Bubbly idea: Ultrafine bubble showers suppress atopic dermatitis

Considerable positive results found in mice with skin condition induced by external factors

Ultrafine bubble showers and atopic dermatitis: The amount of inflamed skin showed a reduction in some mice with atopic dermatitis after undergoing treatment with regular and ultrafine bubble showers.

Bubble baths might be soothing soaks, but bubble showers could be the next thing in keeping the skin clean.

An Osaka Metropolitan University-led medical research team found that ultrafine bubble showers might help prevent atopic dermatitis.

Graduate School of Medicine student Ayaki Matsumoto and Associate Professor Hisayoshi Imanishi led the study into using ultrafine bubbles, often used to clean medical equipment, on mice with atopic dermatitis.

The scientists found that in mice with atopic dermatitis due to external factors, inflammation was markedly suppressed when the affected skin was showered with ultrafine bubbles, while normal showers also showed some positive results. Additionally, the ultrafine bubble showers improved the levels of proteins in the skin that act as a protective barrier. For mice with atopic dermatitis caused by genetic factors, however, there were no significant differences even compared to mice who were not showered.

“The results of this study suggest that ultrafine bubble shower treatment might be a new treatment for allergen-induced atopic dermatitis for humans, but this study was conducted on mice and the shower treatment period was short, only a week or two,” stated graduate student Matsumoto.

“From now on,” Professor Imanishi added, “it will be necessary to conduct ultrafine bubble shower therapy for several months on human patients to examine the effects.”

The findings were published in Frontiers in Immunology.

 

Conflict of interest

Author MH is employed by Science Co., Ltd. This research was conducted with a research fund from Osaka city and Science Co., Ltd. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Published: 21 Mar 2025

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Rina Matsuki

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Journal: Frontiers in Immunology
Title: Beneficial effects of ultrafine bubble shower on a mouse model of atopic dermatitis
DOI: 10.3389/fimmu.2024.1483000
Author(s): Ayaki Matsumoto, Hisayoshi Imanishi, Mika Yamanaka-Takaichi, Masateru Hirae, Daisuke Tsuruta and Kozo Nakai
Publication date: 26 December 2024
URL: https://doi.org/10.3389/fimmu.2024.1483000

Funding information:

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. The author(s) declare that financial support was received for the research from Osaka city.