Peer Reviewed

New simulator and computational tool generate realistic “virtual tissues” and map cell-to-cell “conversations” from spatial transcriptomics data. The tools could accelerate AI-driven discoveries in cancer, brain disorders and precision medicine by revealing which genes control how cells interact.

A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of inducing antigen-specific regulatory T cells (Tregs), the immune cells that play a central role in suppressing excessive immune responses. The findings, now published in Drug Delivery, may pave the way for next-generation therapies for autoimmune and allergic diseases, where unwanted immune activation must be precisely controlled.

A new species of pitcher plant found only on Palawan Island is already at risk of extinction due to frequent severe weather conditions and human encroachment.

Why are gourmets seemingly able to detect subtle nuances in taste that others miss? Researchers at Tohoku University have uncovered part of the answer by demonstrating that taste sensitivity can be enhanced through learning.

A wearable sensor enables real-time monitoring of disinfectant exposure on skin and plant leaves, advancing health, agriculture, and environmental safety.

Researchers from the Institute of Industrial Science, The University of Tokyo develop an artificial intelligence framework for designing new inorganic materials with humanlike reasoning

Hiroshima University research shows that a portable heart monitoring device can detect fetal distress earlier and sharply improve newborn survival rates in low-resource environments.

A joint team from UOsaka has uncovered the core principles of the loss maximization in rotor-driven gas-liquid two-phase flows. Performing numerical simulations on the supercomputer "SQUID", they identified the causes as direct collisions between the rotor and the liquid surface and pressure imbalances around the rotor. The findings suggest that, in a resonant state, the enhanced fluid motion is drawn toward the front of the rotor, and the flow instability is intensified behind it. The insights from this research would open the possibility of improving energy efficiency, enhancing reliability and lifespan, and providing new design guidelines for various industrial applications.

Reagent-free (photo)electrochemical systems effectively breakdown cobalt–organic complexes while simultaneously recovering cobalt, presenting a promising strategy for advanced wastewater treatment and resource recovery.

Researchers have discovered a previously unknown marine fungus that kills toxic algae known to pose a health risk to humans

A new regional assessment shows that Southeast Asia is a major net source of greenhouse gases, with land-use change and rising fossil fuel use overwhelming natural carbon sinks, reservoirs that store carbon-containing chemical compounds for a long period.

Using mobile phone traces, transit data, and spatial modelling, SUTD researchers produced one of Singapore’s most detailed district-level maps of transport emissions that offers new insights into how urban form shapes daily mobility.

First visible ‘time crystal’ developed by WPI-SKCM² members, advancing the institute’s goal to engineer novel forms of matter

In a new Nature Physics study, researchers created particle-like so-called “vortex knots” inside chiral nematic liquid crystals, a twisted fluid similar to those used in LCD screens. For the first time, these knots are stable and could be reversibly switched between different knotted forms, using electric pulses to fuse and split them.

Researchers developed a highly selective membrane that efficiently separates carbon dioxide from other gases, supporting cleaner energy and industrial processes.

Mutated baker’s yeast at the forefront of alternative 2,3-butanediol production methods

A Filipino-led team of international researchers has developed a physics-based algorithm that could train AI to greatly improve weather forecasts.

Researchers at Tohoku University found the key to taming electrochemical reactions so they don’t produce rogue byproducts instead of valuable fuels.

Researchers create a stem cell medium for canine stem cells that doesn’t contain any human components

Over 10 years of monitoring

A newly discovered promoter element “start” points to a shared regulatory syntax for controlling transcription initiation in bacteria, archaea, and eukaryotes.

Sometimes the simplest solution is the best one. This research shows how exposing a single active site has huge implications for producing green energy.

The integration of high-dimensional omics data reveals that xylem differentiation programs have undergone simplification rather than elaboration, establishing a model of “reductive evolution” in seed plants.

Scientists used a 3D-printing approach to pattern hydrophobic barriers inside hydrophilic filter paper. These barriers, designed in different geometries, guide liquids along precise paths and shape their flow behavior, demonstrating effective use in mixing, gradient generation, and two-phase separation within miniaturized systems.

Researchers from The University of Osaka have developed a novel reverse genetics system to study norovirus, the leading cause of gastroenteritis. This efficient system can generate infectious viral particles by simply injecting viral genetic material into zebrafish embryos. They were able to alter the genetic material to create modified viruses, enabling the evaluation of antiviral drugs and novel vaccine development. The advances provided by this new system will have a significant effect on public health.

A scientist has solved the conundrum of why robots struggle to pick tomatoes

Listening to the "whispers" of electrons and crystals has lead to a quantum discovery with terahertz light that could help us advance technological innovations and life science research.

Scientists have developed a new computational tool that maps multi-gene pathways more comprehensively than ever before. The study uncovered a previously unknown protein pathway that, when blocked, kills blood cancer cells. The discovery could lead to new therapies for patients with drug-resistant blood cancers.

Researchers from The University of Osaka found migration of glucose and fructose from the blood to saliva drives oral microbiome dysbiosis in patients with type 2 diabetes, increasing the development of dental caries. This suggests that glycemic control could be an effective strategy for controlling dental caries in this population.

Underlying cause of illness at high altitudes examined at the summit of Mt. Fuji