Science

New insights into the role of a protein in the nerve cells of flies could help unravel the role of a related human protein in common cancers.

Scientists have uncovered new details of how ice forming below the ocean surface in Antarctica provides cold dense water that sinks to the seabed in an important aspect of global water circulation.

Pyroxenes are a major group of rock-forming minerals. Osaka Metropolitan University scientists investigated the iron ion status of a calcium-rich pyroxene, using Mössbauer spectroscopy on thin sections of single crystals. The study revealed that in pyroxene crystals consisting of roughly 50% calcium, the tensor that determines the ratios of iron ions at the Mössbauer spectral peaks in the M1 sites—one of two types of cation positions in the pyroxene crystal structure—is independent of the iron content but dependent on the calcium content. The research findings have clarified one of the physical properties of pyroxenes, facilitating detailed future analysis of iron using Mössbauer spectroscopy on mineral flakes.

A long-term experiment aboard the International Space Station has tested the effect of space radiation on mouse embryonic stem cells. Their findings will contribute to helping scientists better assess the safety and risks related to space radiation for future human space flights. The findings are published in the journal Heliyon.

Chemists in Japan, Canada and Europe have uncovered flaws in the surface structure of cellulose nanocrystals—an important step toward deconstructing cellulose to produce renewable nano-materials relevant to biochemical products, energy solutions, and biofuels.

Researchers from Osaka University have found that the Vibrio cholerae colonization factor TcpF forms a flower-shaped trimer to specifically bind to the minor pilus protein TcpB resulting in secretion by the type 4 pilus secretion system into the extracellular space. This finding could help lead to the development of a novel anti-adhesive drug that selectively interrupts the TcpF-TcpB interaction, which may replace antibiotics in the treatment of cholera.

Researchers from Osaka University have developed a computational analysis tool called CAPITAL for comparative analysis of single-cell RNA sequencing data with complicated branching trajectories. As cells undergo a dynamic process, they can be placed on a “pseudotime trajectory” to analyze the gene expression changes throughout the process. While previously only straightforward linear trajectories could be compared, CAPITAL is proven to be able to accurately compare branching trajectories, significantly advancing the field of high-throughput single-cell sequencing.

Osaka Metropolitan University scientists have created a novel thermoresponsive polymer by adding divalent cations to polymers and water solvents. They also succeeded in controlling thermoresponsive properties by changing the type and mixing ratio of ionic species. This new polymer type is expected to be applied as an analytical reagent for ion-sensing devices and as a material for drug delivery systems.

Puzzling image from the James Webb Space Telescope explained in two new studies

Osaka University researchers developed a power generation system based on osmotic flow of ions through a membrane riddled with tiny nanopores. By optimizing the size and distribution of the pores, the team demonstrated a way to obtain clean energy from the oceans.

Researchers at The University of Tokyo simulated fractures in amorphous materials due to both cyclic fatigue and constant stress using course-grained dynamics, and demonstrated various failure modes, which can help improve reliability of materials

The SARS-CoV-2 Omicron variant escapes the immune response better than its coronavirus ancestors, but has also facilitated our transition to a society that can live with COVID-19.

Researchers from Osaka University and collaborating partners enhanced DNA detection in silicon nitride nanopores by means of a water–glycerol viscosity gradient. Use of common chemistry under electrochemical flow enabled straightforward detection of individual DNA molecules. With further development, the results of this work could dramatically speed up and lower the cost of genomic sequencing, and facilitate unprecedented integration with compact electronics.

Osaka Metropolitan University scientists have successfully synthesized 3-hydroxybutyrate, a raw material for poly-3-hydroxybutyrate (PHB)—a strong, water-insoluble, biodegradable plastic used for packaging materials—from acetone and CO2. With a visible light-driven catalytic system utilizing sunlight and two biocatalysts, the researchers achieved a high conversion yield of about 80%. Mimicking natural photosynthesis, this study artificially reproduced a light reaction involving sunlight and a dark reaction fixing CO2 to synthesize the raw material for PHB. The finding is expected to contribute to solving the plastic waste problem and to reducing CO2.

Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are an algorithm that can detect epilepsy from brain scans, the first National Robotics Tournament in Vietnam, and how being lonely or depressed can accelerate aging.

Researchers from Osaka University revealed that the surface electronic structure of topological insulators varies according to its surface atomic structure, even though it was believed to have been protected by the symmetry of the electronic structure inside the crystal and is therefore unaffected by differences in surface atomic structure. This work offers a new means of minimizing the power consumption and increasing the speed of next-generation technology.

Giants in History: Joo-myung Seok (November 13, 1908 – October 6, 1950) was a Korean butterfly entomologist who made important contributions to the taxonomy of the native butterfly species in Korea.

Linked lanthanides shine light on crystal engineering, New technique reveals hidden genome, Red, white and blue alerts for dangerous bacteria & Windows gain competitive edge over global warming. Read all in the September's Editor's Choice plus this month's Asia Research News 2022 magazine pick - Floating sensors to gather ocean data.

Reviewed Preprint authors from underrepresented backgrounds and countries with limited funding can now apply for an award to support their research and career.

Research performed on human blastoids, a research model of an early embryo built out of stem cells, may allow scientists to understand better what causes birth defects and lost pregnancies, and so prevent them. But such research is also ethically fraught, warn bioethicists, due to differing beliefs on whether the blastoid possesses sentience or has the potential to do so.

Lingnan University (LU) in Hong Kong highly values research and knowledge transfer that generate social impact and demonstrate care for the community. LU honoured 72 LU faculty members for their outstanding performance in research and contributions to knowledge transfer in raising the community’s quality of life and contribution to society during the 2021/22 and 2022/23 academic years.

Osaka University researchers showed how to use laser beam interference to construct chiral structures. By using computer simulations, they were able to predict the final light pattern and optical radiation force distribution of any collection of light sources. This work may lead to cheaper optical devices and sensors.

Scientists have pinpointed a protein in lysosomes that is involved in recycling a crucial fatty component of cell membranes to keep cells healthy.

Hokkaido University researchers find a new way of producing the industrially important propylene that is more energy efficient than existing approaches—and in the process turns carbon dioxide into another usable resource. Their pioneering catalyst design thus contributes to the carbon neutralization of the petrochemical industry.

Researchers at The University of Tokyo grow a nanoscale layer of a superconducting material on top of a nitride-semiconductor substrate, which may help facilitate the integration of quantum qubits with existing microelectronics

A pathway that malfunctions in advanced non-alcoholic fatty liver disease could be fixed with the aid of spermidine, a compound naturally found in bodily cells and certain whole foods.

Scientists have uncovered how Coxsackievirus B3, the most common cause for viral heart inflammation, takes advantage of a specific heart sensor to trigger chronic inflammation that can lead to heart failure.

Giants in History: Malaysia’s first astrophysicist, Mazlan binti Othman (born 11 December 1951) was instrumental in launching the country’s first microsatellite, and in sending Malaysia’s first astronaut, Sheikh Muszaphar Shukor, into space.

Researchers from The Institute of Industrial Science, The University of Tokyo have developed a streamlined photo-uncaging system for photodynamic cancer therapy, using a pulse of light for tumor-specific activation of a cancer-fighting agent

A research group led by the Institute of Industrial Science, The University of Tokyo, finds that sensory neurons in human skin modulate melanocytes via the secretion of Repulsive Guidance Molecule B