17 May 2024
Researchers from Osaka University found that the tyrosine kinase Csk plays a crucial role in regulating germinal center B cell signaling. Csk deletion in a mouse model led to increased ROS production and apoptosis, thereby inhibiting B cell affinity maturation.
Model of stable configuration of nitrogen and titanium in steel of iron-titanium alloy
16 May 2024
Calculations consider how a dozen metals such as titanium combine with nitrogen or carbon to form bonds
16 May 2024
Researchers at the Institute of Industrial Science, The University of Tokyo, enhance land surface maps to identify sloping landscapes in which vegetation changes are associated with slight elevation and water gradients.
Persimmon tannin powder
15 May 2024
Naturally derived antioxidants improve growth of yeast strain in presence of ethanol
As the observation interval lengthens—akin to slowing down a camera’s shutter speed—the dances of the molecules overlap and emerge as a blur of frequent changes, masking the intricate ballet of atoms in motion. (Illustration: Yumi Teruya)
15 May 2024
New research employs shutter speed analogies to validate 55-year-old theory about chemical reaction rates.
Zinc Finger Nucleases
14 May 2024
Genome editing is making inroads into biomedical research and medicine. By employing biomolecule modeling tools, a Japanese research team is accelerating the pace and cutting the cost of zinc finger nuclease (ZFN) technology, a primary gene editing tool.
Graphical abstract: Health Expenditure Impact of Opening a New Public Transport Station: A Natural Experiment of JR-Sojiji Station in Japan
13 May 2024
Time series data and causal impact algorithm reveal the effectiveness of a new transit station over a four-year period
10 May 2024
Researchers from Osaka University have used a novel combination of short-read and long-read RNA sequencing to identify the different isoforms of genes expressed in the crustacean Daphnia magna. Males and females are genetically identical, but using this technique the team revealed genes that switch the predominant isoform in a sex-dependent manner. This study contributes to our understanding of Daphnia’s sexual dimorphism and helps further advance technologies in crustacean aquaculture.
09 May 2024
Researchers at The University of Tokyo demonstrate enhanced radiative heat transfer across a gap between two micro-sized silicon plates by coating them with a layer of silicon dioxide, which may significantly improve heat management of computers.
07 May 2024
Researchers from Osaka University developed an in silico library comprising 54 potential triarylborane catalysts for the functionalization of amino acids and peptides with molecular hydrogen as a reductant. This library, together with chemometric machine learning, was used to identify the best candidates. Based on this process, an optimal catalyst was identified and found to promote the alkylation of aniline derivatives with exceptional functional group tolerance and produce only water as a coproduct.
Lithium-superrich iron oxides for cost-effective, high-capacity, and cyclable cathodes. (Illustration: Science Graphics. Co., Ltd. with modification)
02 May 2024
Charge-recharge cycling of lithium-superrich iron oxide, a cost-effective and high-capacity cathode for new-generation lithium-ion batteries, can be greatly improved by doping with readily available mineral elements.
02 May 2024
Osaka University researchers discovered a concerning association between bacteremia and probiotic use, particularly with Clostridium butyricum (C. butyricum) MIYAIRI 588. Whole-genome sequencing revealed that all C. butyricum bacteremia strains were probiotic derivatives. Out of 6,576 cases of positive blood cultures, C. butyricum was detected in only five cases, all derived from probiotics. The study underscores rare but serious adverse events linked to probiotics, advocating cautious prescribing practices, especially for hospitalized patients.
Figure. Exploring the effect of H2O2 eustress at single-cell level using hopping probe scanning ion conductance microscopy
01 May 2024
In a recent study published in the multidisciplinary academic journal Science Bulletin, a semi-monthly high-caliber peer-reviewed research outlet covering a broad range of natural sciences and high-tech fields, researchers from the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University utilized hopping probe scanning ion conductance microscopy (HPICM) and highly sensitive platinum-functionalized nanoelectrodes to conduct an in-depth investigation of the dynamic response of individual living colorectal cancer Caco-2 cells to changes in intracellular and extracellular hydrogen peroxide (H2O2) gradients, specifically focusing on eustress, at the single-cell level and in real-time. Their findings hold promise for innovative therapies against cancer and H2O2-related inflammatory diseases.
01 May 2024
Researchers from Osaka University have found that a brain disorder associated with flu (influenza-associated encephalopathy, or IAE) can be caused by the influenza virus entering the brain from the blood via endothelial cells. In these cells, the researchers observed viral protein accumulation, suggesting that antivirals targeting viral transcription/translation may be useful treatments for some patients. Given the lack of effective treatments for IAE, this finding will likely improve patient care and reduce IAE-related deaths worldwide.
 The new species of Japanese lily Lilium pacificum
01 May 2024
Classification of these plants bloom to double the number of taxonomic groups through morphological study, DNA analysis
(Illustration: Yuki Kimura)
29 Apr 2024
Samples reveal evidence of changes experienced by the surface of asteroid Ryugu, some probably due to micrometeoroid bombardment.
The flow-type fixed-bed reactor used in the process of recovering phosphorus from incinerated sewage sludge. (Photo: Naoto Tsubouchi)
26 Apr 2024
Chemical and heat treatment of sewage sludge can recover phosphorus in a process that could help address the problem of diminishing supplies of phosphorus ores.
26 Apr 2024
Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University report in Nano Letters how the use of high-speed atomic force microscopy helps to understand the crucial role played by certain biomolecules in DNA wrapping dynamics.
25 Apr 2024
Osaka University researchers discovered liver resident macrophages' pivotal role in defending against gut bacteria and related substances entering via the portal vein, particularly under compromised intestinal barrier conditions. Identified as "sentinel macrophages," they are activated by isoallo-lithocholic acid. This finding holds promise for developing preventive and therapeutic strategies for liver chronic inflammatory diseases, such as metabolic dysfunction-associated steatohepatitis (MASH), by enhancing the function of these macrophages to mitigate inflammation and improve treatment efficacy.
Estimated mortality and economic impacts of enhanced Siberian wildfires through air pollution for selected East Asian countries and Russian administrative districts under the present climate condition with the most extreme wildfire scenario estimated by the modeling. (Teppei J. Yasunari, et al. Earth’s Future. April 24, 2024)
24 Apr 2024
As wildfires in Siberia become more common, global climate modeling estimates significant impacts on climate, air quality, health, and economies in East Asia and across the northern hemisphere.
24 Apr 2024
Researchers from Osaka University examined how specific types of contextual changes, such as government recommendations and perceived behavior of others, influenced mask-wearing behavior during the COVID-19 pandemic. They found a complex relationship between societal norms and individual behavior during the pandemic, indicating that future strategies for public health crises interventions should consider various factors and contexts, including cultural predispositions.
23 Apr 2024
Using neutron scattering and voltage measurements, a group of researchers have discovered that a material's magnetic properties can predict spin current changes with temperature. The finding is a major breakthrough in the field of spintronics.
Native bacteria metabolize sweat in the armpits, causing odor to arise.
22 Apr 2024
Bacteriophage therapy could be developed based on study’s results
Watching over with minimal intervention is a hallmark of early childhood education in Japan.
19 Apr 2024
Watching and waiting with minimal intervention forms educational philosophy guided by balance
17 Apr 2024
Electron spin states can now be probed at much higher resolution and more efficiently, opening new opportunities in materials analysis and data processing technologies.
17 Apr 2024
Researchers from Osaka University used structured light and switchable fluorescent molecules to reduce the background light from the out-of-plane regions of microscope samples. This method allowed for the acquisition of images that surpassed the conventional resolution limit, and it may be useful for further study of cell clusters and other biological systems.
Effect of plasma irradiation on broken bone
16 Apr 2024
Aiming to reduce fracture recovery times, an Osaka Metropolitan University-led research group is focusing on plasma irradiation as a treatment method
To pass or not to pass?
16 Apr 2024
Skilled players show stronger inhibition processes when electing not to pass the ball
15 Apr 2024
Researchers from Osaka University found that a new activator called L687 induces cancer cells to accept delivery of antisense oligonucleotide (ASO) drugs. These drugs can treat cancer by blocking the transfer of messages from genes that encourage cancer growth. Previous methods to deliver ASOs into cells had only limited success. This research will help accelerate the development and delivery of novel ASO cancer therapies.
12 Apr 2024
Researchers from Osaka University and collaborating partners have synthesized triarylborane (TAB) compounds that exhibit unusual optical responses upon binding to certain anions. They also synthesized thin polymer films that incorporate the TAB and retain the sensing as well as the light emission properties of the TAB. This work is an important advance in plastic research and has applications in analyte sensing as well as electronic display technologies.


03 Jul 2019
Asia's leading pharma industry event
09 Oct 2019
Asia's Premier Partnering Event for the Global Biotechnology Industry
05 Mar 2019
Accelerate your pathway to partnerships in Asia
28 Feb 2019
The Nagoya Medal Award is awarded every year to two organic chemists who have made significant original contributions to the field. This year’s Gold Medal will be presented to Professor David W. W. MacMillan (Princeton University, USA), and the Silver Medal will be presented to Professor Chihaya Adachi (Kyushu University, Japan).
04 Oct 2018
ISTbM-6 with the 14th Hirata Award and the 4th Tsuneko and Reiji Okazaki Award.
10 Jun 2018
The Kavli IPMU invites you gain insight into how physics predicts our Universe may exist alongside an infinite number of other universes, and how philosophy suggests the world as we know it may not exist at all.
22 Dec 2017
The Nagoya Medal Award is awarded every year to two organic chemists who have made significant original contributions to the field. This year’s Gold Medal will be presented to Prof. “Bert” Meijer (Eindhoven University of Technology, Netherlands), and the Silver Medal will be presented to Prof. Hiroaki Suga (The University of Tokyo, Japan).
20 Nov 2017
ISTbM-5 with the 13th Hirata Award and the 3rd Tsuneko and Reiji Okazaki Award
03 Aug 2017
The International ERATO Itami Molecular Nanocarbon Symposium 2017 will be held on August 3-4, 2017 at Nagoya University, Japan. This symposium will focus on recent achievements in the synthesis, utilization, and analysis of structurally well-defined nanocarbons and related materials.
27 Jan 2017
The Nagoya Medal Award is awarded every year to two organic chemists who have made significant original contributions to the field. This year’s Gold Medal is awarded to Professor Stephen Buchwald of MIT (USA) and the Silver Medal is awarded to Professor Masaya Sawamura of Hokkaido University (Japan).
12 Dec 2016
ISTbM-4 with the 12th Hirata Award and the 2nd Tsuneko and Reiji Okazaki Award
17 Oct 2016
This symposium will highlight research and education for the creation of a healthy society toward the achievement of United Nations Sustainable Development Goals (SDGs). The lectures and discussions cover the themes including the promotion of safe water environments, hazardous material elimination, and mother-and-child health.
27 Jul 2016
This year, we will hold its second symposium to further seek novel molecules and materials for dissecting and controlling mechano-nanoarchitectonics of life. Presentations in the symposium are made by a wide variety of speakers from material science, sensors and actuators, mechanochemistry, interfacial sciences, and of course biology.
26 Jun 2016
On behalf of the ISEE-ISES AC2016 Sapporo organizing committees, it is great pleasure to welcome you to the 5th ISEE Asia Chapter and the first joint symposium of ISEE and ISES, Asia chapter. The program theme is “Environment, Health, and Sustainable Society” and will be held in Sapporo, Hokkaido, Japan on June 26-29th, 2016.
13 Jun 2016
The First International Symposium on Advanced Soft Matter: Celebrating the Kick-off of the Global Station for Soft Matter, GI-CoRE, Hokkaido University, Japan.
22 Jan 2016
The Nagoya Medal Award is awarded every year to two organic chemists who have made significant original contributions to the field. This year’s Gold Medal is awarded to Professor Stuart Schreiber of the HHMI, Broad Institute of MIT & Harvard, Harvard University, USA and the Silver Medal is awarded to Professor Zhaomin Hou of RIKEN, Japan.
25 May 2015
This international symposium brings together world-class scientists in biology and chemistry, including, Dr. Ashraf Brik (Technion-Israel Institute of Technology, Israel) and Dr. Feng Zhang (Broad Institute of MIT and Harvard, USA).
21 Oct 2014
GREEN Open Seminar will be held on 21st October, 2014, to have a lecture by Dr. Hiroaki Benten, Assistant Professor, Department of Polymer Chemistry, Kyoto University.
27 Oct 2014
The Nagoya Medal Award is awarded every year to two organic chemists who have made significant original contributions to the field. This year’s Gold Medal is awarded to Professor John F. Hartwig of the University of California, Berkeley, USA and the Silver Medal is awarded to Prof. Itaru Hamachi of Kyoto University, Japan.
12 May 2014
The 2nd International Symposium on Transformative Bio-Molecules 2014 is an annual event held by the ITbM, inviting prestigious speakers from around the world to enhance interdisciplinary research between molecular synthetic chemistry and plant biology.
01 Jul 2013
NIMS Conference 2013 will be discussing the latest innovations in nano electronics. Registration deadline is June 23 and abstract submission deadline is May 17.
15 Nov 2012
The Irago Conference 2012 (Asia-Pacific Interdisciplinary Research Conference 2012) will be held November 15-16, 2012 in Irago, Aichi prefecture, Japan.
04 Jun 2012
National Institute for Materials Science (NIMS) is pleased to announce “NIMS Conference 2012” to be held from June 4 to 6 2012. The theme is “Structural Materials Science and Strategy for Sustainability - Back to the Basics“
29 Feb 2012
The MANA International Symposium, jointly held with International Center for Young Scientist (ICYS) is organized once a year to disseminate the research results of MANA and ICYS to a wide audience.
17 Feb 2012
In this symposium, advancement of R & D especially on renewable electrical energy sources and structural materials for seismic safety using nanotechnology will be reviewed.
17 Nov 2011
This conference provides an ‘interdisciplinary-platform’ to enhance mutual understanding between scientists, engineers, policy makers, and experts from a wide spectrum of pure and applied sciences in order to resolve the daunting global issues facing mankind.
17 Oct 2011
This Conference focus on the development in micro and nanotechnologies. It will take place at Hotel Sinaia in Romania from 17th to 20th October 2011.
15 Sep 2011
SIBCON-2011 is the leading Conference in Siberia for learning the latest development on control systems, compound semiconductors, RF devices and microwave circuit applications.
19 Sep 2011
The ASAM-3 is organised by Kyushu University for interdisciplinary discussion between scientists from Asian universities, research institutions and companies on chemistry, physics and biology of advanced materials. Deadline for Early Registration is August 1, 2011


National Institute for Materials Science (NIMS)
Dr Ryota Tamate is a materials scientist at the Center for Green Research on Energy and Environmental Materials, National Institute for Materials Science, Japan.
Nagoya University
Yukikazu Takeoka is a materials engineer at the Department of Molecular Design & Engineering at Nagoya University, Japan.
Hokkaido University
Daisuke Hirano is an assistant professor at the Ocean and Sea Ice Dynamics Group, the Institute of Low Temperature Science of Hokkaido University, Japan.
Hokkaido University
Jorge García Molinos is an aquatic ecologist broadly interested in global change ecology and macroecology.
I am a sociologist studying domestic violence and sexual violence situations and measures in Japan, and am the director of two NGOs, All Japan Women’s Shelter Network and Rape Crisis Center in Hiroshima. As an NGO activist, we, All Japan Women’s Shelter Network, submitted “The Request for the Prevention of DV and Child Abuse under the Condition of Novel Coronavirus Countermeasures” to the Japanese government on March 30. This letter of request drew more attention than we expected, and many newspapers and TV quickly covered the issue. A lot of people have talked about this online. The prime minister and minister of gender equality have since addressed the issue in statements, and the Cabinet has approved emergency funding for expanded consultation services.
Picture of Yuka Jibiki
As a young research practitioner, I’ve been working with more than 1,000 female college students who participate in study abroad programs. As a women’s school graduate, I believe in the power of female education in women’s school while there are sceptical views of its existence.
Picture of Sachiko Kawai
My research on how medieval Japanese royal women strategized to overcome disparity is relevant in a time when COVID-19 has exposed ongoing problems tied to the vulnerability of (Japanese) women and gender stereotypes (e.g. recent remarks by Tokyo Olympics chief Mori).
Tohoku University
I am engaged in the development of a new device for embryo evaluation which measures embryo oxygen consumption and a new medication for infertility. Recently, I focused on causative genes of disorders of sex development and searched pathogenic variants using a whole-genome reference panel constructed by Tohoku Medical Megabank Organization.
Tohoku University
Image of Professor Hirano-Iwata
I am a leading expert in the reconstruction of an artificial cell membrane as a novel system for screening side effects of drugs on the heart. This system can assess the potential risks of drugs that unintentionally interfere with the function of membrane proteins in the heart muscle.
Masako Tanaka is a practitioner, activist and academic focusing on gender and migration issues in Japan. She is a professor at the Department of Global Studies at Sophia University, Japan.
Kyoto University
Mitsuyo Wada-Marciano is a professor at the Graduate School of Letters, Kyoto University, Japan. She is specialized in Japanese and East Asian cinemas with focus on digital media, disaster film, eco-cinema, and post-colonial cinema in cases of Japan, Taiwan, and Korea.
Hokkaido University
Madoka Ono is an associate professor at the Research Institute for Electronic Science/Green Nanotechnology Research Center at Hokkaido University and is the principal researcher at AGC Inc. Materials Integration Laboratories.
Tohoku University
Director of the International Research Institute of Disaster Science (IRIDeS) at Tohoku University since April 2014, and also is a professor of Tsunami Engineering
Hokkaido University
Professor, Faculty of Environmental Science, Hokkaido University
National Institute for Materials Science (NIMS)
Materials scientist studying structure and microstructure of metal and alloys by transmission electron microscopy. Specialize in light metals and quasicrystals.
Kyoto University
Masanori Shimono is an associate professor at Kyoto University Graduate School of Medicine.

Giants in history

Ruby Sakae Hirose (1904 – 1960) was a Japanese-American scientist whose research contributed significantly to our understanding of blood clotting, allergies and cancer.
Haisako Koyama (1916 – 1997) was a Japanese solar observer whose dedication to recording sunspots – cooler parts of the sun’s surface that appear dark – produced a sunspot record of historic importance.
Michiaki Takahashi (17 February 1928 – 16 December 2013) was a Japanese virologist who developed the first chickenpox vaccine.
Toshiko Yuasa (11 December 1909 – 1 February 1980) was the first Japanese female physicist whose research on radioactivity shed light on beta decay – the process in which an atom emits a beta particle (electron) and turns into a different element.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
In 1915, pathologist Katsusaburo Yamagiwa and his research assistant Koichi Ichikawa became the first to prove that chronic exposure to chemicals can cause cancer.
In 1915, Koichi Ichikawa along with pathologist Katsusaburo Yamagiwa became the first to prove that chronic exposure to chemicals can cause cancer.
Reiji Okazaki (8 October 1930 – 1 August 1975) and Tsuneko (7 June 1933) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.
Tsuneko (7 June 1933) and Reiji Okazaki (8 October 1930 – 1 August 1975) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
Hideki Yukawa (23 January 1907 – 8 September 1981) was awarded the Nobel Prize in Physics in 1949 for predicting the existence of the pi meson subatomic particle. Japan’s first Nobel laureate, Yakawa also expressed his support for nuclear disarmament by signing the Russell–Einstein Manifesto in 1955.
Shinichiro Tomonaga (31 March 1906 – 8 July 1979), together with Richard Feynman and Julian Schwinger, was awarded the Nobel Prize in Physics in 1965, for their contributions to advance the field of quantum electrodynamics. Tomonaga was also a strong proponent of peace, who actively campaigned against the proliferation of nuclear weapons and promoted the peaceful use of nuclear energy.
Japanese chemist Kenichi Fukui (4 October 1918 – 9 January 1998) was the first Asian scientist to be awarded the Nobel Prize in Chemistry. Together with Roald Hoffman, he received this honour in 1981 for his independent research into the mechanisms of chemical reactions.
Minoru Shirota (April 23, 1899 – March 10, 1982) was a Japanese microbiologist who invented the popular fermented drink Yakult.
Japanese physicist Ukichiro Nakaya (1900-1962) made the world’s first artificial snowflakes. He started his research on snow crystals in the early 1930s at Hokkaido University, where there is an unlimited supply of natural snow in winter. By taking over 3,000 photographs, he established a classification of natural snow crystals and described their relationship with weather conditions.
The techniques that make industrial pearl culturing possible were developed over a century ago at the Misaki Marine Biological Station in Japan. The station’s first director, Professor Kakichi Mitsukuri, emphasized to Kokichi Mikimoto in 1890 that stimulating pearl sac formation was important for pearl growth, and they went on to successfully develop methods for culturing pearls.
The field of solid-state ionics originated in Europe, but Takehiko Takahashi of Nagoya University in Japan was the first to coin the term ‘solid ionics’ in 1967. ‘Solid-state ionics’ first appeared in 1971 in another of his papers, and was likely a play on ‘solid-state electronics’, another rapidly growing field at the time.
Chika Kuroda (24 March 1884 – 8 November 1968) was a Japanese chemist whose research focussed on the structures of natural pigments.
Motoo Kimura (13 November 1924 – 13 November 1994) was a Japanese theoretical population geneticist who is best remembered for developing the neutral theory of molecular evolution.
Osamu Shimomura (27 August 1928 – 19 October 2018) was a Japanese organic chemist and marine biologist who dedicated his career to understanding how organisms emitted light.
Kikunae Ikeda (8 October 1864 – 3 May 1936) was a Japanese chemist who discovered the fifth basic taste, umami.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Kono Yasui (16 February 1880 – 24 March 1971) was a Japanese botanist who researched the genetics of poppies, corn and spiderworts and surveyed the plants that had been affected by the nuclear fallout after the atomic bombings of Hiroshima and Nagasaki.
Hitoshi Kihara (1893 – 1986) was one of the most famous Japanese geneticists of the 20th century. One of his most significant contributions was identifying sex chromosomes (X and Y) in flowering plants.
Michiyo Tsujimura (17 September 1888 – 1 June 1969) was a Japanese agricultural scientist and biochemist recognized for her research of green tea components.
A Japanese surgeon, Tetsuzo Akutsu (20 August 1922 – 9 August 2007) built the first artificial heart capable of keeping an animal alive.
Ogino Ginko (3 March 1851 – 23 June 1913) was the first registered female doctor to practise modern medicine in Japan.
Japanese geochemist Katsuko Saruhashi developed the first method and tools for measuring carbon dioxide in seawater