Japan
News
12 Aug 2020
Hokkaido University
A group of researchers have demonstrated that, from seven methods commonly used to test for viruses in untreated wastewater, an adsorption-extraction technique can most efficiently detect SARS-CoV-2. This gives us another tool to detect the presence and spread of the COVID-19 pandemic
07 Aug 2020
Hokkaido University
A group of researchers from three Japanese universities has discovered why the western subarctic Pacific Ocean, which accounts for only 6 percent of the world’s oceans, produces an estimated 26 percent of the world’s marine resources.
07 Aug 2020
Hokkaido University
Scientists have unveiled a correlation between high blood lead levels in children and methylation of genes involved in haem synthesis and carcinogenesis, indicating a previously unknown mechanism for lead poisoning.
05 Aug 2020
Kanazawa University
Research at Kanazawa University as reported in Scientific Reports demonstrates atomic force microscopy imaging that gets around the challenges of exciting very small cantilevers at their high megahertz resonance frequencies. The approach accomadates wide frequency bandwiths, and is applicable for photosensitive materials in a wide range of liquids.
03 Aug 2020
Kanazawa University
Researchers at Kanazawa University report in ACS Nano a high-speed atomic-force microscopy study of the formation of protein fibrils (amyloids) associated with pathologies in collaborated research with Showa University. Mixing different variants of a single protein and changing the acidity of its environment is shown to result in significant variations in amyloid structure and elongation rates.
27 Jul 2020
Hokkaido University
Hokkaido University researchers have found a soft and wet material that can memorize, retrieve, and forget information, much like the human brain. They report their findings in the journal Proceedings of the National Academy of Sciences (PNAS).
13 Jul 2020
Kanazawa University
A hemispherical vanadium oxide cluster has a cavity that can accommodate a bromine molecule. It was found that a bromine molecule trapped in the cavity was polarized and that an alkane molecule like pentane, butane and propane could be brominated with the bromine molecule in the cavity with a selectivity differing from ordinary bromination. The present findings are expected to be useful for polarization of small molecules and design of highly functional catalysts.
10 Jul 2020
Osaka City University
Scientists demonstrate that the information about host bacteria–bacteriophage (phage) associations derived from world’s first metagenome analysis is useful for the development of phage therapies against intestinal pathobionts.
06 Jul 2020
Kanazawa University
Researchers at Kanazawa University report in Biomaterials a high-speed atomic-force microscopy study of protein filaments in the nuclear pore complex. The visualization in real-time of the filaments’ dynamics is an important step in our understanding of molecular transport mechanisms between a cell nucleus and its surrounding medium.
03 Jul 2020
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
A method that involves infecting liver cells with mosquito-bred parasites could improve the study of malaria in India.
30 Jun 2020
Hiroshima University
Hiroshima University scientists will work on a low-cost sex selection system for bovines using their new technology to help grow dairy herds and boost the incomes of India’s smallholder farmers.
20 Jun 2020
Kanazawa University
Researchers at Kanazawa University report in the Biophysical Journal that the process of cell removal from an epithelial layer follows from an inherent mechanical instability. Moreover, the forces generated by an extruding cell can drive the extrusion of other cells in a particular direction.
09 Jun 2020
Nagoya University
A transparent container made by Nagoya University researchers allows easy and quick grafting of very young plants, with benefits for agriculture and plant research.
04 Jun 2020
International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba
Researchers from University of Tsukuba and the University of Tokyo identify neurons responsible for memory consolidation during REM sleep
03 Jun 2020
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
A highly accurate machine learning tool could help doctors tailor individualized treatments for people with glioma brain tumours.

29 May 2020
Hiroshima University
With increasing unemployment, economists are devising and proposing economic measures that could help ensure a sustainable increase in consumer spending and circumvent a long-term economic recession. However, whether the proposed economic measures are going to provide a long-term solution to these problems remains a concern.
28 May 2020
Kanazawa University
The generation of alkyl radicals was achieved by direct visible-light excitation of the organoborate complex, which was designed and synthesized from “boracene,” which has a boron atom in the tetracene-like skeleton. The alkyl radicals thus obtained could be used as a carbon source for chemical reactions, enabling the synthesis of complicated/bulky organic compounds. The present study offers a new protocol for organic synthesis, which is expected to accelerate e.g. drug discovery.
27 May 2020
Nagoya University
Scientists could gain insight into atypical sex development in vertebrates, including humans, by studying how nutrition affects sex changes in fish larvae.
27 May 2020
Nagoya University
Scientists are unraveling the properties of electricity-conducting plastics so they can be used in future energy-harvesting devices.
22 May 2020
The Chinese University of Hong Kong (CUHK)
Researchers from the School of Life Sciences at The Chinese University of Hong Kong (CUHK) and Japanese research teams have constructed a high-resolution chromosome-scale full genome sequence assembly of an American Shorthair domestic cat (AnAms1.0). By incorporating data from multiple advanced genomic technologies, this genome assembly has a much improved quality over the currently available reference. This research will drive forward precision veterinary medicine to provide the most suitable treatments based on individual differences predicted from genomic information.
18 May 2020
Kanazawa University
Research at Kanazawa University, Theragen Etex Bio Institute and Seoul National University as reported in Nature Communications points towards pathways for the metastasis and malignant transitions that result from changes in the protein p53. The results suggest that the cooperative development of mutations in the proteins helps tumours spread and metastasis.
15 May 2020
Osaka City University
The group clarified for the first time whether formate dehydrogenase reduces carbon dioxide, biocarbonate ion, or carbonate ion to formic acid.
Points to a catalyst in developing and designing an artificial photosynthesis system that efficiently converts carbon dioxide into organic molecules.
13 May 2020
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
Hydrogen fuel cells made with coordination polymer glass membranes could produce as much energy as their liquid-based counterparts while adding strength and flexibility.
12 May 2020
Kanazawa University
In a recent study published in Molecular Cell, researchers at Kanazawa University report the role of cellular structures called PML bodies in regulating gene function
21 Apr 2020
Tohoku University
It is no secret that genetic factors play a role in determining whether children have neurodevelopmental disorders. Maternal exposure to drugs and viral or bacterial illnesses can be detrimental too.
07 Apr 2020
Kanazawa University
Researchers at Kanazawa University and Tsukuba University report in Nanoscale that the physical properties of extracellular bacterial membrane vesicles are significantly diverse. The properties for a single type of bacterium as well as for different types are found to be highly heterogeneous.
06 Apr 2020
Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU)
Two Kavli IPMU string theorists and a condensed-matter theorist have found a quantum mechanical anomaly in the duality between the electric field and the magnetic field, which could play a role in removing an inconsistency in string theory.
30 Mar 2020
Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU)
Neon inside a certain star core can eat so many electrons, it causes the star to collapse into a neutron star and produce a supernova.
27 Mar 2020
Hokkaido University
The remaining “bound water” on cotton surfaces cross-link single fibers of cotton, causing hardening after natural drying, according to a new study conducted by Kao Corporation and Hokkaido University. This provides new insight into unique water behaviors on material surfaces and helps us develop better cleaning technologies.
27 Mar 2020
National Astronomical Observatory of Japan (NAOJ)
Astronomers obtained the first resolved image of disturbed gaseous clouds in a galaxy 11 billion light-years away by using ALMA.
Researchers
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Giants in history
Japanese biochemist Akira Endo (1933 – 2024) discovered the first statin, called mevastatin, which lowered cholesterol levels in the blood by inhibiting a key enzyme in the cholesterol biosynthesis pathway. His work laid the foundation for the development of statins to help patients lower their blood cholesterol levels and reduce their risk of heart disease or stroke.
Ruby Sakae Hirose (1904 – 1960) was a Japanese-American scientist whose research contributed significantly to our understanding of blood clotting, allergies and cancer.
Haisako Koyama (1916 – 1997) was a Japanese solar observer whose dedication to recording sunspots – cooler parts of the sun’s surface that appear dark – produced a sunspot record of historic importance.
Michiaki Takahashi (17 February 1928 – 16 December 2013) was a Japanese virologist who developed the first chickenpox vaccine.
Toshiko Yuasa (11 December 1909 – 1 February 1980) was the first Japanese female physicist whose research on radioactivity shed light on beta decay – the process in which an atom emits a beta particle (electron) and turns into a different element.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Reiji Okazaki (8 October 1930 – 1 August 1975) and Tsuneko (7 June 1933) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.
In 1915, Koichi Ichikawa along with pathologist Katsusaburo Yamagiwa became the first to prove that chronic exposure to chemicals can cause cancer.
In 1915, pathologist Katsusaburo Yamagiwa and his research assistant Koichi Ichikawa became the first to prove that chronic exposure to chemicals can cause cancer.
Ogino Ginko (3 March 1851 – 23 June 1913) was the first registered female doctor to practise modern medicine in Japan.
Michiyo Tsujimura (17 September 1888 – 1 June 1969) was a Japanese agricultural scientist and biochemist recognized for her research of green tea components.
Hitoshi Kihara (1893 – 1986) was one of the most famous Japanese geneticists of the 20th century. One of his most significant contributions was identifying sex chromosomes (X and Y) in flowering plants.
Kono Yasui (16 February 1880 – 24 March 1971) was a Japanese botanist who researched the genetics of poppies, corn and spiderworts and surveyed the plants that had been affected by the nuclear fallout after the atomic bombings of Hiroshima and Nagasaki.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Kikunae Ikeda (8 October 1864 – 3 May 1936) was a Japanese chemist who discovered the fifth basic taste, umami.
Osamu Shimomura (27 August 1928 – 19 October 2018) was a Japanese organic chemist and marine biologist who dedicated his career to understanding how organisms emitted light.
Motoo Kimura (13 November 1924 – 13 November 1994) was a Japanese theoretical population geneticist who is best remembered for developing the neutral theory of molecular evolution.
Chika Kuroda (24 March 1884 – 8 November 1968) was a Japanese chemist whose research focussed on the structures of natural pigments.
The field of solid-state ionics originated in Europe, but Takehiko Takahashi of Nagoya University in Japan was the first to coin the term ‘solid ionics’ in 1967. ‘Solid-state ionics’ first appeared in 1971 in another of his papers, and was likely a play on ‘solid-state electronics’, another rapidly growing field at the time.
The techniques that make industrial pearl culturing possible were developed over a century ago at the Misaki Marine Biological Station in Japan. The station’s first director, Professor Kakichi Mitsukuri, emphasized to Kokichi Mikimoto in 1890 that stimulating pearl sac formation was important for pearl growth, and they went on to successfully develop methods for culturing pearls.
Japanese physicist Ukichiro Nakaya (1900-1962) made the world’s first artificial snowflakes. He started his research on snow crystals in the early 1930s at Hokkaido University, where there is an unlimited supply of natural snow in winter. By taking over 3,000 photographs, he established a classification of natural snow crystals and described their relationship with weather conditions.
Minoru Shirota (April 23, 1899 – March 10, 1982) was a Japanese microbiologist who invented the popular fermented drink Yakult.
Japanese chemist Kenichi Fukui (4 October 1918 – 9 January 1998) was the first Asian scientist to be awarded the Nobel Prize in Chemistry. Together with Roald Hoffman, he received this honour in 1981 for his independent research into the mechanisms of chemical reactions.
Shinichiro Tomonaga (31 March 1906 – 8 July 1979), together with Richard Feynman and Julian Schwinger, was awarded the Nobel Prize in Physics in 1965, for their contributions to advance the field of quantum electrodynamics. Tomonaga was also a strong proponent of peace, who actively campaigned against the proliferation of nuclear weapons and promoted the peaceful use of nuclear energy.
Hideki Yukawa (23 January 1907 – 8 September 1981) was awarded the Nobel Prize in Physics in 1949 for predicting the existence of the pi meson subatomic particle. Japan’s first Nobel laureate, Yakawa also expressed his support for nuclear disarmament by signing the Russell–Einstein Manifesto in 1955.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
Tsuneko (7 June 1933) and Reiji Okazaki (8 October 1930 – 1 August 1975) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.
A Japanese surgeon, Tetsuzo Akutsu (20 August 1922 – 9 August 2007) built the first artificial heart capable of keeping an animal alive.
Japanese geochemist Katsuko Saruhashi developed the first method and tools for measuring carbon dioxide in seawater



























































