Science

The ever-increasing workload of data centers calls for new ways to store and access data. Researchers from the Daegu Gyeongbuk Institute of Science and Technology, Korea, have developed a new approach to manage databases in solid state drives, providing marked performance improvements in read/write delays and offloading database computation tasks from CPUs to increase efficiency and reduce power consumption.

Researchers from Tohoku University’s Graduate School of Engineering have discovered a novel iron-based superelastic alloy capable of withstanding extreme temperatures—both high and low.

Nanoprodrugs have immense potential for cancer treatment, more so than conventional drug delivery systems. Researchers have, for the first time, developed a comprehensive study on the dynamics of the SN-38 nanoprodrug.

The human brain efficiently executes highly sophisticated tasks, such as image and speech recognition, with an exceptionally lower energy budget than today's computers can. The development of energy-efficient and tunable artificial neurons capable of emulating brain-inspired processes has, therefore, been a major research goal for decades.

Duke-NUS spinout, PairX, led by US and Singapore scientists and investors, to advance immunotherapy biotech exclusively licensed from Duke-NUS.

Researchers in Kanazawa University has recently reported their study in Nano Letters regarding a high-speed atomic force microscopy study on a biological event that happens during flu virus enters infects its host cell. The real-time visualization of influenza A hemagglutinin (HA) has enhanced the understanding of fusogenic transition of HA and its interactions with host endosomes.

In catalytic reactions with organocatalysts, it is difficult to control radical reactions. We designed a thiazolium-type N-heterocyclic carbene catalyst having an N-neopentyl group. This catalyst was found to actively control radical reactions and enabled production of more than 35 species of bulky dialkyl ketones from an aliphatic aldehyde and an aliphatic carboxylic acid derivative through a radical relay mechanism. This catalyst is expected to open the way for acceleration of drug discovery research.

A group of researchers have demonstrated that, from seven methods commonly used to test for viruses in untreated wastewater, an adsorption-extraction technique can most efficiently detect SARS-CoV-2. This gives us another tool to detect the presence and spread of the COVID-19 pandemic

A group of researchers from three Japanese universities has discovered why the western subarctic Pacific Ocean, which accounts for only 6 percent of the world’s oceans, produces an estimated 26 percent of the world’s marine resources.

Understanding the microscopic origin of different physical properties of solids is of fundamental importance for condensed-matter physics and for materials applications. Yet, there is still a lot of unknowns in amorphous materials due to their disordered atomic structure. Recently, with the state-of-the-art neutron scattering instrumentation and molecular dynamic simulations, an international research team, led by physicists from City University of Hong Kong (CityU), has demonstrated the existence of high-frequency transverse phonons in metallic glass for the first time. Their findings also suggest that the atomic structure correlates with its atomic dynamics, providing new insight for understanding the atomic structure-dynamics relationship in disordered materials.

Research at Kanazawa University as reported in Scientific Reports demonstrates atomic force microscopy imaging that gets around the challenges of exciting very small cantilevers at their high megahertz resonance frequencies. The approach accomadates wide frequency bandwiths, and is applicable for photosensitive materials in a wide range of liquids.

Researchers at Kanazawa University report in ACS Nano a high-speed atomic-force microscopy study of the formation of protein fibrils (amyloids) associated with pathologies in collaborated research with Showa University. Mixing different variants of a single protein and changing the acidity of its environment is shown to result in significant variations in amyloid structure and elongation rates.

In a recently published paper in Earth and Planetary Science Letters, researchers from the Geodynamics Research Center, Ehime University and the University of Lille combine numerical modeling of dislocation glide and results from diffusion experiments to revisit the rheology of wadsleyite, ringwoodite and majorite garnet under geological strain rates across the transition zone of the Earth’s mantle based on theoretical plasticity modeling.

The electron is an elementary particle, a building block on which other systems evolve. With specific properties such as spin, or angular momentum, that can be manipulated to carry information, electrons are primed to advance modern information technology. An international collaboration of researchers has now developed a way to extend and stabilize the lifetime of the electron's spin to more effectively carry information.

Hokkaido University researchers have found a soft and wet material that can memorize, retrieve, and forget information, much like the human brain. They report their findings in the journal Proceedings of the National Academy of Sciences (PNAS).

Epstein-Barr virus rewires host epigenome to turn on latent genetic enhancers that activate proto-oncogenes, leading to tumorigenesis in stomach cancer

Jointly organised by the Agency for Science, Technology and Research (A*STAR) and Science Centre Singapore

The International Network for Government Science Advice Asia is organising an essay contest on “How is science advice used for the government in your country?”. The deadline is 31st of August 2020.

A hemispherical vanadium oxide cluster has a cavity that can accommodate a bromine molecule. It was found that a bromine molecule trapped in the cavity was polarized and that an alkane molecule like pentane, butane and propane could be brominated with the bromine molecule in the cavity with a selectivity differing from ordinary bromination. The present findings are expected to be useful for polarization of small molecules and design of highly functional catalysts.

Researchers at Kanazawa University report in Biomaterials a high-speed atomic-force microscopy study of protein filaments in the nuclear pore complex. The visualization in real-time of the filaments’ dynamics is an important step in our understanding of molecular transport mechanisms between a cell nucleus and its surrounding medium.

Low oxygen levels in water (hypoxia) pose a significant threat to marine and freshwater ecosystems worldwide, as highlighted in the latest research findings of The Education University of Hong Kong (EdUHK) in an article titled “Low oxygen levels affect reproductive function in female fish – across multiple generations”, featured in Science for Environment Policy (Issue 536). This novel finding shows that hypoxia not only impairs reproduction in female fish (Oryzias melastigma), but the adverse effects can be passed on to their descendants in subsequent generations, posing a long-term threat to the sustainability of natural fish populations around the world.

A method that involves infecting liver cells with mosquito-bred parasites could improve the study of malaria in India.

The Annual Peace & Security Review 2020 is a comprehensive overview of Myanmar’s security landscape, with insider information and in-depth analysis to inform and nudge the country one step closer towards peace.

A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has unveiled a novel material that could enable major leaps in the miniaturization of electronic devices.

A research team led by Professor Jerome HUI Ho Lam from the School of Life Sciences at The Chinese University of Hong Kong (CUHK) has decoded for the first time the high-quality genomes of two jellyfish commonly found in Asian waters, including the edible flame jellyfish. Further studies have revealed many unexpected biological findings, including the identification of hormones which are thought to be only contained in arthropods like insects. The findings, just published in the top scientific journal Nature Communications, provide references for further studies on the evolution, ecological roles and population bloom of jellyfish.

Researchers at Kanazawa University report in the Biophysical Journal that the process of cell removal from an epithelial layer follows from an inherent mechanical instability. Moreover, the forces generated by an extruding cell can drive the extrusion of other cells in a particular direction.

Researchers at the University of Tsukuba and RIKEN in Japan spark a hibernation-like state in mice—a species that does not naturally hibernate

We move our eyes several times per second. These fast eye movements, called saccades, create large image shifts on the retina - making our visual system work hard to maintain a stable perceptual world. Remapping the retinal image compensates for this; however, errors in actual eye movements cause image shifts, even with remapping.

Researchers from University of Tsukuba and the University of Tokyo identify neurons responsible for memory consolidation during REM sleep

A highly accurate machine learning tool could help doctors tailor individualized treatments for people with glioma brain tumours.