06 Aug 2020
Researchers from the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) have recently conducted a study to investigate the impact of liver injury on clinical outcomes in COVID-19 patients. Data from over 1,000 COVID-19 patients in Hong Kong was analysed and liver injury was found in around 20% of the patients. The estimated risk of COVID-19 patients with liver injury experiencing adverse clinical outcomes such as intensive care unit (ICU) admission, use of invasive mechanical ventilation or death was almost eight times of other patients. It is suggested that liver function monitoring is important regarding its association with adverse clinical outcomes in COVID-19 patients. These findings have been published recently in the world-renowned medical journal Gut. In view of the high prevalence of various chronic liver diseases in the Asia-Pacific region, CU Medicine’s researchers led a group of experts from Mainland China, Japan, Singapore and Australia to issue a position statement on the management of COVID-19 patients with liver derangement. The statement has been published recently in another international medical journal The Lancet Gastroenterology & Hepatology.
05 Aug 2020
Community rehabilitation; psychological impact of caregiving emerges as top interests
05 Aug 2020
The somatic nuclear protein kinase VRK-1 increases the worm’s lifespan through AMPK activation, and this mechanism can be applied to promoting human longevity, the study reveals.
04 Aug 2020
Recurrent miscarriages (RM) cause frustration and trauma to couples who want to have a child. However, not all couples can find out about the underlying reasons because of medical constraints. The Department of Obstetrics and Gynaecology (O&G) of the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) has successfully developed a new genome sequencing test called ChromoSeq to identify the genetic defects for married couples, who suffered from RM. When compared with the conventional karyotyping analysis, ChromoSeq offers greater accuracy in detecting potential genetic abnormalities associated with RM in affected couples. The team conducted a study on the innovation and the findings were recently published in the international journal American Journal of Human Genetics.
04 Aug 2020
Prognosis describes how serious a patient’s cancer is and his or her chance of survival. A genetic biomarker is a clinically useful tool to help estimate the state of the disease. A study, conducted by the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine), has identified a gene called GPR18 which can be a biomarker to help form the prognosis for a patient in nine cancer types. The research team has also provided new insights into B-cells for a cancer patient’s prognosis. The findings were recently published in the international scientific journal Communications Biology - Nature.
30 Jul 2020
A study conducted over the past 18 years has found differences between lead exposure effects in young Japanese boys versus girls.
30 Jul 2020
In a May 2020 Webinar, Dr. Sam Shah, Global Digital Health Advisor and Consultant with UK’s National Health System (NHS) discusses how the COVID-19 pandemic is reshaping healthcare with technology, specifically the response of UK’s NHS.
29 Jul 2020
COVID19 is teaching us one more new lesson – to look for new-onset diabetes and other non-communicable diseases in COVID19 patients by post-COVID19 vigilance.
27 Jul 2020
Epstein-Barr virus rewires host epigenome to turn on latent genetic enhancers that activate proto-oncogenes, leading to tumorigenesis in stomach cancer
27 Jul 2020
A research group has developed a new, lightweight and motor-less device that can be easily attached to an ankle support device - otherwise known as an ankle foot orthosis (AFO). The new device will aid stroke patients in their rehabilitation, improving their walking and preventing falls.
27 Jul 2020
The COVID-19 pandemic has thrown up unimaginable challenges for healthcare workers. Even simple outpatient procedures such as endoscopies can expose staff to the risk of infection.
20 Jul 2020
Environmental pollutants threaten the health of marine mammals. This study established a novel cell-based assay using the fibroblasts of a finless porpoise stranded along the coast of the Seto Inland Sea, Japan, to better understand the cytotoxicity and the impacts of environmental pollutants on the porpoise population. The results revealed that the concentrations of PCBs and DDTs which accumulated in the porpoise are likely to have an adverse effect at the cellular level.
13 Jul 2020
Acute kidney injuries can sometimes trigger the deterioration of small blood vessels and capillaries, leading to chronic kidney disease. But, this process is not completely understood. Now, for the first time, researchers from Daegu Gyeongbuk Institute of Science and Technology, Korea, in collaboration with teams from the University of Pittsburgh and University of Pittsburgh Medical Center, USA, have successfully used ultrasound super-resolution (USR) imaging to observe this process in live mice, revealing the promise of USR as a powerful diagnostic and research tool, and enhancing understanding of the disease.
09 Jul 2020
Researchers from the School of Biomedical Sciences of the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) have recently applied an advanced statistical approach to analyse risk factors that may be causally related to COVID-19 infection. Results suggested that diabetes may be a risk factor leading to increased susceptibility to or severity of COVID-19 infection through changes in ACE2 expression, which is a key receptor for the virus. A substantial proportion of COVID-19 death cases in Hong Kong suffered from diabetes. There is an urgent need to confirm risk factors and the mechanisms in order to protect the susceptible groups and identify effective treatments. The current study results were recently published in the international scientific journal Diabetes Care.
07 Jul 2020
The JUL 2020 regular issue of the Journal of Humanities & Social Sciences Research (JHSSR), Volume 2 (1) JUL. 2020 has been published ahead of time on 30 Jun 2020 and is now live at the Journal’s webpage.
02 Jul 2020
A method that involves infecting liver cells with mosquito-bred parasites could improve the study of malaria in India.
30 Jun 2020
Digital edition of CAREhab – Singapore Rehabilitation Conference 2020 postpones to 17 – 18 July 2020 in light of Singapore General Elections
26 Jun 2020
An International Islamic University Malaysia study highlights the need for strong oral hygiene awareness among school staff caring for disabled children.
19 Jun 2020
The newly established Institute of Health Equity of The Chinese University of Hong Kong (CUHK) has collaborated with the Jockey Club School of Public Health and Primary Care of the Faculty of Medicine at CUHK in a study which investigates the effects of housing affordability on physical and mental health in Hong Kong. The findings show that unaffordable housing worsens the physical and mental health of Hong Kong people, and the relative deprivation of necessities has a mediating role between housing affordability and health. It is the first “health equity” study of its kind in Asia and the results were published in the Journal of Epidemiology and Community Health.
19 Jun 2020
The Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) has recently conducted a global survey to examine the impact of the COVID-19 pandemic on urological care. This is the world’s first survey of its kind and includes a large sample of urology professionals from 6 continents. Results from over 1,000 participants showed that on average 28% of urology outpatient clinics, 30% of outpatient investigations and procedures, and 31% of urological surgeries had a delay of more than 8 weeks. The degree of cut-down of urological services increased with the degree of COVID-19 outbreak.
19 Jun 2020
Have you ever thought about why some people are more vulnerable to catching a virus? And why some get more severe infection than others? Gut microbiota, which is a fine balance between good and bad bacteria, regulates our immune system. Imbalance in gut microbiota (dysbiosis) will make us susceptible to infections.
18 Jun 2020
* CAREhab 2020 in conjunction with 6th Singapore Rehabilitation Conference to take place virtually via tech-enabled CAREhab GO platform live on 10-11 July * Delegates to have full access to digital library of video content and exhibition showcase in their own time from 10 July 2020 to February 2021, meeting convenient learning needs
17 Jun 2020
The journal provides a fast and convenient route to the most recently published articles in your subject areas. It's important to stay alert!
12 Jun 2020
Researchers at the University of Tsukuba and RIKEN in Japan spark a hibernation-like state in mice—a species that does not naturally hibernate
04 Jun 2020
Researchers from University of Tsukuba and the University of Tokyo identify neurons responsible for memory consolidation during REM sleep
03 Jun 2020
A highly accurate machine learning tool could help doctors tailor individualized treatments for people with glioma brain tumours.
29 May 2020
An international collaborative team from PROS Ehime University and CellFee Science, Japan; the Walter and Eliza Hall Institute, Australia; Pasteur Institute, France; and Foundation for Innovative New Diagnostics, Switzerland developed a new diagnostic blood test which detects recent exposure to ‘vivax’ malaria. The new test can also identify people who may harbor dormant liver-stage malaria parasites, which can cause illness. This new diagnostic approach has the potential to enhance malaria surveillance and accelerate elimination.
28 May 2020
A team of scientists and researchers from A*STAR’s Singapore Immunology Network and Jinan University, Guangzhou, have deciphered human embryonic immune cell development and discovered how the earliest macrophages in humans, a type of white blood cell of the immune system, stems from a distinct embryonic source and not the bone marrow.
27 May 2020
A team of young researchers led by Professor JIANG Yangzi, Research Assistant Professor at the Institute for Tissue Engineering and Regenerative Medicine (iTERM) and the School of Biomedical Sciences (SBS) at The Chinese University of Hong Kong (CUHK), has recently been granted funding from the National Key Research and Development (R&D) Programme. It is the first team in Hong Kong to receive national-level, cross-border research funding under the “Young Scientist Scheme” of the Programme. The team has been awarded a research grant of RMB 5.45 million (approximately HKD 6 million) for basic and preclinical research on the pathogenesis of osteoarthritis.
26 May 2020
Scratching the head or rubbing the hands repeatedly is common, unconscious behaviour when people are facing stress. Neuroscientists from the School of Biomedical Sciences and the Gerald Choa Neuroscience Centre of the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) have discovered a mammalian brain circuitry underlying our ability to generate adaptive responses when facing stress with strong negative emotions. The result of the study was recently published in the renowned international scientific journal Nature Communications.
Giants in history
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Archana Sharma (16 February 1932 - 14 January 2008) conducted research into plant and human genetics that expanded the understanding of both botany and human health. In relation to botany, she uncovered the means by which asexually-reproducing plants evolve into new species.
The first Thai woman to receive a degree in medicine, Margaret Lin Xavier (29 May 1898 – 6 December 1932), is best remembered for her compassion towards her less privileged patients.
In 1915, pathologist Katsusaburo Yamagiwa and his research assistant Koichi Ichikawa became the first to prove that chronic exposure to chemicals can cause cancer.
After witnessing death and suffering as a youth in his home village during World War II, Nguyễn Tài Thu (6 April 1931 – 14 February 2021) set his sights on alleviating pain by becoming a doctor. After studying Traditional Chinese Medicine in China in the 1950s, Thu returned to Vietnam to serve in military hospitals. Eventually, he became the country’s foremost practitioner of acupuncture, a technique he first learned by inserting needles into himself.
David T. Wong (born 1936) is a Hong Kong-born American neuroscientist who is best known for discovering the antidepressant drug fluoxetine, better known as Prozac.
Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
Hsien Wu (24 November 1893 – 8 August 1959) is widely regarded as the founder of biochemistry and nutrition science in China. He was the first to propose that protein denaturation was caused by the unfolding of the protein, instead of chemical alteration.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Syed Qasim Mehdi (13 February 1941 – 28 September 2016) was a Pakistani molecular biologist who was a founding member of the Human Genome Diversity Project (HGDP), which assessed human diversity by studying human migration, mutation rates, relationships between different populations, genes involved in height and selective pressure.
Tsai-Fan Yu (1911 – 2 March 2007) was a Chinese-American physician and researcher who was the first female full professor at Mount Sinai School of Medicine. She discovered that gout, a condition characterized by the painful inflammation of joints, was caused by elevated levels of uric acid in the bloodstream.
Min Chueh Chang (10 October 1908 – 5 June 1991) was a Chinese-American biologist who studied fertilization in mammalian reproduction.
A Japanese surgeon, Tetsuzo Akutsu (20 August 1922 – 9 August 2007) built the first artificial heart capable of keeping an animal alive.