Health

Focusing on the imperative of integrating science, policy and clinical practice to advance global One Health movement especially in the aftermath of COVID-19, the Congress will feature sharing by leading global scientists and policymakers on ways to address complex global health challenges.

Research in Singapore confirms a link between tiny particulates in air pollution and sudden cardiac arrests in the general population.

Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are jellyfish-like fossils, mythic diseases, and a transistor that can detect cancer cells.

As our brains develop, cells within it ‘eat’ neuronal elements to clear out debris, pathogens and help improve efficiency. A recent study showed that motor learning in mice helped enhance the engulfing of synapses by Bergmann glial cells. The discovery could have possible implications for explaining why synaptic shrinkage and loss occur in depression, schizophrenia, and Alzheimer’s disease.

Triple-negative breast cancer (TNBC) tumors gain immunosuppression and chemoresistance through interactions between interleukin 34 and myeloid-derived suppressor cells, researchers find.

A research group at Osaka Metropolitan University has developed a drug delivery system that activates a strong cellular immune response to attack cancer cells, using one-tenth of the amount of antigen needed in the group’s previous work. By incorporating positively charged cationic lipids into liposomes and adding negatively charged pH-responsive polysaccharides to the surface, the research group increased the uptake efficiency of liposomes encapsulating cancer antigens by dendritic cells by approximately five times, which increased cytokine production by about 100 times. This increased M1-type macrophages, which activate cancer immunity, and decreased M2-type macrophages, which promote cancer growth.

Call To Action urges G20 member countries and partners to mobilize adequate resources to close the TB funding gap and save lives.

Leading global scientists and policymakers will exchange learnings to promote multi-sectoral collaboration to address complex global health challenges

Asbestos is a toxic substance that is found in older buildings, as well as in cosmetics and products for children. As testing for its presence can be problematic, Hiroshima University Professor Akio Kuroda has been working on a novel solution.

Small neighboring galaxy filled with dark matter detected with gamma rays, How a virus induces heart inflammation, Shedding light on the happy hormone, Microfossils may hold key evolution clues. Read all in the October's Editor's Choice plus Upcoming event KNOWLEDGE MARKETPLACE – Bangkok 2022: Exchanging of ideas for a Democratic Myanmar.

Investigations in Japan have uncovered some molecular mechanisms behind mitochondrial dysfunction in chronic heart failure.

Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are scaling up production of a zombie fungus, the critical eye of female dogs, and enlightenment available on your smartphone.

Osaka Metropolitan University researchers interviewed active para-athletes with lower-limb disabilities who compete at an international level, about diet and nutrition. The research team found that what para-athletes considered an ideal diet was not necessarily optimized for improving athletic performance, and even when para-athletes understood diets geared towards athletic performance, characteristics of their disabilities impose barriers to implementing dietary changes. Understanding these concerns and struggles is important for nutritionists who support para-athletes in sports nutrition.

Osaka Metropolitan University researchers conducted a study of human mobility to find effective lifestyle changes that enable people to exist with the novel coronavirus COVID-19, while maintaining social and economic activities. They found that restricting the human mobility in specific areas according to the state of the pandemic, rather than uniformly controlling human mobility, could be effective in reducing the number of new COVID-19 infections.

When a cancer spreads, the invasion of tumor cells into the lymph nodes present various barriers to effective treatment. Harnessing a lymphatic drug delivery system, where drugs are injected directly into sentinel lymph nodes under ultrasound guidance, a collaborative research group has developed a novel drug formulation that enhances the therapeutic response of carboplatin, a commonly used chemotherapy medication.

Researchers develop a ground-breaking model to estimate bait vaccination effectiveness in wild animals based on the proportion of immunized animals in a population and the number of vaccine applications.

Researchers from Hokkaido University and Toppan have developed a method to detect build-up of amyloid β in the brain, a characteristic of Alzheimer’s disease, from biomarkers in blood samples.

Good hand hygiene has been found to be an effective way to prevent the spread of infectious organisms and the most important defence against disease, but studies have shown that many parents have inadequate knowledge, reporting skills, and parenting practices related to seasonal influenza. Previous research has shown a positive relationship between parents’ and children’s health practices. The research by Dr Peggy Or Pui-lai, Assistant Professor at the Department of Health and Physical Education, The Education University of Hong Kong, investigated whether there was any correlation between flu infection among parents and their kindergarten-age children, and the effectiveness of using hand hygiene interventions in kindergartens to lower kindergarten children’s absenteeism attributable to seasonal flu.

The National Health Innovation Centre, Singapore (NHIC) has launched a Clinical Innovation and Adoption Initiative to nurture promising healthtech projects for adoption and scaling across healthcare clusters in Singapore.

Researchers from Osaka University have developed a skin-like device to measure brain activity via electroencephalography, which uses electrodes to measure electrical activity on the scalp (reflecting underlying brain activity). The device has other useful applications, such as measuring heart rate and blood oxygen levels. Wearable devices that can remotely assess brain health in everyday settings are likely to improve healthcare for millions of people worldwide.

The Malaysia Technology Expo (MTE) 2022: SDG International Innovation Awards & Expo (SDGIIAE) returns for its 2nd edition and the awards encourage the development of innovative solutions for local and global challenges.

Giants in History: Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.

Vaccines have become the most important weapon in the fight against the COVID-19 pandemic, but antibody levels after vaccination decay quickly over time. Therefore, an accurate and affordable antibody rapid test is urgently needed to adjust the revaccination strategy. A research team led by City University of Hong Kong (CityU) recently invented an accurate rapid-testing device that can quantify and display the antibody level as a length of a visual bar, like a mercury thermometer, in as few as 20 minutes, enabling convenient mass screening or individual monitoring of immune protection against COVID-19.

- DGIST Professor Jin Ho Chang and Jae Youn Hwang's joint research team revealed for the first time in the world that the depth focused light can be increased by using a bubble layer temporarily created using ultrasound. - The collaborative research of ultrasound and optical imaging experts is expected to overcome the physical limitations of optical imaging and treatment depth.

Low concentrations of cetylpyridinium chloride, an antimicrobial agent present in mouthwashes, inhibit the infectivity of four variants of SARS-CoV-2.

Metastasis—when cancer spreads to form new tumors—causes approximately 90% of cancer-related deaths. Because metastatic cancer cells circulate in the blood, the liver—which filters the blood—is considered the most vulnerable organ, so treatments that prevent liver metastasis are urgently needed. A team of Osaka Metropolitan University researchers discovered a mechanism that allows metastatic cancer cells to infiltrate the liver, and how that infiltration can be blocked by inhibiting a related protein.

Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are an algorithm that can detect epilepsy from brain scans, the first National Robotics Tournament in Vietnam, and how being lonely or depressed can accelerate aging.

Research performed on human blastoids, a research model of an early embryo built out of stem cells, may allow scientists to understand better what causes birth defects and lost pregnancies, and so prevent them. But such research is also ethically fraught, warn bioethicists, due to differing beliefs on whether the blastoid possesses sentience or has the potential to do so.

Linked lanthanides shine light on crystal engineering, New technique reveals hidden genome, Red, white and blue alerts for dangerous bacteria & Windows gain competitive edge over global warming. Read all in the September's Editor's Choice plus this month's Asia Research News 2022 magazine pick - Floating sensors to gather ocean data.

A simple and economical method of detecting SARS-CoV-2 viral loads in wastewater with high sensitivity has been developed, expanding the use of wastewater-based epidemiology for tracking the virus in populations.