Nature Communications

Scientists at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have captured real-time images showing how a key brain enzyme organizes itself to help memory formation. Their study, published in Nature Communications, reveals that the enzyme CaMKII forms mixed α/β subunit structures whose interactions stabilize learning-related signals in neurons.

National Taiwan University study reveals how intracellular bacteria co-opt mitochondrial transporters to evade immune defenses, suggesting that blocking this pathway could sensitize drug-resistant pathogens to host immunity.

The seismic ultralow velocity zones critically affect the regional thermochemical structures at both sides of the core-mantle boundary, and possibly the geomagnetic evolution of our planet.

Researchers at National Taiwan University have uncovered, for the first time at atomic resolution, how the human proteasome recognizes branched ubiquitin chains. This breakthrough reveals a multivalent decoding mechanism that enhances protein degradation accuracy and speed.

Rechargeable batteries get a supercharged boost from newly developed RAMOFs that don’t break down in water, which was previously a major problem for this material.

The origin of the elusive preference of copper chalcogenides for selectively converting carbon dioxide (CO2) into formate has long puzzled researchers. Researchers at National Taiwan University have identified a charge-redistribution mechanism that resolves this long-standing debate, providing fundamental insight into the basis of their exceptional selectivity.

Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have developed a breakthrough method for quantitative imaging of ATP levels inside living cells. The study, published in Nature Communications, introduces qMaLioffG, a genetically encoded fluorescence lifetime indicator that allows scientists to observe how cells produce and consume energy in real time.

Slow earthquakes have been discovered to exhibit anomalously slow, long-lasting, and small slips, adjacent to regular earthquakes where we sometimes feel catastrophic vibration. However, no one knows the reason why they show such strange characteristics. In a study published in a scientific journal Nature Communications, researchers at The University of Osaka succeeded in experimentally reproducing the multiple features of slow earthquakes in the lab and suggested the grain-scale origin of them based on their direct observations.

Scientists turn essential oil compounds into durable yet decomposable polymers.

Superconductive materials can conduct electricity with no resistance, but typically only at very low temperatures. Realizing superconductivity at room temperature could enable advanced, energy-efficient electronics and other technologies. Now, an international research team is one step closer to such an achievement.

Researchers from National Taiwan University Hospital and collaborating institutions have demonstrated that finerenone, a new-generation nonsteroidal mineralocorticoid receptor antagonist (MRA), significantly reduces the risk of death and major heart and kidney events compared with spironolactone in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D).

Scientists at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have discovered how a gene-regulating protein forms tiny liquid-like droplets inside the cell nucleus (the compartment that stores and manages DNA) to guard against cancer. Their study, published in Nature Communications, shows that these protein droplets act as control centers that keep tumor-suppressor genes switched on.

Lactate, once thought to be just a waste product, is now recognized as an important fuel and signaling molecule in the brain. This study introduces a red fluorescent biosensor that allows scientists to visualize both brain metabolism and neuronal activity at the same time.

- Wafer-Scale Integration of Next-Generation Memristor Semiconductors: Establishing a World-Class Platform for High-Density, Low-Power Computing - Research Findings Published in Nature Communications

The balance of nutrition in early childhood affects height.

Researchers at Tohoku University found that a certain catalyst tends towards different reaction mechanisms at high versus low temperatures. This finding can be used to tailor catalysts with more stability, which ultimately could lead to upgrades for electrochemical devices such as batteries.

More than 40% of existing and planned offshore wind farm sites in Europe and Asia are exposed to wind speeds above the maximum capacity of some turbines, highlighting the need for these energy infrastructures to adapt to extreme wind events associated with climate change.

A team of international researchers has developed alternatives to antibiotics that prevent infection of cow udders, called bovine mastitis, to address rising antibiotic resistance and concerns around milk contamination from antibiotic residues.

Researchers have developed a method to produce strong, biodegradable plastic from bamboo.

Researchers from The University of Osaka, AIST, Okayama University, and the University of Tokyo applied an innovative computational-analysis technique to clarify the atomic structure of soft, easily deformable regions in amorphous silicon. They discovered that these regions combine medium-range order with local disorder, a finding that will guide the design of more durable amorphous materials.

The risk of extreme water shortages due to climate change is predicted to affect almost 74% of drought-prone regions by 2100, according to new research in Nature Communications. In the first known published estimation of its kind, the authors report that hotspots of water scarcity will likely emerge across the Mediterranean, southern Africa, and parts of North America by the 2020s and 2030s.

Researchers from The University of Osaka found that the radial spoke protein CFAP91 is crucial for flagellum formation in sperm, and that the proximal protein EFCAB5 is important for sperm motility. Loss of function of either of these proteins impairs spermatogenesis, suggesting that their mutation or loss can lead to male infertility.

To reduce plastic pollution and promote environmental sustainability, scholars from the Lingnan University School of Interdisciplinary Studies and their research team have developed a successful new eco-friendly bioplastic material. Unlike conventional plastics, it degrades naturally into harmless water and carbon dioxide in as little as 29 days under ambient conditions, and is a practical way to mitigate global plastic pollution. Their study, “Sustainable DNA-polysaccharide hydrogels as recyclable bioplastics”, was recently published in the respected journal Nature Communications.

Researchers from The University of Osaka have found that they can keep mouse uterine tissue alive outside of the body, allowing them to directly observe embryonic implantation and development. Their technique brings hope for patients with infertility, and may allow for the development of therapies to treat recurrent implantation failure and improve the chance of implantation success using assisted reproductive technologies.

Researchers from The University of Osaka found that macrophages use microautophagy, mediated by Rab32-positive lysosome-related organelles, to directly engulf damaged mitochondria and other organelles. This was discovered to be independent of macroautophagy. Key factors in this process include Rab32 GTPase, PI(3,5)P2, ubiquitination, and p62/SQSTM1. By clearing mitochondria, microautophagy promotes metabolic reprogramming toward glycolysis, supporting M1 macrophage polarization. Loss of Rab32/38 disrupts this process, highlighting microautophagy’s role in regulating macrophage function.

Researchers from The University of Osaka used electricity to drive a reaction to form a novel hetero[8]circulene consisting of five hexagons and three pentagons (called a dioxaza[8]circulene). The dioxaza[8]circulene is unsymmetrical, unlike existing hetero[8]circulenes. The novel molecule can be produced from commercially available materials by a two-step method that simultaneously forms six new bonds with only water as a byproduct. The dioxaza[8]circulene may have potential as a photocatalyst, and be used to speed up reactions triggered by light.

Paving the way for cleaner air and greener chemical processes.

Researchers from South Korea engineered a robotic folding sheet that can crawl across a surface as well as grasp and lift various objects.

YNU researchers develop a novel method to predict alloy microstructures with unprecedented speed and accuracy.

In the 2D ferromagnet Fe5GeTe2, researchers reveal atomic-scale coherence linking charge density waves, Kondo physics, and ferromagnetism—the first direct observation of synchronized electric and magnetic quantum states.