Science

Researchers at Kanazawa University report in Biophysics and Physicobiology how to optimize high-speed atomic force microscopy experiments on live cell membranes, so that moving objects like molecules can be properly followed from frame to frame.

The molecule is unusual and has ‘great potential’ in catalysis, conduction and other applications.

A research group led by Professor Yoshio Teki of the Osaka Metropolitan University Graduate School of Engineering has succeeded in developing a new pentacene derivative that is more than 100 times more photostable than TIPS-pentacene, a photostable pentacene derivative. Additionally, the team has further clarified the ultrafast excited state dynamics in this system. In the pentacene moiety of this system, we were able to demonstrate that the transition from the excited singlet state to the excited triplet state occurs ultrafast in the time region of a 10-13 seconds. In purely organic materials without heavy atoms such as rare metals, such intersystem crossing usually occurs on time scales longer than 10-9 seconds. The empirical results of this study are expected to be applied as a method for stabilizing and developing light-unstable materials in the future.

Scientists have revealed the genetic structure and diversity, and inferred the population history, of the wild house mouse across Europe and Asia.

Giants in History: Hideki Yukawa (23 January 1907 – 8 September 1981) was awarded the Nobel Prize in Physics in 1949 for predicting the existence of the pi meson subatomic particle

Potential of a novel therapeutic strategy for rheumatoid arthritis by UHRF1 stabilization We identified an epigenetic regulator UHRF1 that suppresses various pathogeneses in rheumatoid arthritis. The UHRF1 expression level in synovium showed a negative correlation with the severity of pathogenesis in patients with rheumatoid arthritis and mouse arthritis models. In addition, stabilization of the UHRF1 expression achieved improvement of the arthritis pathology. Our results indicate that the stabilization of the UHRF1 protein is a potential therapeutic strategy for rheumatoid arthritis patients.

Researchers at the Institute of Industrial Science, The University of Tokyo studied the anomalous properties of amorphous solids, including glasses, using computer simulations, and found a common vibrational mechanism underlying them, which may help control the glass properties

An international team of researchers, led by Changfang Zhao, from Nanjing University of Science and Technology, has developed a novel lightweight, high toughness auxetic structure made from plastic composite laminates. The auxetic structure may be used for constructing primary structures in the transport industry, such as electric vehicles, to maximize fuel efficiency.

Scientists have revealed two enzymes that regulate protein degradation of proteins in the cell membrane of plants, and established the roles they play in plant growth and development.

Giants in History: Known for her pioneering contributions to bio-organic chemistry, Darshan Ranganathan (4 June 1941 – 4 June 2001) is considered India’s most prolific chemist.

Scientists have described the youngest therizinosaur fossil from Japan and the first in Asia to have been found in marine sediments.

Dr. Nishikawa at Osaka Metropolitan University focused on the Kondo effect on minimal ferrimagnetism and attempted to elucidate it theoretically. As a result, they found that the Kondo effect occurred via multiple "quantum entangled states" depending on temperature and other factors. They also found that the Kondo effect suppressed electrical conductivity through minimal ferrimagnetism, when usually it is amplified in many other cases.

Giants in History: Known as Mr. Natural Rubber, chemist and researcher B. C. Shekhar (17 November 1929 – 6 September 2006) introduced a number of technical innovations that helped put Malaysia’s natural rubber industry on the world map.

Researchers at Kanazawa University in collaboration with teams from Toyama Prefectural University and BioSeeds Corporation report in ACS Applied Materials & Interfaces the identification of a molecule with enhanced antiproliferative activity in cancer cells. The underlying biomolecular mechanism is the inhibition of an enzyme that is overproduced in several types of cancer.

Researchers in Japan demonstrated the benefits of a new non-radioactive, neutral negative staining reagent by imaging viruses at nanometer-scale.

Tetraphenylammonium, with all four hydrogens of ammonium (NH4+) replaced with benzene rings, has neither been discovered in nature nor chemically synthesized, calling into question whether it could exist. Here, we succeeded in synthesizing tetraphenylammonium for the first time, demonstrating its stable existence. The synthetic strategy used in this study, radical coupling, may be applicable to the synthesis of various related ammoniums with high structural novelty.

Scientists have synthesized the first belt-shaped molecular nanocarbon with a twisted Möbius band topology—a Möbius carbon nanobelt—that paves the way for the development of nanocarbon materials with complex topological structures.

Structural color printing creates new pathways for medical diagnostics and miniaturized sensors

Giants in History: Palaeontologist Yichun Hao (1920 – 2001) co-authored the first Chinese textbooks on palaeontology and micropalaeontology.

Researchers from the Osaka Metropolitan University Graduate School of Engineering have successfully developed a new technique allowing them to observe gas molecules packing into metal-organic frameworks (MOF) using infrared spectroscopy. Their innovation was to measure polarized light absorption of guest molecules in a MOF film to deduce molecule alignment using this common piece of lab equipment. This method is the first to show guest alignment and does so in real-time, while using an accessible and easily adoptable experimental setup. A short video (4 min) recreating their spectrometer modifications can be found in the Reference section.

The new multi-tasking weather sensor simultaneously measures rain volume and wind speed. Incorporating machine learning to analyze the output data, a single sensor can provide localized weather data in a timely manner, improving disaster preparedness.

Researchers from the Institute of Industrial Science, The University of Tokyo, develop a novel method for more accurate prediction of local rainfall patterns

Molecular robots work cooperatively in swarms, LED lights made from rice husk, Muonic x-rays safely see inside samples, Making a luminescent material shine brighter and How to counter vaccine hesitancy, Read all in the May Editor's Choice and this month's Asia Research News 2022 magazine pick - Absorbing impact: Inside the Head of a Woodpecker.

Giants in History: Thai physician and conservationist Boonsong Lekagul (15 December 1907 – 9 February 1992) made major contributions to the preservation of his country’s wildlife by founding organizations including the Association for the Conservation of Wildlife (ACW), writing about Thailand’s natural heritage, and supporting conservation initiatives.

Giants in History: Ground-breaking cancer researcher Kamal Jayasing Ranadive (8 November 1917 – 11 April 2001) advanced the understanding of the causes of leukaemia, breast cancer and oesophageal cancer through the use of animal models.

A Hong Kong Baptist University (HKBU) collaborative research study has revealed that certain gut microbial enzymes mediate the reactivation of triclosan (TCS) from its inactive glucuronide metabolite. TCS is an antimicrobial agent commonly used in a wide range of consumer products, and it is associated with the development of colitis.

Giants in History: Little is known about Ali, a teenager from Sarawak, Malaysia, who was chief assistant to the famous naturalist Alfred Wallace.

Hokkaido University researchers have shown how chronic pain leads to maladaptive anxiety in mice, with implications for treatment of chronic pain-related psychiatric disorders in humans.

Researchers overcome computational limitations to predict the starting materials of multi-step reactions using only information about the target product molecule.

Examination of endangered species’ stem cells unveils ancient genetic links between mammals.