Science

Researchers from The University of Osaka found that mass photometry can accurately distinguish full and empty rAAV particles in cell lysates and conditioned medium, without prior purification. This convenient and rapid approach is likely to improve manufacturing of rAAV-based gene therapy products by accelerating the screening steps.

A research team from The University of Osaka has made a significant breakthrough in cancer radiotherapy by identifying conditions under which carbon ion beams—delivered at ultra-high dose rates (uHDR)—can protect normal cells. This phenomenon, known as the “FLASH effect,” could revolutionize cancer treatment by reducing side effects and improving patients’ quality of life.

Scientists at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University have captured real-time footage showing how a key hormone receptor activates genes, offering a clearer view into one of the most fundamental Kaprocesses in biology.

How does obesity affect insulin production? Researchers at Tohoku University are shining light on new stages of the ERK pathway.

The rules about magnetic order may need to be rewritten. An international team of researchers found that it was possible to turn a non-magnetic material into a magnetic material by slicing it into thin films.

Researchers at Tohoku University have developed a data-driven AI framework that gives scientists a head start by suggesting ideal candidate materials.

Smart neural electrode, "Rhinoceros beetle" robot, Halting the thief of sight, Together at last & Lighting hardy plants. Plus latest SciCom Coffee talk. Read all in the latest Editor's Choice.

The power conversion efficiency of all-organic solar cells was doubled through the development of novel organic electrodes that can be fabricated using a moderate process.

Researchers found a strategy to create catalysts that make the production of hydrogen for clean fuel more efficient and affordable.

- Selected for both the Super Gap Startup 1000+ Project and the Strategic Technology Research Outcome Commercialization Project - Proved its self-driving robotics technology based on precision sensors... with the aim of IPO in 2028

These dynamically adjustable water-based lenses have many potential future uses, from classrooms and research labs to cameras and wearable gadgets.

Researchers at Tohoku University explored a colloidal crystal model to produce specific polymorphs, required for use in materials science and pharmaceuticals.

New light-powered DNA detection enables more accessible, affordable genetic analysis

Professor Carlos M. Duarte, Ibn Sina Distinguished Professor of Marine Science, King Abdullah University of Science and Technology (KAUST), has been awarded the Japan Prize. Second time a KAUST scientist receives the award.

Shin-Etsu Chemical and Hokkaido University have developed system for the production of lipid nanoparticles (LNPs) that incorporates a microfluidic device.

Why does dementia affect more women than men? To help solve this mystery, researchers uncovered a new risk factor: age of menopause onset.

Back in 2021, MLB decided to crack down on pitchers’ use of resin to grip the ball better. As a result, the average spin of a pitch dropped, and batters hit more balls. A team of researchers has explored the phenomenon behind this.

Real-time X-ray analysis reveals how single atoms dynamically adapt to boost CO2-to-CO conversion.

Scientists at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University and colleagues have developed a promising new approach to cancer treatment. By using tiny, naturally occurring particles called extracellular vesicles (EVs), they have created a way to boost the body’s immune system to fight tumors more effectively. This breakthrough could lead to more targeted cancer therapies with fewer side effects.

Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrates a novel approach for nanoscopic profiling of small extracellular vesicles (sEVs) using high-speed atomic force microscopy (HS-AFM) videography. This pioneering method provides an unprecedented level of detail in characterizing sEV subpopulations, offering new insights into their biological roles and potential applications in disease diagnostics.

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in "Nature Communications" how the targeted suppression of lysosome function may lead to brain cancer therapy.

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University and colleagues have achieved a major breakthrough in understanding sperm DNA packaging. Using high-speed atomic force microscopy (HS-AFM), they captured the real-time process of protamine (PRM)-induced DNA condensation, providing critical insights into fertility, genome stability, and future applications in medicine. Their findings are published in "Nucleic Acids Research".

How the core-mantle differentiation shaped volatile elements in the Earth

FLUID, an open-source, 3D-printed robot, offers an affordable and customizable solution for automated material synthesis, making advanced research accessible to more scientists.

From harmful to helpful; researchers at Tohoku University and Hokkaido University have developed a record-breaking method to efficiently convert carbon dioxide into a fuel source.

New machine learning model cuts fluid simulation time from 45 minutes to 3

A genomic study of hydrogen-producing bacteria has revealed entirely new gene clusters capable of producing large volumes of hydrogen.

Researchers from the Institute of Industrial Science, The University of Tokyo, discover brand new one-dimensional diffraction patterns in two-dimensional nanomaterials, with exciting implications

A researcher from The University of Osaka shows that human tissue can be used to process data and perform computational tasks

A novel method to improve the photoluminescent efficiency of metal clusters has been developed – which could potentially be used in applications such as bioimaging or display technologies.