15 Apr 2021
Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the major treatment option, but the clinical result is unsatisfactory. A research team led by biologists at City University of Hong Kong (CityU) has identified and characterised a set of specific super-enhancers that stimulate the activity of the related critical cancer genes. The research has also discovered that the deletion of certain specific super-enhancers could reduce tumour cell growth. The latest findings may help discover new effective drug targets for TNBC patients to improve their survival chance.
19 Mar 2021
Through a series of prosocial choice tasks, researchers reveal prosocial and antisocial characteristics in male convict cichlid fish. The fish distinguish between female breeding partners, unknown females, and rival males by adjusting their actions to either provide food for both them and the females or avoid providing food for the rival males.
10 Mar 2021
Energy-efficient light-emitting diodes (LEDs) have been used in our everyday life for many decades. But the quest for better LEDs, offering both lower costs and brighter colours, has recently drawn scientists to a material called perovskite. A recent joint-research project co-led by the scientist from City University of Hong Kong (CityU) has now developed a 2D perovskite material for the most efficient LEDs.
25 Feb 2021
Researchers from Tohoku University have developed a biobattery-powered device capable of both delivering large molecule pharmaceuticals across the skin barrier and extracting interstitial fluid for diagnostic purposes.
12 Feb 2021
In a study published in Nature Communications, cancer researchers at Kanazawa University identify mechanisms by which malignant tumor cells extend their toxicity to distinct cell types and in turn help them spread.
10 Feb 2021
Researchers at The University of Tokyo discover a new law about how the complex network of phase-separated structures grows with time, which may lead to more efficient batteries and industrial catalysts
29 Jan 2021
Although genome sequencing has come leaps and bounds over the past 20 years, there did not exist a reference genome specific to the Japanese. That is until now. Researchers at Tohoku University have completed and released the first Japanese reference genome by analyzing the genomes of three Japanese individuals using high coverage, long-read next-generation sequencing technologies.
20 Jan 2021
Hokkaido University scientists have found a way to prevent gold nanoparticles from clumping, which could help towards their use as an anti-cancer therapy.
12 Jan 2021
An atomic switch is bringing us closer to highly effective solid-state batteries for electric vehicles.
24 Dec 2020
Tohoku University scientists have, for the first time, provided experimental evidence that cell stickiness helps them stay sorted within correct compartments during development. How tightly cells clump together, known as cell adhesion, appears to be enabled by a protein better known for its role in the immune system. The findings were detailed in the journal Nature Communications.
23 Dec 2020
A joint research team co-led by City University of Hong Kong (CityU) has developed a novel computational tool that can reconstruct and visualise three-dimensional (3D) shapes and temporal changes of cells, speeding up the analysing process from hundreds of hours by hand to a few hours by computer. Revolutionising the way biologists analyse image data, this tool can advance further studies in developmental and cell biology, such as the growth of cancer cells.
07 Dec 2020
Scientists from Japan and the USA have confirmed the presence in meteorites of a key organic molecule which may have been used to build other organic molecules, including some used by life. The discovery validates theories of the formation of organic compounds in extraterrestrial environments.
02 Dec 2020
“Superbug” resistant to strong antibiotics is a ticking time bomb in global public health. A joint study led by a scientist from City University of Hong Kong (CityU) has traced the potential origin of an antibiotic resistance gene and identified a type of bacteria as the possible source. The team also studied the gene’s transmission mechanisms and published their findings recently, in the hope of blocking its transmission.
23 Nov 2020
A chance discovery leads to a simple process that can introduce ‘oxygen-missing layers’ into perovskite oxynitrides, changing their properties.
20 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has recently reported a significant discovery that could bring solar hydrogen production a step closer to reality.
20 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has developed a ‘carbon-based high-efficiency electrochemical catalyst’ for use to produce H2O2.
20 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has designed and synthesized a vertical two-dimensional (2D) layered structure to develop materials that exhibit excellent performance in terms of gas storage and for the removal of toxic substances.
19 Nov 2020
Scientists have found a way to control an interaction between quantum dots that could lead to more efficient solar cells.
19 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has succeeded in fabricating highly integrated arrays of PTFTs and logic gates via all-solution processing.
19 Nov 2020
12 Nov 2020
The quest for high throughput intelligent computing paradigms - for big data and artificial intelligence - and the ever-increasing volume of digital information has led to an intensified demand for high-speed and low-power consuming next-generation electronic devices. The "forgotten" world of antiferromagnets (AFM), a class of magnetic materials, offers promise in future electronic device development and complements present-day ferromagnet-based spintronic technologies (Fig. 1).
14 Oct 2020
Osaka City University unravels the atomic architecture of the “Nap” protein complex found on Mycoplasma pneumoniae.
06 Oct 2020
Researchers at Kanazawa University report in Nature Communications the mechanism making some lung-cancer patients resistant to the drug osimertinib. In addition, they suggest a combined drug treatment resolving osimertinib resistance in the case of cancer cells expressing low amounts of AXL, a protein belonging to the class of receptor tyrosine kinases.
18 Sep 2020
Drugs tackling chronic myelogenous leukemia have completely transformed prognoses of patients over the last couple of decades, with most cases going into remission. But drug resistance can occur, leading to relapses. Targeting the lipids involved in regulating part of a leukemia stem cell’s life span offers a potential second route to defeat the disease—and solid tumorous cancers as well.
15 Sep 2020
A team of scientists has unraveled the molecular mechanism behind one of the causes of colorectal cancer, and a treatment target.
09 Sep 2020
Running is a fundamental mode of human movement that most of us perform effortlessly without conscious thought. Some may run regularly for exercise, or even undergo serious, professional training for completing marathons. This apparent ease of running belies the enormous biomechanical complexity of running, the coordinated control of which is accomplished by an intricate neuronal network in the brain and spinal cord.
07 Sep 2020
Researchers at Kanazawa University report in Nature Communications the discovery that in the developing fly brain, neurons stemming from the same parent cell experience repulsion. This lineage-dependent repulsion is regulated by a protein known as Dscam1.
24 Aug 2020
Ice is melting at a surprisingly fast rate underneath Shirase Glacier Tongue in East Antarctica due to the continuing influx of warm seawater into the Lützow-Holm Bay.
17 Aug 2020
The human brain efficiently executes highly sophisticated tasks, such as image and speech recognition, with an exceptionally lower energy budget than today's computers can. The development of energy-efficient and tunable artificial neurons capable of emulating brain-inspired processes has, therefore, been a major research goal for decades.
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