Science

New research reveals how disrupted energy production in the kidneys contributes to progressive kidney disease in diabetes.

The latest ‘large language model’ artificial intelligence system, GPT-4, could aid chemistry researchers, but limitations reveal the need for improvements.

Osaka Metropolitan University scientists, in cooperation with researchers from the National Astronomical Observatory of Japan, have captured cosmic-ray extensive air showers with unprecedented precision using the prime-focus wide field camera mounted on the Subaru Telescope, situated atop Mauna Kea in Hawaii. Analyzing approximately 17,000 images captured between 2014 and 2020, they pinpointed 13 images containing extensive air showers, with a number of particle tracks far exceeding the usual count.

Researchers from Osaka University developed wirelessly powered soil moisture sensing technology that will help meet the needs of sustainable precision agriculture. Both the soil moisture content and the position of each sensor are readily detected and transmitted, even at high sensor densities. The sensors are largely biodegradable and can be tilled into the soil at the end of the crop season. This work might help farmers allocate resources to cropland in a timely, targeted manner.

Researchers from the Institute of Industrial Science, The University of Tokyo, synthesize a two-center zinc complex that absorbs visible light as a solid and in solution.

Hunting for supermassive black holes, Coastal survival at risk, Calcium and dead cell clean-up, Two naps are better than one & Pineapple leaf prosthetics. Read all in the latest Editor's Choice.

Acoels have been found to host a wide diversity of symbiotic, photosynthetic microalgae.

Insect cyborgs may sound like something straight out of the movies, but hybrid insect computer robots, as they are scientifically called, could pioneer a new future for robotics. It involves using electrical stimuli to control an insect’s movement. Now, an international research group has conducted a study on the relationship between electrical stimulation in stick insects' leg muscles and the resulting torque (the twisting force that causes the leg to move).

Researchers from Osaka University have developed a data-driven AI algorithm for controlling the heating and cooling of an office building. The system does not require ambient sensors or specific knowledge of the building’s rooms. During heating operations, the system was able to achieve energy savings of up to 30%, which can represent significant reductions to cost and environmental impact.

Friction, an everyday phenomenon, has perplexed scientists for centuries. Though extensively researched, our　understanding remains fragmented, primarily due to the multifaceted interactions that span across varying scales.　Achieving an accurate grasp of the precise contact conditions between objects has been a longstanding challenge, a feat recently made possible through advancements in scanning probe microscopy.

The annual burning of crop residue in India causes widespread air pollution, particularly in the northwestern regions. A group of international researchers has used low-cost yet reliable instruments to gauge the effects of air pollution in these areas, making it the first quantitative study of its kind.

Observations during two flybys by the Mio spacecraft as part of the BepiColombo International Mercury Exploration Project have revealed that chorus waves occur quite locally in the dawn sector of Mercury. Mercury's magnetic field is about 1% of that of Earth, and it was unclear whether chorus waves would be generated like on Earth. The present study reveals that the chorus waves are the driving source of Mercury’s X-ray auroras, whose mechanism was not understood.

The authors discovered a shorter isoform of Rubicon called RUBCN100, which enhances autophagy in B cells.

The authors identified a structure in the circadian mRNA Period2 that affects the sleep-wake cycle. The results indicate how translation and post-transcriptional processes influence the body’s internal clock and its impact on sleep patterns.

Researchers at Osaka Metropolitan University have succeeded in printing uniformly sized droplets with a diameter of approximately 100 µm using a liquid film of fluorescent ink. This ink, with a viscosity roughly 100 times that of water, was irradiated with an optical vortex, resulting in prints of exceptional positional accuracy at the micrometer scale.

Concave, umbrella-like metal complexes provide space to enable the largest molecular rotor operational in the solid-state.

A team led by researchers at SANKEN (The Institute of Scientific and Industrial Research), at Osaka University has used neutron crystallography to image all of the atoms in a radical intermediate of a copper amine oxidase enzyme. They disclosed previously unknown details, such as precise conformational changes, that help to explain the enzyme's biochemistry. This work might help researchers engineer enzymes that facilitate unusual chemistry or are highly efficient at room temperature that are useful in chemical industry.

An international group of researchers have discovered a previously unknown species of large foraminifer, shedding new light on the ecological evolution and biodiversity of coral reefs in the Ryukyu Islands.

Researchers led by Osaka University developed a novel genome editing technique known as NICER, which results in significantly fewer off-target mutations than CRISPR/Cas9 editing. The technique uses a different type of enzyme that makes single-stranded “nicks” in the DNA. Repair of these nicks is more efficient and accurate than repair of double-strand breaks caused by the current CRISPR/Cas9 editing. This technique represents a novel approach for the treatment of genetic diseases caused by heterozygous mutations.

Lab-based studies reveal how carbon atoms diffuse on the surface of interstellar ice grains to form complex organic compounds, crucial to reveal the chemical complexity in the universe.

Scientists have found that extracellular calcium mediates the activation of a membrane protein that waves the flag signalling cell death

Patients with a specific form of chronic indigestion react differently to images of food, compared to healthy control subjects or patients with irritable bowel syndrome.

Elusive fundamental particles called neutrinos are predicted to interact unexpectedly with photons under extreme conditions.

Researchers at Osaka Metropolitan University have developed a measurement technique that rapidly measures the number of viable bacteria in food products. They have succeeded in drastically reducing the inspection time from 2 days to about 1 hour. With this technology, it will be possible to confirm food safety before shipment from factories and prevent food poisoning.

Capturing carbon dioxide, Shells go nuclear, Worms surf electric fields, Brain repair & Creating matter from light. Plus from our blog: Monitoring research for further impact. Read all in the latest Editor's Choice.

Study addresses gaps in understanding of swine influenza A virus evolution and highlights need for early warning of disease emergence

DishBrain reveals how human neurons work together to process information. Living model of brain could give insights into the mechanisms of how we understand and experience the world.

Researchers from Osaka University have revealed that the expression of a specific isoform of GREB1 Is4 is induced in malignant melanoma cells by the melanocyte-specific transcription factor, MITF. They revealed that GREB1 Is4 stimulates pyrimidine biosynthesis and promotes cancer cell proliferation. Furthermore, the anti-tumor effect of antisense nucleic acids against GREB1 showed a potential new modality for malignant melanoma.

Researchers at Kanazawa University report in Cell Reports how alterations in the nuclear pores lead to the degradation of anti-tumor proteins.

Survey observations with the Subaru Telescope have led to the discovery of 22 quasars in the very distant universe. Their space density indicates the rapid emergence of supermassive black holes soon after the Big Bang, providing strong constraints on models of when, where, and how they formed and grew in cosmic space-time. The results also indicate a small quasar contribution to cosmic reionization, a major phase transition of the early universe.