Medicine & Healthcare

The presence of T cells with low-levels of Bach2 contributes to the worsening and/or prolongation of allergic dermatitis symptoms

The study conducted by Prof. Thai-Yen Ling at National Taiwan University underscores the potential of small extracellular vesicle (sEV) therapy and enhances the precision of acute liver failure treatment through the application of click chemistry.

The Ateneo Laboratory for Intelligent Visual Environments (ALIVE) found a way to identify tooth and sinus structures with an accuracy of 98.2%

Researchers develop innovative phospholipids that improve the functional delivery of mRNA via lipid nanoparticles, paving the way for advanced therapeutic applications.

The current capabilities of large language models already qualify them to advise students on medical ethics

A study shows apixaban lowers clot recurrence in dialysis patients post-thrombectomy, with minor bleeding risks.

Considerable positive results found in mice with skin condition induced by external factors

* "Survivors of SJS/TEN Face a Higher Risk of Cardiovascular Diseases and Death for Years After the Acute Phase" * "Tailored Strategies Needed for Early Detection, Prevention, and Intervention to Reduce Long-Term Cardiovascular Burdens in SJS/TEN Survivors"

Effective treatment of gastric cancer-bacterial infections begins with understanding differing clinical methods

Surviving Antarctica, Probiotics ease anxiety, Ancient mariners, Addressing large urban fires, Smart patch & Dying galaxies. Plus Women experts for International Women’s Day 2025. Read all in the latest Editor's Choice.

A self-assessment questionnaire has been developed to evaluate on-the-job training progress

SingHealth Duke-NUS Global Health Institute and Hanoi Medical University launch a new healthcare hub to drive innovation, education and research

Cerebellar rhythm loss due to climbing fiber regression is a shared pathophysiology of motor deficits across cerebellar ataxias.

Researchers from Osaka University found that plasma cells expressing high levels of the protein integrin β7 and the transcription factor KLF2 tend to leave immune tissues and migrate to the bone marrow. There, they become long-lived plasma cells that help create durable antibody responses, which are key to vaccine effectiveness.

Researchers from Osaka University analyzed the clinical dental records of a large group of patients with hypophosphatasia (a skeletal disease) to identify its common oral symptoms. Their findings, including early tooth loss, poor oral habits, and disordered swallowing, may help early diagnosis of hypophosphatasia, thereby improving patient treatment and quality of life.

Hyperspectral imaging and AI can identify individuals using blood vessels in palms

Concurrent steatotic liver disease (SLD) is prevalent among patients with chronic hepatitis B (CHB); however, the effects of the associated cardiometabolic risk factors on all-cause and cause-specific mortality remain unknown. This study demonstrated that cumulative metabolic burden dose- dependently increased the risks of all-cause, liver-related, and cardiovascular mortality in patients with CHB and SLD. Moreover, new-onset diabetes mellitus, hypertension, and weight gain during the follow-up period further exacerbated these risks. However, patients with SLD had a lower risk of mortality than those without SLD. Thus, routine screening and monitoring of metabolic dysfunctions constitute a key element of daily care for patients with CHB.

Researchers at Tohoku University have found one more reason to quit smoking: the inhalation of first-hand and/or second-hand smoke may lead to placental abruption in pregnant mothers.

Cryo-electron microscopy reveals molecular structure of twin motors that power mycoplasma’s ability to glide

Researchers from the Institute of Industrial Science, The University of Tokyo, have found a surprisingly simple way of understanding social-distancing behavior during an epidemic.

This study questions recent claims about the rapid effectiveness of psychedelic drugs for treating depression. Among all psychedelics, only high-dose psilocybin showed greater effectiveness than the placebo in antidepressant trials and outperformed escitalopram.

Glaucoma is called the “silent thief of sight” as many don’t notice until significant, irreversible vision loss has already occurred. A revolutionary early screening tool using AI may stop this thief dead in its tracks.

Popular milk and dairy products in Egypt show over 25% prevalence of E. coli

Advancement in veterinary regenerative medicine can help domestic and endangered wild cats alike

Verifying the Esophageal Hypervigilance and Anxiety Scale for clinical use

N-Cadherin is found to boost cardiomyocyte regeneration after injury by stabilizing β-Catenin, suggesting a potential new way to improve the function of human failing hearts.

As populations age worldwide, diseases like pulmonary fibrosis are increasingly impacting life expectancy and quality. Duke-NUS researchers have identified that blocking specific proteins in immune cells can significantly reduce or reverse lung scarring. This discovery paves the way for novel treatments that could potentially reverse damage from pulmonary fibrosis.

Researchers from Osaka University found that peristaltic pump flow mechanically breaks supersaturation to induce amyloid formation by hen egg white lysozyme, α-synuclein, amyloid β 1-40, and β2-microglobulin. The high shear stresses induced by peristaltic flow likely reflect those that occur the blood and cerebrospinal fluid, suggesting that this factor could promote amyloidosis.

A bilayer alginate hydrogel system encapsulating polyelectrolyte complex nanoparticles (PCNs) loaded with anti-inflammatory cytokines and angiogenic growth factors, which reducing inflammation, stimulating angiogenesis, and accelerating wound closure in a diabetic murine model.

A multi-institutional research team led by Osaka University found that tricaprin, a natural supplement, improved long-term survival rates in patients with triglyceride deposit cardiomyovasculopathy, a new type of heart disease characterized by impaired triglyceride breakdown in heart and smooth muscle cells. Tricaprin improved clinical symptoms and long-term survival. Studying the effects of tricaprin on patients of different ethnicities would be an ideal next step to gather more evidence in favor of the drug.