A schematic of the beam diameter measurement using transmitted X-rays old and new methods
07 Feb 2023
A research group at Osaka Metropolitan University has derived a new evaluation method for the measuring the size X-ray microbeams (diameter) through mathematical analysis. The group then verified the validity of the mathematically derived evaluation method by measuring the diameter of X-ray microbeams using metal wires of various diameters with an X-ray fluorescence analysis system for small areas and found that it was possible to calculate the beam diameter more accurately than the previous conventional evaluation method.
Depiction of blue light irradiation and two ‘catalyst gears’ cooperating to enable a reaction. (Credit: Tsuyoshi Mita)
07 Feb 2023
Two catalysts working in tandem enable inexpensive formate salts to perform difficult dearomative reactions, giving products potentially useful for drug development.
06 Feb 2023
Researchers led by Osaka University used cryogenic electron microscopy to analyze the atomic structure of the centromeric region of the chromosome, essential for cell division. A protein called CENP-A marks the centromere; the researchers showed that during interphase, CENP-A is bound by a protein called KNL2 to maintain the location of the centromere. During mitosis, KNL2 is replaced by CENP-C, allowing correct formation of the kinetochore complex for cell division.
06 Feb 2023
Researchers from Osaka University expanded the synthetic toolkit for preparing valuable chemical precursors from renewable feedstocks. They used microwave irradiation to dramatically improve the selectivity of the formose reaction, forming a simple six- and seven-carbon mixture that can be readily purified. These findings will help the chemicals industry minimize the use of fossil resources and improve the sustainability of manufacturing processes.
JWST pinpoints the ‘invisible’ engine that powers the galaxies in the middle of a collision
03 Feb 2023
Researchers used the James Webb Space Telescope to identify the precise location of a powerful energy source hidden by cosmic dust in the luminous merging galaxy IIZw096.
 Close up of the semi-automated synthesis robot used to generate training data (Photo: ICReDD).
03 Feb 2023
Researchers used a chemical synthesis robot and computationally cost effective A.I. model to successfully predict and validate highly selective catalysts.
02 Feb 2023
Researchers from Osaka University have used single carbon atom doping to form four chemical bonds in one step. Gamma-lactams (cyclic molecules that are common in antibiotics) were easily synthetically accessible from alpha, beta-unsaturated amides (an important molecule in cancer progression). The team chemically modified an anti-seizure medication in 96% yield, highlighting the work's utility to otherwise synthetically complex aspects of pharmaceutical development. The results of this work could become foundational to drug discovery and development.
The fluorescent blinking of cyanine dye (Alexa Fluor 647, pink star) bound to RNA changes depending on the structure of the RNA. When the RNA is folded like a hairpin, the fluorescent blinking is fast, and when the RNA switches to a G-quadruplex, the blinking is slow (Akira Kitamura).
02 Feb 2023
A new microscopic technique allows for the real-time study of RNA G-quadruplexes in living cells, with implications for the fight against amyotrophic lateral sclerosis.
01 Feb 2023
Osaka University researchers investigated the physics of laser-driven neutron sources, and found the relationship between the power and the neutrons generated. They were able to decrease the exposure time needed for neutron absorption experiments, which may be employed in biomedical research.
A process of continual learning for a synthetic multi-label dataset
31 Jan 2023
A research group at the Osaka Metropolitan University Graduate School of Informatics has developed a new learning method for artificial intelligence that combines classification performance for data with multiple labels with the ability to learn continually from data. Numerical experiments on real-world multi-label data indicate that the new method outperforms conventional approaches. The simplicity of this algorithm makes it easy to integrate it with other algorithms to devise new ones.
Drilling the ice core
31 Jan 2023
Data stored in ice cores dating back 55 years bring new insight into atmospheric levels of a molecule that can significantly affect weather and climate.
31 Jan 2023
Researchers from Osaka University have shown that a system known as the GET pathway is essential for efficient mitophagy, the process by which mitochondria are removed from cells. The GET pathway targets a protein assembly called the Ppg1–Far complex, which inhibits mitophagy, to the membrane of a part of the cell called the endoplasmic reticulum. When the GET pathway is defective, this complex instead becomes targeted to mitochondria, where it acts to suppress mitophagy.
30 Jan 2023
Researchers from Osaka University compared the sensitivity of rapid antigen tests (RATs) and polymerase chain reaction (PCR) tests for the Omicron variant of COVID-19 using data produced by the Japan Professional Football League. They found the comparative sensitivity of RATs for Omicron was not affected by the duration from the onset of symptoms to testing.
The back-projection analysis of seismic P-waves revealed correlations with eruptions observed by satellite (Kotaro Tarumi, Kazunori Yoshizawa. Earth and Planetary Science Letters. January 15, 2023)
27 Jan 2023
A “back-projection” technique reveals new details of the volcanic eruption in Tonga that literally shook the world.
27 Jan 2023
New research found that periodontitis, a common gum infection known to worsen other systemic diseases, could also be linked to atrial fibrosis — potentially clarifying its previously unknown connection with atrial fibrillation.
25 Jan 2023
Researchers from Osaka University have identified a protein, FER1L5, that is essential for sperm to acquire fertilizing ability. Sperm from mice lacking this protein were unable to undergo the “acrosome reaction”, which releases molecules that facilitate fertilization, resulting in impaired male fertility. As FER1L5 is also present in human sperm, this work may lead to new diagnostic methods and treatments for male infertility in humans.
24 Jan 2023
Osaka Metropolitan University scientists have succeeded in synthesizing fumaric acid, a raw material for plastics, from CO2 powered by solar energy—for the first time. Typically, fumaric acid is synthesized from petroleum as a raw material to make polybutylene succinate, a biodegradable plastic, but this research shows that it can be synthesized from CO2 and biomass-derived compounds using renewable energy.
24 Jan 2023
Researchers from Osaka University created a bound state of a proton and a K- meson known as Λ(1405), and measured its mass. The data implied that it consisted of five quarks. This work may help scientists develop a theory of exotic matter that existed in the early Universe or in neutron stars.
Schematic illustration of the spin transport demonstration of αNPD molecular thin film
24 Jan 2023
A research group, at the Osaka Metropolitan University Graduate School of Engineering, has succeeded in measuring spin transport in a thin film of αNPD molecules—a material well-known in organic light emitting diodes—at room temperature. They found that this thin molecular film has a spin diffusion length of approximately 62 nm, a length that could have practical applications in developing spintronics technology. In addition, while electricity has been used to control spin transport in the past, the thin molecular film used in this study is photoconductive, allowing spin transport control using visible light.
23 Jan 2023
New research from Osaka University indicates that more screen time at age 2 is associated with poorer communication and daily living skills at age 4—but when kids also play outdoors, some of the negative effects of screen time are reduced. Increasing outdoor play time could reduce the negative effects of screen time on daily living skills by almost 20%.
The new squid/synthetic polymer double-network gel
20 Jan 2023
The natural abilities of squid tissues and the creativity of chemists combine to take hydrogel research in new directions.
Visualization of coronavirus causing Covid19
19 Jan 2023
Researchers at Kanazawa University report in Nano Letters how high-speed atomic force microscopy can be used to assess the effectivity of spike-neutralizing antibodies for preventing COVID-19. The use of such antibodies offers a promising alternative to vaccines.
17 Jan 2023
In a study recently published in Cancer Science researchers from Kanazawa University show how some intestinal cancer cells lose their ability to spread as they divide and can be eliminated as the cancer grows.
The rocket carrying the experiment module being launched to carry out microgravity experiments (Photo: Swedish Space Corporation).
13 Jan 2023
Understanding how dust grains form in interstellar gas could offer significant insights to astronomers and help materials scientists develop useful nanoparticles.
13 Jan 2023
Researchers led by Osaka University demonstrated the role of endothelial cell-specific protein Roundabout4 (Robo4) in the reduction of vascular permeability and mortality in mouse models of severe infection. The research team identified a drug inhibitor that increased Robo4 expression and reduced mortality in sepsis and SARS-CoV-2 mouse models of infection. These findings may aid in the development of drugs to reduce the mortality rate of severe infectious diseases.
Sleeveless shirt-type wearable device and smartphone application track IBS patients’ sympathetic nervous system activity
12 Jan 2023
An Osaka Metropolitan University research group recorded the autonomic nervous system activity in patients with irritable bowel syndrome (IBS) and healthy subjects using a wearable device and a proprietary smartphone application to record daily life events such as defecation and sleep. As a result, they found that sympathetic nervous system activity was activated in IBS patients from 2 minutes before defecation and continued until 9 minutes after defecation. Further research is expected to improve the quality of life of IBS patients and elucidate the pathophysiology.
Red perilla cultivar Hoko-3
11 Jan 2023
A team of Japanese researchers created a high-quality genome assembly of red perilla, a step toward harnessing the plant’s potentially useful bioactive chemicals — and its medicinal properties.
Measuring knee extension velocity without external load
11 Jan 2023
Osaka Metropolitan University scientists delved into the relationship between gait function and knee extension velocity after total knee arthroplasty and compared the effects of various factors on walking. The results reveal that knee extension velocity, measured while seated, on the operated side was the most important determinant of gait function. These findings are expected to contribute to the development of new rehabilitation programs for efficient gait function improvement.
Aspergillus aculeatus
10 Jan 2023
An Osaka Metropolitan University research team analyzed the regulatory mechanisms of carbohydrate-hydrolyzing enzyme production in Aspergillus aculeatus, a filamentous fungus that produces enzymes with an excellent ability to degrade plant biomass. The team found that UDP-glucose 4-epimerase (Uge5), an enzyme known for its involvement in galactose metabolism, also regulates the expression of degrading enzyme genes in A. aculeatus. This is the very first report of Uge5’s roles in selective gene expression in response to different types of inducing sugars in filamentous fungi.
X-ray fluorescence spectra analyzed using Bayesian estimation
06 Jan 2023
A research group at Osaka Metropolitan University has succeeded in significantly reducing the measurement time of a glass standard sample by applying Bayesian estimation to X-ray fluorescence analysis. The ability to perform rapid non-contact elemental analysis in a nondestructive manner could lead to the widespread use of this technique in many fields, including the analysis of moving industrial products and waste materials while being carried on conveyor belts.


20 Mar 2012
The 25th International Conference on Microelectronic Test Structures brings together designers and users of test structures to discuss recent developments and future directions. It will be held at the Catamaran Hotel in San Diego, California, USA, on 20th March, 2012. The deadline for abstracts submission is 16th September 2011
17 Oct 2011
The goal of this conference is to create a forum for researchers, academicians, engineers and industry players from various fields of photonics with different experiences and backgrounds. It will take place at Le Meridien Hotel, Malaysia, from 17th to 19th October 2011
08 Nov 2011
The 15th International Conference on Thin Films (ICTF-15)focus on thin films and coatings. It will be held at Kyoto TERRSA in Kyoto, Japan on 8th to 11th November 2011
07 Dec 2011
The biennial International Semiconductor Device Research Symposium focuses on exploratory research in electronic and photonic materials and devices. It will be held at the University of Maryland, USA on 7th December to the 10th December. The deadline to submit abstracts will be 29th August, 2011
14 Oct 2012
The International Workshop on Nitride Semiconductors (IWN2012) focuses on issues related to nitride materials and devices. It will be held in Sapporo, Japan on the 14th October 2012
28 Sep 2011
The 60th Symposium on Macromolecures is an annual event on the latest developments in polymer science. It also provides researcher and engineers in relevant fields a venue for discussions. It will takes place from 28th to 30th September.
21 Apr 2012
The Tenth Annual Workshop on Microelectronics and Electron Devices will provide a forum for all aspects of microelectronics. It will be held at the Boise State University, USA on 21st April 2012. The deadline for manuscript submission is 27th January, 2012.
29 Sep 2011
This conference aims to disseminate results on the NEDO project “Research and Development of Nanoparticle Characterization Methods - Evaluating Risks associated with Manufactured Nanomaterials”, and provide a forum for discussions on these results.
29 Nov 2011
The Nanomaterials Conference 2011 will be held in Xcaret, Mexico, on 29th November to 3rd December. The poster abstract deadline for this conference will be the 28th September
25 Oct 2011
The NT4D Conference is committed to providing a fertile and stimulating forum for discussion on recent nanotechnology innovations which maximize the impact to defense and dual-use technologies. It will take place at Hyatt Regency Bellevue, WA, USA, from 25th to 28th October.
24 May 2012
The 13th International Conference on Optimization of Electrical and Electronic Equipment (OPTIM) is an International conference on the latest technology of electricity and electronic system. It will be held in Brasov, Romania on 24th May 2012.
11 Sep 2011
The 6th International Conference on Fracture of Polymers, Composites and Adhesives invites papers on polymers, composites and adhesives.
28 Apr 2012
The Expo is the nation’s largest celebration of all things science & engineering since 2010. It will be held in Washington DC, USA on 28th April 2012
10 Jul 2012
The UGIM Symposium brings together educators and researchers on the field of micro/nanotechnology laboratory development and management. It will be held at the University of California, USA on 10th July 2012.
30 Nov 2011
The Asian BioCeramics Symposium is held annually to encourage interest in bioceramics and related fields. It will be held in Tsukuba, Japan on the 30th November to 2nd December.
05 Dec 2011
An exhibition for latest products, technology, services, peripheral devices and information that contribute to global environmental conservation
04 Oct 2011
CEATEC JAPAN is the Cutting-edge IT & Electronics Comprehensive Exhibition that attracts around 200,000 attendees.
17 Oct 2011
A unique environment for understanding, developing, and sharing reliability technology and test methodology for present and future semiconductor
06 Nov 2011
This symposium explores a variety of topics, include Microrobotics, Micromechatronics, Nanotechnology and more
28 Nov 2011
The PVSEC-21 will cover the entire field related with PVs from materials to systems as well as its deployment
03 Oct 2011
This conference aims to present new concepts, techniques and applications of atomically controlled processes at surfaces, interfaces and nanostructures.
07 Nov 2011
The ICAE 2011 is intended to provide an open forum to all participants with an opportunity to present the latest important findings in research activities in the field of electrical and electronic materials.
08 Sep 2011
The RIKEN Omics Science Center (OSC) in Yokohama, Japan, will hold a joint international training course entitled 'The Bioinformatics Roadshow' in collaboration with the European Bioinformatics Institute (EMBL-EBI) on 8–9 September 2011.
23 Sep 2012
The conference will be held on 23rd September 2012 to 28th September 2012 at Nara New Public Hall, Nara Japan
19 Feb 2012
The conference will be held on 19th February 2012 to 23rd February 2012 at San Francisco Marriott Marquis Hotel, San Francisco, CA, USA
28 Dec 2011
The conference will be held on 28th December to 30th December at Dubai, UAE
17 Nov 2011
The conference will be held on 17th November to 18th November at Tianjin, P.R. China
09 Nov 2011
The conference will be held on 7th November 2011 to 10th November 2011 at International Convention Center (ICC), Jeju, Korea
07 Nov 2011
The conference will be held on 7th November 2011 to 10th November 2011 at DoubleTree Hotel San Jose, San Jose, CA, USA


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Giants in history

Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
In 1915, pathologist Katsusaburo Yamagiwa and his research assistant Koichi Ichikawa became the first to prove that chronic exposure to chemicals can cause cancer.
In 1915, Koichi Ichikawa along with pathologist Katsusaburo Yamagiwa became the first to prove that chronic exposure to chemicals can cause cancer.
Reiji Okazaki (8 October 1930 – 1 August 1975) and Tsuneko (7 June 1933) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.
Tsuneko (7 June 1933) and Reiji Okazaki (8 October 1930 – 1 August 1975) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
Hideki Yukawa (23 January 1907 – 8 September 1981) was awarded the Nobel Prize in Physics in 1949 for predicting the existence of the pi meson subatomic particle. Japan’s first Nobel laureate, Yakawa also expressed his support for nuclear disarmament by signing the Russell–Einstein Manifesto in 1955.
Shinichiro Tomonaga (31 March 1906 – 8 July 1979), together with Richard Feynman and Julian Schwinger, was awarded the Nobel Prize in Physics in 1965, for their contributions to advance the field of quantum electrodynamics. Tomonaga was also a strong proponent of peace, who actively campaigned against the proliferation of nuclear weapons and promoted the peaceful use of nuclear energy.
Japanese chemist Kenichi Fukui (4 October 1918 – 9 January 1998) was the first Asian scientist to be awarded the Nobel Prize in Chemistry. Together with Roald Hoffman, he received this honour in 1981 for his independent research into the mechanisms of chemical reactions.
Minoru Shirota (April 23, 1899 – March 10, 1982) was a Japanese microbiologist who invented the popular fermented drink Yakult.
Japanese physicist Ukichiro Nakaya (1900-1962) made the world’s first artificial snowflakes. He started his research on snow crystals in the early 1930s at Hokkaido University, where there is an unlimited supply of natural snow in winter. By taking over 3,000 photographs, he established a classification of natural snow crystals and described their relationship with weather conditions.
The techniques that make industrial pearl culturing possible were developed over a century ago at the Misaki Marine Biological Station in Japan. The station’s first director, Professor Kakichi Mitsukuri, emphasized to Kokichi Mikimoto in 1890 that stimulating pearl sac formation was important for pearl growth, and they went on to successfully develop methods for culturing pearls.
The field of solid-state ionics originated in Europe, but Takehiko Takahashi of Nagoya University in Japan was the first to coin the term ‘solid ionics’ in 1967. ‘Solid-state ionics’ first appeared in 1971 in another of his papers, and was likely a play on ‘solid-state electronics’, another rapidly growing field at the time.
Chika Kuroda (24 March 1884 – 8 November 1968) was a Japanese chemist whose research focussed on the structures of natural pigments.
Motoo Kimura (13 November 1924 – 13 November 1994) was a Japanese theoretical population geneticist who is best remembered for developing the neutral theory of molecular evolution.
Osamu Shimomura (27 August 1928 – 19 October 2018) was a Japanese organic chemist and marine biologist who dedicated his career to understanding how organisms emitted light.
Kikunae Ikeda (8 October 1864 – 3 May 1936) was a Japanese chemist who discovered the fifth basic taste, umami.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Kono Yasui (16 February 1880 – 24 March 1971) was a Japanese botanist who researched the genetics of poppies, corn and spiderworts and surveyed the plants that had been affected by the nuclear fallout after the atomic bombings of Hiroshima and Nagasaki.
Hitoshi Kihara (1893 – 1986) was one of the most famous Japanese geneticists of the 20th century. One of his most significant contributions was identifying sex chromosomes (X and Y) in flowering plants.
Michiyo Tsujimura (17 September 1888 – 1 June 1969) was a Japanese agricultural scientist and biochemist recognized for her research of green tea components.
A Japanese surgeon, Tetsuzo Akutsu (20 August 1922 – 9 August 2007) built the first artificial heart capable of keeping an animal alive.
Ogino Ginko (3 March 1851 – 23 June 1913) was the first registered female doctor to practise modern medicine in Japan.
Japanese geochemist Katsuko Saruhashi developed the first method and tools for measuring carbon dioxide in seawater