16 Feb 2022
This is a novel study that attempted to construct a pH-sensitive delivery system into T cells and their subsets using carboxy-terminal Phe- and CHex-modified dendrimers with different structures, i.e. PAMAM-CHex-Phe and PAMAM-Phe-CHex. The findings contribute to the development of nanoplatforms for direct delivery to T cells to control the functions of T cells, which play key roles in cancer immunotherapy. This is the first report on direct delivery into T cells using pH-sensitive DDS.
31 Jan 2022
Garden soil houses a variety of bacteria and their natural byproducts — including one that may help halt tumor growth. Lankacidins are molecules that can be isolated from Strepomyces rochei, a common bacterium in soil. In addition to antimicrobial properties, a type of lankacidins, called lankacidin C, can inhibit tumor activity in various cancer cell lines, including leukemia, melanoma, ovarian and breast cancers. Lankacidin C offers a potential foundation on which to design anticancer drugs, but its structure is complicated and difficult to manipulate, according to an international research group. The same group recently identified where antitumor activity is housed on the molecule and has now used that information to simplify lankacidin as a potential starting point to engineer treatments.
08 Dec 2021
A new saliva-based COVID-19 Antigen Rapid Test (ART) technology co-developed by the SingHealth Duke-NUS Academic Medical Centre and the National University of Singapore shows promise in early clinical testing, outperforming existing ARTs and delivering results in minutes, with nearly comparable sensitivity to the gold standard Polymerase Chain Reaction (PCR) test.
02 Nov 2021
Researchers from The University of Tokyo Institute of Industrial Science use optical microscopy to form a picture of what’s really going on inside surfactant onions
01 Oct 2021
Paris, 29 September — UNESCO and the L'Oréal Foundation are unveiling the winners of this year’s International Prize for Women in Science, which honours five eminent women scientists with exceptional careers from the five regions of the world, as it has done annually since 1998.
27 Sep 2021
The missing link isn’t a not-yet-discovered fossil, after all. It’s a tiny, self-replicating globule called a coacervate droplet, developed by two researchers in Japan to represent the evolution of chemistry into biology.
13 Sep 2021
iCeMS scientists and colleagues have designed a molecular code that powers up cancer-fighting immune cells.
17 Mar 2021
Researchers improve their newly established quantum algorithm, bringing it to one-tenth the computational cost of Quantum Phase Estimation, and use it to directly calculate the vertical ionization energies of light atoms and molecules such as CO, O2, CN, F2, H2O, NH3 within 0.1 electron volts of precision.
05 Mar 2021
An international team of researchers has found that A. virginicus extracts appear to be effective against several human diseases, including diabetes and cancer. The results were published on Dec. 31, 2020, in a special issue of Plants, titled “Biological Activities of Plant Extracts.”
03 Mar 2021
Osaka City University finds that the chemical sesaminol, naturally occurring in sesame seeds, protects against Parkinson’s disease by preventing neuronal damage that decreases the production of dopamine. In vitro experiments show sesaminol handle oxidative stress in cells by regulating the production of reactive oxygen species and the movement of antioxidants. In vivo experiments reveal that a diet of sesaminol increases production of dopamine and significantly improve motor functions in mice.
10 Feb 2021
Researchers at The University of Tokyo discover a new law about how the complex network of phase-separated structures grows with time, which may lead to more efficient batteries and industrial catalysts
18 Jan 2021
Researchers at Osaka City University use quantum superposition states and Bayesian inference to create a quantum algorithm, easily executable on quantum computers, that accurately and directly calculates energy differences between the electronic ground and excited spin states of molecular systems in polynomial time.
28 Dec 2020
Investigations of a cellular protein have uncovered a possible link with schizophrenia.
28 Dec 2020
iCeMS scientists have revealed how a transporter protein twists and squeezes compounds out of cells, including chemotherapy drugs from some cancer cells.
23 Dec 2020
A transporter protein that regulates cell membrane cholesterol likely played an important role in vertebrate evolution, according to a review published by iCeMS researchers in the journal FEBS Letters.
19 Nov 2020
A repetitive DNA sequence that causes health risks when it malfunctions can now be watched inside living cells using a synthetic tool
29 Sep 2020
Researchers at Osaka City University produce malic acid, which contains 4 carbon atoms, through artificial photosynthesis by simply adding metal ions like aluminum and iron. This solves a problem with current artificial photosynthesis technology of only producing molecules with 1 carbon atom and paves the way to exploring the use of CO2 as a raw material.
03 Aug 2020
Researchers at Kanazawa University report in ACS Nano a high-speed atomic-force microscopy study of the formation of protein fibrils (amyloids) associated with pathologies in collaborated research with Showa University. Mixing different variants of a single protein and changing the acidity of its environment is shown to result in significant variations in amyloid structure and elongation rates.
19 Aug 2019
DGIST Professor Jaeheung Cho in the Department of Emerging Materials Science secured materials that lead aldehyde deformylation reaction. Confirmed the nucleophilic reactions by biomimetic materials… Expects to bring positive impacts on related research.
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Prof. Muneyuki Matsuo is an Assistant Professor at the Department of Chemistry, School of Science / Program of Mathematical and Life Sciences, Graduate School of Integrated Sciences for Life, Hiroshima University
Carla Portugal is currently an Assistant Researcher at LAQV-Requimte, NOVA.iD.FCT and is experienced in the development, implementation and monitoring of membrane based processes.
Tony Z. Jia is a researcher at Japan’s Earth-Life Science Institute (ELSI), based at the Tokyo Institute of Technology. His research focuses on astrobiology, prebiotic chemistry, and origins of life.
I do research on dysmennorrhoea and gender-based violence. I am a pioneer in registered clinical trials on indigenous and Ayurveda medicines in Sri Lanka. I have approval for a herbal preparation, for COVID patients.
Dr.Ms.Aruna Dhathathreyan is a professor and emeritus scientist at the Advanced Materials Lab, CSIR-Central Leather Research Institute, India.