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Cells have surface receptors that couple to proteins and other molecules to initiate or inhibit certain behaviors. Researchers have found that one of these receptors helps set developing cells on the path to becoming neurons much earlier than previously thought.

Researchers from National Taiwan University (NTU) and National Taiwan University Hospital (NTUH) have identified a promising way to reinvigorate the body's cancer-fighting immune cells by rewiring their metabolism, revealing a potential new strategy for cancer immunotherapy.

Researchers from The University of Osaka found that using a sequence analysis approach that incorporates awareness of insertions and deletions in extramembrane domains enabled accurate reconstruction of ancestral rhodopsins that folded correctly and functioned as predicted when expressed in E. coli. The researchers’ ConsistASR analytical pipeline could be used to engineer other ancestral proteins in the future.

Researchers demonstrate a systematic screening method that can help find promising catalyst candidates without the tedious trial-and-error of every single possible combination.

Philippine Studies: Historical and Ethnographic Viewpoints has just published its latest issue, Workers’ Struggles.

Researchers at the University of Osaka have developed a quantum mechanical model for concentrated organic radical solutions considering stochastic collisions between molecules. The first-order contribution to intermolecular interactions is averaged to zero by collisional fluctuations, but the second-order term survives and enhances the magnetic susceptibility. These results explain experimental observations of an anomalous increase in the magnetic susceptibility at the solid-to-fluid transition that cannot be predicted by conventional theories.

A research group led by Dr. Keiko Ueno, Assistant Professor at the Innovative Clinical Research Center, Kanazawa University, has revealed the status of collaboration between fire-based emergency medical service (EMS) agencies *1) and community-based long-term care *2), welfare *3), and health organizations *4) in Japan. The study identified six key practical measures essential for building a collaborative model that sustains long-term coordination between medical care and social support needs.

Discovering new catalysts to power hydrogen production often involves a time-consuming trial-and-error process. Not only that, but materials scientists often have to comb through troves of scientific data and experimental data. Yet these days may be over thanks to a new AI-powered platform that enables researchers to identify new catalysts for methane pyrolysis— a promising technology for producing hydrogen with lower carbon emissions.

Cryo-electron transmission microscopy helps scientists observe biological specimens in a state that closely resembles their natural environment, especially those dispersed in water. But applying the technique outside of aqueous systems has proved relatively difficult. However, researchers at Tohoku University have created a new technique that enabled cryo-TEM to be applied to frozen methanol, opening a new avenue for studying materials in a wider variety of natural states.

Mechanoluminescent materials, which convert mechanical energy into light, are great for self-powered sensors. However, they have traditionally been made using rare earth materials or complex material compositions, making them relatively expensive to manufacture. Now, a research team has developed a zinc oxide material that not only possesses highly sensitive mechanoluminescence but is made from cheap, earth-abundant materials.

Single-Step Plasma Process Produces Optoelectronic Synapse for 3D Stackable Neuromorphic Vision

Astronomical observations provide new insights into how galaxies formed and grew during the Universe's first billion years

Researchers at Kanazawa University identified dopamine-driven neural mechanisms of motivation in a mouse model of behavioral addiction, offering insights into treatment.

Scientists found a gene that helps rice flower earlier, in the cooler morning hours, allowing it to avoid heat stress and protect grain formation and yields in warm regions.

South-facing green walls help lower temperatures in indoor and outdoor environments

Researchers at Kanazawa University have identified a previously unrecognized mechanism by which structural changes in the cerebellum influence social behavior. The study demonstrates that disruption of specialized extracellular structures surrounding cerebellar neurons alters neuronal activity across brain circuits involved in social behavior. The findings provide new insight into the neural mechanisms associated with autism spectrum disorder (ASD).

A research group led by Professor Katsuhiro Ichikawa (Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University) and Professor Kaoru Tada (Faculty of Health Sciences / Department of Orthopaedic Surgery, Kanazawa University Hospital) has successfully developed an ultra-high-resolution X-ray computed tomography (CT) system dedicated to extremities, achieving approximately five times higher spatial resolution than conventional X-ray CT systems (voxel size: 0.08–0.10 mm).

Based on their 18-year long cohort study, researchers at Tohoku University have found which depressive symptoms have the most impact on the “healthspan” (remaining years of healthy living) of older adults, and how this differs for men compared to women.

High-pressure experiments show that majorite can store moderate amounts of ferric iron.

Researchers at National Taiwan University refined a pseudo-germ-free mouse model to make gut microbiome studies safer for mice and more reliable. Using this model, they found that antibiotic-driven changes in gut microbes suppressed pancreatic tumor growth and enhanced the effect of gemcitabine chemotherapy.

Researchers investigated the prevalence of an emerging foodborne disease-causing bacterium in wild raccoons and environmental water. They found genetic similarities between the strains found in both, suggesting possible transmission between wildlife and water. Genomic analyses of samples taken from the raccoons showed that many strains found in the animals carried virulence genes associated with diarrhea outbreaks in humans.

An exciting new strategy involving a specially designed iron-based catalyst can speed up the reaction that powers next-gen zinc-air batteries. This means cleaner, more efficient energy for everyone.

NSF VLA and ALMA observations detect enormous cold molecular gas reserves in a distant galaxy seen 13 billion years ago, a study involving Hiroshima University reports.

Researchers at Kanazawa University discover how the microenvironment fuels double-negative castration-resistant prostate cancer (DNPC) and demonstrate the therapeutic potential of pan-KRAS inhibitors.

An international research collaboration, including OMU, IJS, NIST and AUT, has unveiled a robust metallic state in the molecular material ytterbium cesium fulleride (Yb₂CsC₆₀) that directly tests conventional theories of electron behavior. Normally, strong interactions between electrons are expected to suppress their movement and turn materials into insulators through a process called a Mott transition. However, Yb₂CsC₆₀ represents a case where metallicity survived, suggesting that the material’s electrons were continuing to move collectively, stabilized by a different mechanism. The discovery is of relevance to future research in fields such as superconductivity, quantum matter, and next-generation electronic technologies.

Researchers from The University of Osaka developed a computational imaging method that combines coded-aperture optics with diffusion-model-based artificial intelligence to recover both depth and sharp color images from a single photograph. The approach improves robustness across imaging conditions while reducing reconstruction errors commonly seen in existing methods.

A nationwide study tracking Japanese adults before, during, and after the COVID-19 pandemic found that health-related quality of life steadily declined over seven years and did not rebound after the public health emergency ended. Researchers say the decline may reflect the cumulative impact of pandemic-related changes in physical activity, mental well-being, and social interaction among working-age adults across Japan.

Self-assembled nanostructures in the electrolyte control ion flow… achieving world-record performance in both cycle life and capacity simultaneously

Researchers innovated artificial photosynthesis technology by optimizing the electrolyzer part of the system. This tweak enables the continuous production of solar fuel, even with fluctuations in sunlight intensity.

Physician-scientists at Kanazawa University have demonstrated, for the first time worldwide, the clinical efficacy of chemoimmunotherapy in patients with ultra-rare urachal cancer. Furthermore, their reverse translational research elucidated the mechanism by which the addition of immunotherapy enhances the efficacy of chemotherapy.