Japan
News
30 Nov 2023
Aids local governments in adapting to the threats of climate change
29 Nov 2023
Researchers at Kanazawa University report in Science Advances how they can accelerate and decelerate chirality inversion in large cage molecules using alkali metal ion binding.
27 Nov 2023
A research team from Osaka Metropolitan University has successfully developed a novel pneumococcal vaccine by combining the team’s proprietary mucosal vaccine technology with pneumococcal surface proteins that can cover a wide range of serotypes. Experiments were conducted using mice and macaques and it was confirmed that pneumonia caused by pneumococcal infection was clearly suppressed in the target groups of animals inoculated with the vaccine.
27 Nov 2023
Researchers from Osaka University found that HSP47, a collagen-specific chaperone, is a key determinant of body fat levels. HSP47 expression levels are upregulated with obesity and greater food intake and decreased with fasting, exercise, calorie restriction, bariatric surgery, and wasting syndrome, suggesting that HSP47 modulation has a profound effect on fat storage.
22 Nov 2023
Osaka Metropolitan University researchers and their colleagues have successfully detected an ultra-high-energy cosmic ray with an energy level comparable to the most energetic cosmic ray ever observed. The cosmic ray is set to be named after the Japanese sun goddess, Amaterasu. No promising astronomical object has been identified in the direction from which this cosmic ray originated, implying the potential existence of unknown astronomical phenomena and novel physical origins beyond the Standard Model.
21 Nov 2023
Researchers from Osaka University have shown that lysosomes, key organelles for maintaining cellular stability, can be repaired once damaged by a process termed microautophagy. They identified molecules called STK38 and GABARAPs as key regulators of this process. Depletion of microautophagy regulators lead to increased cellular senescence and a shorter lifespan, indicating the importance of this process. This study is highly significant for the achievement of healthy aging and points toward new therapies for age-related diseases.
21 Nov 2023
Glass is a fundamental material. Yet its atomic structure still baffles scientists to this day. Researchers have developed a new way to quantify ring shapes in chemically bonded networks of glass, chipping away at some of the mysteries behind glass’s atomic structure.
21 Nov 2023
Researchers develop new method suppressing the distribution of drugs to healthy tissues, but also to rapidly removes the drugs once distributed in the body, which could improve the accuracy of imaging diagnosis of difficult cancers, reduce toxicity to healthy tissues, and furthermore improve the effectiveness of treatment.
21 Nov 2023
Out of this living laboratory emerged unexpected insights on coexistence from an “unusual” source.
20 Nov 2023
This paper highlights the underexplored potential of chiral self-sorting in the design of switchable and metastable discrete supramolecular structures.
17 Nov 2023
Researchers at Kanazawa University report in Nature Communications how they can control chirality inversion in α helical peptides.
17 Nov 2023
Rapid preparation and application of a panel of clinical antibodies armed with B-BiTE for refractory malignancies
17 Nov 2023
Researchers from Osaka University found that Japanese people who used medical information were more likely to wear masks and disinfect their hands even before the COVID-19 outbreak, while those who exchanged information with acquaintances were more likely to newly start mask-wearing and hand disinfection post outbreak. This will assist in the development of risk communication strategies to promote infection-preventive behavior in a timely manner.
14 Nov 2023
Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.
13 Nov 2023
Steel and aluminum are key players in supporting economic growth, yet materials joining them remain unexplored due to their fusion zones’ brittleness. A new 3D printing method’s fix may be a step toward a steel-aluminum hybrid renaissance.
10 Nov 2023
New insights on how individual immune responses to the SARS-CoV-2 virus, particularly in mutant strains, can influence the efficacy of COVID-19 vaccines
09 Nov 2023
A new study suggests that self-deception is the key to understanding irrational actions of national leaders in war, as exemplified by Vladimir Putin's invasion of Ukraine.
09 Nov 2023
Researchers at Kanazawa University report in Cancer Research how Kras and p53 mutations influence the tumor suppressor and promoter functions of a TGF- ß pathway. The findings may lead to a new approach for colorectal cancer therapy.
09 Nov 2023
A research team led by Osaka University used 125 physical markers to understand the detailed mechanics of 44 different human facial motions. The aim was to better understand how to convey emotions with artificial faces. Beyond helping with the design of robots and androids, this research can also benefit computer graphics, facial recognition, and medical diagnoses.
07 Nov 2023
Microscopes usually use backscattered radiation to create images, but a research group from the Institute of Industrial Science, The University of Tokyo, is developing an all-new method to study materials using the faint light they emit, generated by heat
06 Nov 2023
Researchers at the Institute of Industrial Science, The University of Tokyo study the quantum mechanical phenomenon known as vacuum fluctuations using a nanoscale hybrid device, which may lead to ultrasensitive quantum sensors or information processors.
02 Nov 2023
Future missions will be able to find signatures of violating the parity-symmetry in the cosmic microwave background polarization more accurately after a pair of researchers has managed to take into account the gravitational lensing effect, reports a new study in Physical Review D, selected as an Editors' Suggestion.
02 Nov 2023
A researcher from Osaka University has investigated the associations between mask usage and the reasons people give for wearing a mask. Online surveys were conducted before and after policies that downgraded the status of COVID-19. The study found that 59% of respondents continued wearing masks even after policy changes. Several sociological and psychological reasons other than disease prevention for mask usage were identified.
01 Nov 2023
Osaka University and NEC Corporation are jointly developing a data infrastructure called RED-ONION to accelerate open science by reducing the burden on researchers to record the research process, share research data and publish them on the data aggregation platform. They are currently engaged in the R & D of three elemental technologies: (1) Technology to integrate a data aggregation platform and data publication platform, (2) Technology to generate research process information on supercomputers, and (3) A high-speed data transmission function. These research results will be showcased at the International Conference for High Performance Computing, Networking, Storage, and Analysis (SC23) scheduled to be held from November 12 to 17, 2023 in Denver, Colorado.
27 Oct 2023
Researchers at Kanazawa University report in the Journal of Physical Chemistry Letters high-speed atomic force microscopy studies that shed light on the possible role of the open reading frame 6 (ORF6) protein COVID19 symptoms.
27 Oct 2023
To quickly and accurately characterize prospective materials for use in solar energy, researchers built an automated system to perform laboratory experiments and used machine learning to help analyze the data they recorded. Their goal is to identify semiconductor materials for use in photovoltaic solar energy, which are highly efficient and have low toxicity.
26 Oct 2023
Research out of Osaka University finds an overlap in the mechanism of hair color determination and bone resorption, which is associated with bone related diseases like osteoporosis. The findings revealed that proteins named Rab32 and Rab38 play pivotal roles in bone resorption in osteoclast, cell specialized in the process. These proteins are also crucial for pigmentation of hair and skins.
26 Oct 2023
Research from Osaka University demonstrates a nanopore-based technique that can detect different variants of SARS-CoV-2, the virus that causes COVID-19. The method was very effective in detecting the Omicron variant of the virus in the saliva of people with COVID-19.
25 Oct 2023
Pair-bonded Java sparrows show enlarged eye rings to signal breeding readiness.
Events

24 Oct 2023
This Forum will take place on 24 October 2023 in Kobe, Japan. It will be held in hybrid format (on-site and virtual).
21 Nov 2023
Japan Scicom Forum brings together communicators, writers, scientists and journalists in Japan. Registration is free and the event will be in English.

11 Oct 2023
Meet your potential business partners in this Partnering Event. Asia's Largest Partnering will be held in both digitally and physically.

23 Dec 2022
This Forum will take place on 23rd December 2022 in Kobe, Japan. It will be held in hybrid format (on-site and on-line).

19 Sep 2022
The Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University will hold a ‘Workshop on Computational Biophysics of Atomic Force Microscopy – A Lecture Course Approach’ 19-21 September 2022, online.

01 Mar 2022
The Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University will hold their 5th NanoLSI Symposium 1-2 March 2022, online.
13 Feb 2022
A joint forum by APN, ADRC, JICA Kansai, and Graduate School of Disaster Resilience and Governance, University of Hyogo
26 Jan 2022
Since 2001, the "nano tech" exhibition is one of largest exhibition in the world held in Tokyo, Japan. In 2022, it will be held in On-site and On-line format as a Hybrid event.
09 Sep 2021
Tohoku University will be hosting the 8th German-Japanese (HeKKSaGOn) University Presidents' Conference from Sept 9-10. The online event includes an Academic Conference on the first day that is open to the general public. See article for details.
09 Sep 2021
Earth-Life Science Institute (ELSI) will launch a new Master-PhD course on origin-of-life science and astrobiology at Tokyo Institute of Technology. The five-year ELSI course is open for domestic and international students who wish to tackle fundamental questions in natural science such as the origin and evolution of living planets. ELSI will provide financial support (as salary of a research assistant) for all the students, except for ones who are going to be supported by JSPS DC fellowships (Japan) or equivalent fellowships.
12 Oct 2021
The Asia's Largest Partnering “BioJapan” will be held both digitally and physically. Meet your potential business partners in this Partnering Event!
14 Jul 2021
Intelligent Mobility 2021 will offer a platform for industry experts, thought leaders, policy makers, city planners and researchers to discuss the future of mobility, growth opportunities emerging as a result of disruptive innovation, and the potential impact of new business models.
10 Mar 2021
Upcoming side event at the 7th Asia-Pacific Climate Change Adaptation Forum: Partnerships to harmonize science information and knowledge at regional scales for enabling adaptation

26 Mar 2021
Springer Nature and the University of Tokyo to hold SDGs Symposium 2021, “Interdisciplinary science solutions for food, water, climate and ecosystems Sustainable Development Goals”

09 Mar 2021
The SciREX Open Forum’s 10th session will invite Dr. Yoichiro Matsumoto who assumed the position of the 2nd S&T Advisor to Japan's Minister of Foreign Affairs as a speaker to talk about what we can see from the pandemic, how S&T Diplomacy should be in the ongoing pandemic, and what actually can be done.
24 Feb 2021
INTERPHEX Week Osaka is Asia's leading exhibition for pharmaceutical industry, consists of 2 exhibitions for pharmaceutical technologies - INTERPHEX OSAKA (Manufacturing & Packaging) and PharmaLab Expo OSAKA (Pharma R&D and Drug Discovery).
09 Dec 2020
The 20th International Nanotechnology Exhibition & Conference will be held in onsite-online hybrid format.
25 Nov 2020
Asia's Leading Pharma & Bio Tech Show will be held as scheduled from November 25-27, 2020 at Makuhari Messe, Japan. It will be held both on-site and online.
10 Jul 2020
Tohoku University is hosting an online lecture on COVID-19 on July 10. Led by top virologist Hitoshi Oshitani, the panel will share the latest on the pandemic, and discuss how history, culture and religion can help us understand the challenges ahead.
04 Jul 2020
Tohoku University's Graduate School of Education is hosting a three-part webinar series on how the COVID-19 pandemic is transforming education in the Asia-Pacific region. The event is in English and open to everyone. But spots are limited and registration is required.
Details: https://bit.ly/2MT2UFA
14 Oct 2020
Asia's Premier Partnering Event for the Global Biotechnology Industry. This year’s exhibition will be held as originally planned at Pacifico Yokohama. BioJapan partnering is available both physically and virtually. Plus some seminars will be available online.

17 Aug 2020
The Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, is calling for participants for 9th Bio-SPM Summer School (previously known as Bio-AFM Summer School)).
19 Mar 2020
Institute for the Advanced Study of Human Biology(ASHBi) holds the annual symposium with twenty-one speakers who are leading human biology including human development, genetics, and evolution.
26 Feb 2020
Japan's Leading Exhibition for Pharmaceutical R&D and Manufacturing Technologies!

22 Apr 2019
Tohoku University will host a closed door stakeholder’s meeting on April 21, followed by the inaugural International forum on next-generation synchrotron radiation on April 22.

24 Mar 2019
The Tohoku University Center for Innovative Integrated Electronic Systems (CIES) will host its fifth technology forum in Tokyo from March 24~26.
14 Nov 2019
The goal of this conference is to address the emerging technologies and themes in Microfluidics, Lab-on-a-Chip and Organ-on-a-Chip fields as these areas are expanding and evolving.
11 Nov 2019
The conference addresses the whole ecosystem of Cell & Gene Therapy and 3D-Bioprinting with a focus on 3D-Culture, Organoids, Bioprinting and Technology Platforms being developed to bring cell therapy, gene therapy and regenerative medicine to the clinic.
Researchers
I am a japanese physician-scientist in gastroenterology, especially in neurogastroenterology.
Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU)
Ken’ichi Nomoto is a visiting senior scientist at Kavli IPMU and Professor Emeritus at The University of Tokyo. He is one of the best experts in the world in astronomy and astrophysics, particularly on stellar evolution and supernovae. He was awarded the Order of the Sacred Treasure by the Japanese government in 2020.
Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU)
Jia Liu is the Director of the Center for Data-Driven Discovery and associate professor at CMB Group at Kavli IPMU. Her research integrates data science techniques in the study of large-scale structures of the universe (dark matter, halos, filaments, voids).
Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU)
Elisa Ferreira is Assistant Professor at the Kavli IPMU and at the Institute of Physics of the University of São Paulo. Her research deals with the interface between cosmology, astrophysics, and high energy physics, focusing mostly on dark energy and dark matter.
Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU)
Man Wai Cheung is a Project Researcher and the first Chien-Shiung Wu Prize Postdoctoral Fellow at KAVLI Institute for the Physics and Mathematics of the Universe (Kavli IPMU). Her research lies in the interplay between algebraic geometry, combinatorics and representation theory.
Hokkaido University
Dr. Eisuke Hasegawa is an Associate Professor at the Graduate School of Agriculture, Hokkaido University, where he heads the Animal Ecology Laboratory. His research interests include animal ecology; evolutionary biology; natural selection; sociality; and ethology.
Dr. Yukio Yasui is an Associate Professor at Kagawa University. He has dedicated his research work to ecology, ethology and evolutionary biology studies, with his more recent work on the evolution of sex.
National Institute for Materials Science (NIMS)
Dr Naoka Nagamura is senior researcher at the National Institute for Materials Science (NIMS) and visiting associate professor at Tokyo University of Science. She researches advanced materials, electrochemistry and photoemission spectroscopy.
Dr. Hiroki Ago is a Distinguished Professor of the Global Innovation Center at Kyushu University. His research focuses on nanomaterials, particularly graphene and related 2D materials, and their applications.
Tohoku University
Prof. Hiroshi Yabu is a Professor and Principal Investigator at the Advanced Institute for Materials Research (WPI-AIMR) at Tohoku University. His research interests include self-organization, biomimetics, and bio-inspired materials for energy and low environmental impacts.
Hokkaido University
Dr. Akira Kakugo is an Associate Professor at Hokkaido University. He has researched biomolecular motors and swarming of active matters.
Kyoto University
Dr. So Iwata is a Professor at the Graduate School of Medicine Kyoto University and the Group Director of the SACLA Science Research Group, RIKEN SPring-8 Center. He has investigated how specialized membrane channels remove antimicrobial drugs from inside bacterial cells.
Her current research focuses on the synthesis of semiconducting polymers for organic electronics and has published >100 papers in this area of research.
Assistant Professor Izumi Fukunaga grew up in Japan and Malaysia and went to London to study neuroscience. Her research focuses on how sensory circuits in the brain function.
Professor Gail Tripp is a neurobiologist who established the OIST Children’s Research Center to undertake research on the nature, etiology and management of ADHD with English and Japanese speaking children and families.
Assistant Professsor Lauren Sallan is a fish paleobiologist who uses big data — the fossil record — to study how some species win and others lose. Her multiple TED Talks on the evolution of fishes, mass extinction and paleontology have received over 3 million views.
Professor Shinya Maenosono leads his research group at Japan Advanced Institute of Science and Technology (JAIST). His research in JAIST has focused on two main areas of interest in the field of materials chemistry and nanotechnology. The first area involved wet chemical synthesis of semiconductor nanoparticles with controlled size, shape and composition for energy conversion device applications. The second area has focused on the synthesis and bioapplication development of monometallic and alloyed multimetallic nanoparticles.
Osaka City University
Prof. Shigekawa's research interest includes fabrication of heterointerfaces and advanced hybrid semiconductor devices such as multijunction solar cells and heterojunction bipolar transistors using surface activated bonding and their characterization.
National Institute for Materials Science (NIMS)
Ken-ichi Uchida is a group leader in the Spin Caloritronics Group, Research Center for Magnetic and Spintronic Materials under the National Institute for Materials Science (NIMS), Japan
National Institute for Materials Science (NIMS)
Satoshi Ishii is a principal researcher at International Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), Japan. He also holds an adjunct associate professorship at University of Tsukuba.
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
Hiroshi Kageyama is a professor in the Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Japan.
Earth-Life Science Institute (ELSI), Tokyo Institute of Technology
Mayuko Nakagawa is a biochemist at Earth-Life Science Institute (ELSI) based at the Tokyo Institute of Technology, Japan.
Hitoshi Gomi is an Earth scientist at Earth-Life Science Institute (ELSI) based at the Tokyo Institute of Technology, Japan.
Earth-Life Science Institute (ELSI), Tokyo Institute of Technology
Tomohiro Mochizuki is a specially-appointed assistant professor at Earth-Life Science Institute (ELSI) - Tokyo Institute of Technology.
Earth-Life Science Institute (ELSI), Tokyo Institute of Technology
Tony Z. Jia is a researcher at Japan’s Earth-Life Science Institute (ELSI), based at the Tokyo Institute of Technology. His research focuses on astrobiology, prebiotic chemistry, and origins of life.
Hokkaido University
Takeshi Horinouchi is a professor at the Faculty of Environmental Earth Science, Hokkaido University, Japan.
Assoc Prof Yuki Nagao is a materials scientist at the School of Materials Science, Japan Advanced Institute of Science and Technology.
Giants in history
Ruby Sakae Hirose (1904 – 1960) was a Japanese-American scientist whose research contributed significantly to our understanding of blood clotting, allergies and cancer.
Haisako Koyama (1916 – 1997) was a Japanese solar observer whose dedication to recording sunspots – cooler parts of the sun’s surface that appear dark – produced a sunspot record of historic importance.
Michiaki Takahashi (17 February 1928 – 16 December 2013) was a Japanese virologist who developed the first chickenpox vaccine.
Toshiko Yuasa (11 December 1909 – 1 February 1980) was the first Japanese female physicist whose research on radioactivity shed light on beta decay – the process in which an atom emits a beta particle (electron) and turns into a different element.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
In 1915, pathologist Katsusaburo Yamagiwa and his research assistant Koichi Ichikawa became the first to prove that chronic exposure to chemicals can cause cancer.
In 1915, Koichi Ichikawa along with pathologist Katsusaburo Yamagiwa became the first to prove that chronic exposure to chemicals can cause cancer.
Reiji Okazaki (8 October 1930 – 1 August 1975) and Tsuneko (7 June 1933) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.
Tsuneko (7 June 1933) and Reiji Okazaki (8 October 1930 – 1 August 1975) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
Hideki Yukawa (23 January 1907 – 8 September 1981) was awarded the Nobel Prize in Physics in 1949 for predicting the existence of the pi meson subatomic particle. Japan’s first Nobel laureate, Yakawa also expressed his support for nuclear disarmament by signing the Russell–Einstein Manifesto in 1955.
Shinichiro Tomonaga (31 March 1906 – 8 July 1979), together with Richard Feynman and Julian Schwinger, was awarded the Nobel Prize in Physics in 1965, for their contributions to advance the field of quantum electrodynamics. Tomonaga was also a strong proponent of peace, who actively campaigned against the proliferation of nuclear weapons and promoted the peaceful use of nuclear energy.
Japanese chemist Kenichi Fukui (4 October 1918 – 9 January 1998) was the first Asian scientist to be awarded the Nobel Prize in Chemistry. Together with Roald Hoffman, he received this honour in 1981 for his independent research into the mechanisms of chemical reactions.
Minoru Shirota (April 23, 1899 – March 10, 1982) was a Japanese microbiologist who invented the popular fermented drink Yakult.
Japanese physicist Ukichiro Nakaya (1900-1962) made the world’s first artificial snowflakes. He started his research on snow crystals in the early 1930s at Hokkaido University, where there is an unlimited supply of natural snow in winter. By taking over 3,000 photographs, he established a classification of natural snow crystals and described their relationship with weather conditions.
The techniques that make industrial pearl culturing possible were developed over a century ago at the Misaki Marine Biological Station in Japan. The station’s first director, Professor Kakichi Mitsukuri, emphasized to Kokichi Mikimoto in 1890 that stimulating pearl sac formation was important for pearl growth, and they went on to successfully develop methods for culturing pearls.
The field of solid-state ionics originated in Europe, but Takehiko Takahashi of Nagoya University in Japan was the first to coin the term ‘solid ionics’ in 1967. ‘Solid-state ionics’ first appeared in 1971 in another of his papers, and was likely a play on ‘solid-state electronics’, another rapidly growing field at the time.
Chika Kuroda (24 March 1884 – 8 November 1968) was a Japanese chemist whose research focussed on the structures of natural pigments.
Motoo Kimura (13 November 1924 – 13 November 1994) was a Japanese theoretical population geneticist who is best remembered for developing the neutral theory of molecular evolution.
Osamu Shimomura (27 August 1928 – 19 October 2018) was a Japanese organic chemist and marine biologist who dedicated his career to understanding how organisms emitted light.
Kikunae Ikeda (8 October 1864 – 3 May 1936) was a Japanese chemist who discovered the fifth basic taste, umami.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Kono Yasui (16 February 1880 – 24 March 1971) was a Japanese botanist who researched the genetics of poppies, corn and spiderworts and surveyed the plants that had been affected by the nuclear fallout after the atomic bombings of Hiroshima and Nagasaki.
Hitoshi Kihara (1893 – 1986) was one of the most famous Japanese geneticists of the 20th century. One of his most significant contributions was identifying sex chromosomes (X and Y) in flowering plants.
Michiyo Tsujimura (17 September 1888 – 1 June 1969) was a Japanese agricultural scientist and biochemist recognized for her research of green tea components.
A Japanese surgeon, Tetsuzo Akutsu (20 August 1922 – 9 August 2007) built the first artificial heart capable of keeping an animal alive.
Ogino Ginko (3 March 1851 – 23 June 1913) was the first registered female doctor to practise modern medicine in Japan.
Japanese geochemist Katsuko Saruhashi developed the first method and tools for measuring carbon dioxide in seawater