09 Jun 2021
Publication bias, or the tendency of researchers and journals to not publish uninteresting findings, plagues much of the natural sciences and especially biomedical research. Hiroshima University researchers have developed a meta-analytic technique exploiting publicly available transcriptome databases that avoids the problem—and in so doing, discovered four genes previously unknown to be associated with responding to low-oxygen stress.
31 May 2021
High-resolution genome structural analyses combined with large-scale simulations show the arrangements of the genome’s spool-like structures affecting gene expression.
13 May 2021
A simple tool allows researchers to track how different subpopulations of the Plasmodium knowlesi parasite are changing over time.
13 Apr 2021
The O. swinhoana frog species is the first vertebrate known to retain descendant genes that now determine sex in mammals, birds, and fishes inherited from a common ancestor.
07 Apr 2021
New national body established to further research insights, improve patient outcomes and create new economic opportunities for the biomedical technology industry.
26 Mar 2021
An ‘eat-me’ signal displayed on cell surfaces requires activation of a lipid-scrambling protein by a nuclear protein fragment.
24 Feb 2021
Many genetic variants have been found to have a linkage with genetic diseases, but the understanding of their functional roles in causing diseases are still limited. An international research team, including a biomedical scientist from City University of Hong Kong (CityU), has developed a high-throughput biological assay technique which enabled them to conduct a systematic analysis on the impact of nearly 100,000 genetic variants on the binding of transcription factors to DNA. Their findings provided valuable data for finding key biomarkers of type 2 diabetes for diagnostics and treatments. And they believe that the new technique can be applied to studies of variants associated with other genetic diseases.
04 Feb 2021
Cells replicate their genetic material and divide into two identical clones to perpetuate life. Some cells pause in the process with a single, undivided nucleus. When the cell resumes division after such a pause, the nucleus can become caught in the fissure, splitting violently, and killing both cells. But that is not always the case. Researchers from Hiroshima University in Japan are starting to understand how active nuclear displacement rescues cell death.
28 Dec 2020
Investigations of a cellular protein have uncovered a possible link with schizophrenia.
21 Dec 2020
Researchers baffled by an infant’s rare encephalitis case unusual in children found unheard-of mutations and a new way to examine the “immunity gene.”
20 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has presented the whole-genome sequence and analyses of the endangered whale shark (Rhincodon typus), the largest extant fish on Earth.
20 Nov 2020
A research team, affiliated with the Korea Genomics Center (KOGIC) at UNIST has released data from the initial phase of the Korean Genome Project (Korea1K), including information describing 1,094 whole genomes, along with 79 quantitative clinical traits.
19 Nov 2020
A repetitive DNA sequence that causes health risks when it malfunctions can now be watched inside living cells using a synthetic tool
04 Nov 2020
Innovative research by scientists at Duke-NUS Medical School has shed light on the mysterious role of long non-coding RNAs in the development of pancreatic cancer and suggests potential new targets for precision cancer therapies.
06 Oct 2020
Researchers at Kanazawa University report in Nature Communications the mechanism making some lung-cancer patients resistant to the drug osimertinib. In addition, they suggest a combined drug treatment resolving osimertinib resistance in the case of cancer cells expressing low amounts of AXL, a protein belonging to the class of receptor tyrosine kinases.
03 Oct 2020
A new apparatus improves how we study the effects of aiming high-field terahertz radiation at cells, with implications for regenerative medicine.
03 Jun 2020
A highly accurate machine learning tool could help doctors tailor individualized treatments for people with glioma brain tumours.
18 May 2020
Research at Kanazawa University, Theragen Etex Bio Institute and Seoul National University as reported in Nature Communications points towards pathways for the metastasis and malignant transitions that result from changes in the protein p53. The results suggest that the cooperative development of mutations in the proteins helps tumours spread and metastasis.
12 May 2020
In a recent study published in Molecular Cell, researchers at Kanazawa University report the role of cellular structures called PML bodies in regulating gene function
26 Mar 2020
In a recent study published in Autophagy, researchers at Kanazawa University show how abnormalities in a gene called TPR can lead to pediatric brain cancer
03 Mar 2020
DGIST joint research team identified the roles of 'Somatostatin,' which mediates the functions of GABAergic synaptic protein
14 Feb 2020
DGIST Professor Cheil Moon’s research team identified the molecular mechanism of innate olfactory behaviors. Clarified sensory defect accompanying neurodevelopmental disorder and cancer; will contribute to early diagnosis and improving anti-cancer drug side effects
23 Dec 2019
Professor Dennis Yuk Ming LO and Professor Rossa Wai Kwun CHIU from the Faculty of Medicine at The Chinese University of Hong Kong (CUHK) have been named the “Top 20 Translational Researchers of 2018” by the world-renowned scientific journal Nature Biotechnology. They are the only Hong Kong scientists on the list and it is the third consecutive year for Professor Lo to receive this honour.
27 Aug 2019
A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has analyzed the genetic map of Nomura’s jellyfish, scientifically known as Nemopilema nomurai, for the first time.
08 Jul 2019
Researchers in Japan have identified the potential genes responsible for coral bleaching caused by temperature elevation.
22 Feb 2019
Laboratory model breaks laws of heredity, opening up new research possibilities in genetics and synthetic biology.
12 Feb 2019
Study illustrates the links between brain energy metabolism and neuronal activity.
17 Oct 2018
The female of a sex-role reversed cave insect species Neotrogla has evolved a switching valve to receive more semen during mating, when a penis-like structure in the female anchors in the male “vagina.”
02 Aug 2018
A DNA probing technique clarifies the mechanism behind clonal reproduction of female dojo loach fish, also providing insight into the ancestral origin of the clonal population.
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