Nature Communications

A team of researchers from Taiwan has developed PanMETAI, an AI-powered platform that analyses metabolic fingerprints in a simple blood sample to detect pancreatic cancer at its earliest stages—when treatment is most effective—achieving up to 94% diagnostic accuracy.

Testing air and surfaces can detect dangerous viruses earlier and more comprehensively than testing birds alone

Diastereomers are molecules with identical structures that are not mirror images of each other, described as anti or syn for molecules without rings. Researchers at The University of Osaka developed a strategy for using a rigid cage-like molecule to produce an anti-diastereomer in high yield. This diastereomer can only be obtained as a minor byproduct by traditional methods. The strategy is expected to become a key technology for making medicines and other bioactive substances.

A team led by researchers at Tohoku University have taken the first step toward developing antiferromagnetic technology. They detected a liquid-crystal phase that may change the game for spintronic devices.

Researchers from The University of Osaka have developed a mouse model for achondroplasia. The model identified the importance of a signaling molecule called FGFR3 and a pathway called CREB in regulating bone growth. This pathway is also at least partially responsible for the pathology associated with achondroplasia and impaired bone growth. Their findings advance our understanding of the process of bone growth and provide novel therapeutic targets for achondroplasia.

Researchers at The University of Osaka have developed a method to reproducibly form subnanometer pores within a solid-state nanopore. A voltage-driven chemical reaction produces a precipitate that fills and closes the nanopore, while dissolution reopens conductive pathways. This process forms many subnanometer-sized pores, whose effective size can be tuned by changing reactant composition and pH. These ultrasmall pores mimic biological ion channels and enable studies of ion transport in confined spaces.

- DGIST Professor Youngwook Kim’s research team uncovers a new principle for “ultralow-power memory” without artificial deformation - Presents a novel physical principle for the realization of next-generation low-power electronic devices and quantum memory

An international team from Kanazawa University (Japan), Tohoku University (Japan), LPP (France), and partners has demonstrated that chorus emissions, natural electromagnetic waves long studied in Earth’s magnetosphere, also occur in Mercury’s magnetosphere exhibiting similar chirping frequency changes. Using the Plasma Wave Investigation instrument aboard BepiColombo’s Mercury orbiter Mio, six Mercury flybys between 2021 and 2025 detected plasma waves in the audible range. Comparison with decades of GEOTAIL data confirmed identical instantaneous frequency changes. This provides the first reliable evidence of intense electron activity at Mercury, advancing understanding of auroral processes across the solar system.

Japanese researchers have developed a living sensor display that turns engineered skin into a biological monitor, visually indicating internal inflammation without requiring blood sampling.

Scientists at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have captured real-time images showing how a key brain enzyme organizes itself to help memory formation. Their study, published in Nature Communications, reveals that the enzyme CaMKII forms mixed α/β subunit structures whose interactions stabilize learning-related signals in neurons.

National Taiwan University study reveals how intracellular bacteria co-opt mitochondrial transporters to evade immune defenses, suggesting that blocking this pathway could sensitize drug-resistant pathogens to host immunity.

The seismic ultralow velocity zones critically affect the regional thermochemical structures at both sides of the core-mantle boundary, and possibly the geomagnetic evolution of our planet.

Researchers at National Taiwan University have uncovered, for the first time at atomic resolution, how the human proteasome recognizes branched ubiquitin chains. This breakthrough reveals a multivalent decoding mechanism that enhances protein degradation accuracy and speed.

Rechargeable batteries get a supercharged boost from newly developed RAMOFs that don’t break down in water, which was previously a major problem for this material.

The origin of the elusive preference of copper chalcogenides for selectively converting carbon dioxide (CO2) into formate has long puzzled researchers. Researchers at National Taiwan University have identified a charge-redistribution mechanism that resolves this long-standing debate, providing fundamental insight into the basis of their exceptional selectivity.

Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have developed a breakthrough method for quantitative imaging of ATP levels inside living cells. The study, published in Nature Communications, introduces qMaLioffG, a genetically encoded fluorescence lifetime indicator that allows scientists to observe how cells produce and consume energy in real time.

Slow earthquakes have been discovered to exhibit anomalously slow, long-lasting, and small slips, adjacent to regular earthquakes where we sometimes feel catastrophic vibration. However, no one knows the reason why they show such strange characteristics. In a study published in a scientific journal Nature Communications, researchers at The University of Osaka succeeded in experimentally reproducing the multiple features of slow earthquakes in the lab and suggested the grain-scale origin of them based on their direct observations.

Scientists turn essential oil compounds into durable yet decomposable polymers.

Superconductive materials can conduct electricity with no resistance, but typically only at very low temperatures. Realizing superconductivity at room temperature could enable advanced, energy-efficient electronics and other technologies. Now, an international research team is one step closer to such an achievement.

Researchers from National Taiwan University Hospital and collaborating institutions have demonstrated that finerenone, a new-generation nonsteroidal mineralocorticoid receptor antagonist (MRA), significantly reduces the risk of death and major heart and kidney events compared with spironolactone in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D).

Scientists at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have discovered how a gene-regulating protein forms tiny liquid-like droplets inside the cell nucleus (the compartment that stores and manages DNA) to guard against cancer. Their study, published in Nature Communications, shows that these protein droplets act as control centers that keep tumor-suppressor genes switched on.

Lactate, once thought to be just a waste product, is now recognized as an important fuel and signaling molecule in the brain. This study introduces a red fluorescent biosensor that allows scientists to visualize both brain metabolism and neuronal activity at the same time.

- Wafer-Scale Integration of Next-Generation Memristor Semiconductors: Establishing a World-Class Platform for High-Density, Low-Power Computing - Research Findings Published in Nature Communications

The balance of nutrition in early childhood affects height.

Researchers at Tohoku University found that a certain catalyst tends towards different reaction mechanisms at high versus low temperatures. This finding can be used to tailor catalysts with more stability, which ultimately could lead to upgrades for electrochemical devices such as batteries.

More than 40% of existing and planned offshore wind farm sites in Europe and Asia are exposed to wind speeds above the maximum capacity of some turbines, highlighting the need for these energy infrastructures to adapt to extreme wind events associated with climate change.

A team of international researchers has developed alternatives to antibiotics that prevent infection of cow udders, called bovine mastitis, to address rising antibiotic resistance and concerns around milk contamination from antibiotic residues.

Researchers have developed a method to produce strong, biodegradable plastic from bamboo.

Researchers from The University of Osaka, AIST, Okayama University, and the University of Tokyo applied an innovative computational-analysis technique to clarify the atomic structure of soft, easily deformable regions in amorphous silicon. They discovered that these regions combine medium-range order with local disorder, a finding that will guide the design of more durable amorphous materials.

The risk of extreme water shortages due to climate change is predicted to affect almost 74% of drought-prone regions by 2100, according to new research in Nature Communications. In the first known published estimation of its kind, the authors report that hotspots of water scarcity will likely emerge across the Mediterranean, southern Africa, and parts of North America by the 2020s and 2030s.