Brain

Diagnosis of Alzheimer's disease, the most common type of dementia, is not easy for its overlapping signs with normal ageing. A collaborative research by City University of Hong Kong (CityU) and Johns Hopkins University has developed a new non-invasive molecular imaging approach based on Magnetic Resonance Imaging (MRI) to dynamically measure glucose level changes in the brain lymphatic system. Their discovery may help in identifying Alzheimer's disease at early stages so that treatments can start as soon as possible.

It is no secret that genetic factors play a role in determining whether children have neurodevelopmental disorders. Maternal exposure to drugs and viral or bacterial illnesses can be detrimental too.

A new technique allows researchers to test how the deformation of tiny train track-like cell proteins affects their function. The findings could help clarify the roles of deformed “microtubules” in traumatic brain injuries and in neurological diseases like Parkinson’s.

DGIST joint research team identified the roles of 'Somatostatin,' which mediates the functions of GABAergic synaptic protein

Mayor Cheol-ho Song (Ulsan, South Korea) visited the startup facilities of Ulsan National Institute of Science and Technology (UNIST) on January 4, 2020.

- Participants of 'International SYNAPSE Project', DGIST & POSTECH sign an MOU to build a joint cooperation system

DGIST Professor Cheil Moon’s research team identified the molecular mechanism of innate olfactory behaviors. Clarified sensory defect accompanying neurodevelopmental disorder and cancer; will contribute to early diagnosis and improving anti-cancer drug side effects

West Nile virus (WNV) inhibits autophagy — an essential system that digests or removes cellular constituents such as proteins — to induce the aggregation of proteins in infected cells, triggering cell death and brain inflammation (encephalitis), according to Hokkaido University researchers.

A new compound could help doctors detect epileptic foci in the living human brain as well as further the understanding of psychiatric disease.

A resource for journalists to find stories and sources. Focus On: Brain highlights research and experts exploring questions ranging from basic structure and function, to technology, diseases and treatments.

First-of-its-kind study led by Duke-NUS Medical School and National Neuroscience Institute (NNI) applies experimental methodology using human neural cells and brain organoids to investigate mechanism underlying epileptic seizures in Angelman syndrome, an autism spectrum disorder.

A hyperactive gene response to Japanese encephalitis virus infection ultimately leads to brain inflammation.

The drugs helped mice and humans recall long-term object memories.

An implantable device has the potential to revolutionize how neuroscientists study the brain and treat diseases.

A small molecule could hold the key to tackling the protein build-up in nerve cells that occurs in several devastating neurological disorders.

Much-needed insight into raising young children with autism in Malaysia highlights the need to improve local research, awareness, acceptance and support services.

New findings could lead the way towards treatments for intellectual disability in Down syndrome.

Over 70% of rare disease patients and non-patients are aware of the patient registry but the participation rate accounted for less than 30%, according to a recent survey of the public’s acknowledgement of and participation in the rare disease patient registry.

Despite great investments, an effective drug-based treatment for Alzheimer’s disease, the most common form of dementia among the elderly, remains elusive. Scientists led by Duke-NUS Medical School, in collaboration with Monash University, have published an online atlas of gene expressions at single-cell level in Alzheimer’s disease brains, aiming to boost to efforts to identify gene targets for drug development.

When a fly eats sugar, a single brain cell sends simultaneous messages to stimulate one hormone and inhibit another to control glucose levels in the body. Further research into this control system with remarkable precision could shed light on the neural mechanisms of diabetes and obesity in humans.

Hokkaido University researchers have shown how chronic pain leads to suppression of the brain reward system.

Professor Eun-Kyoung Kim’s team in the Department of Brain and Cognitive Sciences discovered the mechanism underlying the regulation of energy metabolism by hypothalamic tanycyte. Proposed a new research direction to develop an enhanced obesity treatment.

Differential changes in brain functional network connectivity in people with mild cognitive impairment may aid early tracking of Alzheimer’s disease and cerebrovascular disease.

A recent study led by researchers from the National University of Singapore revealed that regular tea drinkers have better organised brain regions compared to non-tea drinkers.

An international team of researchers, affilated with UNIST has identified a new gene that causes drug resistance against Novartis’s breakthrough cancer drug, Gleevec (Active ingredient: imatinib).

A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has demonstrated new solvent-free, single lithium-ion conducting COF.

The protein that revives injured nerve cells was discovered. It is expected to present a new direction in the development of therapeutic agents for regenerating damaged brain or spinal cord nerves.

Chronic stress induces autophagic death of adult hippocampal neural stem cells (NSCs). Expected to offer new opportunities for development of early treatment options for stress-associated brain diseases.

As people age, the way different areas of their brain communicate with one another change, affecting thought processes and attention span.

Researchers in Singapore have discovered the mechanism behind how neural stem cells in fruit flies are activated to stimulate the generation of new brain cells.