and ditches, and how swirling stars make some rethink how gravity works.

Japanese fossil forest found, AI finds a way to people’s hearts, Language diversity and child social development & Supplement for kidney disease. Plus Submissions open for Asia Research News 2024. Read all in the latest Editor's Choice.

Osaka Metropolitan University scientists have developed an AI model that accurately estimates a patient’s age, using chest radiographs of healthy individuals collected from multiple facilities. Furthermore, they found a positive relationship between differences in the AI-estimated and chronological ages and a variety of chronic diseases, such as hypertension, hyperuricemia, and chronic obstructive pulmonary disease. In the future, it is expected that AI biomarkers will be developed to predict life expectancy, estimate the severity of chronic diseases, and forecast surgery-related risks.

A research team co-led by City University of Hong Kong (CityU) and The University of Hong Kong (HKU) has recently made a significant advancement in spinal cord injury treatment by using genetically modified human neural stem cells (hNSCs). They found that specifically modulating a gene expression to a certain level in hNSCs can effectively promote reconstruction of damaged neural circuits and restore locomotor functions, offering great potential for new therapeutic opportunities for patients with spinal cord injury.

Innovators from 10 Countries Compete for the Coveted Advanced Healthcare and Life Sciences International Innovation Awards at MTE 2023

Greetings from JHSSR, Horizon is proud to announce the highly acclaimed publication of the latest issue of 2023, Vol. 5, Issue 1 (Jul. 2023). The issue is now live at the Journal’s webpage. You may explore our range of contributions within this Issue. Explore this issue, click the links below.

Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are particle pollution linked to antibiotic resistance and microplastics being found in the body, fossils that show a marine reptile that used filter feeding, and how a connection in our brains compares our rewards to ones that others received.

Researchers from Osaka University clarified the interactions of the proteins Tejas (Tej), Vasa (Vas), and Spindle-E (Spn-E) in the formation of cellular compartments known as nuage and the processing of PIWI-interacting RNA (piRNA) precursors in Drosophila melanogaster ovaries. piRNAs help prevent the transmission of genetic mutations through reproductive cells, and insight into the dynamics of piRNA formation and processing may contribute to our understanding of the mechanisms underlying reproductive disorders, including infertility.

- Collaborative study by Choi, Head of the DGIST Core Protein Resource Center, and Prof. Park from Kyungpook National University uncovers the alarming impact of secondary microplastics on human health! - Environmental model exposes harmful effects of naturally altered secondary microplastic production