Press releases

Malignant glioma is the most common type of primary brain cancer. But lack of early diagnosis, among many other factors, has made it difficult to be treated. Recently, a team of cross-disciplinary scientists from City University of Hong Kong (CityU) has discovered new biomarkers in blood serum, which can be quantitatively detected by the label-free biosensors developed by the team, for the early detection of glioma progression. The findings enable a non-invasive liquid biopsy of glioma to be conducted, making it a promising diagnostic tool in the future.

Nanoprodrugs have immense potential for cancer treatment, more so than conventional drug delivery systems. Researchers have, for the first time, developed a comprehensive study on the dynamics of the SN-38 nanoprodrug.

The human brain efficiently executes highly sophisticated tasks, such as image and speech recognition, with an exceptionally lower energy budget than today's computers can. The development of energy-efficient and tunable artificial neurons capable of emulating brain-inspired processes has, therefore, been a major research goal for decades.

Duke-NUS spinout, PairX, led by US and Singapore scientists and investors, to advance immunotherapy biotech exclusively licensed from Duke-NUS.

Researchers in Kanazawa University has recently reported their study in Nano Letters regarding a high-speed atomic force microscopy study on a biological event that happens during flu virus enters infects its host cell. The real-time visualization of influenza A hemagglutinin (HA) has enhanced the understanding of fusogenic transition of HA and its interactions with host endosomes.

In catalytic reactions with organocatalysts, it is difficult to control radical reactions. We designed a thiazolium-type N-heterocyclic carbene catalyst having an N-neopentyl group. This catalyst was found to actively control radical reactions and enabled production of more than 35 species of bulky dialkyl ketones from an aliphatic aldehyde and an aliphatic carboxylic acid derivative through a radical relay mechanism. This catalyst is expected to open the way for acceleration of drug discovery research.

Researchers in China have taken the first step towards a new way of treating gastric wounds by using a microrobot combined with the new concept of “in situ in vivo bioprinting” to carry out tissue repair inside the body.

A group of researchers have demonstrated that, from seven methods commonly used to test for viruses in untreated wastewater, an adsorption-extraction technique can most efficiently detect SARS-CoV-2. This gives us another tool to detect the presence and spread of the COVID-19 pandemic

Forty-five of the world’s most influential leaders and innovators participated in EmTech Asia. They discussed how emerging technologies will influence industries related to artificial intelligence, robotics, sustainability, healthcare, immersive media, and more.

In the era of smart cities and amid the global outbreak of Covid-19, connecting through the internet is getting more important than ever. Researchers have been working day and night on advancing the optical data transmission network to address the demand for faster transmission speed. An international research team has developed a new technology that is equipped with a special chip made by a scientist from City University of Hong Kong (CityU). The team broke the spectral efficiency world record for optical data transmission with a single integrated photonic chip. This allows the transmission speed as fast as downloading 1,000 high-definition movies in less than a second!

Scientists from the Daegu Gyeongbuk Institute of Science and Technology, Republic of Korea, discover a new way to diagnose Alzheimer’s disease by analyzing the levels of specific proteins in nasal discharge. This simple and inexpensive method could help in timely diagnosis of Alzheimer’s disease, in order to start treatment as soon as possible, thus delaying disease progression.

A large cohort study conducted by the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine), in collaboration with investigators from the University of Sydney, Australia, has discovered that shortened DNA telomere length is a useful biomarker linked to a higher risk of developing cardiovascular disease in patients with type 2 diabetes. The Endocrinology and Diabetes team of CU Medicine evaluated this biomarker in over 5,300 type 2 diabetes patients during a 13-year follow-up period. Patients with cardiovascular disease at baseline or during follow-up had shorter tail-ends of DNA strands, expressed as relative Leukocyte Telomere Length (rLTL), than those who never had cardiovascular disease. For each unit relative decrease in rLTL, the risk of cardiovascular disease increased by 25%. These results have been published in the leading diabetes journal, Diabetes Care.

Researchers have found electrons that behave as if they have no mass, called Dirac electrons, in a compound used in rewritable discs, such as CDs and DVDs. The discovery of “massless” electrons in this phase-change material could lead to faster electronic devices.

The Faculty of Education and Human Development at The Education University of Hong Kong (EdUHK) launched its new Bioanalytical Laboratory for Educational Sciences (BLESS) with paid services in July 2020. This is the first bioanalytical lab to focus on education research in Hong Kong.

A group of researchers from three Japanese universities has discovered why the western subarctic Pacific Ocean, which accounts for only 6 percent of the world’s oceans, produces an estimated 26 percent of the world’s marine resources.

Scientists have unveiled a correlation between high blood lead levels in children and methylation of genes involved in haem synthesis and carcinogenesis, indicating a previously unknown mechanism for lead poisoning.

Understanding the microscopic origin of different physical properties of solids is of fundamental importance for condensed-matter physics and for materials applications. Yet, there is still a lot of unknowns in amorphous materials due to their disordered atomic structure. Recently, with the state-of-the-art neutron scattering instrumentation and molecular dynamic simulations, an international research team, led by physicists from City University of Hong Kong (CityU), has demonstrated the existence of high-frequency transverse phonons in metallic glass for the first time. Their findings also suggest that the atomic structure correlates with its atomic dynamics, providing new insight for understanding the atomic structure-dynamics relationship in disordered materials.

Researchers from the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) have recently conducted a study to investigate the impact of liver injury on clinical outcomes in COVID-19 patients. Data from over 1,000 COVID-19 patients in Hong Kong was analysed and liver injury was found in around 20% of the patients. The estimated risk of COVID-19 patients with liver injury experiencing adverse clinical outcomes such as intensive care unit (ICU) admission, use of invasive mechanical ventilation or death was almost eight times of other patients. It is suggested that liver function monitoring is important regarding its association with adverse clinical outcomes in COVID-19 patients. These findings have been published recently in the world-renowned medical journal Gut. In view of the high prevalence of various chronic liver diseases in the Asia-Pacific region, CU Medicine’s researchers led a group of experts from Mainland China, Japan, Singapore and Australia to issue a position statement on the management of COVID-19 patients with liver derangement. The statement has been published recently in another international medical journal The Lancet Gastroenterology & Hepatology.

Research at Kanazawa University as reported in Scientific Reports demonstrates atomic force microscopy imaging that gets around the challenges of exciting very small cantilevers at their high megahertz resonance frequencies. The approach accomadates wide frequency bandwiths, and is applicable for photosensitive materials in a wide range of liquids.

Community rehabilitation; psychological impact of caregiving emerges as top interests

The somatic nuclear protein kinase VRK-1 increases the worm’s lifespan through AMPK activation, and this mechanism can be applied to promoting human longevity, the study reveals.

Recurrent miscarriages (RM) cause frustration and trauma to couples who want to have a child. However, not all couples can find out about the underlying reasons because of medical constraints. The Department of Obstetrics and Gynaecology (O&G) of the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) has successfully developed a new genome sequencing test called ChromoSeq to identify the genetic defects for married couples, who suffered from RM. When compared with the conventional karyotyping analysis, ChromoSeq offers greater accuracy in detecting potential genetic abnormalities associated with RM in affected couples. The team conducted a study on the innovation and the findings were recently published in the international journal American Journal of Human Genetics.

The research team directed by H. Shimomoto and E. Ihara in Ehime University synthesized pH-responsive dendronized polymers by C1 polymerization of dendron-containing diazoacetates, and demonstrated a unique pH-responsive behavior of the resulting polymers. These achievements will contribute to progress in the field of polymer chemistry and will allow us to develop new types of smart soft materials.

A research team from The Chinese University of Hong Kong (CUHK) and the University of Warwick has reached a crucial milestone towards developing single-pixel terahertz radiation (T-ray) imaging technology. Their single-pixel T-ray camera reached 100 times faster acquisition than the previous state-of-the-art without adding any significant costs to the entire system or sacrificing the sub-picosecond temporal resolution needed for the most sought-after applications, potentially opening the opportunity for them to be used in non-invasive security and medical screening. The breakthrough has been published in the journal Nature Communications.

Dr. Timothy Liong Tipoe, a 2019 graduate of the MBChB programme in the Global Physician-Leadership Stream of The Chinese University of Hong Kong (CUHK), has been awarded the Esther Yewpick Lee Millennium Scholarship to pursue a DPhil in Clinical Medicine at the University of Oxford, starting from October this year. Timothy has always excelled in academics, as demonstrated by his 11A*s in the 2012 General Certificate of Secondary Education (GCSE) and a perfect score of 45 in the 2014 International Baccalaureate (IB) Diploma.

The ever-increasing growth in data traffic requires more powerful transmission networks. To respond to such demand, a group of researchers led by Prof. Xiankai Sun and Prof. Hon Ki Tsang in the Department of Electronic Engineering, The Chinese University of Hong Kong (CUHK) has recently revealed a way to use light to convey large rates of data in advanced optical chips. Their findings and demonstrations shed new light on increasing the data capacity with low insertion loss and crosstalk. These research results have been recently published in the prestigious scientific journal Nature Communications.

Prognosis describes how serious a patient’s cancer is and his or her chance of survival. A genetic biomarker is a clinically useful tool to help estimate the state of the disease. A study, conducted by the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine), has identified a gene called GPR18 which can be a biomarker to help form the prognosis for a patient in nine cancer types. The research team has also provided new insights into B-cells for a cancer patient’s prognosis. The findings were recently published in the international scientific journal Communications Biology - Nature.

Researchers at Kanazawa University report in ACS Nano a high-speed atomic-force microscopy study of the formation of protein fibrils (amyloids) associated with pathologies in collaborated research with Showa University. Mixing different variants of a single protein and changing the acidity of its environment is shown to result in significant variations in amyloid structure and elongation rates.

An artificial intelligence approach extracts how an aluminum alloy’s contents and manufacturing process are related to specific mechanical properties.

Researchers have solved a major problem for optical wireless communications - the process by which light carries information between cell phones and other devices. Light-emitting diodes (LEDs) pulse their light in a coded message that recipient devices can understand.