Science

A team of international researchers, led by Associate Professor Masaki Eda of the Hokkaido University Museum, have discovered that the oldest type of poultry ever domesticated may have been geese. The study involved interdisciplinary research of bones excavated from Tianluoshan site in the lower Yangtze River valley, Zhejiang Province, China.

The molecule trimethylamine N-oxide (TMAO) can be used to reversibly modulate the rigidity of microtubules, a key component of molecular machines and molecular robots.

Giants in History: Purnima Sinha (12 October 1927 – 11 July 2015), the first Bengali woman to receive a doctorate in physics, analysed clay structures using x-ray equipment that she built from salvaged World War II-era parts.

Climate changes in the tropical Pacific have temporarily put the brakes on rapid warming and ice melting in Greenland.

東京工業大学地球生命研究所（ELSI）は、エビデンスに基づくアウトリーチを展開することで、科学コミュニケーション専門トレーニングの大切さを積極的に発信している。日本の高等教育機関と研究機関での研究アウトリーチ活性化の先駆けとなることを目指す。

Distinguished Professor Hiroki Shirato of Hokkaido University is one of the nine recipients of the Japan Academy Prize in 2022, for his groundbreaking work on “Biomedical and Engineering Research about Real-time Tumor Tracking Radiotherapy/Particle Beam Therapy against Cancer.”

伝統的な日本の大学のカルチャーの殻を破り、フラットで国際的な研究所として注目を集める東京工業大学地球生命研究所（ELSI）。今年で10年目を迎えたELSIの魅力や運営のコツについて廣瀬敬前所長が語った。

東京工業大学地球生命研究所（ELSI）は今年、転機を迎える。10年前の設立当初からのテーマであった「地球と生命の起源」から踏み出し、地球外生命の可能性まで研究対象を広げていく。次期所長の関根康人教授にこれからのELSIが目指すところを聞いた。

Gene editing technology has been used to pinpoint new molecular targets for treating an aggressive form of leukemia in adults.

A team led by a Institute of Industrial Science, The University of Tokyo researcher has created a model to probe the role of emergent elastic fields in chiral molecular crystals

Giants in History: Subrahmanyan Chandrasekhar (19 October 1910 – 21 August 1995) was an Indian astrophysicist who studied the structure and evolution of stars.

A simulation of stakeholder interactions around geothermal development in Japan provides an agent-based modeling tool for understanding how achieving community consensus is achieved.

Researchers have discovered argon trapped in air-hydrate crystals in ice cores, which can be used to reconstruct past temperature changes and climate shifts.

Giants in History: Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions.

Australia's national science agency, CSIRO, will tackle Australia's plastic pollution problem, pledging to help Australia reduce 80 per cent of its plastic waste by the end of the decade.

Giants in History: Woo Jang-choon (8 April 1898 – 10 August 1959) was a Korean-Japanese agricultural scientist and botanist. Woo performed horticultural research, first in Japan, then in Korea.

Microgravity worms help solve astronaut muscle problems, CO2 recycling and drug development, Remote control of robot hand, Enabling the study of diverse Hepatitis B. Read all in the March's Editor's Choice and even more in the Asia Research News 2022 magazine.

Unlike most traditional Japanese universities, the Earth-Life Science Institute (ELSI) at Tokyo Institute of Technology has created a ‘flat’ and diverse research environment. On its ten-year anniversary, Outgoing Director Kei Hirose shares what is special about the institute and the secret behind its successful management.

The Earth-Life Science Institute (ELSI) based at Tokyo Institute of Technology will reach a turning point this year. For the first time in its 10-year history, it will extend the scope of its initial research theme, "The Origins and Evolution of the Earth and Life", to include searching for evidence of extra-terrestrial life. ELSI’s new director, Yasuhito Sekine, told Asia Research News what they hope to achieve in the next phase and how.

A research group has revealed that amyloid-β (Aβ) detected in blood is secreted from peripheral tissues (pancreas, adipose tissue, skeletal muscle, liver, etc.) that are sensitive to glucose and insulin. Also, that Aβ secreted from peripheral tissues acts as a regulator on pancreatic β-cells to suppress insulin secretion. The results of this study indicate that blood Aβ levels fluctuate significantly with diet, and special care should be taken when using blood samples as a diagnostic marker for Alzheimer's disease, such as taking blood samples during fasting.

Researchers at Kanazawa University report in Proceedings of the National Academy of Sciences a responsive molecular system that, through chemical reactions, inverses its chirality before becoming racemic.

As a result of global warming in the 21st century, the Greenland ice sheet may contribute several metres to sea-level rise in the centuries to come; however, effective climate change mitigation measures will greatly reduce its decay.

Mathematician Yukari Ito was excited at first to work from home. There was no need to commute to her office at the Kavli Institute for the Physics and Mathematics of the Universe, where she is professor, and she could attend seminars by mathematicians around the world from her living room. But there are also challenges, so she hopes some things will go back to the way they used to be.

Researchers aim to streamline the time- and resource-intensive process of screening ligands during catalyst design by using virtual ligands.

A recent summertime climate pattern could be driving co-occurring European heatwaves and large-scale wildfires over Siberia, Canada and Alaska.

The Global Navigation Satellite System associated with a Japanese cell phone carrier can enhance monitoring of crustal deformation changes for earthquake early warning models.

Giants in History: Roseli Ocampo-Friedmann (23 November 1937 – 4 September 2005) was a Filipino-American scientist whose research focused on cyanobacteria and microorganisms that inhabit extreme environments.

- New HPHAC analogues with an embedded nonbenzenoid aromatic ring have been synthesized. - The newly synthesized HPHACs exhibit multistep redox properties and their dicationic species showed an aromatic nature based on macrocyclic conjugation. - Methylation on the nonbenzenoid aromatic ring resulted in the development of "antiaromaticity".

A research team led by the National Institute for Physiological Sciences and joined by Hokkaido University explored the role of pain neurons in the regulation of endotoxic death. They found that peptide named Reg3γ acts as a pain neuron-enriched brain-targeted hormone that protects the host from endotoxic death.

Scientists develop a method to genetically label neurons with a single gene of interest in mice by combining the anterograde transsynaptic spread of adeno-associated virus serotype 1 (AAV1) with intersectional gene expression. In two distinct circuits: the retina/primary visual cortex to the superior colliculus and the bilateral motor cortex to the dorsal striatum, injections of AAV1 expressing either Cre or Flpo recombinases and the Cre/Flpo double-dependent AAV into two upstream regions and the downstream region, respectively, were used to label postsynaptic neurons receiving inputs from the two upstream regions.