20 Sep 2021
Researchers at the National Dental Research Institute Singapore (NDRIS) have developed a novel device that aims to limit the spread of aerosols generated during dental procedures, thereby lowering the risk of COVID-19 crosscontamination in the dental setting.
17 Sep 2021
A specially designed lipid nanoparticle could deliver immune-signaling molecules into liver macrophage cells to overcome resistance to anti-tumor immunotherapy.
16 Sep 2021
Genetic and epigenetic profiling of hundreds of hepatoblastoma tumors have revealed many of its secrets, long unknown to those researching and treating what is the most common type of liver tumor in children.
15 Sep 2021
New research published in Stem Cell Reports has found elevated cholesterol supply from astrocytes to neurons in the model of Alzheimer's disease (AD) brains, suggesting that modulating brain cholesterol could be explored in the search of treatment options for the devastating, degenerative disease.
14 Sep 2021
Cochlear implants help deaf patients in hearing, yet the current technology remains far from perfect. A research team led by scientists from City University of Hong Kong (CityU) has shown that neonatally deafened rats could be trained with cochlear implant stimulation to restore the ability to locate the directions of sound origins. The finding implies that shortcomings in current cochlear implant technology, rather than the lack of auditory experience in early childhood, maybe the reason why cochlear implant patients usually have poor spatial hearing performance.
13 Sep 2021
iCeMS scientists and colleagues have designed a molecular code that powers up cancer-fighting immune cells.
13 Sep 2021
Abnormally high levels of DNA methylation have been identified in dogs exposed to high levels of lead near a mining area in Kabwe, Zambia, by a team of scientists from Japan and Zambia.
10 Sep 2021
Magnetic patterns in meteorites, Treating mitochondrial diseases, underwater sensors and a broad COVID-19 vaccine in the September Editor's Choice. Plus, what's it like to communicate vaccine research in a pandemic and Asia Research News 2022.
10 Sep 2021
Researchers have identified a potential reason why lower numbers of COVID cases have appeared amongst smokers compared to non-smokers, even as other reports suggest smoking increases severity of the disease.
09 Sep 2021
Researchers at the University of Tsukuba in Japan show that low metabolic flexibility is associated with reduced fat metabolism during sleep.
09 Sep 2021
Researchers from the University of Tsukuba and Kyoto University find that capillary blood flow in the brain, which is important for delivering oxygen and nutrients and removing waste products, is increased in mice during the dream-active phase of sleep.
09 Sep 2021
Researchers from University of Tsukuba in collaboration with Yamagata University scientists find that exposure to light with less blue before sleep is better for energy metabolism. Extended exposure to light during nighttime can have negative consequences for human health. But now, researchers from Japan have identified a new type of light with reduced consequences for physiological changes during sleep.
08 Sep 2021
A research team led by Hiroshima University Professor Satoshi Okada has determined that enhanced bone resorption activity due to a faulty immune response may underpin multifocal osteomyelitis — painful, chronic bone infections — in children with MSMD, a rare genetic condition resulting from a range of immune system mutations.
08 Sep 2021
A research group has discovered an interorgan network between the mammary glands and the small intestine that plays an essential role in transferring antibodies via breastfeeding.
07 Sep 2021
Recreating major pathological features of Parkinson’s disease in a lab-grown, human mini-brain will help researchers to explore new treatments. This is the first time that Lewy bodies, a hallmark of Parkinson’s disease in patients’ brains, have been produced in the laboratory, offering new insights into the disease.
06 Sep 2021
A comprehensive, systematic meta-analysis conducted by HKBU scientists found a significant association between exposure to PM2.5, i.e., fine particulates with equivalent diameters of less than 2.5 microns suspended in the air, and neurological disorders. These include stroke, dementia, Alzheimer's disease, Parkinson's disease and autism spectrum disorder (ASD). Neurological disorders are the leading cause of disability and the second leading cause of death worldwide, posing serious challenges to global health.
06 Sep 2021
Using data from 1,107 patients dating back over 30 years, researchers have connected prognostic impact to poorly differentiated tumor size in hepatocellular carcinoma. Data confirmed previous findings that after resection, <2 cm sized tumors had excellent long-term outcomes. However, ≥2 cm and ≥5 cm sizes shared a risk of early recurrence with the latter size also at risk of early extrahepatic recurrence.
01 Sep 2021
KAIST researchers have used whole-genome sequencing to track the development from a single fertilized-egg to a human body.
27 Aug 2021
The healthcare systems of the mainland and Hong Kong face similar challenge of spiralling costs in the face of increasing demand from a more prosperous and aging population, and a surge in non-communicable diseases. Hong Kong government reforms aim to reduce the burden on the over-stretched public healthcare system. The public policy research by Dr Alex He Jingwei, Associate Professor and Associate Head (Research and Development) at the Department of Asian and Policy Studies, The Education University of Hong Kong, has contributed to knowledge informing large-scale reforms in both mainland China and Hong Kong, and generated public debate. His work provided a significant reference in a major government-supported reform blueprint for the mainland’s healthcare system, much of it now being implemented in the State Council’s 13th Five-Year Plan (2016-2020), engagement with policymakers, and media engagement in mainland China and Hong Kong, reaching an audience of at least a billion people.
27 Aug 2021
Speakers announced for the 10th edition of IPI’s premier technology matching event
26 Aug 2021
A multi-functional, small molecule can tag mutant genetic sequences inside mitochondria for removal.
26 Aug 2021
Distinguished Professor Reiko Kishi of the Hokkaido University Center for Environmental and Health Sciences was honored with the International Society for Environmental Epidemiology (ISEE)’s prestigious 2021 John Goldsmith Award, on August 26, 2021.
25 Aug 2021
A novel CT scan-based approach has revealed significant changes in a parameter indicating lung destruction in some asthmatics. This finding could lead to more personalized treatments for asthma accompanied by persistent airflow limitation.
18 Aug 2021
Through a follow-up analysis of d-ROM values taken pre- and post-cardiopulmonary exercise tests, researchers have found that heart failure patients with increased oxidative stress during exercise have a poorer prognosis - leading to potential design of exercise routines around individual patients.
12 Aug 2021
The nutritional status of children under five in Sri Lanka has not shown a significant improvement for the last 20 years. It has also been lagging behind most of the other health and social indicators on children. IPS research shows that household income, inadequate nutrient intake, breastfeeding practices, mothers’ education, etc., play a major role in child undernutrition in Sri Lanka. Moreover, given significant losses in household income experienced at the hands of the COVID-19 pandemic, nutrient intake may have declined further over the past year. As such, it would be a challenging task for health planners to develop effective strategies to minimise undernutrition among children under five years. This article highlights some of the facts contributing to child undernutrition in Sri Lanka and suggests ways to address this critical issue.
11 Aug 2021
Researchers discover a link between an increase in protein Ba of the complement immune system and the eventual development of thrombotic microangiopathy in patients who have received an allogeneic hematopoietic stem cell transplantation.
10 Aug 2021
A new, energy-efficient method of electrical brain stimulation developed by researchers from the Daegu Gyeongbuk Institute of Science and Technology could aid stroke rehabilitation and has few side effects.
05 Aug 2021
People with autism spectrum disorder interpret facial expressions differently. A group of Tohoku University researchers have revealed more about how this comes to be. They induced abnormalities into a neural network model to explore the effects on the brain’s learning development.
04 Aug 2021
Sleeping safe and sound is one of human’s most fundamental needs to stay reenergized and maintain our bodily functions. How does hearing environmental sounds influence our sleeping quality? Assistant Professor Junta Tagusari from the Laboratory of Regional Environmental Issues, Graduate School of Engineering, is investigating the best method to measure noises and how they affect human health.
Giants in history
Flora Zaibun Majid ( 1939–2018) was an accomplished Bangladeshi researcher in botany and nutrition science and the first female chairperson of the Bangladesh Council of Scientific and Industrial Research.
Iranian physician and bacteriologist Azar Andami (8 December 1926 – 19 August 1984) developed a cholera vaccine to combat an outbreak that swept through the Middle East, India, Southeast Asia, and Africa in 1937.
Irene Ayako Uchida’s (8 April 1917 – 30 July 2013) strides to understand genetic diseases such as Down syndrome paved the way for early screening of chromosomal abnormalities in foetuses.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
Maggie Lim (5 January 1913 – November 1995) was a Singaporean physician who promoted family planning and expanded the access to clinics to improve the quality of life for mothers and children in Singapore’s early days.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
The founder of the Adyar Cancer Institute in India, Muthulakshmi Reddy (30 July 1886 – 22 July 1968), fought to uplift women and girls from impoverished situations.
Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Archana Sharma (16 February 1932 - 14 January 2008) conducted research into plant and human genetics that expanded the understanding of both botany and human health. In relation to botany, she uncovered the means by which asexually-reproducing plants evolve into new species.
The first Thai woman to receive a degree in medicine, Margaret Lin Xavier (29 May 1898 – 6 December 1932), is best remembered for her compassion towards her less privileged patients.
In 1915, pathologist Katsusaburo Yamagiwa and his research assistant Koichi Ichikawa became the first to prove that chronic exposure to chemicals can cause cancer.
Filipino chemist and pharmacist Manuel A. Zamora (29 March 1870 – 9 July 1929) is best remembered for his discovery of the tiki-tiki formula to combat beriberi, a disease caused by Vitamin B1 deficiency.
After witnessing death and suffering as a youth in his home village during World War II, Nguyễn Tài Thu (6 April 1931 – 14 February 2021) set his sights on alleviating pain by becoming a doctor. After studying Traditional Chinese Medicine in China in the 1950s, Thu returned to Vietnam to serve in military hospitals. Eventually, he became the country’s foremost practitioner of acupuncture, a technique he first learned by inserting needles into himself.
David T. Wong (born 1936) is a Hong Kong-born American neuroscientist who is best known for discovering the antidepressant drug fluoxetine, better known as Prozac.
Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
Hsien Wu (24 November 1893 – 8 August 1959) is widely regarded as the founder of biochemistry and nutrition science in China. He was the first to propose that protein denaturation was caused by the unfolding of the protein, instead of chemical alteration.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Syed Qasim Mehdi (13 February 1941 – 28 September 2016) was a Pakistani molecular biologist who was a founding member of the Human Genome Diversity Project (HGDP), which assessed human diversity by studying human migration, mutation rates, relationships between different populations, genes involved in height and selective pressure.
Tsai-Fan Yu (1911 – 2 March 2007) was a Chinese-American physician and researcher who was the first female full professor at Mount Sinai School of Medicine. She discovered that gout, a condition characterized by the painful inflammation of joints, was caused by elevated levels of uric acid in the bloodstream.
Min Chueh Chang (10 October 1908 – 5 June 1991) was a Chinese-American biologist who studied fertilization in mammalian reproduction.
A Japanese surgeon, Tetsuzo Akutsu (20 August 1922 – 9 August 2007) built the first artificial heart capable of keeping an animal alive.