Peer Reviewed

Every bit of technology fails eventually, whether time, wear-and-tear, adverse conditions, or perhaps a mixture of all three are the cause of its demise. Yet predicting when technology might fail is notoriously difficult. When designing equipment for clear-energy systems, engineers often over compensate for this by designing it to withstand more stress than needed. This generates waste, and can sometimes inadvertently increase the wear and tear on materials. Now, an international research team has developed a way to more accurately predict how long mechanical-equipment used in green technology will last, potentially leading to more efficient design processes.

Elastic fiber component level in human hepatic stellate cells may predict liver damage

Researchers at National Taiwan University have uncovered, for the first time at atomic resolution, how the human proteasome recognizes branched ubiquitin chains. This breakthrough reveals a multivalent decoding mechanism that enhances protein degradation accuracy and speed.

Rechargeable batteries get a supercharged boost from newly developed RAMOFs that don’t break down in water, which was previously a major problem for this material.

The origin of the elusive preference of copper chalcogenides for selectively converting carbon dioxide (CO2) into formate has long puzzled researchers. Researchers at National Taiwan University have identified a charge-redistribution mechanism that resolves this long-standing debate, providing fundamental insight into the basis of their exceptional selectivity.

A team of researchers from Academia Sinica and National Taiwan University has identified the Drosophila Cul2 substrate adaptor DmZer1 as a key regulator of protein quality control, acting at the intersection of two major cellular “cleanup systems”: autophagy and the ubiquitin-proteasome system. Interestingly, lowering DmZer1 levels activates the Cnc/Nrf2 stress-response pathway, which in turn strengthens the cell’s ability to defend itself against oxidative stress.

Sonochemical degradation of carbon tetrachloride was found to increase in the presence of alcohols

Sea salt aerosols are an important, chemically-reactive contributor to air quality when their components interact with the already polluted city air, particularly in Metro Manila.

Slow earthquakes have been discovered to exhibit anomalously slow, long-lasting, and small slips, adjacent to regular earthquakes where we sometimes feel catastrophic vibration. However, no one knows the reason why they show such strange characteristics. In a study published in a scientific journal Nature Communications, researchers at The University of Osaka succeeded in experimentally reproducing the multiple features of slow earthquakes in the lab and suggested the grain-scale origin of them based on their direct observations.

- Professor Ko Jae-won’s research team at DGIST uncovers key role in signal transmission between neurons and memory formation - Establishing the molecular foundation of learning and memory, expected to treat dysfunctional brain disorders, such as autism and dementia

- Joint research team from DGIST, KAIST, POSTECH, Kyung Hee University, and Kongju National University develops a next-generation, eco-friendly heating and cooling technology that operates without electricity - The research result was selected as the cover study in ‘Advanced Materials’

- The DGIST research team, led by Professors Eom Ji-won and Ko Jae-won, identified the cause: a protein abnormality in autistic patients that disrupts brain signal transmission and leads to communication difficulties. - Identifying the ‘Switch inside Brain’ linked to autistic symptoms, expected to provide clues for developing future treatments for mental illness.

- Enables high-resolution Doppler estimations through signal extrapolation without complex computation... Expected to enhance unmanned system performance

Scientists turn essential oil compounds into durable yet decomposable polymers.

Researchers from The University of Osaka created a reagent for important building-block molecules with an abundant main-group element, gallium. These early findings show that an organic gallium compound can display transition-metal-like reactivity under light irradiation. Using common main-group elements like gallium offers a new way to make sustainable catalysts that do not need expensive transition metals, which are environmentally damaging and vulnerable to supply disruption.

A research group led by Associate Professor Islam MD Parvez and Professor Kenji Hato of the Graduate School of Agriculture at Ehime University has developed "Hort-YOLO," a real-time monitoring system for horticultural crops. This system is an advanced object detection network focused on accurate and context-aware analysis of crops, and simultaneously achieves a balance between annotation speed and scalability of supervised learning, making it practical for deployment in real-world environments.

What if a surface could instantly switch from sticky to slippery at the push of a button? By using electricity to control how ions and water structure at the solid liquid interface of self-assembled monolayers of aromatic molecules, researchers at National Taiwan University have created a molecular-scale adhesion switch that turns attraction on and off.

Researchers from The University of Osaka developed mirror-image semiconductor polymer molecules for organic solar cells. The new acceptor molecules prevent recombination of electrons and holes by generating currents with spin-polarization of about 70% in which one electron spin dominates. Solar cells containing the new acceptors showed three times higher efficiency than the non-mirror-image version. Using mirror-image acceptor molecules provides a new way of increasing efficiency in clean energy technology.

A new scoring system using common clinical parameters accurately identifies chronic liver disease patients with a significantly increased risk of developing liver cancer. This tool acts as a universal predictor, helping doctors guide surveillance recommendations for patients with diverse liver diseases, including metabolic dysfunction associated steatotic liver disease.

A commoning approach for democratic, community-centric weather modification

Researchers from The University of Osaka fabricated a nanopore surrounded by a gate as a cooling system with enhanced efficiency for semiconductor chips. Applying a voltage to the gate induces the flow of ions through the nanopore. Creating a salt gradient makes the ion flow unidirectional. Heat is dragged along with the ions, resulting in heat transfer. Changing the applied voltage from negative to positive switches the system from cooling to heating.

Researchers from Japan have unveiled a comprehensive dataset detailing the psychological and social responses of Japanese adults to the COVID-19 pandemic. Spanning 30 survey waves from January 2020 to March 2024, the open dataset captures how Japanese adults’ risk perception, preventive behaviors, policy attitudes, views toward foreigners, and psychological distress evolved over more than four years of uncertainty. Published as a data paper in Data in Brief, this resource is now openly accessible to the global community.

Superconductive materials can conduct electricity with no resistance, but typically only at very low temperatures. Realizing superconductivity at room temperature could enable advanced, energy-efficient electronics and other technologies. Now, an international research team is one step closer to such an achievement.

Researchers from National Taiwan University Hospital and collaborating institutions have demonstrated that finerenone, a new-generation nonsteroidal mineralocorticoid receptor antagonist (MRA), significantly reduces the risk of death and major heart and kidney events compared with spironolactone in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D).

Researchers from the Institute of Industrial Science, The University of Tokyo detect the motion of hydrogen atoms in palladium at low temperatures using channeling nuclear reaction analysis

Researchers have created a special culture medium that allows dog stem cells to stably differentiate into functional heart muscle cells complete with contractions

The Philippines remains mired in import dependence despite years of government support.

When labelled scans are scarce and hospitals collect images in different ways, a new training recipe developed by SUTD researchers helps segmentation AI keep its bearings across domains without needing more annotations.

Physicists at The University of Osaka have unveiled a breakthrough theoretical framework that uncovers the hidden physical rule behind one of the most powerful compression methods in laser fusion science — the stacked-shock implosion. While multi-shock ignition has recently proven its effectiveness in major laser facilities worldwide, this new study identifies the underlying law that governs such implosions, expressed in an elegant and compact analytic form.

Scientists from National Taiwan University and the National Institutes of Applied Research of Taiwan develop a rapid and accurate microfluidic device that generates precise drug gradients and outperforms manual dilution, enabling reliable multi-drug screening for high-throughput and personalized medicine.