Medicine & Healthcare

News

03 Sep 2020
Study by researchers at Duke-NUS Medical School, Duke University and SingHealth finds that dispatch-assisted CPR, training in CPR and use of an Automated External Defibrillator, and a volunteer first responder mobile app, increased the likelihood of laypeople performing CPR during out-of-hospital cardiac arrest, which was associated with increased survival rates.
01 Sep 2020
Researchers at the Smart-Aging Research Center (IDAC) at Tohoku University have developed an innovative training protocol that, utilizing immersive virtual reality (IVR), leads to real physical and cognitive benefits.
28 Aug 2020
Scientists have reviewed reported cases and testing data of COVID-19 and have determined that changes in the testing rate may be masking the true growth rate and extent of the pandemic.
28 Aug 2020
Understanding the skin damage caused by rubbing could lead to better topical skin treatments and help prevent the formation of new routes for viral and bacterial infection.
27 Aug 2020
The older population and those with dementia around the world are facing an unprecedented threat from COVID-19 which threatens them with a higher risk of death when infected. As of 23 August 2020, in Hong Kong, the mortality rate for people aged 60 or above was around 6.27%, which was almost 105 times of those below 60 (0.06%). All deaths from the third wave of COVID-19 in Hong Kong are 60 years old or above. Data from the United Kingdom showed that having dementia was associated with a two-fold increase in the risk of death from COVID-19. In light of this, a dementia team of the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine), initiated an international effort to devise strategies that can reduce the adverse impact which can come from public health interventions and protect them from getting COVID-19.
26 Aug 2020
Duke-NUS, the only graduate-entry medical school in Singapore, has joined the TriNetX global research network to increase clinical trial adoption and to facilitate better collaboration with other global healthcare organizations (HCOs). This latest member for TriNetX in Asia will provide the network with access to de-identified data from more than a million patients.
26 Aug 2020
A group of scientists have detected genetic material from SARS-CoV-2 in untreated wastewater samples collected in April 2020 from two wastewater treatment plants in Louisiana, USA.
24 Aug 2020
Hong Kong has been experiencing hotter summers and more scorcher days in recent years due to climate change and heat island effect. Amid the increasing number of “hot nights”, it is found that consecutive “hot nights” are more detrimental to human health than “very hot days”, although the actual temperature does not reach the level of daytime, according to a collaborative research conducted by the Institute of Future Cities at The Chinese University of Hong Kong (CUHK), as well as researchers from the University of Hong Kong. The research also identified that lack of urban greenery and poor air ventilation in a high-density context are factors that lead to more “hot nights” than “hot days” in some areas. The team suggests that better urban planning and building design are long-term mitigation measures.
Hypothesis for mechanism of action of IL-34 in TNBC
21 Aug 2020
Hokkaido University scientists have shown that Interleukin-34 is a prognostic marker and drug target for Triple Negative Breast Cancer.
21 Aug 2020
Uterine fibroid is a common benign gynaecological disease for women of reproductive age and often leads to heavy menstrual bleeding, pelvic pain and pressure related symptoms. Both surgical and non-surgical treatment options, such as High-Intensity-Focused-Ultrasound (HIFU), are available for patients nowadays. The Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) has developed a modified HIFU treatment protocol for patients with uterine fibroid. The innovative procedure implements a modified energy transmission protocol and oxytocin augmentation which has proved to provide better therapeutic outcomes than other non-surgical treatments. The findings were recently published in the international journal Ultrasound in Medicine & Biology.
20 Aug 2020
A new catalyst design enables unprecedented control over the modification of fatty acid derivatives that opens the door to creating useful substances in a green and efficient manner.
18 Aug 2020
Under the “Saving the Lives of Healthcare Workers” project in the Philippines, ASSIST and Project HOPE will distribute kits of personal protective equipment (PPE) to select hospitals and health facilities in COVID-19 hotspots in the Philippines.
City University of Hong Kong, CityU, CityUResearch
18 Aug 2020
Malignant glioma is the most common type of primary brain cancer. But lack of early diagnosis, among many other factors, has made it difficult to be treated. Recently, a team of cross-disciplinary scientists from City University of Hong Kong (CityU) has discovered new biomarkers in blood serum, which can be quantitatively detected by the label-free biosensors developed by the team, for the early detection of glioma progression. The findings enable a non-invasive liquid biopsy of glioma to be conducted, making it a promising diagnostic tool in the future.
18 Aug 2020
Nanoprodrugs have immense potential for cancer treatment, more so than conventional drug delivery systems. Researchers have, for the first time, developed a comprehensive study on the dynamics of the SN-38 nanoprodrug.
17 Aug 2020
The human brain efficiently executes highly sophisticated tasks, such as image and speech recognition, with an exceptionally lower energy budget than today's computers can. The development of energy-efficient and tunable artificial neurons capable of emulating brain-inspired processes has, therefore, been a major research goal for decades.
17 Aug 2020
Duke-NUS spinout, PairX, led by US and Singapore scientists and investors, to advance immunotherapy biotech exclusively licensed from Duke-NUS.
12 Aug 2020
Researchers in China have taken the first step towards a new way of treating gastric wounds by using a microrobot combined with the new concept of “in situ in vivo bioprinting” to carry out tissue repair inside the body.
Methods used to recover MHV in this study
12 Aug 2020
A group of researchers have demonstrated that, from seven methods commonly used to test for viruses in untreated wastewater, an adsorption-extraction technique can most efficiently detect SARS-CoV-2. This gives us another tool to detect the presence and spread of the COVID-19 pandemic
11 Aug 2020
A large cohort study conducted by the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine), in collaboration with investigators from the University of Sydney, Australia, has discovered that shortened DNA telomere length is a useful biomarker linked to a higher risk of developing cardiovascular disease in patients with type 2 diabetes. The Endocrinology and Diabetes team of CU Medicine evaluated this biomarker in over 5,300 type 2 diabetes patients during a 13-year follow-up period. Patients with cardiovascular disease at baseline or during follow-up had shorter tail-ends of DNA strands, expressed as relative Leukocyte Telomere Length (rLTL), than those who never had cardiovascular disease. For each unit relative decrease in rLTL, the risk of cardiovascular disease increased by 25%. These results have been published in the leading diabetes journal, Diabetes Care.
10 Aug 2020
The Faculty of Education and Human Development at The Education University of Hong Kong (EdUHK) launched its new Bioanalytical Laboratory for Educational Sciences (BLESS) with paid services in July 2020. This is the first bioanalytical lab to focus on education research in Hong Kong.
Scientists who contributed to this research
07 Aug 2020
Scientists have unveiled a correlation between high blood lead levels in children and methylation of genes involved in haem synthesis and carcinogenesis, indicating a previously unknown mechanism for lead poisoning.
06 Aug 2020
Researchers from the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) have recently conducted a study to investigate the impact of liver injury on clinical outcomes in COVID-19 patients. Data from over 1,000 COVID-19 patients in Hong Kong was analysed and liver injury was found in around 20% of the patients. The estimated risk of COVID-19 patients with liver injury experiencing adverse clinical outcomes such as intensive care unit (ICU) admission, use of invasive mechanical ventilation or death was almost eight times of other patients. It is suggested that liver function monitoring is important regarding its association with adverse clinical outcomes in COVID-19 patients. These findings have been published recently in the world-renowned medical journal Gut. In view of the high prevalence of various chronic liver diseases in the Asia-Pacific region, CU Medicine’s researchers led a group of experts from Mainland China, Japan, Singapore and Australia to issue a position statement on the management of COVID-19 patients with liver derangement. The statement has been published recently in another international medical journal The Lancet Gastroenterology & Hepatology.
05 Aug 2020
Community rehabilitation; psychological impact of caregiving emerges as top interests
05 Aug 2020
The somatic nuclear protein kinase VRK-1 increases the worm’s lifespan through AMPK activation, and this mechanism can be applied to promoting human longevity, the study reveals.
04 Aug 2020
Recurrent miscarriages (RM) cause frustration and trauma to couples who want to have a child. However, not all couples can find out about the underlying reasons because of medical constraints. The Department of Obstetrics and Gynaecology (O&G) of the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) has successfully developed a new genome sequencing test called ChromoSeq to identify the genetic defects for married couples, who suffered from RM. When compared with the conventional karyotyping analysis, ChromoSeq offers greater accuracy in detecting potential genetic abnormalities associated with RM in affected couples. The team conducted a study on the innovation and the findings were recently published in the international journal American Journal of Human Genetics.
04 Aug 2020
Dr. Timothy Liong Tipoe, a 2019 graduate of the MBChB programme in the Global Physician-Leadership Stream of The Chinese University of Hong Kong (CUHK), has been awarded the Esther Yewpick Lee Millennium Scholarship to pursue a DPhil in Clinical Medicine at the University of Oxford, starting from October this year. Timothy has always excelled in academics, as demonstrated by his 11A*s in the 2012 General Certificate of Secondary Education (GCSE) and a perfect score of 45 in the 2014 International Baccalaureate (IB) Diploma.
04 Aug 2020
Prognosis describes how serious a patient’s cancer is and his or her chance of survival. A genetic biomarker is a clinically useful tool to help estimate the state of the disease. A study, conducted by the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine), has identified a gene called GPR18 which can be a biomarker to help form the prognosis for a patient in nine cancer types. The research team has also provided new insights into B-cells for a cancer patient’s prognosis. The findings were recently published in the international scientific journal Communications Biology - Nature.
03 Aug 2020
Researchers at Kanazawa University report in ACS Nano a high-speed atomic-force microscopy study of the formation of protein fibrils (amyloids) associated with pathologies in collaborated research with Showa University. Mixing different variants of a single protein and changing the acidity of its environment is shown to result in significant variations in amyloid structure and elongation rates.
30 Jul 2020
A study conducted over the past 18 years has found differences between lead exposure effects in young Japanese boys versus girls.
30 Jul 2020
In a May 2020 Webinar, Dr. Sam Shah, Global Digital Health Advisor and Consultant with UK’s National Health System (NHS) discusses how the COVID-19 pandemic is reshaping healthcare with technology, specifically the response of UK’s NHS.

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