Science

Researchers at The University of Tokyo grow a nanoscale layer of a superconducting material on top of a nitride-semiconductor substrate, which may help facilitate the integration of quantum qubits with existing microelectronics

A pathway that malfunctions in advanced non-alcoholic fatty liver disease could be fixed with the aid of spermidine, a compound naturally found in bodily cells and certain whole foods.

Scientists have uncovered how Coxsackievirus B3, the most common cause for viral heart inflammation, takes advantage of a specific heart sensor to trigger chronic inflammation that can lead to heart failure.

Giants in History: Malaysia’s first astrophysicist, Mazlan binti Othman (born 11 December 1951) was instrumental in launching the country’s first microsatellite, and in sending Malaysia’s first astronaut, Sheikh Muszaphar Shukor, into space.

Researchers from The Institute of Industrial Science, The University of Tokyo have developed a streamlined photo-uncaging system for photodynamic cancer therapy, using a pulse of light for tumor-specific activation of a cancer-fighting agent

A research group led by the Institute of Industrial Science, The University of Tokyo, finds that sensory neurons in human skin modulate melanocytes via the secretion of Repulsive Guidance Molecule B

The activity of deep-focus earthquakes, which increases with depths from ~400 km to a peak at ~600 km, is enigmatic because conventional brittle failure is unlikely to occur at elevated pressures. Our experiments showed that formation of thin weak layers filled with nano-crystalline olivine/wadsleyite, upon the pressure-induced phase transition of olivine, is the major cause of deep-focus earthquakes on the metastable olivine wedge in deep slabs.

Researchers found a new way to reduce carbon dioxide (CO2) emissions by wrapping copper nanocubes with an organic layer, solving instability and selectivity problems with copper nanocubes in catalysis, and improving how this electrocatalyst converts CO2 into organic molecules.

Scientists from The University of Tokyo formulated nonlinear, nonequilibrium energy dissipation relationships using methods from geometry to better understand the kinetics of irreversible chemical processes

Cellular structures called mitochondria depend on microproteins to assist and control the assembly of a protein chain that extracts energy from nutrients, according to a new study by scientists in Singapore.

Giants in History: Sir Mokshagundam Srinivasa Shastry Vishveshwarayya (15 September 1860 – 14 April 1962) is widely regarded as India’s most outstanding engineer.

A commentary in Nature Medicine advocates the proper application of artificial intelligence in healthcare and warns of the dangers when machine learning algorithms are misused.

The Memorandum of Understanding signed between The Ngee Ann Kongsi and Duke-NUS Medical School emphasises the need for more research as treatment and prevention options are currently limited for conditions such as Parkinson’s disease.

Demonstration of embodied cognition mechanisms in the brain could have implications for artificial intelligence.

An international research team led by scientists from Osaka Metropolitan University has developed a method to identify symmetries in multi-dimensional data using Bayesian statistical techniques. Bayesian statistics has been in the spotlight in recent years due to improvements in computer performance and its potential applications in artificial intelligence. However, this statistical approach requires complex calculations of integrals, which are often considered approximations only. In their new study, the research team successfully derived new exact integral formulas. Their findings contribute to improving the accuracy of methods to identify data symmetries, possibly extending their applications to wider areas of interest, such as genetic analysis.

Researchers at The University of Tokyo create a geometric representation of thermodynamic systems and apply it to self-replicating processes, which may help improve our understanding of the physical constraints of living organisms

Researchers at Hiroshima University are closer to identifying the molecular processes underlying how floods deprive plants of oxygen — and how to engineer hardier crops.

Scientists have quantified the glacier mass loss on the Kamchatka Peninsula; the accelerated loss in the region since the turn of the millennium is likely to increase in the short term.

Researchers from Osaka University have found that photoperiod variation in bean bugs is regulated by genes involved in maintaining circadian rhythm via the neurotransmitter glutamate. The discovery of this mechanistic link between the biological clock and seasonal variation may have important implications for seasonal adaptation in other animals, given the conservation of glutamate across many species.

The Gunflint Formation, which straddles Lake Superior’s northwestern shore, contains a treasure trove of geological clues about the evolution of life. After a recent geological reassessment of this area, a research team has unearthed new types of microfossils dating 1.9 billion years. The landmark discovery will help scientists pinpoint the timing and factors that ushered in the evolution of prokaryotes to eukaryotes.

The research team directed by H. Shimomoto and E. Ihara in Ehime University successfully developed a new Pd-based initiating system affording carbon–carbon main-chain polymers bearing end-functional groups. This achievement will contribute to progress in the field of polymer chemistry and will allow us to develop new types of functional polymers.

Researchers from Osaka University and collaborating partners detected unique fluorescence blinking patterns in experiments of electron transfer to single DNA molecules. They used these patterns to identify mRNA glioma point mutations in cell culture. The results of this work could help simplify surgical biopsies, enable real-time targeted therapy, and advance scientific understanding of cancer progression.

Researchers from Osaka University and collaborating partners used common nanofabrication procedures to fabricate versatile metal semiconductor superlattices. These superlattices exhibit a long-sought physical phenomenon—the anisotropic anomalous Hall effect at room temperature. This research will help improve the density of data storage, as well as the functionality of other technologies that also depend on advances in the microelectronics industry.

Osaka Metropolitan University scientists developed a simple, rapid method for identifying food poisoning-inducing bacteria based on color differences in the scattered light of composite structures consisting of gold, silver, and copper nanoparticles and polymer particles. Using these composites as test labels bound to specific bacteria, the researchers detected food poisoning bacteria E. coli O26, E. coli O157, and S. aureus as white, red, and blue scattered light, respectively, under the microscope. This new method enables simultaneous identification of multiple bacterial species within one hour, significantly shortening the usual 48-hour time requirement for conventional bacterial tests.

Two new approaches could help scientists use existing sequencing technology to better-distinguish RNA changes that affect how their genetic code is read.

A baby’s cry is a form of communication used to attract attention from adult caregivers, and every baby cries in a similar but distinct way. An international research team has studied the vocal behavior of baby mice, called pups, to determine how the age of the father affects the pups’ vocal communication and body weight development. Their study will help them better understand vocal development in human babies.

Osaka Metropolitan University researchers have successfully synthesized fumarate (fumaric acid), a raw material for unsaturated polyester resin, by combining carbon dioxide (CO2) with pyruvate (derived from biomass), using two biocatalysts: malate dehydrogenase and fumarase. Fumarate is currently used to make biodegradable plastic like polybutylene succinate from petroleum. However, this research has enabled the synthesis of fumarate without petroleum, consuming only CO2 and biomass-derived pyruvate.

A research group led by Professor Akitoshi Hayashi at the Osaka Metropolitan University Graduate School of Engineering has successfully developed a high-capacity capacitor, an energy storage device—using a solid electrolyte with high deformability—that can operate at high temperatures. With this discovery, high-capacity capacitors can now be made which do not require cooling, this increases their efficiency and allows for new suitable applications.

Two novel hypotheses have been proposed that address the “two-fold cost of sex”: one of the biggest enigmas in the evolution of sexual reproduction.

A research group led by Osaka University has found a new class of proteins in the red algae Cyanidioschyzon merolae that are involved in moving proteins across the membranes of chloroplasts – subcompartments that conduct photosynthesis within the cells of organisms such as plants and algae. These findings could be used to boost photosynthesis in several groups of algae that contribute considerably to marine biomass and are commercially farmed.