Medicine

First-of-its-kind study led by Duke-NUS Medical School and National Neuroscience Institute (NNI) applies experimental methodology using human neural cells and brain organoids to investigate mechanism underlying epileptic seizures in Angelman syndrome, an autism spectrum disorder.

A new method could speed up drug discovery and lead to purer, side-effect-free medications.

A new approach uses two types of stem cells to repair both heart muscle and blood vessels damaged during severe heart attacks.

A team of researchers from the National University of Singapore has developed a personalised assessment tool which can detect the incidence of cancer, predict patient survivability and determine patient suitability for immunotherapy cancer treatment.

The war against antibiotic resistance requires a conceptual revision, namely design and creation of new types of degradable antibiotics with novel intracellular interactions, says Nobel Prize in Chemistry (2009) laureate Ada Yonath.

The drugs helped mice and humans recall long-term object memories.

A small molecule could hold the key to tackling the protein build-up in nerve cells that occurs in several devastating neurological disorders.

New findings could lead the way towards treatments for intellectual disability in Down syndrome.

Malaria parasites transform healthy red blood cells into rigid versions of themselves that clump together, hindering the transportation of oxygen. The infectious disease affects more than 200 million people across the world and causes nearly half a million deaths every year, according to the World Health Organization’s 2018 report on malaria. Until now, however, researchers did not have a strong understanding of how the parasite so effectively infiltrated a system’s red blood cells.

Despite great investments, an effective drug-based treatment for Alzheimer’s disease, the most common form of dementia among the elderly, remains elusive. Scientists led by Duke-NUS Medical School, in collaboration with Monash University, have published an online atlas of gene expressions at single-cell level in Alzheimer’s disease brains, aiming to boost to efforts to identify gene targets for drug development.

Salimuzzaman Siddiqui (19 October 1897 – 14 April 1994) was an artist and chemist from Pakistan whose research focused on natural products from plants.

Congratulations to all the winners of 11th Medical Undergraduates’ Annual Scientific Research Meeting 2019 in Universiti Kebangsaan Malaysia. Below is the list of winners according to the categories with respective research titles.

Foremost society of kidney specialists highlights Singapore-led global study to better understand diabetes complications and reduce their prevalence.

Join us at the Singapore FinTech Festival + Singapore Week of Innovation and Technology 2019 (SFF x SWITCH)

A scientific study of African populations discovers that the beta-amyloid gene is associated with an increased risk of the most common form of glaucoma.

The event will take place from 20-21 November 2019 at the International Convention Centre, Sydney, Australia. Organised by Healthcare Information and Management Systems Society (HIMSS).

Four young researchers from The Chinese University of Hong Kong (CUHK) have been awarded China's Excellent Young Scientists Fund 2019. Each of them will receive a funding of RMB1.3 million to directly support their scientific research projects in Hong Kong to a maximum period of three years.

The Faculty of Medicine of The Chinese University of Hong Kong (CUHK) conducted the world’s first study to investigate the association between unrecognised obstructive sleep apnoea (OSA) and postoperative cardiovascular complications. Results showed that patients with unrecognised severe OSA have a two-fold increased risk of postoperative cardiovascular complications compared to those without the disorder. The study has recently been published in the Journal of the American Medical Association (JAMA), suggesting that preoperative OSA screening should be considered in clinical practice to lower the risk of postoperative cardiovascular events.

Development of novel agonist antibodies to treat cancer by collaboration between academia and industry

When a fly eats sugar, a single brain cell sends simultaneous messages to stimulate one hormone and inhibit another to control glucose levels in the body. Further research into this control system with remarkable precision could shed light on the neural mechanisms of diabetes and obesity in humans.

A research team from the School of Chinese Medicine at Hong Kong Baptist University (HKBU) has successfully developed a novel aptamer, i.e. a single-stranded piece of DNA, for the treatment of osteogenesis imperfecta (OI) with the aid of artificial intelligence (AI) technology. It is the first time a drug in Hong Kong has been granted orphan drug designation by the US Food and Drug Administration (FDA).

A recent study conducted by the Department of Obstetrics and Gynaecology of the Faculty of Medicine at The Chinese University of Hong Kong (CUHK) has validated the use of the UK Fetal Medicine Foundation (FMF) triple test for the prediction of preterm preeclampsia at 11-13 weeks’ gestation in a large Asian population. The findings have been published in the international journal American Journal of Obstetrics & Gynecology.

A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells (GICs) has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity.

The world’s first “AI-enabled Portable Quantitative Phase Microscope for Blood Testing” is one of the five innovative projects to be showcased by The Chinese University of Hong Kong (CUHK) in the coming Hong Kong Electronics Fair (Autumn Edition) 2019 at the Hong Kong Convention and Exhibition Centre from 13 to 16 October. This project is able to provide low-cost, fast and high efficiency blood testing technology in general clinics and underdeveloped areas.

Healthcare and Information Management Systems Society Asia Pacific (HIMSS APAC) and Elsevier are proud to announce the finalists for the Asia Pacific HIMSS-Elsevier Digital Healthcare Award

Conference & Exhibition is organised by the Healthcare and Information Management Systems Society Asia Pacific (HIMSS APAC), and is supported by the Ministry of Public Health Thailand.

X-rays could be tuned to deliver a more effective punch that destroys cancer cells and not harm the body.

The Hong Kong Polytechnic University (PolyU) has developed a new class of antibiotic drug candidates which has high potential to be developed into a new generation of antibiotics fighting against multi-drug resistant superbugs including methicillin-resistant Staphylococcus aureus (MRSA).

Researchers from Duke-NUS Medical School, in collaboration with the Agency for Science, Technology and Research’s Bioinformatics Institute, and the University of Texas Medical Branch, USA, have discovered that the dengue virus changes its shape through mutations in Envelope protein to evade vaccines and therapeutics. The study also gives insights on the types of treatment strategies to use at different stages of infection. This could give rise to new approaches in vaccine development and treatment for dengue disease.

The Department of Obstetrics and Gynaecology of the Faculty of Medicine at The Chinese University of Hong Kong (CUHK) has successfully introduced a new genome sequencing technique for prenatal invasive genetic diagnosis. It offers enhanced sensitivity and accuracy of diagnosing lethal and severe congenital disorders through precise detection of pathogenic microdeletion or microduplication in the fetus, compared with the current practice karyotyping analysis and chromosomal microarray analysis (as known as fetal DNA chip testing). The team conducted a study on the innovation and the findings were recently published on the international journal Genetics in Medicine.