Medicine
News

17 Dec 2012
Nature Publishing Group
Genetic variants associated with hepatitis B virus (HBV)-related hepatocelullar carcinoma (HCC) are reported this week in Nature Genetics. Chronic HBV infection is a primary risk factor for HCC, one of the most common cancers worldwide.
12 Dec 2012
National Institute for Materials Science (NIMS)
In their recently published review article in the Science and Technology of Advanced Materials, Yasuhiko Iwasaki at Kansai University and Kazuhiko Ishihara at the University of Tokyo describe how developments in synthesis techniques have liberated the polymer MPC’s potential for a huge range of medical and biological applications.

10 Dec 2012
Nature Publishing Group
A method for reprogramming human cells in urine samples into neural progenitor cells is reported in a paper published in Nature Methods this week.
05 Dec 2012
National Institute for Materials Science (NIMS)
Tsukuba, Japan 5 Dec - Researchers in Japan have created a hybrid scaffold which promotes regeneration of skin in live animals while maintaining mechanical strength making it a promising material for future skin tissue engineering. This research was recently published in the Science and Technology of Advanced Materials.
04 Dec 2012
Toyohashi University of Technology
The cortical mechanisms governing speech are not well understood because it is extremely challenging to measure the activity of the brain in action, that is, during speech production. Researchers in Japan have found modulation of mu-rhythms in the cortex related to speech production.

03 Dec 2012
Asia Research News
The British High Commission in Singapore announces a Call for Proposals to support the initial stages of new collaborations between UK and Southeast Asia researchers in the field of Translational Skin Biology. Applications by 14th December 2012.

27 Nov 2012
The Agency for Science, Technology and Research (A*STAR)
Singapore, 27 Nov- A*STAR’s Institute of Microelectronics (IME) and SFC Fluidics, a USA microfluidics-based biomedical device development company, will be collaborating to develop a portable diagnostic tool for rapid triaging of traumatic brain injury (TBI) victims and to improve the treatment strategies.
19 Nov 2012
Toyohashi University of Technology
Aichi, Japan, 19 November 2012 - Over 180 participants attended the IRAGO Conference in Aichi, Japan which aimed to enhance mutual understanding between scientists, engineers and policy makers. Topics tackled ranged from energy and natural resources to public health and disaster prevention.

14 Nov 2012
The Agency for Science, Technology and Research (A*STAR)
Dusseldorf, Germany, 14 November 2012 – The Biofactory introduced today its ColoQuik line of label-free kits for the rapid colorimetric detection of protein-DNA interactions in biomedical research labs and the pharmaceutical industry. The kits are based on a unique technology developed by A*STAR Singapore.

09 Nov 2012
The Agency for Science, Technology and Research (A*STAR)
SINGAPORE, 9 November 2012: Singapore announces 8 biomedical sciences research programmes to advance understanding and treatment of diseases especially prevalent amongst the Asian population. This includes eye diseases, lung and stomach cancer and rare genetic diseases.
08 Nov 2012
The Agency for Science, Technology and Research (A*STAR)
A model that shows how connections in the brain must change to form memories could help to develop artificial cognitive computers
01 Nov 2012
Universiti Teknologi MARA (UiTM)
Alternative treatment for diabetics. Researchers Indah Mohd Amin, Nurhayati and Kaleswari from University Teknologi MARA, Malaysia studied the suitability of Abelmoschus Esculentus (AE) as complementary or as an alternative approach to treat diabetics.
01 Nov 2012
National Institute for Materials Science (NIMS)
Tsukuba, 1 November 2012 - Researchers in Japan have developed a technique which allows them to control and target drug delivery to specific sites of the body at specific times, thus reducing side effects and improving treatment dramatically. The results were published recently in the journal Science and Technology of Advanced Materials.
31 Oct 2012
Tokyo Institute of Technology
(Tokyo, 31 October 2012) Researchers at Tokyo Institute of Technology and the Weizmann Institute of Science identify a means of controlling biological processes that could help treatments for immune disease, neurological disorders and cancer.
25 Oct 2012
The Agency for Science, Technology and Research (A*STAR)
Glucose–amine rings turn star-shaped fluorescent dyes into powerful probes for imaging cancer cells in three dimensions.
11 Oct 2012
Hanyang University
An interview with Prof. Kwon of Hanyang University who leads research developments in five major electronics fields.
10 Oct 2012
Universiti Teknologi MARA (UiTM)
To prevent the risks in minimally invasive surgery procedures there has been considerable interest in using Master Slave System (MSS), a telesurgical system for catheter guide during interventional radiology. Here the researchers propose using a fail-safe telesurgical system.
28 Sep 2012
Hanyang University
An interview with Prof. Young-Ho Lee of Hanyang University who brought the concept of ‘cord blood transplantation’ to Korea with the first successful cord blood transplant in 1998.
28 Sep 2012
Hanyang University
Interview with Prof. Yoon of Hanyang University who discovered an innovative method for detecting anthrax
20 Sep 2012
Okayama University
(Okayama, Japan, 20 September 2012) This e-Bulletin highlights pioneering insights into water splitting/photosynthesis, analysis of the Itokawa asteroid brought to Earth by Japan's Hayabusa space probe, stemming the spread of cancer and identification of a rice transporter for manganese and cadmium uptake
20 Sep 2012
Okayama University
(Okayama, Japan, 20 September 2012) - Okayama University researchers demonstrate that cancer stem cells can be produced from normal stem cells for new therapies to combat cancer

12 Sep 2012
Universiti Teknologi MARA (UiTM)
University Teknologi MARA researchers conducted a study on Norovirus (NoV) in lettuces. The virus causes outbreaks of Gastroenteritis among children below age 5 in Malaysia.
11 Sep 2012
Asia Research News
Researchers from France and Thailand have trialled a dengue vaccine in over 4000 Thai children. While overall there was no difference between the number of dengue cases recorded following vaccination, secondary tests showed that the vaccine was effective against three of the four dengue viruses.

02 Sep 2012
Nature Publishing Group
A gene therapy approach for restoring cilia development and olfactory responses is reported online this week in Nature Medicine. These findings provide a proof-of-principle that gene therapy may be used in certain genetic disorders to rescue cilia development and restore sensory function.
27 Aug 2012
Tokyo Institute of Technology
(Tokyo, 27 August 2012) Tokyo Tech ‘s Yoshihiro Miyake and colleagues have developed an innovative, non-invasive therapeutic intervention that may improve the mobility, stability, and quality of life of Parkinson’s disease patients.
27 Aug 2012
Tokyo Institute of Technology
(Tokyo, 27 August 2012) The bulletin contains cutting research from fish collagen for cosmetics and medical applications to multi-petaflop supercomputing, and environmentally responsive organic materials.
24 Aug 2012
Tokyo Institute of Technology
(Tokyo, 24 August 2012) Tokyo Institute of Technology researchers show simpler versions of the universal genetic code can still function in protein synthesis. In addition to understanding early primordial organisms, the research could lead to applications preventing non-natural genetically modified materials from entering the natural world.

22 Aug 2012
Nature Publishing Group
Children of older fathers have a higher rate of new mutations according to a large genome-sequencing study published in this week’s Nature. The effect is an increase of roughly two new mutations per year for every additional year of father’s age at conception.
21 Aug 2012
Tokai University School of Medicine
Medical scientists at Tokai University School of Medicine in Japan announce the development of a new cancer therapy using ultra violet C (UVC) pulses of light. Details of these findings will be described by Johbu Itoh at the International Congress of Histochemistry and Cytochemistry (ICHC 2012), 26–29 August, 2012, Kyoto.

20 Aug 2012
Nature Publishing Group
The process by which male fruit flies learn to focus their courtship away from females that have already mated and towards eligible partners is deciphered in Nature this week. It seems that the mantra is simple: be promiscuous at first, but become more selective if a mating attempt fails.
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Giants in history
Henriette Bui Quang Chieu (1906 – 2012) was inspired to follow in her brother’s footsteps and become a doctor after losing her mother to tuberculosis. She studied in France and became the first Vietnamese woman to receive a medical degree. Upon her return to Vietnam, Bui was appointed head of the Department of Midwifery at Cho Lon Hospital in Ho Chi Minh City. A pioneer in gynaecology, she applied acupuncture techniques that she had learned in Japan to obstetrics. As Vietnam was still a French colony, Bui also lobbied for the rights of Vietnamese doctors, nurses, and patients.
Japanese biochemist Akira Endo (1933 – 2024) discovered the first statin, called mevastatin, which lowered cholesterol levels in the blood by inhibiting a key enzyme in the cholesterol biosynthesis pathway. His work laid the foundation for the development of statins to help patients lower their blood cholesterol levels and reduce their risk of heart disease or stroke.
Tu Youyou (born 30 December 1930) is a Chinese pharmaceutical scientist who was awarded the 2015 Nobel Prize in Physiology or Medicine for her work on extracting artemisin from sweet wormwood to treat malaria.
Filipina paediatrician and scientist Perla Santos-Ocampo (25 July 1931 – 29 June 2012) made important contributions to treatments and policies that curbed debilitating and sometimes deadly diarrhoea-related diseases and malnutrition in children.
Singaporean physician Oon Chiew Seng (1916 – 31 March 2022) advanced dementia care and research in Singapore, and co-founded the Apex Harmony Lodge, the nation’s first nursing home for residents with dementia.
Vietnamese surgeon Tôn Thất Tùng (10 May 1912 – 7 May 1982) developed a pioneering technique that reduced the risks and mortality rate of liver operations.
Michiaki Takahashi (17 February 1928 – 16 December 2013) was a Japanese virologist who developed the first chickenpox vaccine.
Irene Ayako Uchida’s (8 April 1917 – 30 July 2013) strides to understand genetic diseases such as Down syndrome paved the way for early screening of chromosomal abnormalities in foetuses.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
Maggie Lim (5 January 1913 – November 1995) was a Singaporean physician who promoted family planning and expanded the access to clinics to improve the quality of life for mothers and children in Singapore’s early days.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
The founder of the Adyar Cancer Institute in India, Muthulakshmi Reddy (30 July 1886 – 22 July 1968), fought to uplift women and girls from impoverished situations.
Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Archana Sharma (16 February 1932 - 14 January 2008) conducted research into plant and human genetics that expanded the understanding of both botany and human health. In relation to botany, she uncovered the means by which asexually-reproducing plants evolve into new species.
The first Thai woman to receive a degree in medicine, Margaret Lin Xavier (29 May 1898 – 6 December 1932), is best remembered for her compassion towards her less privileged patients.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
In 1915, Koichi Ichikawa along with pathologist Katsusaburo Yamagiwa became the first to prove that chronic exposure to chemicals can cause cancer.
In 1915, pathologist Katsusaburo Yamagiwa and his research assistant Koichi Ichikawa became the first to prove that chronic exposure to chemicals can cause cancer.
Ogino Ginko (3 March 1851 – 23 June 1913) was the first registered female doctor to practise modern medicine in Japan.
Syed Qasim Mehdi (13 February 1941 – 28 September 2016) was a Pakistani molecular biologist who was a founding member of the Human Genome Diversity Project (HGDP), which assessed human diversity by studying human migration, mutation rates, relationships between different populations, genes involved in height and selective pressure.
Salimuzzaman Siddiqui (19 October 1897 – 14 April 1994) was an artist and chemist from Pakistan whose research focused on natural products from plants.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Barry Paw (29 August 1962 – 28 December 2017) was a biologist and oncologist who discovered several novel genes and their functions in red blood cells.
Chika Kuroda (24 March 1884 – 8 November 1968) was a Japanese chemist whose research focussed on the structures of natural pigments.
Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
David T. Wong (born 1936) is a Hong Kong-born American neuroscientist who is best known for discovering the antidepressant drug fluoxetine, better known as Prozac.
Wu Lien-teh (10 March 1879 – 21 January 1960) was a Malaysian-born doctor who invented a mask that effectively suppressed disease transmission. Winning the prestigious Queen’s Scholarship enabled Wu to become the first Chinese student to study medicine at the University of Cambridge.
Minoru Shirota (April 23, 1899 – March 10, 1982) was a Japanese microbiologist who invented the popular fermented drink Yakult.
After witnessing death and suffering as a youth in his home village during World War II, Nguyễn Tài Thu (6 April 1931 – 14 February 2021) set his sights on alleviating pain by becoming a doctor. After studying Traditional Chinese Medicine in China in the 1950s, Thu returned to Vietnam to serve in military hospitals. Eventually, he became the country’s foremost practitioner of acupuncture, a technique he first learned by inserting needles into himself.
Fe Villanueva del Mundo (27 November 1911 – 6 August 2011) was a Filipina paediatrician who founded the Philippines’ first paediatric hospital.
Korean parasitologist Seung-Yull Cho (16 November 1943 – 27 January 2019) is remembered largely for his pioneering works to control infections caused by helminthic parasites and his contribution to journal publishing.
Filipino chemist and pharmacist Manuel A. Zamora (29 March 1870 – 9 July 1929) is best remembered for his discovery of the tiki-tiki formula to combat beriberi, a disease caused by Vitamin B1 deficiency.
Indian scientist and physician Upendranath Brahmachari (19 December 1873–6 February 1946) is best known for creating a drug called Urea Stibamine, used to safely and reliably treat visceral leishmaniasis (or Kala-azar), a severe infection caused by the Leishmania parasite.
Thai physician and conservationist Boonsong Lekagul (1907 – 1992) made major contributions to the preservation of his country’s wildlife.
The research of Filipino pharmaceutical chemist Luz Oliveros-Belardo (3 November 1906 – 12 December 1999) focussed on essential oils and other chemicals derived from native Philippine plants.
Ground-breaking cancer researcher Kamal Jayasing Ranadive (8 November 1917 – 11 April 2001) advanced the understanding of the causes of leukaemia, breast cancer and oesophageal cancer through the use of animal models. She was also among the first to recognise how susceptibility to cancer is linked to tumour-causing interactions between hormones and viruses.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
Tsai-Fan Yu (1911 – 2 March 2007) was a Chinese-American physician and researcher who was the first female full professor at Mount Sinai School of Medicine. She discovered that gout, a condition characterized by the painful inflammation of joints, was caused by elevated levels of uric acid in the bloodstream.
A Japanese surgeon, Tetsuzo Akutsu (20 August 1922 – 9 August 2007) built the first artificial heart capable of keeping an animal alive.
Min Chueh Chang (10 October 1908 – 5 June 1991) was a Chinese-American biologist who studied fertilization in mammalian reproduction.
Esther Park (1877-1910), born Kim Jeom-dong, was the first female Korean physician to practise modern medicine in Korea and trained the first generation of Korean female doctors.




























































