Medicine & Healthcare Pharmaceutical sciences

News

After intravenous injection into mice, STING-lipid nanoparticles (red) transported through blood vessels(green) accumulate in the liver (Takashi Nakamura, et al. Journal for ImmunoTherapy of Cancer. July 2, 2021).
17 Sep 2021
A specially designed lipid nanoparticle could deliver immune-signaling molecules into liver macrophage cells to overcome resistance to anti-tumor immunotherapy.
Schematic representation of effects of AHR agonists.
10 Sep 2021
Researchers have identified a potential reason why lower numbers of COVID cases have appeared amongst smokers compared to non-smokers, even as other reports suggest smoking increases severity of the disease.
02 Sep 2021
Researchers at Kanazawa University describe in Scientific Reports the identification of small compounds that can regulate the cellular production of extracellular vesicles — nanocontainers transporting biomolecules between cells. Such compounds hold promise for use in therapies for various diseases.
A suspension of lipid nanoparticles synthesized from the novel lipomer AA03-DL-10. Photo by Takuya Isono.
30 Jul 2021
Testing a large library of compounds reveals an easy-to-make lipid that can carry genetic code into the lung to treat disease.
Survival Curves
23 Dec 2020
A stress response of mitochondria, the part of our cells that produce energy to power bodily functions, is important to a longer life. A team of scientists from Osaka City University, Japan, searched through a chemical “library” of existing drugs to find one that can activate this stress response in the worm Caenorhabditis elegans. They found that an anti-hypertension drug called metolazone prolongs C. elegans lifespan, marking the first step in developing anti-aging pharmaceuticals.
28 Sep 2020
Researchers from the University of Tsukuba demonstrate that the hypnotic and teratogenic effects of thalidomide are separable. Thalidomide is a medication with several different effects, one of which is promoting sleep in the context of insomnia. In a new study, researchers from the University of Tsukuba have discovered that thalidomide exerts its hypnotic effects through mechanisms distinct from those for the drug’s notorious teratogenicity. These are striking results showing how thalidomide induces sleep independently of its known effects on the teratogenic cereblon pathway. These findings could be helpful in developing novel thalidomide-like hypnotic drugs without thalidomide’s teratogenic effects. The study was published in the scientific journal Proceedings of the National Academy of Sciences of the United States of America.
18 Sep 2020
Drugs tackling chronic myelogenous leukemia have completely transformed prognoses of patients over the last couple of decades, with most cases going into remission. But drug resistance can occur, leading to relapses. Targeting the lipids involved in regulating part of a leukemia stem cell’s life span offers a potential second route to defeat the disease—and solid tumorous cancers as well.
20 Aug 2020
A new catalyst design enables unprecedented control over the modification of fatty acid derivatives that opens the door to creating useful substances in a green and efficient manner.
19 May 2020
Scientists from Hong Kong Baptist University (HKBU) have developed a novel technique that can produce pure therapeutic drugs without the associated side effects.
brain memory concept
12 Jan 2020
The drugs helped mice and humans recall long-term object memories.
ACS Catalysis, Catalyst, In Su Lee, POSTECH, School of Life Sciences, UNIST, Yoon-Kyoung Cho
26 Aug 2019
A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has introduced an artificial catalytic reactor that can take control of chemical reactions inside living cells, as desired.
Asia Research News Logo
26 Apr 2019
BDP Week 2019 in China enjoys unparralleled industry support and is known for generating knowledge, creating business opportunities, and bringing innovative ideas to the table.

Events

09 Dec 2020 to 11 Dec 2020
Singapore's long-running Pharmaceutical Manufacturing Industry learning and networking event, featuring a stellar profile of C-suite experts and firms.
03 Nov 2020 to 05 Nov 2020
Your go-to event to reach out to key decision makers in the pharmaceutical industry. The event will be delivered digitally from 3-5 November 2020.
03 Jul 2019 to 05 Jul 2019
Asia's leading pharma industry event

Researchers

My research background covers multidisciplinary fields such as Pharmaceutics, Cancer Nanomedicine, Bioengineering and Organ-on-a-chip platforms. My current research focuses on the development of dynamic biological barriers on a chip such as blinking human cornea on a chip.