Medicine
News
21 Aug 2012
Tokai University School of Medicine
Medical scientists at Tokai University School of Medicine in Japan announce the development of a new cancer therapy using ultra violet C (UVC) pulses of light. Details of these findings will be described by Johbu Itoh at the International Congress of Histochemistry and Cytochemistry (ICHC 2012), 26–29 August, 2012, Kyoto.

20 Aug 2012
Nature Publishing Group
The process by which male fruit flies learn to focus their courtship away from females that have already mated and towards eligible partners is deciphered in Nature this week. It seems that the mantra is simple: be promiscuous at first, but become more selective if a mating attempt fails.
17 Aug 2012
The Agency for Science, Technology and Research (A*STAR)
Water plays a key role in the co-crystallization of active pharmaceutical ingredients

16 Aug 2012
Nature Publishing Group
Two new genetic variants associated with resistance to severe malaria are identified in a study published in Nature this week. These genetic variants may confer resistance by affecting certain steps involved in disease development. The variants may represent candidates for the development of medical control measures against malaria.

12 Aug 2012
Nature Publishing Group
A method for printing colours at the highest possible resolution is reported in a paper published online this week in Nature Nanotechnology. The resolution of about 100,000 dots per inch could be useful for high-resolution printing for security purposes or for high-density optical data storage.
06 Aug 2012
The Hong Kong Polytechnic University (PolyU)
Tapping into the power of natural ingredients for safer treatment is the next frontier in the battle against cancer. A recent breakthrough from HKPolyU uses tiger milk mushroom to prepare anti-tumor nanoparticles is bringing us one step closer.

05 Aug 2012
Nature Publishing Group
Genome sequencing of a global collection of Shigella sonnei or baciliary dysentery, in developing countries is reported in a study published in Nature Genetics. Their study provides insights into the course of recent shigellosis epidemics. S. sonnei are human-adapted E. coli responsible for approximately 150 million cases of dysentery each year.

01 Aug 2012
Nature Publishing Group
Two independent studies published in Nature this week identify specific subsets of cells in mouse tumours that seem to be responsible for the re-growth of tumours. These findings shed new light on the controversial issue of whether cancer stem cells exist in growing tumours and may have implications for potential therapies.

29 Jul 2012
Nature Publishing Group
Oceanic uptake of atmospheric carbon dioxide depends on climatically sensitive physical factors, such as winds and ocean currents, reports a study published online in Nature Geoscience this week.

26 Jul 2012
Nature Publishing Group
A large number of tropical forest protected areas are experiencing a decline in biodiversity, according to an analysis in Nature this week. These reserves are supposed to represent a final refuge for threatened species and natural ecosystem processes, as concerns about human impacts on tropical biodiversity grow.
26 Jul 2012
International Center for Materials Nanoarchitectonics (MANA)
Researchers in Japan demonstrate a new protein binding approach for effectively promoting bone regeneration. Current treatments for bone defects and bone tissue regeneration have significant limitations. Now a new method that immobilises a fusion protein in a hybrid collagen-polymer supportive scaffold shows promise for bone tissue engineering.
23 Jul 2012
National Institute for Materials Science (NIMS)
An artificial bone scaffold produced by researchers in South Korea could enhance the treatment of bone damage and defects through bone grafts.

22 Jul 2012
Nature Publishing Group
A freely swimming jellyfish replica made from silicone polymer and rat heart cells is reported this week in Nature Biotechnology. The study, which advances a quantitative and system-level approach to tissue engineering, provides new insights into the design of muscular pumps.
18 Jul 2012
The Agency for Science, Technology and Research (A*STAR)
Fluorescent dyes with aggregation-induced emission provide new probes for cancer diagnosis and therapy

18 Jul 2012
Asia Research News
New Pancreatic Cancer Animal Models to aid Novel Therapy Development. Austrianova Singapore announced today that they and their partners have created a mouse model that mimics human pancreatic cancer.

16 Jul 2012
Nature Publishing Group
Nanoparticle gels that deliver an immunostimulatory molecule and an inhibitor of an immunosuppressive factor to tumours over a period of a few days are reported this week in Nature Materials. When injected in melanoma tumours in mice, the nanoparticles delay tumour growth and significantly increase the survival time of the mice.

15 Jul 2012
Nature Publishing Group
Microbiota variation in the intestine correlates with health as well as with diet in elderly individuals, reports a paper in Nature this week. The work suggests that dietary adjustments could promote healthier ageing by modulating the gut microbiota.

12 Jul 2012
Nature Publishing Group
Research comparing 52 Native American populations along with 17 Siberian populations provides insight into migrations within the New World and is published online in Nature this week. David Reich and colleagues’ data suggest that the controversial hypothesis that the Americas were peopled in three migration waves may be true.

08 Jul 2012
Nature Publishing Group
The cellular migration that occurs in our bodies during early development works on the same principle as the healing of wounds in adulthood: cells move in large monolayer sheets responding to chemical cues. A paper in Nature suggests that there is an additional feedback mechanism at work in cell migration involving physical forces.

04 Jul 2012
Nature Publishing Group
Sequencing of a fetal genome using genetic material found circulating in the mother’s blood is described in Nature this week. Unlike a similar recently reported technique, the approach described this week doesn’t require knowledge of the father’s genetic information.
04 Jul 2012
The Agency for Science, Technology and Research (A*STAR)
Exploiting the early immune response in Chikungunya fever promises to provide protection.

01 Jul 2012
Nature Publishing Group
Greater functional connectivity between two brain regions previously implicated in the experience of pain predicts which back-pain patients will still be in pain a year after reporting problems, according to an article published in Nature Neuroscience this week.
28 Jun 2012
The Hong Kong Polytechnic University (PolyU)
The discovery of a new drug for liver cancer by researchers of The Hong Kong Polytechnic University (PolyU) and local medical practitioner has borne fruit. After completing clinical trials locally, the new drug known as "BCT-100" has become Hong Kong's first "Investigational New Drug" (IND) granted by the US Food and Drug Administration (FDA).

28 Jun 2012
Nature Publishing Group
Analysis of the teeth of a 2-million-year-old hominin known as Australopithecus sediba, a relative of modern humans, reveals that they ate leaves, fruits and bark. The results, reported in Nature this week, suggest that these early hominins lived in a woodland environment.

24 Jun 2012
Nature Publishing Group
Two new drug candidates for treating radiation poisoning are uncovered in a study this week. Hartmut Geiger and colleagues use a genetic screen to identify new regulators of radiation sensitivity in mice and discover that a pathway that controls blood clotting and inflammation unexpectedly provides protection against radiation damage.

20 Jun 2012
Nature Publishing Group
A Perspective article in this week’s Nature discusses concerns that were raised about making the data from two H5N1-related papers available and emphasizes the importance of ongoing research to advance our understanding of infectious diseases.

17 Jun 2012
Nature Publishing Group
A growing proportion of the public in Western democracies deny anthropogenic climate change, and experts assume that climate deniers need to be ‘converted’ to get them acting in support of mitigation policy. A study in Nature Climate Change this week questions such common assumptions.

14 Jun 2012
Nature Publishing Group
A large-scale resource for investigating microbial communities throughout the human body and an analysis of these data is reported in two studies in this week’s Nature. Microbial communities that live on and in the human body, collectively known as the ‘microbiome’, are thought to have a critical role in human health and disease.

10 Jun 2012
Nature Publishing Group
Clues to how a rare group of patients can resist infection by HIV are reported in a paper this week in Nature Immunology. So-called ‘elite controllers’ are able to retain normal immune function and undetectable levels of HIV infection despite regular exposure to the virus.

06 Jun 2012
Nature Publishing Group
A comprehensive analysis of endangered species threat records and of international trade patterns shows how consumers in developed countries drive biodiversity threats in developing countries. The study reveals that, excluding invasive species, 30% of global species threats are due to international trade.
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Giants in history
Henriette Bui Quang Chieu (1906 – 2012) was inspired to follow in her brother’s footsteps and become a doctor after losing her mother to tuberculosis. She studied in France and became the first Vietnamese woman to receive a medical degree. Upon her return to Vietnam, Bui was appointed head of the Department of Midwifery at Cho Lon Hospital in Ho Chi Minh City. A pioneer in gynaecology, she applied acupuncture techniques that she had learned in Japan to obstetrics. As Vietnam was still a French colony, Bui also lobbied for the rights of Vietnamese doctors, nurses, and patients.
Japanese biochemist Akira Endo (1933 – 2024) discovered the first statin, called mevastatin, which lowered cholesterol levels in the blood by inhibiting a key enzyme in the cholesterol biosynthesis pathway. His work laid the foundation for the development of statins to help patients lower their blood cholesterol levels and reduce their risk of heart disease or stroke.
Tu Youyou (born 30 December 1930) is a Chinese pharmaceutical scientist who was awarded the 2015 Nobel Prize in Physiology or Medicine for her work on extracting artemisin from sweet wormwood to treat malaria.
Filipina paediatrician and scientist Perla Santos-Ocampo (25 July 1931 – 29 June 2012) made important contributions to treatments and policies that curbed debilitating and sometimes deadly diarrhoea-related diseases and malnutrition in children.
Singaporean physician Oon Chiew Seng (1916 – 31 March 2022) advanced dementia care and research in Singapore, and co-founded the Apex Harmony Lodge, the nation’s first nursing home for residents with dementia.
Vietnamese surgeon Tôn Thất Tùng (10 May 1912 – 7 May 1982) developed a pioneering technique that reduced the risks and mortality rate of liver operations.
Michiaki Takahashi (17 February 1928 – 16 December 2013) was a Japanese virologist who developed the first chickenpox vaccine.
Irene Ayako Uchida’s (8 April 1917 – 30 July 2013) strides to understand genetic diseases such as Down syndrome paved the way for early screening of chromosomal abnormalities in foetuses.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
Maggie Lim (5 January 1913 – November 1995) was a Singaporean physician who promoted family planning and expanded the access to clinics to improve the quality of life for mothers and children in Singapore’s early days.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
The founder of the Adyar Cancer Institute in India, Muthulakshmi Reddy (30 July 1886 – 22 July 1968), fought to uplift women and girls from impoverished situations.
Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Archana Sharma (16 February 1932 - 14 January 2008) conducted research into plant and human genetics that expanded the understanding of both botany and human health. In relation to botany, she uncovered the means by which asexually-reproducing plants evolve into new species.
The first Thai woman to receive a degree in medicine, Margaret Lin Xavier (29 May 1898 – 6 December 1932), is best remembered for her compassion towards her less privileged patients.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
In 1915, Koichi Ichikawa along with pathologist Katsusaburo Yamagiwa became the first to prove that chronic exposure to chemicals can cause cancer.
In 1915, pathologist Katsusaburo Yamagiwa and his research assistant Koichi Ichikawa became the first to prove that chronic exposure to chemicals can cause cancer.
Ogino Ginko (3 March 1851 – 23 June 1913) was the first registered female doctor to practise modern medicine in Japan.
Syed Qasim Mehdi (13 February 1941 – 28 September 2016) was a Pakistani molecular biologist who was a founding member of the Human Genome Diversity Project (HGDP), which assessed human diversity by studying human migration, mutation rates, relationships between different populations, genes involved in height and selective pressure.
Salimuzzaman Siddiqui (19 October 1897 – 14 April 1994) was an artist and chemist from Pakistan whose research focused on natural products from plants.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Barry Paw (29 August 1962 – 28 December 2017) was a biologist and oncologist who discovered several novel genes and their functions in red blood cells.
Chika Kuroda (24 March 1884 – 8 November 1968) was a Japanese chemist whose research focussed on the structures of natural pigments.
Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
David T. Wong (born 1936) is a Hong Kong-born American neuroscientist who is best known for discovering the antidepressant drug fluoxetine, better known as Prozac.
Wu Lien-teh (10 March 1879 – 21 January 1960) was a Malaysian-born doctor who invented a mask that effectively suppressed disease transmission. Winning the prestigious Queen’s Scholarship enabled Wu to become the first Chinese student to study medicine at the University of Cambridge.
Minoru Shirota (April 23, 1899 – March 10, 1982) was a Japanese microbiologist who invented the popular fermented drink Yakult.
After witnessing death and suffering as a youth in his home village during World War II, Nguyễn Tài Thu (6 April 1931 – 14 February 2021) set his sights on alleviating pain by becoming a doctor. After studying Traditional Chinese Medicine in China in the 1950s, Thu returned to Vietnam to serve in military hospitals. Eventually, he became the country’s foremost practitioner of acupuncture, a technique he first learned by inserting needles into himself.
Fe Villanueva del Mundo (27 November 1911 – 6 August 2011) was a Filipina paediatrician who founded the Philippines’ first paediatric hospital.
Korean parasitologist Seung-Yull Cho (16 November 1943 – 27 January 2019) is remembered largely for his pioneering works to control infections caused by helminthic parasites and his contribution to journal publishing.
Filipino chemist and pharmacist Manuel A. Zamora (29 March 1870 – 9 July 1929) is best remembered for his discovery of the tiki-tiki formula to combat beriberi, a disease caused by Vitamin B1 deficiency.
Indian scientist and physician Upendranath Brahmachari (19 December 1873–6 February 1946) is best known for creating a drug called Urea Stibamine, used to safely and reliably treat visceral leishmaniasis (or Kala-azar), a severe infection caused by the Leishmania parasite.
Thai physician and conservationist Boonsong Lekagul (1907 – 1992) made major contributions to the preservation of his country’s wildlife.
The research of Filipino pharmaceutical chemist Luz Oliveros-Belardo (3 November 1906 – 12 December 1999) focussed on essential oils and other chemicals derived from native Philippine plants.
Ground-breaking cancer researcher Kamal Jayasing Ranadive (8 November 1917 – 11 April 2001) advanced the understanding of the causes of leukaemia, breast cancer and oesophageal cancer through the use of animal models. She was also among the first to recognise how susceptibility to cancer is linked to tumour-causing interactions between hormones and viruses.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
Tsai-Fan Yu (1911 – 2 March 2007) was a Chinese-American physician and researcher who was the first female full professor at Mount Sinai School of Medicine. She discovered that gout, a condition characterized by the painful inflammation of joints, was caused by elevated levels of uric acid in the bloodstream.
A Japanese surgeon, Tetsuzo Akutsu (20 August 1922 – 9 August 2007) built the first artificial heart capable of keeping an animal alive.
Min Chueh Chang (10 October 1908 – 5 June 1991) was a Chinese-American biologist who studied fertilization in mammalian reproduction.
Esther Park (1877-1910), born Kim Jeom-dong, was the first female Korean physician to practise modern medicine in Korea and trained the first generation of Korean female doctors.

















































