Science

A research group led by Associate Professor Katsuya Sakai, Researcher Nichole Marcela Rojas-Chaverra, and Professor Kunio Matsumoto of the Cancer Research Institute and Nano-Life Science (WPI-NanoLSI) at Kanazawa University has developed a long-acting, subcutaneously injectable artificial hepatocyte growth factor (HGF) mimetic molecule using a fusion technology of cyclic peptides and protein engineering. They demonstrated in a mouse model that it improves liver fibrosis, lipid accumulation, and inflammation caused by non-alcoholic steatohepatitis (NASH). This research result provides an option for the development of NASH therapeutics as well as a technology for creating growth factor and cytokine mimetic molecules with improved pharmacokinetics.

Applied Microbiology International has announced that it has recruited 11 new Global Ambassadors from around the world.

- Recipient Associate Professor Lena Ho spearheads groundbreaking research to develop first- in-class therapeutics to target inflammatory diseases; Collaboration between 65LAB and Duke-NUS aims to advance promising innovation from academic institutions with potential to build new therapeutic companies from Singapore; S$1.85 million funding comprises US$1.5 million from 65LAB and US$350,000 from Duke- NUS' newly established incubator, LIVE Ventures

Researchers from the HeKKSaGOn Alliance – involved were scientists from Kyoto University, Osaka University and Heidelberg University (Germany) – synthesized a bio-inspired polymer for water purification. The polymer was designed to mimic phytochelatin, a plant protein that selectively captures and neutralizes harmful heavy metal ions. The hyperconfinement of the polymer enabled a flow-through system and effectively removed cadmium ions from contaminated water, making it safe to drink. The system was selective for heavy metals and provides a new way to remove specific contaminants from water.

Distinctive processes could provide hints on how to use next-generation materials

Using optical vortex enhances printing technology, shows promise in creating well-formed single ferrite crystals

A 100-year-old physics mystery may be close to being solved as a new study reveals structural changes in titanium-48’s nucleus

Mechanics and thermodynamics of (Mg,Fe)O grain boundaries under extreme pressure

Researchers at Tohoku University and the UK developed a model showing the ability of reconfigurable intelligent surfaces to redirect the propagation of radio waves, which could improve the signal.

Decoding dead stars’ “heartbeats”, Why do females live longer? DNA controller for molecular robots, Earliest twin quasars found. Read all in the latest Editor's Choice. Plus July's SciCom Coffee with A*STAR's Lisa Chong and get the early bird price to be in Asia Research News 2025.

- Achieved "Outstanding" Rating in the 2024 Research Project Evaluation for Research Institutions Directly Under the MSIT!

- DGIST invites Jon Hirschtick, co-founder of SolidWorks, to give a lecture - Hirschtick provides deep insights into CAD and AI technology advancements and future prospects

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University report in Small Methods the 3D imaging of a suspended nanostructure. The technique used is an extension of atomic force microscopy and is a promising approach for visualizing various 3D biological systems.

A team led by Osaka University discovered that the new organic molecule thienyl diketone exhibits high-efficiency phosphorescence, achieving a rate over ten times faster than traditional materials. This breakthrough provides new guidelines for developing rare metal-free organic phosphorescent materials, promising advancements in applications like organic EL displays, lighting, and cancer diagnostics.

In this study, the crystal structure of serpentine (antigorite) was investigated using first-principles calculations under pressure. The results showed that the structure and chemical composition of antigorite changed gradually under high pressure, and it is highly likely that water was released by these structural changes during the subduction process. It was shown that the changes in the modulated structure (polysome) reported in this study may explain the distribution of intermediate-depth earthquakes reported by observations.

Researchers at the Institute of Industrial Science, The University of Tokyo implement a genetic algorithm to automatically design phononic crystals with desired vibrational properties, which may help with future computer and communication devices

Sound velocities in lunar mantle aggregates at simultaneous high pressures and temperatures suggests the presence of garnet in the deep lunar interior

To form qubit states in semiconductor materials, it requires tuning for numerous parameters. But as the number of qubits increases, the amount of parameters also increases, thereby complicating this process. Now, Tohoku University researchers have automated this process, overcoming a significant barrier to realizing quantum computers.

The first-ever Lingnan-Yuanpei STEM Summer Academy, organised jointly by Lingnan University in Hong Kong and Yuanpei College of Peking University (PKU), held a seven-day Innovation and Entrepreneurship Training Camp-cum-STEM Competition from 22 to 28 June. Thirty of the best students from both universities formed five teams to compete on various innovative and entrepreneurial smart green technological projects. After a tight race, the project “Sustainable Green Building” team won the championship prize, and the chance to be nominated for the Lingnan University Entrepreneurship Fund, and will be put up for an application for seed or incubation funds.

We performed in situ X-ray observations of the unit-cell volume of SiO2 stishovite in a water-saturated system using a multi-anvil apparatus. The results revealed that the unit-cell volume expanded excessively at temperatures lower than 600°C, but it decreased with increasing temperature and time. Therefore, water dissolution into SiO2 stishovite is likely a metastable phenomenon and stishovite is unlikely to be a major water carrier, at least up to uppermost lower mantle conditions.

Approach could have applications for microchemistry, quantum dots

・In situ deformation experiments on olivine were performed using a high-flux synchrotron X-ray and a “mobile” multianvil apparatus at BL05XU, SPring-8. ・Transient creep of olivine aggregates follows the Burgers creep function at upper mantle pressures and temperatures. ・Time-dependent rheology of the shallow mantle observed in the late post-seismic deformation is explained by the Burgers model.

Researchers from Osaka University used theoretical calculations assessing electron orbital symmetry to synthesize new molecule designed to be both transparent and colorless while absorbing near-infrared light. This compound demonstrates the first systematic approach to producing such materials and have applications in advanced electronics. This compound also shows semiconducting properties.

Researchers from the Institute of Industrial Science, The University of Tokyo, have efficiently removed oxygen from high-oxygen-concentration titanium, which might help reduce the production cost of an otherwise versatile metal.

Theoretical simulations and synchrotron experiments reveal the hidden fingerprint of new magnets

The NSF Center for Molecularly Optimized Networks team, of which Professor Jian Ping Gong of the Faculty of Advanced Life Science and the Institute for Chemical Reaction Design and Discovery (WPI-ICReDD) at Hokkaido University is a member, has won a Horizon Prize from the Royal Society of Chemistry.

In interpersonal relationships, people sometimes perceive that the other person understands them. When people feel this way, they are more willing to engage with the other person, but the reasons for this were not well understood. This study reveals that the psychological process for this feeling largely depends on a reduction in prejudice towards the other person. The results of this study may help us understand the psychological process behind reducing discrimination.

Researchers from Osaka University used omnidirectional photoluminescence measurements to study the effect of carbon impurities in pure gallium nitride crystals. They found that the type of energy losses depends can switch at a critical value, which can help in the manufacture of more efficient devices.

Blue energy future, Off switch for brain cells, New Japanese lily species, Generative AI in motion, Economies take off with new airports and Braille-shaped electrodes for retinal implants. Read all in the latest Editor's Choice. Plus SciCom Coffee with Catriona Child.

A research group at Osaka University has developed an innovative positioning system that enhances the versatility and accuracy of drone-viewpoint mixed reality (MR) applications by aligning real and virtual world coordinates without predefined routes. By integrating visual positioning systems and natural feature-based tracking, this technology is expected to be applied to urban landscape simulation, maintenance, and inspection work.