Nanotech

A new technique allows researchers to map how the cellular “skeleton” adapts to external stress.

Researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University report in Nature Communications that TMEM16F, a transmembrane protein that facilitates the passive movement of phospholipids and ions across membranes, explores a larger conformational landscape than previously thought to perform its unique functions. The finding refines our molecular understanding of crucial physiological processes such as blood coagulation and COVID-19 pathogenesis, and highlights the importance of probing membrane proteins in native-like environments.

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University report in Nature Communications a high-speed atomic force microscopy study of the structural dynamics of sodium ion channels in cell membranes. The findings provide insights into the mechanism behind the generation of cell-membrane action potentials.

Research by Assistant Professor Edison Ang Huixiang and his team from National Institute of Education/Nanyang Technological University Singapore

SUTD researchers developed an advanced system of breast cancer cell detection with improved speed and sensitivity, using a viral mechanism to enhance the tool’s sensing accuracy.

Riding the momentum of the environment-aware agenda, SUTD researchers were part of an international collaboration that developed a sustainable approach to discover and identify materials for next-generation electronics.

Researchers at Kanazawa University report in Frontiers in Molecular Biosciences a computational method to predict the placement of proteins on AFM substrates based on electrostatic interactions.

Researchers from Osaka University investigated the thermal energy changes across nanopores that allow the selective flow of ions. Switching off the flow of ions in one direction led to a cooling effect. The findings have applications in nanofluidic devices and provide insight into the factors governing ion channels in cells. The nanopore material could be tailored to tune the cooling and arrays could be produced to scale up the effect.

- Doctor Heo Su-jin and Professor Jang Jae-eun’s research team from DGIST developed an ultra-small nano vacuum tube transistor that stably operates in atmospheric pressure without being affected by extreme environments.

The shortlist for the Applied Microbiology International Awards 2023 has now been announced. The AMI Awards programme is designed to celebrate the brightest minds in our field and promote the research, group, projects, products and individuals who continue to help shape the future of applied microbiology.

Researchers at Osaka Metropolitan University have succeeded in printing uniformly sized droplets with a diameter of approximately 100 µm using a liquid film of fluorescent ink. This ink, with a viscosity roughly 100 times that of water, was irradiated with an optical vortex, resulting in prints of exceptional positional accuracy at the micrometer scale.

A research team led by City University of Hong Kong (CityU) has achieved a groundbreaking advancement in nanomaterials by successfully developing a highly efficient electrocatalyst which can enhance the generation of hydrogen significantly through electrochemical water splitting.

Systematic copper doping boosts all-solar utilization in tungstic acid nanocrystals.

Researchers at Kanazawa University report in Cell Reports how alterations in the nuclear pores lead to the degradation of anti-tumor proteins.

Deepak Verma from Chulalongkorn University and his international team of researchers are exploring ways to enhance chitosan using techniques like adding photosensitizers, dendrimers, and chemical modifications. They also surveyed the use of chitosan nanoparticles for medical purposes, notably wound dressings.

A team of researchers from Singapore and the UK, led by project supervisor, Associate Professor Kheng Lim Goh, has developed a portable device for repairing hard-to-see damage in carbon fiber materials. The device has great potential for the aerospace industry, such as to repair the fuselage of commercial aircraft.

succeeded in preparing atactic C1 polymers with a high melting point of up to 130 ℃ by utilizing a hydrogen-bonding interaction among amide-linkages incorporated into the polymer side-chains.

Illuminating the molecular ballet in living cells, Charting the voyage of marine plastics, A glimpse into the origins of life & Earliest human journeys to Asia. Plus Submissions open for Asia Research News 2024. Read all in the latest Editor's Choice.

Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are a way to avoid biopsies by catching free-floating DNA, a large dip in the Earth’s surface under the Indian Ocean, and how people who brush their teeth before bed seem to have healthier hearts.

- A research team led by Dr. Byeong-dae Choi at the Division of Electronics & Information System, DGIST, greatly improved the efficiency of electroluminescent devices by applying silver nanofilms. - This opens up the possibility of developing affordable digital film signage.

Researchers from SANKEN (The Institute of Scientific and Industrial Research), at Osaka University demonstrated a method for drying cellulose nanofiber (CNF) that retains the unique properties of the thickening agent. High transparency, high viscosity, and controllable viscosity were restored with simple stirring after the CNF was dehydrated from an organogel. Our powder had a much smaller volume than freeze-dried CNF, which will facilitate more efficient transport and storage. The method is expected to have a significant impact on food and cosmetics manufacturing.

An international team led by Professor Yan Xu from Osaka Metropolitan University has developed a groundbreaking nanofluidic device, named NANa, capable of stochastically capturing and digitally detecting individual proteins at cellular concentrations. This tool, vital for precision medicine, is designed to handle tiny volumes equivalent to a single cell's contents and can identify single biomolecules even in high-concentration environments. The team plans to conduct further demonstrations using actual cell samples and explore the integration of this tool with AI and biological big data. This research could potentially revolutionize personalized disease prevention and treatment.

Researchers at Kanazawa University report in ACS Nano how ultrathin layers of tin disulfide can be used to accelerate the chemical reduction of carbon dioxide — a finding that is highly relevant for our quest towards a carbon-neutral society.

Researchers from Institute of Industrial Science, The University of Tokyo develop a nanosheet oxide semiconductor for electronic devices

Scientists from Thailand, France and Singapore have conducted groundbreaking research using both tiny cellulose nanofibers (CNF) and long pineapple leaf fibers (PALF) to create stronger materials. They added varying amounts of CNF to epoxy and found that 1% CNF greatly increased impact strength. PALF-epoxy composites showed significant flexibility and strength improvements. Combining CNF and PALF resulted in a remarkable increase in impact strength. The findings could revolutionize stronger material development.

Ultrafast fluorescent imaging technology brings the molecular dynamics of living cells into clear view.

To improve the therapeutic techniques to treat those with brain disorders, researchers have developed microscopic, thermally-drawn microelectronic fiber-based neural probes as a means to manipulate both electrical and chemical signals in the brain. Now, a researcher from Tohoku University’s Frontier Research Institute for Interdisciplinary Sciences has led a group that increased the functionality of these fibers by equipping them with neurochemical sensing aptamers.

Specially coated surfaces help scientists investigate what happens when cell clusters are turned upside down.

A joint research group at Osaka Metropolitan University has succeeded in regulating the flow of single molecules in solution by opening and closing the nanovalve mounted on the nanofluidic device by applying external pressure. The research group fabricated a device with a ribbon-like, thin, soft glass sheet on the top, and at the bottom a hard glass substrate having nanochannels and nanovalve seats. By applying external pressure to the soft glass sheet to open and close the valve, they succeeded in directly manipulating and controlling the flow of individual molecules in solution. They also observed an effect of fluorescence signal amplification when single fluorescent molecules are confined in the tiny nanospace inside the valve. The effect can be ascribed to the nanoconfinement, which suppresses the random motion of the molecules.

Allowing the direct observation of biomolecules in dynamic action, high-speed AFM has opened a new avenue to dynamic structural biology. An enormous amount of successful applications within the last 15 years provide unique insights into essential biological processes at the nanoscale – visualizing, for example, how molecular motors execute their specific functions.